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Deep Neural Network & Dynamic Functional Connectivity Analysis of Functional MRI Data
DEEP NEURAL NETWORK & DYNAMIC FUNCTIONAL CONNECTIVITY ANALYSIS OF FUNCTIONAL MRI DATA
Amaresh Kumar Mishra
University of Houston-Clear Lake, 2022
Thesis Chair: Unal ‘Zak’ Sakoglu, PhD
This thesis work presents a dynamic functional connectivity (DFC)-based classification analysis of an already collected and completely de-identified functional magnetic resonance imaging (fMRI) dataset from two groups, veterans with Gulf War Illness (GWI), vs matched controls. Neuroimaging or brain imaging is the use of various techniques to either directly or indirectly image the structure, function, or pharmacology of the nervous system. fMRI is a neuroimaging technique which is used to measure brain activity by detecting changes associated with blood oxygenation level dependence (BOLD), which is an indirect measure of neural activity, and it helps obtain three spatial dimensional (3D) brain activation maps associated with certain stimulus and/or a task, depending on the experiments performed during the fMRI scan.
Whole-brain resting-state fMRI (rsfMRI) data which were scanned from 23 GWI veterans (mean age 49.4) and 30 normal control (NC) veterans (mean age 49.8) were used for analyses. A computational method using DFC features, deep learning, and machine learning techniques were used to correctly classify GWI vs NC. Results show that, support vector machine (SVM) -based machine learning technique, combined with simple t-test method for feature extraction (using the DFC), performed better than convolutional neural network (CNN) deep learning method, in terms of classification accuracy (upwards of 98% accuracy for the former vs. upwards of 60% accuracy for the latter)
Inventory of Thermal Protection System (TPS) Documents
This subseries consists of documents collected on the Shuttle thermal protection system. They are organized alphabetically by folder and range from 1960 to 1983. This is a preliminary inventory
Inventory of Voss Documents
The documents in this subseries were given to us by Robert G. Voss of the NSTS Program Control Office. They consist of reports, presentations and papers regarding Pre-Phase A Shuttle studies, ILRV, and Phase B contract information. The dates range from 1967 through 1974 and, except for the pre-Phase A documents, they are arranged chronologically
Inventory of STS-51-G Mission Documents
This subseries consists of documents related to the Shuttle STS-51-G mission. The material includes Flight Requirements Documents, Cargo System Manuals, Mission Reports, and Press Information. The material is arranged in chronological order and are dated from 1984 to 198
Chrome, Neon, and Cyborgs: The Cyberpunk Genre in the 1980’s United States
This project was done to prove the viability of fiction as a crucial source of historical artifacts by focusing on the genre of cyberpunk, a genre localized in the 1980s United States, to show how the cultural anxieties Americans had about the shifting trends in media, military, and economic matters birthed that genre. Research for this topic utilized three different fiction mediums from cyberpunk (film, novel, and tabletop roleplaying game) and combined each selected source from these mediums with primary documents drawn from 1980s news outlets, government addresses and press conferences, economic data from places such as the Federal Reserve, and interviews and memoirs from historical actors. This was all kept in context given by secondary source monographs and articles that cover the various topics of the 1980s that caused the anxieties that birthed cyberpunk as a unique and historically localized genre. The conclusion of this work divorced cyberpunk from post-1980s stories that claim that genre. In addition, the conclusion held that fiction has a critical place as historical artifact needed to gain as complete a record of humanity as possible, and that cyberpunk is crucial to understanding 1980s America in particular.
