Mediamusic (E-Journal)
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The needs of women and their partners regarding professional smoking cessation support during pregnancy:A qualitative study
No full textBACKGROUND: Despite the health risks of smoking, some women continue during pregnancy. Professional smoking cessation support has shown to be effective in increasing the proportion of pregnant women who quit smoking. However, few women actually make use of professional support.AIM: To investigate the needs of women and their partners for professional smoking cessation support during pregnancy.METHODS: Semi-structured interviews were held with pregnant women and women who recently gave birth who smoked or quit smoking during pregnancy, and their partners, living in the north of the Netherlands. Recruitment was done via Facebook, LinkedIn, food banks, baby stores and healthcare professionals. The interviews were recorded, transcribed and thematically analysed.RESULTS: 28 interviews were conducted, 23 with pregnant women and women who recently gave birth, and five with partners of the women. The following themes were identified: 1) understanding women's needs, 2) responsibility without criticism, and 3) women and their social network. These themes reflect that women need support from an involved and understanding healthcare professional, who holds women responsible for smoking cessation but refrains from criticism. Women also prefer involvement of their social network in the professional support.CONCLUSION: For tailored support, the Dutch guideline for professional smoking cessation support may need some adaptations. The adaptations and recommendations, e.g. to involve women and their partners in the development of guidelines, might also be valuable for other countries. Women prefer healthcare professionals to address smoking cessation in a neutral way and to respect their autonomy in the decision to stop smoking.</p
Republicanism and/or Relational Egalitarianism?
No full textWhat is the relationship between republicanism and relational egalitarianism? According to Andreas Schmidt, republicanism, in particular Pettit’s theory of republicanism, is able to capture some relations as objectionable which relational egalitarianism cannot, to wit, relations of mutual domination. This shows that relational egalitarianism is inadequate. In this paper, I explore the relationship between republicanism and relational egalitarianism and argue, first, that Schmidt is wrong. Relational egalitarianism, on a plausible understanding, does object to relations of mutual domination. I then argue that relational egalitarianism, unlike republicanism, is able to capture why some relationships involving racism are objectionable. I end the paper by arguing that we should not see the views as competitors: republicanism, on a plausible understanding, provides a necessary condition of what it means to relate as equals (i.e. non-domination), whereas relational egalitarianism provides necessary and jointly sufficient conditions of what it means to relate as equal
Exploring change in networks supporting the deliberate practice of popular musicians
No full textPopular musicians are embedded in dynamic networks supporting their expertise development across different phases. During these phases, network actors support different aspects of deliberate practice in which a musician needs to engage to become an expert. Research in the domain of music is scarce in terms of investigating the change in the supportive networks of deliberate practice over time. Semi-structured interviews with five expert and five intermediate popular musicians were used to explore changes in networks supporting the deliberate practice during their childhood, apprenticeship, and career phases. Egocentric network analysis revealed that networks supporting the deliberate practice of expert musicians are more dynamic and less stable when considering the different phases than the networks of intermediates. In addition, experts are supported by a larger number of network actors during the developmental phases. In both groups, the number of network actors decreased as the musicians progressed through the phases. This decrease was more precipitous between the childhood and apprenticeship phases. Overall, expertise development as a popular musician depends not only on deliberate practice but also on the diversity and change in an adaptive support network from childhood to adulthood
Contemporary Humanitarian Intervention:Beyond Rules-Based International Order
No full textThis chapter traces the international practice of humanitarian intervention from its conceptual and practical inceptions to its current form. After specifying what we mean when we talk about humanitarian intervention, it outlines how ideas around this practice transformed from the late sixteenth century until they supposedly celebrated their heyday after the Cold War in a so-called “rules-based international order.” This chapter proceeds to highlight certain critiques of humanitarian intervention based on notions of state sovereignty, the practical difficulties of “successfully” conducting and/or legitimizing intervention, the relationships between powerful and less powerful states, and the question of humanity. Subsequently, it places these critiques in the context of debates about the supposed “end of the rules-based international order.” While these debates signal a diminishing global enthusiasm for human rights protection through humanitarian intervention, this chapter argues that both this international order and the practice of humanitarian intervention are going through a transition rather than fully coming to an end. While this chapter therefore anticipates an enhanced global emphasis on domestic human rights protection and prudence about foreign intervention, it does not foresee a termination of humanitarian intervention per se
Source Seeking Control of Unicycle Robots with 3-D-Printed Flexible Piezoresistive Sensors
No full textWe present the design and experimental validation of source seeking control algorithms for a unicycle mobile robot that is equipped with novel 3D-printed flexible graphene-based piezoresistive airflow sensors. Based solely on a local gradient measurement from the airflow sensors, we propose and analyze a projected gradient ascent algorithm to solve the source seeking problem. In the case of partial sensor failure, we propose a combination of Extremum-Seeking Control with our projected gradient ascent algorithm. For both control laws, we prove the asymptotic convergence of the robot to the source. Numerical simulations were performed to validate the algorithms and experimental validations are presented to demonstrate the efficacy of the proposed methods
Phosphoregulation of the autophagy machinery by kinases and phosphatases
