Trijurnal E-Journal Universitas Trisakti
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KORELASI KADAR LEUKOSIT DAN KESADARAN DENGAN LAMA PERAWATAN PASIEN CEDERA KEPALA USIA DEWASA MUDA
No full textLATAR BELAKANG
Menurut data riset kesehatan dasar (Riskesdas) provinsi Daerah Khusus Ibukota (DKI) Jakarta tahun 2018 menunjukan bahwa 11,79% kasus cedera adalah kasus cedera kepala. Peningkatan leukosit setelah cedera bisa diasosiasikan dengan masa perawatan yang lebih lama.Variabel yang paling penting dalam memprediksi lama perawatan pasien cedera kepala adalah dengan menggunakan GCS. Penelitian ini dilakukan untuk mengetahui korelasi kadar leukosit dan kesadaran dengan lama perawatan pasien cedera kepala usia dewasa muda.
METODE
Jenis penelitian ini adalah penelitian observasional analitik dengan pendekatan cross-sectional. Untuk mengetahui korelasi antara kadar leukosit dan kesadaran dengan lama perawatan pasien cedera kepala usia dewasa muda dengan cara mengalisis rekam medis pasien cedera kepala di RS Husada yang berusia 18-40 tahun Februari 2018 sampai dengan Februari 2020. Analisis data menggunakan uji korelasi Pearson dengan program SPSS V26.0 for windows dengan tingkat kemaknaan yang digunakan 0,05.
HASIL
Korelasi kesadaran dengan lama perwatan memiliki nilai p-value= 0.339, Korelasi kadar leukosit dengan lama perawatan pasien cedera kepala dewasa memiliki p-value= 0,5
KESIMPULAN
Penelitian ini menunjukkan bahwa tidak terdapat korelasi antara kesadaran dengan lama perawatan pasien cedera kepala usia dewasa muda dan tidak terdapat korelasi antara kadar leukosit dengan lama perawatan pasien cedera kepala usia dewasa muda.
KOMBINASI TERAPI SEMAGLUTIDE INJEKSI DAN DIETHYLPROPION HCL ORAL PADA PASIEN OBESITAS: LAPORAN KASUS
No full textObesitas merupakan penyakit metabolik kronis multifaktorial dengan prevalensi yang meningkat pesat secara global. Terapi farmakologis menjadi alternatif penting bagi pasien yang gagal mencapai target penurunan berat badan melalui modifikasi gaya hidup. Semaglutide, agonis reseptor GLP-1, dan diethylpropion, agen simpatomimetik anorektik, bekerja melalui mekanisme berbeda dan berpotensi memberikan efek sinergis bila dikombinasikan. Deskripsi kasus: Seorang wanita 37 tahun dengan obesitas (IMT 27,48 kg/m²) menjalani terapi semaglutide 0,25 mg/minggu yang ditingkatkan menjadi 0,5 mg/minggu pada minggu ke-6, dikombinasikan dengan diethylpropion oral 1x/hari. Dalam delapan minggu, berat badan pasien menurun dari 73,9 kg menjadi 62,9 kg (−14,9%), IMT menjadi 23,4 kg/m², dan massa lemak tubuh berkurang dari 27,5 kg menjadi 20,6 kg. Tidak ditemukan efek samping bermakna.Diskusi: Penurunan berat badan yang signifikan dalam waktu singkat menunjukkan efek sinergis antara semaglutide dan diethylpropion. Semaglutide meningkatkan rasa kenyang dan memperlambat pengosongan lambung, sedangkan diethylpropion menekan nafsu makan melalui stimulasi norepinefrin di sistem saraf pusat. Kombinasi keduanya memperkuat efek anorektik dan menurunkan massa lemak tubuh tanpa menimbulkan efek kardiovaskular.. Kesimpulan: Kombinasi semaglutide dosis rendah dan diethylpropion oral memberikan hasil efektif dan ditoleransi baik pada pasien obesitas refrakter, dengan potensi menjadi alternatif terapi multimodal yang efisien dan aman., namun memerlukan penelitian lebih lanjut untuk menilai keamanan jangka panjan
Potensi Aktivitas Antikanker Ekstrak Etanol Daun Peperomia pellucida L. Kunth Terhadap Lini Sel HSC-3
Get PDFBackground: One of the most prevalent cancers worldwide is oral cancer, with approximately 90% of cases being squamous cell carcinoma. P. pellucida has potential as a chemopreventive agent due to its secondary metabolites, including flavonoids, which are known to have anticancer activity. Objective: The review aimed to explore potential directions for future research on treatment of oral cancer using of P. pellucida. Method: The references for this review were gathered from Google Scholar, PubMed, official reports, and global health organizations websites, using keywords like “Peperomia pellucida L. Kunth”, “apoptosis”, “oral cancer”, “anticancer”, and “HSC-3 cell line” from 2014 to 2024. This review considered references available in both English and Indonesian. Main finding: P. pellucida has been used in anticancer research due to its content of various phytochemical compounds, such as flavonoids. Previous studies have demonstrated the anticancer properties of P. pellucida against MCF-7, HT-29, and THP-1 cell lines. However, research specifically examining the anticancer potential of P. pellucida against oral cancer has not been reported. Conclusion: Several studies have reported that P. pellucida demonstrates potential as an anticancer agent. Further investigation is required to explore its capability in oral cancer therapy
