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    4292 research outputs found

    Inventory of Martin Marietta Documents

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    The Martin Marietta Documents consist primarily of reports. Subject matter is diverse and includes 1969 Shuttle Phase A reports as well as 1978 Teleoperator System material. They run from 1967 through 1988, although the bulk of the material falls between 1975 and 1978. The documents are arranged in chronological order

    Computational Analysis of Various Reactions Between Hydroxyl Radicals and Organic Mercury Species

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    The interactions between hydroxy radicals and both dimethylmercury and methylmercury hydroxide have been studied using ab-initio methods. The density functional theory (DFT) method M06-2X was used to optimize the structures of the stationary points in each reaction channel. The single point energies were determined using coupled-cluster theory (CCSD(T)). For the reaction with dimethylmercury there are three possible channels, with the favored product as methylmercury hydroxide with the smallest energy barrier of 7.3 kcal mol-1 (k(TST)=1.23x10-12 cm3 molecule-1 s-1). For the reaction between hydroxyl radical and methylmercury hydroxide there are six possible channels with the most probable channel being a hydrogen abstraction to form MeHgO radical. This channel has the lowest energy barrier of 2.5 kcal mol-1 with a rate constant of 3.87x10-9 cm3 molecule-1 s 1. Based on these results, dimethylmercury will undergo demethylation due to hydroxyl radicals whereas methylmercury hydroxide will not

    Inventory of Shuttle Photographs

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    The Shuttle Photographs are made up of 8x10 photographs and viewgraphs and coverthe years 1969-1983. NASA-generated photos and viewgraphs are arrangedchronologically by year and numerically within each year. Rockwell-generated photosand miscellaneous photos (unnumbered) are filed at the end of each year. Miscellaneous photos that are unnumbered and undated are filed at the end of the run. The collection contains only Shuttle-related photographs and viewgraphs and, therefore, numerical runs are incomplete

    Systematic review and meta-analysis of Pimavanserin and Volinanserin in Schizophrena treatment

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    Schizophrenia is a severe mental disorder that affects 1% of the population. Despite its low prevalence, it is ranked among the top fifteen leading causes of disability worldwide. Antipsychotics targeting serotonergic receptors, specifically 5-HT2A receptors, are being developed for schizophrenia treatment and continue to show promise. Pimavanserin and Volinanserin are two such atypical antipsychotics that are highly selective towards the 5-HT2A receptor. In this study, we performed a systematic review and meta-analysis of Volinanserin (MDL-100907) and Pimavanserin (ACP-103) to evaluate the effectiveness of these drugs in the treatment of schizophrenia. A literature search was performed using Pub-Med, ClinicalTrials.gov, and Cochrane databases. Our search strategy consisted of the following strings: Pimavanserin or ACP-103 and Volinanserin or MDL-100907 and Schizophrenia or Schizophrenia spectrum. Based on comparable outcomes of measurement (i.e., PANSS, SGI, KSS, DAI-10), Pimavanserin is a safe adjunctive treatment. However, there is not enough data to conclude efficacy. These results provide additional support for 5-HT2A as a key component for the treatment of schizophrenia. Continued research is needed on the efficacy of Pimavanserin, Volinanserin, and other drugs that target 5-HT2A receptors in the treatment of schizophrenia

    The relationship between faculty diversity and graduation transfer and drop out rates in public community colleges

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    Previous research has found that overall graduation rates for underrepresented minority (URM) students of all races and ethnicities were positively affected by increased diversity of their faculty. Using 2017 archival IPEDS data from 120 public community colleges this mixed-methods research study replicated and expanded previous research of Stout, Archie, Cross, and Carman (2018) by calculating an institutional Diversity Score as a common measure of diversity and ranking the community colleges by their overall level of race/ethnic and gender variance. The findings suggest that there was a significant strong positive relationship between graduation, transfer, and drop out rates for URM students of all race/ethnic catagories when there are increases in faculty diversity. There were no significant findings regarding the relationship of faculty gender to student graduation, transfer, or drop out rates. In the qualitative component of this study six community college presidents and 15 former community college students were interviewed to understand their perceptions regarding the relationship of faculty race, ethnic, and gender diversity and student success. These themes were: (a) changes in our communities drive the need for change in our colleges, (b) inclusion is a process of accommodation, and (c) mentoring and role modeling are critical. Analysis of student responses revealed two themes: (a) individual connections are important, and (b) female teachers matter to female students. Findings suggest that positive interactions with URM faculty can provide URM students with a role model that increases their sense of welcome, acceptance, and motivation to succeed. When students are exposed to a diverse faculty they feel more comfortable and have better outcomes. Increasing faculty diversity can be an important step for improving an environment for student success

    Inventory of Lunney Documents

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    This subseries consists of documents collected by Glynn S. Lunney between 1978 and 1980. At that time he was manager of the Shuttle Payload Integration and Development Program Office, which was later renamed the Space Transportation Systems Operations Office. His documents consist primarily of copies of presentation charts from various meetings, briefings and reviews. The folders have been maintained in the order they were received and the folders are organized by date. The collection consists of three linear feet of documents

    Inventory of McDonnell Douglas Documents

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    These documents consist of McDonnell Douglas Shuttle-related reports generated between the years 1965 and 1982. The bulk of the documentation consists of Phase B and Phase B Extension reports and the Phase C/D proposal. The documents are organized in chronological order, ending with undated documents

    A Framework for Improving Performance Testing in Agile Software Development

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    The subdiscipline of software quality assurance concerned with non-functional requirements (NFRs) and hardware metrics is known as performance testing. Conducting effective performance testing is complicated, time consuming, and expensive. These attributes put performance testing at odds with agile software development methodologies, which incrementally build software systems in quick cycles while being supported by exhaustive unit and integration test coverage. Due to a variety of challenges, performance testing often cannot keep up with an agile release cadence, and there is a growing body of research that catalogues and describes these challenges and proposes solutions to some of them. This study presents a software testing framework which implements several of the proposed solutions. The framework, called Lulu Performance Test (LPT), aims to confront many of the challenges noted in recent research, with the goal of making effective performance testing more palatable to agile software development methodologies

    Inventory of STS-9 Mission Documents

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    This subseries consists of air to ground transcripts, press briefings, press kits, FRR, Flight Directors Log and other material related to the STS-9 mission. Documents are arranged chronologically by folder and include microfiche as well as hard copy. Dates range from 1979 to 1984

    Inventory of United Technologies Center Documents

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    This subseries consists of documents produced by the United Technologies Center. There is one 1972 document on solid rocket motors. The remaining documents are dated 1982-83 and deal primarily with the Extravehicular Mobility Unit (EMU) used on STS-5

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