Biology, Medicine, & Natural Product Chemistry (E-Journal - Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity)
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A Simple Method for Clearing and Staining Specimens for The Demonstration of Animal Skeleton
Get PDFTeaching skeletal system would be more attractive using real/preserved specimen compared to those using only book. The aim of the research was to develop clearing and staining method of animal skeleton specimen using Alizarin Red S-Alcian Blue as teaching aid tool. The specimen were eviscerated, fixed, stained, cleared, and keep in glycerine solution. The spesimen will increase effectiveness in elementary school science teaching and learning
Liver Profile of Atazanavir/Ritonavir in Pregnant Albino Rats
Get PDFMedication use during pregnancy is challenging due to the occurrence of maternal or fetal toxicities. Atazanavir/ritonavir (ATV/r) has hepatotoxic potential hence; use in pregnant patients living with human immunodeficiency virus may cause maternal hepatotoxicity. This study assessed the liver profile of ATV/r in pregnant albino rats. Thirty pregnant albino rats randomized into groups were orally treated daily with ATV/r (4.28/1.43 mg/kg-34.3/11.4 mg/kg) for 16 days. After treatment, the rats were weighed and sacrificed. Blood samples were collected and examined for serum biochemical parameters. Liver samples were weighed and assessed for biochemical and histological changes. Body and liver weights were normal (p>0.05) in ATV/r-treated pregnant rats when compared to control. Serum total cholesterol, triglyceride, low density lipoprotein cholesterol and blood glucose levels were significantly (p<0.01) elevated whereas high density lipoprotein cholesterol level was significantly (p<0.01) decreased in rats treated with ATV/r (34.3/11.4 mg/kg) when compared to control. Liver and serum aminotransferases, alkaline phosphatase, gamma-glutamyl transferase, lactate dehydrogenase, total bilirubin, and conjugated bilirubin levels were significantly increased in a dose-dependent fashion in rats treated with ATV/r; 8.57/2.86 mg/kg (p<0.05), 17.1/5.72 mg/kg (p<0.01) and 34.3/11.4 mg/kg (p<0.001) when compared to control. Liver superoxide dismutase, catalase, glutathione and glutathione peroxidase levels were significantly decreased whereas malondialdehyde levels were significantly increased in a dose-dependent fashion in rats treated with ATV/r; 8.57/2.86 mg/kg (p<0.05), 17.1/5.72 mg/kg (p<0.01) and 34.3/11.4 mg/kg (p<0.001) when compared to control. Necrotic hepatocytes were observed at higher doses of ATV/r. ATV/r may not be hepatotoxic in pregnant women living with HIV at the clinical dose
The Effects of Wet Cupping Therapy in Blood Pressure, Glucose, Uric Acid and Total Cholesterol Levels
Get PDFWet cupping therapy is a simple, cheap, and effective alternative medical treatment. In China wet cupping therapy become a formal treatment in the hospital. 14 centuries ago Prophet Muhammad implemented wet cupping therapy or hejamah as a curing treatment and become sunnah for muslim. Today in a modern world, many studies proved the advantages of wet cupping therapy, which is a sunnah since 14 centuries ago. The aims of this study were to measure the effects of wet cupping therapy treatment on blood pressure, blood glucose, uric acid, and total cholesterol level. 21 participants were treated with hejamah/wet cupping, blood pressure and blood samples were collected from all the participants one week before and one week after hejamah. Blood pressure, either systolic or diastolic was significantly decreased following therapy (p||0.05). uric acid and total cholesterol level was also significantly decreased following therapy (p|<|0.05). With only just one time treatment, hejamah had a significant effects on blood pressure, uric acid and total cholesterol level, that is proved the advantages of hejamah
Statistical Analysis of Habbatussauda’s Benefits for Health (Blood Pressure, Glucose and Uric Acid)
Get PDFHabbatussauda is one of the traditional medicine existed since a long time ago and this is one of the drugs that recommended by the Prophet Muhammad. Habbatussauda’s benefits have been studied extensively in the healthcare. Habbatussauda has also been widely used to cure various diseases. This study revealed the benefits of Habbatussauda in lowering blood pressure, glucose and uric acid levels in 20 respondents that given Habbatussauda for 2 weeks. The blood pressure, glucose and uric acid levels were measured before and after consuming Habbatussauda. Blood pressure, glucose, and uric acid levels in the body will decrease after consuming Habbatussauda that shown in the statistical analysis of the obtained data
Mathematical Model of Cervical Cancer Treatment Using Chemotherapy Drug
Get PDFCervical cancer is a malignant disease that causes problems in women's health, especially in developing countries such as Indonesia. Cervical cancer cells will develop quickly, uncontrollably, and will continue to divide and then infiltrate the surrounding tissue and continue to spread to connective tissue, blood, and attack important organs and spinal nerves. The aim of the research is to study the mathematical model of cervical cancer by chemotherapy treatment. The results of this study are that cervical cancer treatment using chemotherapy is effective enough to kill abnormal cells such as infected cells, pre-cancerous cells and cancer cells, although there are side effects, namely the killing of normal cells due to chemotherapy drugs
Echinoderms Diversity and Abundance in Gunung Kidul Beach Yogyakarta
Get PDFEchinoderms are one of marine invertebrate animals that have an important role, as a recycle of nutrients in the functioning of ecosystems. Echinoderms usually appear in the intertidal zone of the coast. The existence of echinoderms in the intertidal zone is affected by external and internal factors. This study aims to determine the level of abundance and diversity of Echinoderms in the intertidal zone in the Krakal and Drini coastal areas, Gunung Kidul, Yogyakarta. Data were collected using transect method. The main transect along 50 meters was divided into 5 sampling points, and the distance between sampling points was 10 meters. After that, each point was taken for 3 observation plots with an area of 1x1 meters and the distance between plots is 5 meters. The results showed that, the diversity index on the krakal coast had a higher value (0.139) when compared to the Drini coast (0.129). Calculation of echinonderm abundance index shows that the Drini beach location has a high abundance value when compared to the abundance value at the Krakal beach loc ation. The parameter measurement results can be seen that both the pH and temperature parameters on both the Krakal and Drini coast have values that correspond to the optimum parameter in the waters
Digital Anthropometer Development for Improving the Measurement Quality of Human Body Dimensions
Get PDFDigital information technology has become the nerve of information for industry-based companies. However, there are still data or information that retrieved manually, one of them is measurement of the human body dimension. The problem is seemed solved by invention of digital anthropometer application. Yet, the application requires a further improvement especially in its accuracy and user interface. The improvement of accuracy quality of its measurement uses the capability process analysis method. As a result, the current Cp and Cpk is 0.26 and -0.209 while in the developed application is 2.56 and 1.218. Thus, the developed application is stated that quality of measurement increases to meet the criteria of good process capability. The user interface is improved based on the user voices. Data storage databases and percentile calculation in the application was added as one on the significant user-interface improvement
