5257 research outputs found
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014-Thin Film Deposition for Scintillator Detectors
Get PDFA plastic scintillator detector was developed for an experiment carried out at the Laboratory for Laser Energetics (LLE) at the University of Rochester. Scintillators can be used as detectors of energetic charged ions; for this experiment at LLE, scintillators were used to detect protons and deuterons accelerated by laser light during the experiment. However, uncoated scintillators are sensitive to visible light as well as charged particles, and the residual laser light interferes with the measurement of the ions. The Thin Film Evaporator at SUNY Geneseo was used to coat the scintillators with a metal film thick enough to absorb the visible light and thin enough so that the energy loss of the ions was minimized. The optimal film thickness was found to be 200 nm of Aluminum; this thickness was found to block out external visible light without significantly degrading the energy of the charged ions. Samples were mounted above an aluminum source in the bell jar and a base pressure of 10-6Torr was achieved. By passing a high current through the source holder, a thin film of aluminum was deposited while the thickness of the deposition was monitored using a rate deposition monitor. For some scintillator samples, multiple depositions were required to coat all sides of the scintillator. The coated scintillation detectors performed as expected for the LLE experiments
256-Assessing the Use of Next Generation MinION Nanopore DNA Sequencing in Obtaining High Quality Data from Zebra Fish to Inform Round Scad Fish Epigenetics under Global Climate Stress
Get PDFThe issue of climate change has been gaining increased awareness and attention globally in recent years. It is having various impacts to ecosystems all over the world, causing many species to become environmentally stressed. Epigenetics is a concept that is being studied more prevalently regarding climate changes. Due to the changing environment, stress-induced heritable traits may appear without changes to the genomic code, known as epigenetic alterations. One such epigenetic alteration is DNA methylation, which occurs in cellular responses to environmental stress. One major source of affordable protein in the Philippines comes from the wild Round Scad fish, which has recently been facing rapid decline in both its population and body size. The purpose of our study is to explore the patterns of DNA methylation in wild Round Scad to determine whether these changes are associated with an epigenetic response to global climate stress. Samples of Round Scad DNA were collected and isolated from the Philippines. Using nanopore MinION, a portable third generation DNA sequencing technology, we are able to obtain high quality DNA sequences required for detection of methylation sites. However the DNA sequences are short, needing improvement. To facilitate our analysis we are sequencing the genome of the Zebrafish for comparison. Here, we shall report on the initial data collected. We anticipate that long term findings from this project will provide critical information to manage wild Round Scad and other marine fish facing similar environmental stressors
132-How Does a Genetic Risk for Alzheimer’s Disease and Alcohol Use Affect Memory in a Mouse Model?
Get PDFAlzheimer’s disease (AD) is the most common type of dementia, characterized by progressive memory loss and cognitive decline. The prevalence of this disorder is expected to be on the rise, and affects a great number of people. APOE4 is a variant allele found to increase the risk of AD. In addition, the consumption of alcohol exacerbates the onset and magnitude of AD, while also having its negative effects on cognition, potentially by increasing neuroinflammation. We have a knock-in mouse model with the human APOE4 gene that will be used to test the effects of this gene (APOE4) by environment (alcohol) interaction on memory. We expect to observe cognitive impairments that emerge over time due to the increased APOE4 gene expression. We also hypothesize that alcohol will exacerbate the risk of early cognitive impairments in the APOE4 mice compared to the control mice. Understanding how everyday choices such as alcohol use can interact with our genetic predisposition to AD has significant potential to improve individual outcomes
080-Investigating Reduction of the Ostrich Forelimb: Palaeognathae (Aves)
Get PDFPalaeognathae is a group of flightless birds classified by the absence of the keeled sternum (breastbone) present in flighted birds. As they diverged from their flighted ancestors, palaeognaths developed cursorial traits such as greater body mass and elongated hindlimbs, and concomitant with this was the reduction of the forelimbs, which were no longer needed for flight. Among living paleognaths, most species exhibit extreme forelimb reduction, such as that seen in the ostrich (Struthio camelus). This study investigates the variation betweenS. camelusindividuals to provide clues as to which behaviors and environmental pressures may have contributed most to forelimb morphology. Differences in the forelimb elements of males and females, indicating sexual dimorphism in the wing, would suggest variation results from sex-specific functions such as mating displays. Comparison between captive and wild populations could show variation resulting from presence of competition, predation, and other environmental factors. Using geometric morphometric software principal component (PC) data was analyzed to investigate variation between forelimb elements and test adherence to the hypothesized pattern of limb reduction in which reduction occurs distal to proximal. The aim of this project is to investigate the current variation in morphology of the palaeognath taxa using geometric morphometrics, which quantifies the shape of the bones. These methods will allow us to contrast interspecies and intraspecies variation to quantify how functional demands on the wing affect morphological variation of the bones, and thus better understand the evolutionary relationship between form and function in cases of limb reduction
