Kalamazoo College

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    My 100 hours working at Lawndale Dental

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    8 p.For my senior experiential SIP, I did 100 hours at the Lawndale Dental clinic located in the city of Chicago. What made working at this office so remarkable was the environment and staff who supported me along the way

    Using Point Arrays to Characterize the Structure of Drug-Bound Hepatitis B Virus Capsids

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    1 Broadside. 48"W x 36"HUse point arrays to examine the structural changes in capsid structures induced by drug binding.Kalamazoo College. Department of Biology. Diebold Symposium, 202

    Acting(Directing/Writing/Designing) Shakespeare

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    1 Broadside. 48"W x 36"HResearch and reread my favorite Shakespeare plays. Cut McKellen’s “Acting Shakespeare” down from full-length to one act. Find excerpts from Shakespeare's works to replace sections in the original script. Rewrite the script to fit my narrative. Rehearse the new play I had created. Perform the show. Complete SIP documentation.Kalamazoo College. Department of Biology. Diebold Symposium, 202

    Finding Aid for Eduard Avis SIP Research Materials

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    3 p.This finding aid describes the materials related to Eduard Avis's SIP on the 1968-69 BSO protests. The records date from 1988 to 1989

    Investigating the Role of SIRT1 Substrates in Regulating Replication Origins in Cancer Cells

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    21 p.Sirtuin 1 (SIRT1) is an NAD+ dependent protein deacetylase that acts as a metabolic sensor in normal and cancer cells. Previous findings from our lab show that SIRT1 binds to replication origins and prevents excessive origin activation; however, SIRT1’s substrates on replicating origins and their function in regulating origin activity are not yet fully understood. Our studies focus on identifying protein targets for SIRT1 on replicating DNA using a novel technique based on the isolation of proteins on nascent DNA (iPOND) . We perform iPOND on SIRT1 proficient and deficient HCT116 cells (colon cancer patient) during normal proliferation and after treatment with aphidicolin (a known inducer of excessive replication). Under these conditions, we expect that SIRT1’s target, which is eliminated from replicating DNA by SIRT1 during normal growth, will be enriched in cells without SIRT1 or after aphidicolin treatment. Using chromatin immunoprecipitation and quantitative PCR, we will quantify the abundance/presence of selected targets on replication origins. This will aid in pinpointing the mechanism by which SIRT1 and specific substrates suppress the initiation of DNA replication from replication origins, thus preventing excessive replication to insure genomic stability

    Kalamazoo College Academic Catalogue, 2022-2023

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    486 p.Policies -- Curriculum -- Academic Programs -- Directories

    The Effects of Elevation on Pseudacris maculata Presence in Rocky Mountain National Park

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    1 Broadside. 48"W x 36"HBoreal chorus frog populations are declining rapidly due to habitat loss, disease, and invasive species, which will be compounded by climate change. The changing environment of the planet has led to an increasing variability in temperature and precipitation, which has caused a negative impact on individual amphibian metamorphosis and growth. Elevation is an environmental variable that has been studied widely, however it can be hard to tease apart the effects of elevation in comparison to climate change. Pseudacris maculata populations are distributed at various elevations, but it is unclear if this is due to elevation preference or in response to climate change. This study aims to investigate if there is a connection between elevation and amphibian presence, specifically proposing that increasing elevation would have a negative effect on the presence of P. maculata in Rocky Mountain National Park. This research was carried out using double visual encounter surveys at various sites in the park with elevation and presence recorded at each site. The binomial linear regression analysis run showed no significant results. Elevation did not have an impact on P. maculata presence, and although there was a negative correlation between P. maculata and elevation, the result was not statistically significant. Future climate change consequences indicate a continued rapid population decline, with high mortality and stunted growth in P. maculata.Kalamazoo College. Department of Biology. Diebold Symposium, 202

    Graphic Design & User Experience Research Internships

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    1 broadside. 48"W x 36"HComplete a UX/ UI project Learn in-demand design tools. Expand my knowledge of design. Update professional materials and apply to jobs. User Experience Design and User Interface Project User research through surveys & focus groups. Synthesizing data and identifying pain points. Wireframing, prototyping, and designing app as solution. Present design to campus community. Usability Testing for Upjohn Library Center Observing users interact with interface. Gathering insights from data. Improving interface by changing design.Kalamazoo College. Department of Psychology. VanLiere Symposium, 202

    Only (a) God Can Save Us Now : Heidegger, Modernity, and Poetry

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    59 p.Heidegger, in a 1966 interview with German magazine Der Spiegel (published posthumously), spoke about his relationship to National Socialism and how it broadly was informed by his concerns regarding technology. In the interview, Heidegger utters a now-famous phrase, which I have taken as the title for this paper: “Only a god can save us now.” Contextualizing this phrase within the Nietzsche-Hölderlin discourse, its initial tonal despondence is revealed as a call to action for thinkers and poets. “Only a god can save us. The only possibility available to us is that by thinking and poetizing we prepare a readiness for the appearance of a god, or for the absence of a god in [our] decline, insofar as in view of the absent god we are in a state of decline…we cannot bring him forth by our thinking. At best we can awaken a readiness to wait…” In the same interview with Der Spiegel, Heidegger makes this comment, within which lies the entire scope of this paper: “Everything is functioning. That is precisely what is awesome, that everything functions, that the functioning propels Everything more and more toward further functioning, and that technicity increasingly dislodges man, and uproots him from the earth. I don't know if you were shocked, but [certainly] I was shocked when a short time ago I saw the pictures of the earth taken from the moon. We do not need atomic bombs at all [to uproot us] — the uprooting of man is already here. All our relationships have become merely technical ones. It is no longer u on an earth that man lives today. Recently I had a long dialogue in Provence with Réné Char— a poet and resistance fighter, as you know. In Provence now, launch pads are being built and the countryside laid waste in unimaginable fashion. That poet, who certainly is open to no suspicion of sentimentality or of glorifying the idyllic, said to me that the uprooting of man that is now taking place is the end of everything human], unless thinking and poetizing once again regain [their] nonviolent power.

    Art as We Know It

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    28 minutes, MP4 format videoIn an original video documentary, three student artists share their creative process and reflect on the art school experience during the Covid-19 Pandemic. Kalamazoo College performance artist Rebecca Chan, Western Michigan University guitarist Jack Fergusson, and Kendall College 3-D visual artist Grace Muchmore address the questions "how did your relationship with art change?" and "how did you continue to stay connected with the community?" during the past two years

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