CancerData
Not a member yet
37 research outputs found
Sort by
EuroCAT Umbrella Protocol for NSCLC
No full textFor the EuroCAT project, a research protocol that describes a standardized data collection for non-small cell lung cancer was written and has been approved by the Medical Ethical Board of our hospital. A copy of the protocol and the appendices, including scoring of side effects, quality of life questionnaires and optional biobank procedure can be downloaded below. Patient information and the informed consent sheet are available in four languages (English, Spanish, French and Chinese).
It is allowed to adapt the documents, so that they match the requirements of your hospital and..
Prognostic value of metabolic metrics extracted from baseline positron emission tomography images in non-small cell lung cancer.
No full textBACKGROUND: Maximum, mean and peak SUV of primary tumor at baseline FDG-PET scans, have often been found predictive for overall survival in non-small cell lung cancer (NSCLC) patients. In this study we further investigated the prognostic power of advanced metabolic metrics derived from intensity volume histograms (IVH) extracted from PET imaging.METHODS: A cohort of 220 NSCLC patients (mean age, 66.6 years; 149 men, 71 women), stages I-IIIB, treated with radiotherapy with curative intent were included (NCT00522639). Each patient underwent standardized pre-treatment CT-PET imaging. Primary GTV..
The prognostic value of temporal in vitro and in vivo derived hypoxia gene-expression signatures in breast cancer
No full textStandard Follow Up Program For Head And Neck Cancer Patients
No full text
Definitive Version: 1 january 2012
Authors:
Prof. dr. J.A. Langendijk, Department of Radiation Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Prof.dr. P Lambin. Department of Radiation Oncology (MAASTRO), Maastricht University Medical Center Maastricht (MUCM+), The Netherlands
General objective of the SFP
The primary and general objective of the clinical introduction of the SFP as the current standard of care is to improve the quality of radiotherapy for head and neck cancer patients by reducing radiation-induced..
A semiautomatic CT-based ensemble segmentation of lung tumors: comparison with oncologists' delineations and with the surgical specimen.
No full textPURPOSE: To assess the clinical relevance of a semiautomatic CT-based ensemble segmentation method, by comparing it to pathology and to CT/PET manual delineations by five independent radiation oncologists in non-small cell lung cancer (NSCLC).MATERIALS AND METHODS: For 20 NSCLC patients (stages Ib-IIIb) the primary tumor was delineated manually on CT/PET scans by five independent radiation oncologists and segmented using a CT based semi-automatic tool. Tumor volume and overlap fractions between manual and semiautomatic-segmented volumes were compared. All measurements were correlated with the..
Preclinical evaluation and validation of [18F]HX4, a promising hypoxia marker for PET imaging
No full textPET imaging of hypoxia using [18F]HX4: a phase I trial
No full text Download the images using these instructions and this DOI : 10.1007/s00259-010-1437-x Background and purposeNon-invasive PET imaging of tumour hypoxia could help in the selection of those patients who could benefit from chemotherapy or radiation with specific antihypoxic treatments such as bioreductive drugs or hypoxic radiosensitizers. In this phase I trial, we aimed to determine the toxicity of [18F]HX4, a member of the 2-nitroimidazole family, at different dose levels. The secondary aim was to analyse image quality related to the HX4 dose and the timing of imaging.MethodsPatients with a..