No full textEukaryotic cells use post-translational modifications to diversify and dynamically coordinate the function and properties of protein networks within various cellular processes. For example, the process of autophagy strongly depends on the balanced action of kinases and phosphatases. Highly conserved from the budding yeast Saccharomyces cerevisiae to humans, autophagy is a tightly regulated self-degradation process that is crucial for survival, stress adaptation, maintenance of cellular and organismal homeostasis, and cell differentiation and development. Many studies have emphasized the importance of kinases and phosphatases in the regulation of autophagy and identified many of the core autophagy proteins as their direct targets. In this review, we summarize the current knowledge on kinases and phosphatases acting on the core autophagy machinery and discuss the relevance of phosphoregulation for the overall process of autophagy.</p
Employees Receiving Inpatient Treatment for Common Mental Disorders in Germany:Factors Associated with Time to First and Full Return to Work
No full textPurpose In Germany, return to work (RTW) after inpatient treatment for common mental disorders (CMDs) is a complex process at the intersection of the mental healthcare system and the workplace. This study examined (1) the time to first and full RTW and (2) associated factors among employees receiving inpatient treatment for CMDs. Methods In this prospective cohort study, employees receiving inpatient psychiatric or medical rehabilitation treatment for CMDs were interviewed by phone during their last week before discharge. Follow-up interviews were conducted after 6, 12, and 18 months. Health-, personal, and work-related factors were used from baseline measurement. Parametric survival analysis was conducted to identify factors associated with time to first and full RTW. Results A total of N = 269 participants who stayed at a psychiatric clinic or a medical rehabilitation facility were included. Almost all participants (n = 252, 94%) from both treatment settings reported a first RTW and a full RTW. The time to first and full RTW was shortest among participants from medical rehabilitation (both median 6 days) and longer among participants from psychiatric treatment (median 17 days to first RTW and 73 days to full RTW). While only health-related and personal factors were associated with time to first RTW, leadership quality and needed individual RTW support were associated with time to full RTW. Conclusions More attention to work accommodation needs for RTW in clinical practice and coordinated actions towards RTW in collaboration with key RTW stakeholders in the workplace may support a timely RTW.Clinical Registration Number DRKS00010903, retrospectively registered.</p
Update on management of atrial fibrillation in heart failure:a focus on ablation
No full textAtrial fibrillation is increasingly encountered in patients with heart failure. Both diseases have seen tremendous rises in incidence in recent years. In general, the treatment of atrial fibrillation is focused on relieving patients from atrial fibrillation-related symptoms and risk reduction for thromboembolism and the occurrence or worsening of heart failure. Symptomatic relief may be accomplished by either (non-)pharmacological rate or rhythm control in combination with optimal therapy of underlying cardiovascular morbidities and risk factors. Atrial fibrillation ablation has been performed in patients without overt heart failure successfully for many years. However, in recent years, attempts have been made for patients with heart failure as well. In this review, we discuss the current literature describing the treatment of atrial fibrillation in heart failure. We highlight the early rate versus rhythm control studies, the importance of addressing underlying conditions and treatment of risk factors. A critical evaluation will be performed of the catheter ablation studies that have been performed so far in light of larger (post-hoc) ablation studies. Furthermore, we will hypothesise the role of patient selection as next step in optimising outcome for patient with atrial fibrillation and heart failure.</p
Long-term outcomes of atrioventricular septal defect and single ventricle:A multicenter study
No full textOBJECTIVE: The study objective was to analyze survival and incidence of Fontan completion of patients with single-ventricle and concomitant unbalanced atrioventricular septal defect.METHODS: Data from 4 Dutch and 3 Belgian institutional databases were retrospectively collected. A total of 151 patients with single-ventricle atrioventricular septal defect were selected; 36 patients underwent an atrioventricular valve procedure (valve surgery group). End points were survival, incidence of Fontan completion, and freedom from atrioventricular valve reoperation.RESULTS: Median follow-up was 13.4 years. Cumulative survival was 71.2%, 70%, and 68.5% at 10, 15, and 20 years, respectively. An atrioventricular valve procedure was not a risk factor for mortality. Patients with moderate-severe or severe atrioventricular valve regurgitation at echocardiographic follow-up had a significantly worse 15-year survival (58.3%) compared with patients with no or mild regurgitation (89.2%) and patients with moderate regurgitation (88.6%) (P = .033). Cumulative incidence of Fontan completion was 56.5%, 71%, and 77.6% at 5, 10, and 15 years, respectively. An atrioventricular valve procedure was not associated with the incidence of Fontan completion. In the valve surgery group, freedom from atrioventricular valve reoperation was 85.7% at 1 year and 52.6% at 5 years.CONCLUSIONS: The long-term survival and incidence of Fontan completion in our study were better than previously described for patients with single-ventricle atrioventricular septal defect. A concomitant atrioventricular valve procedure did not increase the mortality rate or decrease the incidence of Fontan completion, whereas patients with moderate-severe or severe valve regurgitation at follow-up had a worse survival. Therefore, in patients with single-ventricle atrioventricular septal defect when atrioventricular valve regurgitation exceeds a moderate degree, the atrioventricular valve should be repaired.</p
Learning an L2 and L3 at the same time:Help or hinder?
No full textThere is quite a bit of evidence showing that the experience of learning an L2 will help in learning an L3, but as far as we know, very little research has investigated the possible impact of L3 learning on the already existing and still developing L2 system within the learner. According to Complex Dynamic Systems Theory (CDST), language development depends on limited resources. In simultaneous L2 and L3 (L2 + L3) learners, these resources have to be used for learning two languages, reducing the resources available for L2 learning. This might lead, firstly, to a slower L2 development in L2 + L3 learners than in L2 only learners, and secondly, to more variability in the L2 during the learning process. In the current study, we traced the L2 English writing proficiency scores (both in terms of gains and variability) of two groups of L1 Chinese learners within one academic year. One group learnt English only (L2) and the other group learnt English and Russian simultaneously. Results show that the L2 + L3 learners did not develop their L2 to a lesser extent than the L2 learners did, but they showed more variability over time in one sub-area (fluency) of L2 writing proficiency. The implications are discussed