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Summary of: Evaluating community engagement efforts in a clinical and translational research initiative
Get PDFCommunity engagement is a core element of translational science, yet tools to assess its quality and reach remain limited. This study evaluated the Northern New England Clinical and Translational Research Network’s efforts to strengthen community academic partnerships through its Community Engagement and Outreach Core using the PARTNER CPRM platform, which combines network analysis with survey-based trust and value metrics.
Study found @ Evaluating community engagement efforts in a clinical and translationa by Kelly Finck Waters, Brenda Joly et al.https://knowledgeconnection.mainehealth.org/nnectr/1010/thumbnail.jp
The importance of the anterior nasal spine in predicting soft tissue movement in maxillary orthognathic surgery
No full textBACKGROUND: The aim of this study was to compare and analyze the correlation between changes in maxillary hard tissue landmarks and nasolabial soft tissue points in patients with skeletal Class II and Class III malocclusion following Le Fort I osteotomy. METHODS: From 2017 to 2022, patients who underwent Le Fort I osteotomy were recruited in this retrospective study. Three hard tissue landmarks on the maxilla and twelve soft tissue landmarks on the nose and lips were selected for measurement. A Pearson correlation coefficient was used to analyze the coefficient correlations between hard- and soft-tissue changes according to the sagittal and vertical directions. Ratios with significant correlation were calculated. RESULTS: Totally 219 patients were enrolled. In skeletal Class III malocclusion, there is a widespread and significant correlation between the ANS point and A point in both the sagittal and vertical directions with the nasolabial soft tissue point. However, in skeletal Class II malocclusion, the correlations between hard- and soft-tissue points are relatively weak. Moreover, as one moves further away from the anterior nasal spine, the correlation between hard- and soft-tissue weakens. CONCLUSION: In comparison to skeletal Class II malocclusion, skeletal Class III malocclusion exhibits a stronger correlation between the movement of the ANS and A points and changes in nasolabial soft tissue landmarks, particularly in the sagittal direction. This study suggests that changes in the position of the anterior nasal spine may play a potentially significant role in predicting the post-orthognathic surgery nasolabial soft tissue morphology in patients with skeletal Class III malocclusion
DERM-SUCCESS FDA Pivotal Study: A Multi-Reader Multi-Case Evaluation of Primary Care Physicians\u27 Skin Cancer Detection Using AI-Enabled Elastic Scattering Spectroscopy
No full textBACKGROUND: Elastic Scattering Spectroscopy (ESS), an optical tissue sampling technique, distinguishes between benign and malignant tissue in vivo without the need to perform a surgical biopsy. A handheld device that employs ESS enabled with an artificial intelligence algorithm was developed as an objective tool to aid primary care physicians (PCPs) in their management of lesions suspicious for skin cancer. The aim of this study was to assess and compare the diagnostic and management performance of PCPs with and without the use of the ESS device in detecting skin cancer. METHODS: In this clinical utility study, 108 PCPs evaluated 100 skin lesion cases (50 aided with the device output and 50 unaided by the device). For each case, PCPs provided a diagnosis, management decision, and level of confidence in that decision initially without, and then subsequently with, device output. Sensitivity, specificity, AUC, and confidence in their assessment prior to, and then with, device output were compared. RESULTS: With visual assessment assisted by device output, diagnostic sensitivity increased significantly from 71.1% to 81.7% (P = .0085) and referral sensitivity increased significantly from 82.0% to 91.4% (P = .0027) compared to visual assessment only. Device-aided diagnostic specificity decreased from 60.9% to 54.7% (P = .1896), and referral specificity decreased from 44.2% to 32.4% (P = .0256). Overall management performance (ie, AUC) also increased from 0.708 to 0.762, and increased from 0.567 to 0.682 for lesions which physicians reported low confidence in their unassisted management decision. Physicians reporting high confidence in their management assessment increased from 36.8% to 53.4%. CONCLUSION: Use of the ESS device output by PCPs significantly improved their diagnostic and management sensitivities as well as their overall management performance. The findings suggest the ESS device can improve PCP skin cancer detection and confidence in their skin lesion evaluation and management
Phantom Limb Pain Assessment Tools: A Literature Review Exploring Strengths and Limitations
No full textOBJECTIVE: To identify and categorize the pain instruments used to evaluate phantom limb pain (PLP), phantom limb sensations (PLSs), and residual limb pain (RLP) stratified by frequency of use, instrument completion time, and inclusion of descriptive terms to distinguish between the 3 phenomena. DATA SOURCES: MEDLINE/PubMed and Google Scholar from 1986 to 2024. STUDY SELECTION: Cross-sectional, cohort, and case-control studies investigating the prevalence of PLP in adults (18y or older) with surgical and traumatic upper or lower limb amputation. DATA EXTRACTION: Studies were identified and their methods were evaluated for mention of instruments used to assess for PLP. Tools were then evaluated for frequency of usage, completion time, differentiation of pain and sensations after limb amputation, and qualitative assessment using descriptor words associated with PLP and PLSs. DATA SYNTHESIS: The review included 44 studies and identified 25 tools (5 unidimensional and 20 multidimensional). Unidimensional pain scales, particularly the Numeric Rating Scale, were the most frequently used. Of the multidimensional instruments identified, 9 of them were specific to PLP, and 6 distinguished between PLP, PLS, and RLP. Only one multidimensional instrument that was specific to PLP used descriptor words to differentiate between PLP and PLS. No tool was assessed for all 3 conditions and used descriptor words to distinguish between PLP and PLSs. CONCLUSIONS: Based on this systematic review, no PLP-specific instrument is suitable for standardizing the diagnosis of PLP in its current form. Further research is needed to establish a standardized tool that can reliably distinguish between PLP, PLS, and RLP while incorporating qualitative assessments to ensure accurate diagnosis