Finding Aid for the Human Space Flight Reference Collection (HSF-2)
The Human Space Flight Reference Collection contains brochures, pamphlets, educational handouts, programs, flyers, guides, articles, and miscellaneous materials, collected by the University of Houston-Clear Lake Archives and Special Collections to document NASA’s Johnson Space Center in Houston, Texas. The materials were originally organized as the “NASA/JSC Vertical Subject Files” beginning in 2001, when the Archives began collecting materials pertaining to the local Johnson Space Center (JSC) facility. The materials generally represent published and printed materials intended for the public, including educators and the media, highlighting NASA and space exploration programs. Many of the pieces of ephemera who produced as public relations materials by JSC’s Public Affairs Office. Many of the items were published by NASA, JSC, and various internal departments, as well as other NASA facilities outside of Texas. The collection also includes magazine and newspaper publications, organizational event materials, and space exploration educational and cultural content, produced and distributed by non-NASA entities
Finding Aid for the Robert Heselmeyer Papers (HSF-56)
The Robert Heselmeyer Papers contains reports, memos, notebooks, technical manuals and handbooks, dictionaries, checklists, guides, flight schedules, technical requirements records, meeting logs, activity reports, plans, charts, and other materials, documenting the entire career of Robert Heselmeyer at NASA’s Johnson Space Center (JSC) from 1966 to 2004. He worked as an engineer on the Project Apollo missions as a Lunar Module Flight Controller, specifically as the Vehicle Systems Engineer for the Telemetry, Electrical, and (EVA) Mobility Unit (or TELMU). Heselmeyer served as a Biomedical Experiments Flight Controller for the medical experiments on the Skylab Program. He worked from the mid-1970s through the 1980s in Space Shuttle flight support positions within the National Space Transportation System (NSTS) Program Office. The largest and most significant set of materials in the collection are original manuals, handbooks, and schedules from Heselmeyer’s role with the Apollo 11 and Apollo 13 missions. All of the materials in the collection pertaining to specific mission or projects to which Heselmeyer was assigned were actually used during his work on those various assignments at Johnson Space Center
Finding Aid to the Kenneth R. Goodwin Papers
The Kenneth R. Goodwin is composed of internal NASA and MIT Instrumentation Laboratory (now Charles Stark Draper Laboratory), memorandums, space guidance analysis memos, and research and procedure booklets for the operations of Project Apollo and space flight missions, used and kept by Kenneth R. Goodwin between 1965-1972. Goodwin used the materials while working as an Apollo Program test engineer executing functional tests in the hardware-software area of the optical/radar subsystems for the Apollo vehicles, including while assigned to the Lab’s Field Site Office at the NASA Manned Spacecraft Center (MSC). Included in the collection are the memorandums of Howard W. “Bill” Tindall, Jr. between 1966-1970, known as Tindallgrams, documenting technical decisions for all unmanned and manned flights through Apollo 13. A large portion of the collection are the MIT Space Guidance Analysis Memos which include research topics spanning between 1965-1968 from multiple engineers that guided space travel for the Apollo Missions, including research on position and velocity uncertainties for lunar missions. The MIT Apollo Guidance, Navigation, and Control booklets cover a majority amount of the collection and are limited published books spanning between 1965-1972, they were used and kept by Goodwin during his time at NASA, covering topics such as a system operations plan for manned LM earth orbital and lunar missions using program luminary IA
Predicting Adherence to Health Behaviors: Developing a Screening Questionnaire to Facilitate Engagement in Diet and Physical Exercise
High rates of individuals are diagnosed with one or more chronic illnesses, such as heart disease, cancer, and diabetes. The prevalence of chronic illness has led to increased healthcare costs and spending, increased co-morbidities of mental and medical health problems, and increased risk of mortality. Moreover, individuals may also lack engagement in health-promoting behaviors (i.e., physical activity, weight management) and adherence to behavioral recommendations. Due to limited research on predictors of adherence, as well as a lack of objective measures to assess adherence to behavioral recommendations, the use of a brief screening questionnaire may be beneficial to healthcare providers as they seek to provide treatment and optimize patient adherence. Therefore, the aim of this study is to predict adherence to health behaviors through the use of a brief screening questionnaire, as well as to identify potential facilitators and barriers to adherence. Participants were recruited from the University of Houston–Clear Lake and asked to complete the screener embedded within the Psychology Student Research Pool prescreen. Upon indicating that they have received at least one recommendation to modify health-related behaviors from a healthcare provider, participants were invited to complete the second and third phases of the study. Analyses consisted of using hierarchical regressions and a principal component analysis to identify constructs that either facilitate or act as a barrier to adherence. Findings suggest a relationship between adherence, self-efficacy (e.g., general, health), and constructs supported by the Health Belief Model and Theory of Planned Behavior (e.g., perceived behavioral control)
Inventory of STS-41-F Documents
These are documents related to STS-41-F and are arranged chronologically. They include Cargo Systems Manuals and Flight Data Files documents, dated Nov. 1983 to June 1984