Varna Medical University Press: Journals
Not a member yet
8984 research outputs found
Sort by
Assisted reproduction and increased risk for mother and child
Full text linkAssisted reproduction (AR) is becoming more widespread, with frequency increasing since the introduction of the methodology in the early 1980s, varying between 2% and 8% of births depending on the country. According to a comprehensive study by the International Monitoring Committee on Assisted Reproductive Technologies, between 9.8 and 13 million babies worldwide were born via AR between 1978 and 2018, and over 150 million children, or 1.4% of the world's population, will be "assisted" conceived by the end of the century. Observations based on the growing number of women who resorted (with or without success) to this method, on the one hand, and, on the other, on the increasing number of births through AR, allow us to draw sufficiently eloquent conclusions about its safety. Data show that AR is associated with an increased incidence of cardiovascular events in mothers and newborns, which places this group of patients in a category with increased risk of long-term incidents and peripartum complications.The presented review provides a relatively in-depth summary of many of the currently conducted follow-up studies of women undergoing AR methods and children born after successful conception. The most common problems are indicated, as well as the possible pathogenetic mechanisms for them.Infertility incidence is increasing due to socio-economic and environmental factors in modern society. AR may be the only option for many couples to fulfill their dream of having a child. It is important in these circumstances to be clear about the positive aspects and the risks, so that as a result of advances in medicine, the latter can be minimized
New antibiotics approved by EMA and FDA (2020–2024): Trends, access in Bulgaria, and implications for antimicrobial resistance control
Full text link The aim of the study is to identify trends by analyzing the new antibacterial drugs approved by the EMA and FDA during the period 2020-2024, which can be used for planning antibiotic policies in healthcare institutions providing hospital care. The methodology of the study includes the collection and analysis of data from regulatory agencies and scientific sources on the antibiotics approved for use in the European Union and the USA during the study period
Cosmetic products and kidney diseases: A medical analysis
Full text linkCosmetic products contain a wide array of chemical compounds, some of which may exert significant nephrotoxic effects. This study aims to systematically examine the association between the use of specific cosmetic products and the risk of kidney diseases by investigating the mechanisms through which these chemicals affect renal function. The analysis encompasses compounds such as glyoxylic acid, inorganic mercury, dibutylphthalate, triclosan, formaldehyde-releasing agents, and per- and polyfluoroalkyl substances (PFAS). The findings underscore the need for heightened awareness and the development of stricter regulatory measures to mitigate the potential nephrotoxicity of cosmetic products
Treatment of multiple gingival recessions in the aesthetic zone of the maxilla with coronally advanced flap with a lateral approach and a tunnel technique. A case report
Full text link Introduction: The presence of multiple recessions in the aesthetic zone of the upper jaw are associated with aesthetic dissatisfaction of the patient and hypersensitivity of the exposed root surfaces. Different surgical methods are indicated for the treatment of such clinical cases, allowing simultaneously complete root coverage of the exposed surfaces and maximum aesthetic result – matching the colour and equal borders of the mucogingival line. The triangular coronally advanced flap (CAF) demonstrates good aesthetic results and a high percentage of root coverage. Aim: The purpose of the presented clinical case is to demonstrate the efficacy of the triangular CAF with lateral approach in the therapy of multiple recessions in a patient with high aesthetic requirements. Case Presentation: A 35-year-old man with multiple Miller class 1 recessions in the aesthetic zone of maxilla was treated with a triangular CAF procedure with a lateral approach and, additionally, a tunnel technique between the central incisors was applied. Results: A harmonious gingival margin, complete root coverage, satisfactory aesthetics, and also elimination of hypersensitivity in the cervical area of the treated teeth are shown as a result of this surgical method for therapy of multiple gingival recessions. Conclusion: The presented case demonstrates good aesthetic results and 100% success using the triangular CAF technique in the treatment of multiple gingival recessions and confirms the good prognosis with this technique
Herapathite—history and utilization
Full text linkINTRODUCTION: The remarkable history of the herapathite crystal is an example of how a simple chemical reaction from the 19th century leads to successful achievements in various fields of science and business. In the field of pharmaceutical analysis, the herapathite reaction is used as a method for selectively registering the presence of the alkaloid quinine. Moreover, the product, herapathite crystals, has the ability to polarize light, which made it useful in the optical technologies. MATERIALS AND METHODS: The research was conducted in various databases (PubMed, ScienceDirect, ResearchGate, Google Scholar, and others).AIM: This article reveals the history and the utilization of herapathite crystals.CONCLUSION: Over the years, herapathite crystals have challenged the scientific chemistry community. Besides being an analytical sign for determining the presence of alkaloid quinine, herapathite has a great effect on the scientific understanding and utilization of polarized light and the development of modern optical technologies