Pengaruh usia dan jenis kelamin Terhadap periodontitis
Get PDFBackground: Periodontitis is a chronic inflammatory disease that affects the supporting structures of the teeth, characterized by progressive destruction of the periodontal ligament and alveolar bone. The severity of this condition is influenced by various factors, including age and sex. Objectives: To observe the influence of age and sex on periodontitis. Methods: This article reviews several literature regarding the influence of age and sex on progression of periodontitis. Results: As age increases, there is a decline in the regenerative capacity of tissues, along with greater exposure to risk factors such as plaque accumulation, systemic diseases, and a weakened immune response, all of which contribute to the progression of periodontitis. In addition, sex also plays a role, with males and female equally showed influence on the progression of periodontitis
Hambatan Oklusi dan Artikulasi Sebagai Faktor Trauma Oklusi Sekunder pada Pasien Periodontitis: Tinjauan Pustaka
Get PDFOcclusal trauma is a pathological condition that occurs as a result of excessive occlusal forces that exceed the adaptive capacity of the periodontal tissues. Although not the primary cause of periodontitis, occlusal trauma can exacerbate existing periodontal inflammation and accelerate the destruction of supporting tooth structures. Occlusal interferences, such as premature contacts, as well as articulation interferences or blocking during mandibular movements, are factors that can increase the mechanical load on the periodontium. These disturbances may lead to secondary occlusal trauma in teeth with compromised periodontal support. Understanding occlusal and articulation interferences is essential for maintaining periodontal health, as proper occlusal adjustment and functional balance can help prevent further damage to the tooth-supporting tissues. This study aims to review the role of these interferences on secondary occlusal trauma in periodontitis patients
Adaptive Occupational Safety Mechanism for Autonomous Material Handling: A Zone-Based Dynamic Risk Assessment Approach
Get PDFThe integration of Autonomous Guided Vehicles (AGVs) into shared industrial workspaces requires robust safety mechanisms to mitigate collision risks without compromising operational efficiency. Conventional binary safety systems often trigger abrupt emergency stops, leading to mechanical wear and production bottlenecks. This study aims to develop an adaptive decision-making framework for AGV safety based on real-time spatial risk assessment. The proposed approach uses a 3D LiDAR sensor to map unstructured environments and employs the Density-Based Spatial Clustering of Applications with Noise (DBSCAN) algorithm to identify dynamic obstacles. A multi-tiered risk zone logic—comprising Danger, Caution, and Ready zones—is implemented to regulate braking responses compliant with ISO 12100 standards autonomously. Experimental validation was conducted through static, linear, and complex non-linear trajectory scenarios. Results indicate that the system successfully eliminates environmental noise and maintains continuous object tracking during erratic movements, triggering gradual deceleration rather than abrupt halts in non-critical situations. This research contributes a scalable safety protocol that enhances Occupational Health and Safety (OHS) compliance while maintaining smoother intralogistics flow on the production floor
Sustainable Utilization of Industrial Solid Waste in Lightweight Concrete Blocks to Support Environmentally Friendly Cities
Get PDFAim: This study aims to evaluate the influence of gold tailings waste (GTW), nickel slag (NS), and rejected plastic (RP) as partial substitutes for cement and fine aggregates on the mechanical and physical properties of lightweight concrete blocks for sustainable construction applications. Methodology and Results: GTW was substituted at 5% by weight of cement, while NS and RP replaced fine aggregates at variations of 10–20% and 10–15%, respectively. Concrete specimens were cast, cured, and tested in accordance with SNI and ASTM standards. Compressive strength and density were measured at 7, 14, and 28 days, while splitting tensile strength and porosity were evaluated at 28 days. The results show that compressive strength increased with curing age, reaching 1.56–2.37 MPa at 28 days. The optimal mixture (BR 5GTW 20NS 10RP) achieved 1.93 MPa, exceeding the minimum SNI requirement of 1.8 MPa for lightweight concrete blocks. Density values ranged from 683 to 1001 kg/m³, confirming the lightweight classification. Splitting tensile strength ranged between 0.315 and 0.388 MPa, while porosity varied from 4.38% to 8.12%, indicating acceptable physical performance. Conclusion, Significance, and Impact of the Study: The incorporation of GTW, NS, and RP enhances mechanical performance while maintaining appropriate density and porosity. This approach offers a sustainable and cost-effective construction material by valorizing industrial waste, reducing environmental burdens, and supporting environmentally responsible urban infrastructure development