252-Long-Term Trends in Dominance of Mustard Hill Coral in San Salvador Reefs
Get PDFCorals throughout the Caribbean have been declining in abundance for the past three decades, yet one stony coral species commonly known as Mustard Hill (Porites astreoides) has become more dominant. However, a recent study conducted in the Virgin Islands showed that Mustard Hill coral populations have declined. Our research team studied corals in previously surveyed reefs around San Salvador Island, The Bahamas, to determine the trajectory of Mustard Hill populations. Specifically, we wanted to know if the populations had changed since they were last studied in 2019. Data on coral species abundance and percent cover were collected at both Rocky Point and Telephone Poles patch reefs by photographing sections of 10 meter transect lines. Image analysis of percent cover using ImageJ software is underway. Our initial observations point toward a decline in Mustard Hill abundance, possibly due to the effect of widespread disease in these populations. However, other coral species may be experiencing similar losses. Once the results of our surveys are processed and analyzed, we will be able to compare our numbers to those in previous studies conducted to see how Mustard Hill populations are changing
344-Miming Makes it Memorable? Investigating the Role of Iconic Signs in Memory
Get PDFOne useful mnemonic technique that can improve memory retention is the production effect: the finding that information is better remembered when it is actively produced (i.e., spoken aloud or signed) than when it is passively received (i.e., read silently). Regarding how signing can help memory, we developed a study to investigate how the “iconicity” of signs could help memory. Iconicity is the extent to which the form of a sign resembles its meaning. For example, in ASL, the sign for book involves holding a closed, imaginary book with both hands, and then opening it with a quick flick of the wrists. The sign for “book” is much more iconic than the sign for other words, such as “justice” or “parent”, because the forms of these signs do not resemble its meaning. We hypothesize that one of the reasons signing may be a highly effective mnemonic is that many signs are iconic of their referent words, meaning that signing can be thought of as “acting out” a word or action. In our study, subjects were shown a list of words that varied in ratings of iconicity (high or low), signed some of the words. Later, their memory for these words were tested. Our results suggest that iconic signs were indeed easier to remember than non-iconic words however, this effect held true for both signed and non-signed items. Overall, iconicity may thus enhance memory, but also may not depend on signing, a concept we are exploring with further research in the lab
251-Bone Fracture Repair: Analysis of Mechanical Strength and Porosity Properties of Biocompatible Collagen Cements
Get PDFCalcium phosphate-based cements (CPCs) have been under investigation for use in setting and repairing bone fractures as a method to replace auto-grafting. Hydroxyapatite (HA) is a calcium phosphate mineral and the main mineral component of bone, making it a suitable basis for biocompatible cements. HA cements alone however lack mechanical strength and the porosity required for osteocyte ingrowth and proliferation. In this study, we examine the addition of a protein polymer collagen on the mechanical strength and pore structure of a HA-based CPC via measurements of shear strength and compressive strength, as well as scanning electron microscopy. The study is an ongoing investigation, and the data obtain thus far is presented and discussed
133-Paleomagnetism of a Dike in Kelso, CA
Get PDFAn igneous intrusion was discovered while completing a geologic mapping project on the Kelso 7.5-minute quadrangle in San Bernardino California. This dike is located at 35 degrees 3’47” N and 115 degrees 40’47” and has an unknown age. The objective of our research entails examining samples extracted from the dike, using a paleomagnetic demagnetization experiment to determine the age of when the dike was emplaced. Samples were collected during a research expedition to Southern California. On site they were orientated and collected. They were then brought back to the lab where they had cores drilled on them. Of the cores drilled five were usable. They were then spun on the spinner and subjected to incremental heating until the temperature of 700 degrees Celsius was met. Results wield an average declination of 162.6 and an average inclination of 22.4. These results are promising but the potential rotation of the sample suggests more samples are needed to conclusively determine the age of this dike
Bailey Hall in Winter, SUNY Geneseo
No full textPhotograph of the Guy A. Bailey Science Building south-east face, Geneseo, N.Y. Snow is on the ground, and pictured is a car parked beneath the Bank St. and Wadsworth St. signs. During 1950-1951 the four residence halls (Bailey, Fraser, Blake, and Sturges) accommodated 204 women students and the College Center, with dining room, snack bar, lounge, post office and browsing and game rooms were occupied. Mr. Bailey graduated from the Cortland Normal in the classical course in the year 1898.https://knightscholar.geneseo.edu/cap-bailey/1003/thumbnail.jp
A. H. Southard, Canaseraga, New York
No full textClass of 1894https://knightscholar.geneseo.edu/cap-as-identified/1006/thumbnail.jp