From Harm to Healing: Centering Towards Black and Ethnic Minority in Birth Equality
Get PDFPICOT Question: In ethnic minority pregnant individuals, does anti racism training for healthcare providers improve the birthing experience compared to standard care?https://knowledgeconnection.mainehealth.org/nurseresidency/1125/thumbnail.jp
Updates on the BBCH Pediatric Aerodigestive Clinic Care Model
No full textCME available for 1 year after presentation
CME Text Code: 97039
In order to claim CME credit, please complete an evaluation in CloudCME for each presentation.https://knowledgeconnection.mainehealth.org/pediatrics_gr/1084/thumbnail.jp
September 24th, 2025: Advances in the Pathogenesis and Treatment of Asthma Biomarkers, Biologics, and Remission
No full texthttps://knowledgeconnection.mainehealth.org/medicine_gr/1046/thumbnail.jp
The importance of the anterior nasal spine in predicting soft tissue movement in maxillary orthognathic surgery
No full textBACKGROUND: The aim of this study was to compare and analyze the correlation between changes in maxillary hard tissue landmarks and nasolabial soft tissue points in patients with skeletal Class II and Class III malocclusion following Le Fort I osteotomy. METHODS: From 2017 to 2022, patients who underwent Le Fort I osteotomy were recruited in this retrospective study. Three hard tissue landmarks on the maxilla and twelve soft tissue landmarks on the nose and lips were selected for measurement. A Pearson correlation coefficient was used to analyze the coefficient correlations between hard- and soft-tissue changes according to the sagittal and vertical directions. Ratios with significant correlation were calculated. RESULTS: Totally 219 patients were enrolled. In skeletal Class III malocclusion, there is a widespread and significant correlation between the ANS point and A point in both the sagittal and vertical directions with the nasolabial soft tissue point. However, in skeletal Class II malocclusion, the correlations between hard- and soft-tissue points are relatively weak. Moreover, as one moves further away from the anterior nasal spine, the correlation between hard- and soft-tissue weakens. CONCLUSION: In comparison to skeletal Class II malocclusion, skeletal Class III malocclusion exhibits a stronger correlation between the movement of the ANS and A points and changes in nasolabial soft tissue landmarks, particularly in the sagittal direction. This study suggests that changes in the position of the anterior nasal spine may play a potentially significant role in predicting the post-orthognathic surgery nasolabial soft tissue morphology in patients with skeletal Class III malocclusion
Safe Patient Care in CKD: Core Curriculum 2025
No full textQuality and safety in health care have garnered scrutiny in recent decades. Complete prevention of unintended harm remains elusive. Patients with chronic kidney disease are at risk for adverse events because of the complexity of this illness and the impact of declining kidney function on choices for diagnostic studies and therapies. Nephrologists must be knowledgeable about patient safety principles and methods for evaluating harm or near harm events and be prepared to learn from investigations to make improvements. Medication safety is particularly challenging in the context of progressive kidney disease, and safety has increased in scope due to the broader choices of therapeutics for such conditions as diabetic nephropathy and anemia of chronic kidney disease. Radiologic imaging and procedural safety are also influenced by impairment of kidney function. Technological applications for patient safety are evolving and hold promise for mitigating human error and engaging patients as partners in care. In this Core Curriculum, we address essential nephrologist competency for maintaining patient safety in chronic kidney disease
Diagnostic Reasoning in Surgical Pathology
No full textRATIONALE: Diagnostic reasoning in surgical pathology is critical for accurate disease identification, particularly for rare conditions. Despite advancements in methodologies, the diagnostic lag remains significant, highlighting the need for improved reasoning skills. AIMS AND OBJECTIVES: This study examines the role of abductive reasoning in diagnostic processes within surgical pathology. A theoretical framework that integrates abduction with deduction and induction to increase diagnostic accuracy and expedite therapeutic interventions is proposed. METHODS: This paper employs a qualitative analysis of the diagnostic reasoning process, emphasizing the interconnectedness of abduction, deduction and induction. It draws on historical philosophical perspectives, particularly those of Charles S. Peirce, to explore how these reasoning types contribute to effective clinical decision-making. RESULTS: The findings underscore the importance of abductive reasoning in generating testable hypotheses, even when initial conclusions may be incorrect. The study reveals that while induction and deduction provide structure, abduction fosters creativity and broadens the scope of possible diagnoses, particularly in cases of uncertainty. CONCLUSION: The integration of abductive reasoning into surgical pathology practices is essential for improving diagnostic outcomes. By emphasizing the generative potential of abduction, this framework aims to reduce diagnostic delays and enhance clinical decision-making, ultimately benefiting patient care. The study advocates the incorporation of this reasoning approach into medical profession to better equip healthcare professionals in navigating complex diagnostic scenarios