EVALUASI TREN RISET JALAN RAYA DAN TRANSPORTASI CERDAS DI INDONESIA MENGGUNAKAN PENDEKATAN BIBLIOMETRIK
No full textPenelitian ini bertujuan untuk mengevaluasi tren penelitian terkait jalan raya dan transportasi cerdas di Indonesia dengan menggunakan pendekatan bibliometrik. Metode yang digunakan adalah analisis kuantitatif terhadap metadata publikasi ilmiah yang diperoleh dari basis data internasional selama periode tahun 2000 hingga 2024. Data yang diperoleh dianalisis menggunakan perangkat lunak visualisasi bibliometrik untuk mengidentifikasi pola pertumbuhan publikasi, produktivitas penulis dan institusi, jaringan kolaborasi, serta distribusi dan perkembangan tema kata kunci. Hasil penelitian ini menunjukkan adanya peningkatan signifikan dalam jumlah publikasi ilmiah dalam dua dekade terakhir, khususnya dalam bidang sistem transportasi cerdas, keselamatan lalu lintas, keberlanjutan infrastruktur, dan mobilitas perkotaan. Institusi pendidikan tinggi di Indonesia menjadi kontributor utama dalam publikasi, dengan tren peningkatan kolaborasi internasional. Pemetaan kata kunci memperlihatkan pergeseran fokus penelitian dari teknik jalan konvensional menuju penerapan teknologi berbasis digital dan solusi mobilitas pintar. Kesimpulan dari penelitian ini menunjukkan bahwa perkembangan riset transportasi di Indonesia mengarah pada pendekatan yang lebih inovatif dan berkelanjutan, sejalan dengan kebutuhan nasional untuk mewujudkan sistem transportasi yang tangguh, efisien, dan ramah lingkungan. Hasil kajian ini memberikan gambaran menyeluruh mengenai arah perkembangan keilmuan di bidang transportasi di Indonesia serta dapat dijadikan dasar pengambilan keputusan bagi peneliti, pembuat kebijakan, dan pemangku kepentingan dalam merancang strategi riset dan pembangunan transportasi nasional ke depan
Modeling the Effects of Customer Trust and Satisfaction on Behavioral Intention among E-Commerce Users in Makassar
Get PDFThis study examines the impact of customer trust and customer satisfaction on customer behavior intention within the e-commerce sector in Makassar. The Quantitative analysis with 100 respondents and SmartPLS 4.1 for structural equation modeling indicates that customer trust does not exert a substantial direct influence on customer behavior intention, suggesting that trust primarily serves as a foundational expectation rather than a catalyst for purchasing behavior. In fact, customer satisfaction exhibits a robust and large positive influence on customer behavior intentions, illustrating the viral role of service quality, precise product delivery, and the whole shopping experience in influencing consumer behavior. The results indicate that in a developed e-commerce environment, customer happiness is the principal factor influencing behavioral intention, whereas trust functions as a fundamental prerequisite rather than a driving force. The study offers actionable insights for e-commerce managers to focus on techniques that enhance customer satisfaction and suggests directions for future research to include wider variables and diverse regional contexts
PENJATUHAN SANKSI PIDANA TERHADAP ANGGOTA KEPOLISIAN YANG KARENA KEALPAANNYA MENYEBABKAN KORBAN MENINGGAL: The Imposition of Criminal Sanctions on Police Officers Whose Negligence Results in the Death of a Victim
Get PDFEvery citizen, including members of the police force, holds equal status before the law, including when involved in actions that result in criminal liability due to negligence. The issues discussed in this research concern the judge\u27s considerations in imposing criminal sanctions for negligence causing death by a police officer, as well as the application of criminal liability for such negligence in Decision Number 55/Pid.B/2024/PN Plk based on Article 359 of the Indonesian Criminal Code (KUHP). The research method used is normative legal research with a descriptive-analytical approach, utilizing secondary data and drawing conclusions through deductive reasoning. The result concludes that Decision Number 55/Pid.B/2024/PN Plk affirms that police officers can be held criminally liable for negligence resulting in death, as regulated in Article 359 of the KUHP. Although the offender acted in the context of duty, the element of negligence remains the basis for imposing criminal sanctions. This decision reflects the application of the principle of equality before the law and serves as an important precedent in upholding the rule of law and accountability of law enforcement officers