Digital Commons @ Harrisburg University of Science and Technology
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mRNA Vaccine Technology for Infectious Diseases
No full textmRNA vaccines have been established as a promising alternative to conventional vaccines over the last decade. mRNA therapeutics do not use inactivated viruses, which makes them non-immunogenic, easily degradable and without possessing the risk of insertional mutagenesis. mRNA vaccines use a standard platform for development of prophylactic and infectious diseases which makes mRNA vaccine platform a breakthrough technology in the field of therapeutics. Various aspects of mRNA structure come into play when developing mRNA vaccines and this review focuses on the translation, stability, immunogenicity related to mRNA vaccines and their delivery methods. The nuances of testing the quality of mRNA vaccines, regulatory aspects and market trends are covered in the review would provide a more comprehensive review of mRNA vaccines in addition to the scientific and technical aspects
The relationship between pets owned and gender amongst college students
Get PDFThere is a gap between the number of men and women that own dogs. The Mintel Press Team states that 71% of men aged 18-44 own a dog compared to 60% of their female counterparts (Mintel Press Team, 2016, para: 1). While this statistic includes people who are college-aged, it does not mention college students specifically. Thus, research into the relationship between pets owned and gender amongst college students is an important topic that warrants looking into
Harrisburg Workforce Study
Get PDFHarrisburg University proposes an exploratory case study to examine workforce participation and patterns in the downtown Harrisburg Area as part of its mission to support business creation and economic development. This research interest has resulted from uncertainty regarding the number of local employees returning to work in a face-to-face environment in the post-pandemic era compared to other metropolitan areas in the United States.
This preliminary research seeks to provide empirical evidence of the current and predictive state of workforce participation in Harrisburg for the purposes of informing urban planners, downtown business owners and other decision makers concerned with many aspects associated with living and working downtown. This research will collect quantitative and qualitative data from organizations in the Harrisburg regions of Dauphin, Cumberland and Perry Counties via online surveys. Subsequent results can be used as the basis for further research measuring the scope and magnitude of issues identified by area business leaders
Acceptable Behavior: Moderating harassment in Twitch micro-communities
No full textFor many people, online communities have become an indispensable component of modern social life. Unfortunately, negative social interactions within these communities can be harmful to its members. Research has shown that toxic behavior can negatively impact the mental health and well-being within online communities. This presentation will illustrate using a linguistic inquiry approach for classifying inappropriate behavior in online communities. Our research shows how group dynamics and machine learning can mitigate harassment for the safety and well-being of online community members
Why Do Relationships Matter to Project Managers? 3 Elements to Integrate into Every Project Manager Tool-Kit
Get PDFAbstract
Emotional intelligence is one of the essential attributes of success in the workplace and life. It is a skill that can be learned and developed. The ability to manage emotions is also a part of it. Emotional intelligence can be taught, practiced, and mastered by anyone who wants to become a better manager. It is not just about managing your emotions but being able to manage them effectively if you want to become a better leader. One of the hallmarks of effective project leadership is building constructive relationships. Relationship building is essential because project managers do not typically have authority over the team. If projects are to be successfully completed, the project manager must rely on working with others – this requires relationships. The more complex the project, the more people want your attention. It is impossible to do justice to them all, so it is time to prioritize the list to keep your most important working relationships manageable and growing
THE RELATIONSHIP BETWEEN HISTORIC REDLINING AND URBAN HEAT ISLAND EXPOSURE IN HARRISBURG, PENNSYLVANIA.
No full textNationwide, urban residents experience disproportionately higher levels of heat intensity due to a higher proportion of built environments to natural landscaping as compared to suburban and rural areas. Several studies have suggested that this urban heat island effect is not equitably distributed across cities as a legacy of past redlining policies, with low-income residents of color at a higher risk of experiencing heat-related illness and stress. This research aims to examine the relationship between the historic Home Owners’ Loan Corporation (HOLC) zoning districts within the City of Harrisburg and Surface Urban Heat Index values. To accomplish this, digitized HOLC zoning districts from 1935 to 1936 were overlaid on a surface heat map generated using Landsat imagery. Surface heat values were then sampled across each district using 100 randomly generated points stratified by zone and analyzed using a single-factor ANOVA. Since tree canopy cover plays a large role in mitigating land surface heat via evapotranspiration, the percent canopy cover within each zone was calculated. Residents living in areas historically zoned as desirable were significantly (df = 3, p\u3c0.01) cooler than areas historically zoned as static, declining, or hazardous. While static and declining zones had canopy coverage similar to that of the city overall, the desirable zones had significantly higher proportions of canopy cover and hazardous zones has significantly lower proportions of canopy coverage than expected. To further inform policy efforts, this research identified areas such as vacant lots and unimproved greenspace that can be prioritized for revitalization
Modeling the Effect of the US Supreme Court Ruling to Remove CO2 Caps on Atmospheric PM2.5 in Pennsylvania
No full textOn July 19, 2022, the US Supreme Court ruled that the Environmental Protection Agency (EPA) could no longer cap CO2 emissions from coal-fired power plants under the 1970 Clean Air Act. The impact of this ruling not only increases carbon emissions but also influences atmospheric concentrations of ozone and PM2.5. Overall, coal-fired power plants equipped with air scrubbers to reduce PM2.5 still contribute to 20% of the total PM2.5 atmospheric concentration. PM2.5 can penetrate the respiratory system and has been linked to both respiratory and cardiovascular diseases. To investigate the impact of the US Supreme Court’s decision on the citizens of Pennsylvania, this study used ArcGIS Pro 3.0 to model expected changes in PM2.5 atmospheric concentrations by county after the removal of CO2 emission caps. Additionally, the study modeled expected PM2.5 atmospheric concentrations if the caps were permitted to continue. The modeled concentrations were then run through EPA’s BenMap tool to estimate the number of asthma, lung cancer, and heart disease cases that can be attributed to each scenario. The results of this project can be used as an educational tool to inform the public of the risks associated with not having a greenhouse gas reduction law
