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Cognitive, psychological and physical functioning in post COVID-19 patients with different levels of fatigue: a descriptive abstract
No full textBackground: Recent studies have shown that a growing number of mild COVID-19 cases experience prolonged symptoms, reporting a range of disabling symptoms such as fatigue, shortness of breath, cognitive impairment, memory loss, and mental health and employment issues up to months following the infection. This has recently been accounted for by the World Health Organization, which has defined post COVID-19 as a condition that usually occurs three months from the onset of COVID-19 with symptoms that last for at least 2 months and cannot be explained by an alternative diagnosis. A data-driven identification of subgroups of post COVID-19 could help in referring this clinically heterogeneous group of patients to the appropriate care. However, most of the evidence has been obtained through self-reported and retrospective surveys, lacking in-person monitoring and assessment of cognitive, physical, and …Voor extra info [email protected]
The political economy of accountability: Philanthropy's 'double dispossession' of racial justice organizations under racial capitalism
No full textPrompted by the Black Lives Matter movement, and COVID-19's deepening of inequalities, philanthropic foundations are increasingly claiming racial justice as a core part of their mission and strategy. This study uses a racial capitalism lens to examine racial justice organizations' (RJOs) accountability relations towards the philanthropies that fund them. Drawing on interviews with leaders of Canadian RJOs, we unveil how the racial partitioning of leaders, fantasy and partners in these relations materially and symbolically dispossesses RJOs and the communities they represent. Our study complements the extant literature, which focuses on the depoliticization and co-optation effects of RJO-philanthropy accountability relations. Instead, we show how these accountability relations enforce 'double dispossession', thereby reproducing the racial capitalist political economy on which philanthropy is predicated. Our analysis indicates that philanthropy for racial justice, as it is currently practised, is impossible. We further identify the conditions under which it could become feasible.Thank you to Ajnesh Prasad and the three anonymous reviewers for their thoughtful, generous and encouraging input
Motor difficulties in children with neurodevelopmental conditions: a report from a cross-national study in Belgian and Italian children
No full textMotor behavior alterations are common in neurodevelopmental disorders (NDDs), including autism, developmental coordination disorder (DCD), and attention deficit hyperactivity disorder (ADHD), but the extent of motor impairment remains unclear. In autism and ADHD, motor difficulties may be linked to co-occurring DCD, which often goes unrecognized. We aimed to map the prevalence of DCD in autism and ADHD, and to explore motor skill difficulties using the Movement Assessment Battery for Children-2 (MABC-2), by comparing children with typical motor development (TMD) with those who have NDDs, and by identifying specific profiles among NDDs. A combined sample of participants (n = 215), including autistic children with(out) intellectual disability (ID) and children with ADHD, DCD, and TMD, performed the MABC-2. Depending on co-occurring DCD/ID, subgroups were composed: autism-only (n = 17), autism + ID (n = 17), autism + DCD (n = 40), ADHD-only (n = 14), ADHD + DCD (n = 12), DCD (n = 25), and TMD (n = 59). MABC-2 differences between TMD/NDDs (Mann-Whitney U test) and among NDDs (Kruskal-Wallis test) were assessed. DCD occurred in 70.2% of the autistic children without ID and in 46.2% of those with ADHD. Children with NDDs performed significantly worse than the TMD (p < 0.001). Manual dexterity skills, aiming and catching, and balance were significantly different across the NDD subgroups (p <= 0.001). Particularly children with ( +)DCD and autism + ID performed worse on manual dexterity skills. Children with ( +)DCD were outperformed on aiming and catching. All subgroups, except the ADHD-only group, performed poorly on balance. Conclusion: Distinct motor difficulties were identified across various NDDs. Children with co-occurring ID or DCD exhibit unique challenges, stressing the importance of motor profile subgrouping. What Is Known: center dot Despite the common occurrence of motor behavior in neurodevelopmental disorders, the extent of motor impairment remains unclear. center dot Motor difficulties in autism and ADHD may be linked to co-occurring DCD, which often goes unrecognized. What Is New: center dot DCD occurred in 70% of the autistic children without ID and in 46% of those with ADHD. center dot Children with co-occurring ID or DCD exhibit unique challenges, stressing the importance of motor profile subgrouping.This work was supported by grants from the Italian Ministry of Health (Ricerca Finalizzata GR2011-02348929; Ricerca Corrente 2024-2025) and from FWO (grant number: 43498 (1117621N), 2020
Solution based synthesis of inorganic materials for (photo)electrocatalysis towards water splitting and CO2 reduction
No full textDESINe team members
Prof. dr. Marlies Van Bael
dr. ir. Bjorn Joos
dr. Ken Elen
ELCAT team members
Prof. dr. Ing. Tom Breugelmans
dr. ir. Nick Daems
EE group
Prof. dr. Momo Safar
Woonwensen en -noden van de diverse ouderenbevolking. Het belang van divers-sensitief ontwerp.
