Journal of Patan Academy of Health Sciences
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Comparison of efficiency between Risk Malignancy Index 1 and Risk Malignancy Index 2 in diagnosing ovarian tumor
Introduction: The risk of malignancy index (RMI) is a validated clinical tool for stratifying risk of ovarian lesions. It is a scoring system based on menopausal status, ultrasound finding and CA-125 level. Various modifications have been made on scoring system to enhance its efficiency. The commonly used RMI is RMI 1 however recent studies suggest higher efficiency of RMI 2 over RMI 1. So, this study compares the efficiency of RMI 1 and RMI 2 on differentiating malignant ovarian tumor over benign one.
Method: This analytical cross-sectional study done at Patan hospital included 172 women who underwent operation for ovarian tumor. Both RMI 1 and RMI 2 were calculated using Ultrasound score, CA-125 value and menopausal status and compared with histopathological diagnosis. The cut-off value was 200 for both RMI 1 and RMI 2 in discriminating malignancy. Chi square test and Receiver Operator Characteristics (ROC) curves were calculated.
Result: Among 172 patients, 23 had malignant and 149 had benign ovarian tumor. The area under ROC curve for RMI 1 and RMI 2 was 0.973 and 0.969 respectively, which was statistically significant. The sensitivity and specificity of RMI 1 was 86.96% and 98.64%, whereas sensitivity and specificity of RMI 2 was 91.3% and 97.23% respectively. Similarly, positive predictive value (PPV) and negative predictive value (NPV) of RMI 1 was 90.9% and 97.98%, and that of RMI 2 was 84% and 88.63%, respectively.
Conclusion: RMI 1 has higher specificity, PPV and NPV whereas RMI 2 has higher sensitivity in diagnosing ovarian tumor
Study on the efficacy of Centella asiatica Linn. on Helping Students to Improve Memory and Attention for Learning
The role of group identification in the wellbeing of Spaniards with gypsy ethnicity
This study examines the protective role of ethnic identity in the psychological well-being of the Roma population in Spain, showing that affective identity affirmation predicts well-being and life satisfaction
[Poster Pre-conference ISR2019] "Moving beyond the exploration of culture based on national borders: cross-cultural emotion perception within China"
Additional Figures and Output: 2021 Frontiers Neural Circuits and Hippocampus papers
Extra figures and network simulation outputs for our "...minimal and detailed CA1 microcircuit" pape