Technological evolution and its impact on health management
Full text linkHospital managers in the 21st century are faced with the difficult task of, on the one hand, effectively using new technologies to improve medical care, and on the other hand, dealing with the challenges associated with their application, such as ensuring secure access to data and complying with changing regulations and legal provisions. As a result of globalization and the dynamics of the environment, innovations are becoming increasingly important to the life of every institution. Through them, organizations have the opportunity to build unique competitive advantages, enabling them to maintain and develop their market positions. Their implementation depends on the innovation culture of the organization’s management in order to achieve higher efficiency
Structured classification and database integration of medical simulators for educational efficiency
Full text linkIntroduction: Simulation-based education is an essential component of healthcare training, providing a safe environment for acquiring clinical skills. Despite the widespread use of simulators, there is a lack of consistency in terminology and classification, which hampers their effective integration into curricula.Aim: This study aims to analyze the existing classification of medical simulators and propose an improved structure based on their typology and functionality.Materials and Methods: A literature review was conducted to examine the various classifications of medical simulators. The analysis was supported by QDA Miner Lite software for text analysis, which facilitated the identification and categorization of terms and concepts related to the simulators.Results: Twenty-two publications were analyzed, revealing a wide variety of terms used for simulators. Two terms stood out for their frequent use: high-fidelity simulators (66.7%) and simulated or standardized patients (100%). Five main categories of simulators were proposed: high-fidelity simulators, complex task trainers, basic task trainers, software-based simulators, and standardized patients. Definitions were developed for each category to standardize their use and ensure clarity in educational settings.Conclusion: The findings emphasize the need for standardizing the terminology and classification of medical simulators. The proposed classification system offers clear definitions and can be used to more effectively integrate simulators into healthcare educational programs
The role of automation in terminals and innovative management for effective management in the maritime sector
No full textThe integration of information data flow in maritime sector results from continued interest to the new era of technologies in which the high level of safety standards bearing in mind the increasing of potential threats and possibility for cyber-attacks in vulnerable areas of critical maritime infrastructure. The implementation of artificial intelligence increases the technical potential for good cooperation between companies in the maritime business. This paper discuss the problems with digitalization and complex automation of process in transport terminals and the role of innovation management in the implementation of effective management processes
The role of discipline in building resilience. A mediatory model for the influence of the strictness of order on the level of resilience in students at the Nikola Vaptsarov Naval University
No full textThe Naval Academy prepares future maritime professionals for the military and civilian fleets. It is important for future naval specialists to have good mental resilience, ensuring their ability to cope with the increased demands of the environment. The aim of the study is to track the impact of the environment – educational and military-educational – on the level of resilience, taking into account the impact of two main factors: strictness of order and positive relationships. It is considered that the level of resilience develops in the learning process under the influence of the environment and its requirements. The derived mediator model shows the influence of discipline (strictness of order) on the level of resilience in students, refracting through the mediator positive relationships. The results obtained show that students in a military profile have a higher level of resilience. This can be explained by the increased demands of the environment in terms of discipline and subordination, which are successfully perceived by the cadets thanks to the established team functioning
Some specifics of control in conditions of nonlinearity of a dynamic external environment
No full textThe situational awareness directly corresponds to the ability to consider what is happening in the surrounding security environment, and to control processes, effects, and environment. The adequacy of control needs a designated high level of connectivity. So, when the system is open beyond given limits, the control and situational awareness become problematic. The reality requires a constant upgrade and transformation of the understanding of the "external" multidimensional environment which changes extremely in a dynamic and non-linear way. These factors make any given complex system unstable and difficult to predict and control. Then, the response of decision-makers can be based on the control by use of adaptive nonlinear dynamic systems