No full textDe meeste woningen waar ouderen in wonen zijn niet leeftijdsvriendelijk ontworpen. Toch willen de meeste ouderen in Vlaanderen liefst zo lang mogelijk thuis blijven wonen. Daarnaast wordt de ouderenbevolking steeds diverser, maar blijft kennis hierover beperkt. Het onderzoek beschreven in dit artikel beoogt om nieuwe inzichten te verwerven in het wonen, welbevinden en thuisgevoel van ouderen met een migratieachtergrond, zodat deze kennis vertaald kan worden naar woning-en buurtontwerp. De aanpak van deze vertaalslag staat centraal in deze bijdrage
How to improve functional outcome of inflatable penile implant surgery? a narrative review
No full textThe implantation of a three-piece inflatable penile prosthesis (IPP) has been shown to be a safe and successful treatment with a high satisfaction rate among individuals with erectile dysfunction. This narrative review aims to explore ways to improve the functional outcomes of IPP implantation. We conducted an English-language narrative review using all relevant articles sourced from PubMed. Over the years, modifications in IPP surgery have focused on increasing the longevity of prostheses and improving functional outcomes. These modifications include advancements in surgical methods, implant types, intracorporeal tubing length, the use of rear tip extenders, and reservoir placement. IPP implantation continues to significantly improve quality of life, making it essential for surgeons to stay updated on the latest developments and research to ensure the best outcomes for their patients. Optimal functional outcomes are achieved by an experienced surgical team and the use of a safe, rapid, minimally invasive surgical technique with the latest technology and equipment.Open access funding provided by the Scientific and Technological Research Council of Türkiye (TÜBİTAK)
Pharmaco-Invasive Strategy With Half-Dose Tenecteplase in Patients With STEMI: Prespecified Pooled Analysis of Patients Aged ≥75 Years in STREAM-1 and 2
No full textBACKGROUND: In STREAM-1 (Strategic Reperfusion Early After Myocardial Infarction), excess intracranial hemorrhage occurred in patients aged >= 75 years receiving full-dose tenecteplase as part of a pharmaco-invasive strategy, whereas no further intracranial hemorrhage occurred after halving the tenecteplase dose. In STREAM-2 (Second Strategic Reperfusion Early After Myocardial Infarction), half-dose tenecteplase was an effective and safe pharmaco-invasive strategy in older patients with ST-segment-elevation myocardial infarction presenting within = 75 years. METHODS: We pooled data sets in patients aged >= 75 years from STREAM-1 and STREAM-2 receiving a pharmaco-invasive strategy versus primary PCI. Resolution of ST-segment-elevation after fibrinolysis and angiography was assessed, as was the relative risk of the primary composite of 30-day all-cause death, myocardial infarction, heart failure, and shock, along with bleeding. RESULTS: A total of 390 patients were included: 42 patients were randomized to full-dose pharmaco-invasive treatment, 205 patients to half-dose pharmaco-invasive treatment, and 143 patients to primary PCI. Half-dose versus full-dose pharmaco-invasive treatment resulted in similar proportions of patients achieving >= 50% ST-segment resolution posttenecteplase (63.2% versus 62.6%), with reduced intracranial hemorrhage (7.1% versus 0%, respectively). Half-dose pharmaco-invasive treatment and primary PCI also had similar proportions of patients with >= 50% ST-segment resolution postangiography (77.9% versus 72.4%; P=0.277) and comparable composite end points (23.4% versus 28.0%; relative risk, 0.90 [95% CI, 0.62-1.30]; P=0.567) without occurrence of intracranial hemorrhage. CONCLUSIONS: Comparable efficacy exists between half- and full-dose tenecteplase pharmaco-invasive treatments with improved safety in patients with ST-segment-elevation myocardial infarction aged >= 75 years. Half-dose pharmaco-invasive therapy is a legitimate therapeutic option for elderly patients with ST-segment-elevation myocardial infarction unable to access timely primary PCI. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT00623623. URL: https://www.clinicaltrials.gov; Unique identifier: NCT02777580.Department of Research and Development of KU Leuven, Life Scienc
Verbintenissenrecht 2023-2024
No full textDeze studentencursus verbintenissenrecht is voor de beginnende studenten rechtsgeleerdheid een eerste kennismaking met het Belgische verbintenissenrecht. Zij dient als leidraad voor de hoorcolleges en onderwijsgroepen van dit opleidingsonderdeel in de eerste fase van de bacheloropleiding rechten aan de UHasselt (Verbintenissenrecht 1875). Het doel van die opleiding is om een grondige basiskennis aan te reiken. De bachelorstudenten maken zich de taal en de methode van de rechtsdiscipline eigen. Ook in deze studentencursus komen daarom de beginselen, het ‘abc’ van het verbintenissenrecht aan bod. De lezer ervan leert op welke fundamenten het verbintenissenrecht steunt. De omvang van de studentencursus is daardoor eerder beknopt. Zonder zich te verliezen in al te veel details, schetst zij de grote lijnen. Zo’n kennis van en inzicht in de grote lijnen is belangrijk. Wie deze beheerst, heeft geen – alleszins minder – moeite om daarna met behulp van uitgebreidere handboeken verbintenissenrecht de overstap te maken naar verdieping en de details. Een goed jurist weet hoe de beginselen zich tot elkaar verhouden en kan uit hun samenspel een zorgvuldig afgewogen en rechtvaardig antwoord op elke rechtsvraag laten voortvloeien. Hoewel die basiskennis en -kunde noodzakelijk zijn, volstaat het niet dat de cursus louter theoretisch zou blijven. Studenten moeten ook leren hoe om te gaan met specifieke casussen. Deze studentencursus biedt daarom voorbeelden die de leerstof met praktische toepassingen illustreren. Daarnaast vormt deze studentencursus één geheel met de hoorcolleges en onderwijsgroepen. Het is vooral tijdens die contactmomenten dat de studenten de theorie samen met het onderwijsteam tot leven doen komen. Het onderwijsteam van de KU Leuven dat verbintenissenrecht doceert aan de UHasselt, bestaat uit enkele bijzonder bekwame en gemotiveerde tutoren, die samen met ons vorm hebben gegeven aan deze tweede – verbeterde – versie van de studentencursus. We danken mr. Trees Ceustermans, mr. Jirte Forier, dra. Michelle Schouteden, drs. Lukas Van Roy, dra. Fleur Vanswijgenhoven en mr. Dorien Vervoort van harte voor al hun steekhoudende bedenkingen, opmerkingen en aanvullingen ten aanzien van de vorige versie van de studentencursus. Ilse Samoy en Christopher Borucki, januari 202
Effectiveness of Mobile Health-Based Gamification Interventions for Improving Physical Activity in Individuals With Cardiovascular Diseases: Systematic Review and Meta-Analysis of Randomized Controlled Trials
No full textBackground: Gamification refers to using game design elements in nongamecontexts. Promoting physical activity (PA) through gamification is a novel and promising avenue for improving lifestyles and mitigating the advancement of cardiovascular diseases (CVDs). However, evidence of its effectiveness remains mixed. Objective: This systematic review and meta-analysis aimed to evaluate the efficacy of gamification interventions in promoting PA during short-term and follow-up periods in individuals with CVDs and to explore the most effective game design elements. Methods: A comprehensive search of 7 electronic databases was conducted for randomized controlled trials published in English from January 1, 2010, to February 3, 2024. Eligible studies used mobile health-based gamification interventions to promote PA or reduce sedentary behavior in individuals with CVDs. In total, 2 independent reviewers screened the retrieved records, extracted data, and evaluated the risk of bias using the RoB 2 tool. Discrepancieswere resolved by a third reviewer. Meta-analyses were performed using a random-effects model with the Sidik-Jonkman method adjusted by the Knapp-Hartung method. Sensitivity analysis and influence analysis examined the robustness of results, while prediction intervals indicated heterogeneity. A meta-regression using a multimodel inference approach explored the most important game design elements. Statistical analyses were conducted usingR (version 4.3.2; R Foundation for Statistical Computing). Results: In total, 6 randomized controlled trials were included. Meta-analysis of 5 studies revealed a small effect of gamification interventions on short-term PA (after sensitivity analysis: Hedges g =0.32, 95% CI 0.19-0.45, 95% prediction interval [PI] 0.02-0.62). Meta-analysis of 3 studies found the maintenance effect (measured with follow-up averaging 2.5 months after the end of the intervention) was small (Hedges g =0.20, 95% CI 0.12-0.29, 95% PI -0.01 to 0.41). A meta-analysis of 3 studies found participants taking 696.96 more steps per day than the control group (95% CI 327.80 to 1066.12, 95% PI -121.39 to 1515.31). "Feedback" was the most important game design element, followed by "Avatar." Conclusions:This meta-analysis demonstrates that gamification interventions effectively promote PA in individuals with CVD, with effects persisting beyond the intervention period, indicating they are not merely novel effects caused by the game nature of gamification. The 95% PI suggests that implementing gamification interventions in similar populations in the future will lead to actual effects in promoting PA in the vast majority of cases. However, the limited number of included studies underscores the urgent need for more high-quality research in this emerging field.This work was supported by the National Key Research and Development Plan Project Sub-topic of China (grant number 2022YFC3601305) and the China Scholarship Council scholarship program (grant number 202306170197)
Eye-tracking: Understanding the WHY behind shopping behavior
No full textThis paper discusses a mixed method study in which we combine eye-tracking with semi-structured in-depth interviews, conducted at two similar stores of a retailer in the cosmetics sector. With this study the retailer wanted to investigate, on the one hand, how customers navigate and move around the store and, on the other hand, what they think of the design and experience of the two stores. Through this qualitative research method, you get a very rich set of information that mainly provides insights into the "why" behind shopping behavior. The results concerning shopping behavior indicate that in this store customers mainly navigate at eye level through product recognition. On the evaluation of the shopping experience, customers fairly unanimously recognize which elements are positive and which are more likely to be disruptive in a store design