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Mechanism of smoothened localization to the primary cilium in hedgehog signal transduction
No full texthonors thesisCollege of Social & Behavioral ScienceBiologyBenjamin MyersThe Hedgehog (Hh) pathway is a vital cellular signaling pathway involved in embryonic development and general tissue homeostasis in vertebrates. Aberrant activation of hedgehog signaling has implications in developmental disorders and multiple forms of cancer [1,28,41]. The pathway is activated when Hh proteins bind to their receptor Patched (PTCH1) which relieves inhibition on G-protein coupled receptor (GPCR) like protein, Smoothened (SMO). SMO can then bind cholesterol, activating the protein and triggering GRK mediated phosphorylation and PKA binding, preventing phosphorylation of gliomaassociated (GLI) transcription factors and allowing for Hh target genes to be transcribed [3,13,15,35]. Hedgehog singling takes place in the primary cilium, an antennalike, membrane bound signaling hub found along the periphery of most cells in vertebrates. [6,11,30,34]. Importantly, protein synthesis does not occur in the primary cilium. Therefore, ciliary signaling function requires proteins to be targeted to the ciliary membrane [30]. Targeting and entry of signaling proteins to the primary cilium is a tightly regulated process, mediated by a variety of mechanisms, most of which are not conserved across different ciliary signaling pathways. Even though SMO is known to signal via the primary cilium, the mechanism by which it localizes to the organelle is not entirely clear. To address this question, we developed cell lines containing specific SMO C-tail truncations and completed a variety of drug-based assays followed by antibody staining and confocal microscopy to visualize SMO localization in vitro. While the current understanding of SMO ciliary localization is based on ubiquitination of the third intracellular loop (ICL3) of inactive SMO and shuttling from the cilium, previous work indicates that the C-tail of SMO is necessary for ciliary localization and contains two, partially redundant, ciliary localization sequences (CLS1 and CLS2) [7,19,22,25]. Our preliminary work illustrates a preliminary mechanism by which localization via the membrane-proximal CLS1 is independently mediated through activity-dependent PKA/GRK2/3 interactions with SMO, while the more membrane-distal CLS2 is mediated by ubiquitination of inactive SMO. Understanding the intricate mechanism by which SMO localizes to the primary cilia is crucial in developing treatments to Hedgehog-related pathologies
Role of the oncogene E26 tranformation-specific sequence-i in arteriovenous fistula maturation failure
No full texthonors thesisCollege of EngineeringBiomedical EngineeringYang-Ting ShiuAbout 15% of the adult United States (U.S.) population is affected by chronic kidney disease (CKD) [1]. Almost 70% of end-stage kidney disease patients in the U.S. need hemodialysis to survive [2]. A vascular access point must be created for hemodialysis to occur. The current gold standard for vascular access points is the arteriovenous fistula (AVF) as it lasts the longest [3]. After its creation, an AVF must successfully mature to be useful. AVF maturation failure often occurs due to excess cell proliferation into the AVF\u27s lumen, called neointimal hyperplasia. When AVF maturation failure occurs, hemodialysis can no longer occur because blood cannot flow through the vascular access point at the needed rate. The aim of this project is to investigate whether E26 transformation-specific sequence-1 (ETS-1) causes neointima hyperplasia after arteriovenous fistula creation surgery in a rat model with chronic kidney disease. The leading hypothesis is that ETS-1 inhibition decreases neointima hyperplasia in the AVF following vascular injury. Histological analysis of ETS-1 gene knockout (KO) and wild-type (WT) rats with AVFs in healthy and induced CKD models was performed, and morphometric analysis was used to quantify the open lumen percentage of AVFs in all four groups. No statistically significant difference in open lumen percentage was found at both Week 1 (on average, WT with CKD: 86.3% at n=4; KO with CKD: 78.9% at n=2) and Week 4 (on average, WT with CKD: 31.9% at n=4; KO with CKD: 63.6% at n=2) between the four experimental groups. Further analysis of rats at both Week 1 and Week 4 is needed to draw conclusions regarding the relationship between ETS-1 inhibition and neointimal hyperplasia formation. Further translational research into inhibition of the ETS-1 pathway may be worthwhile and lead to the development of therapies for prevention of neointimal hyperplasia, improved AVF maturation rates, and reduced need for revisit surgeries, enhancing the quality of life for patients with CKD
Nov. 28, 2025; #12 University of Utah vs. University of Kansas
No full textFootball game statistics; game bookAttendance: 32,811; Head Coach Kyle WhittinghamFootballUtah 31; Kansas 21Scoring Summary report Utah vs Kansas (Nov 28, 2025) Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 Utah (10-2, 7-2) vs Kansas (5-7, 3-6) SCORE BY QUARTERS Team 1st 2nd 3rd 4th Total Utah 3 7 0 21 31 Kansas 0 7 7 7 21 SCORING SUMMARY Qtr Time Scoring Play V-H 1st 08:39 UTAH - #17 D.Curtis 34 yd FG, 6-49, 02:41 3-0 2nd 12:03 KU - #9 D.Hishaw Jr. 7 yd rush (#99 L.Marjan kick), 8-73, 03:57 3-7 2nd 09:24 UTAH - #81 J.Buchanan 58 yd pass from #4 D.Dampier (#17 D.Curtis kick), 6-75, 02:39 10-7 3rd 08:15 KU - #6 J.Daniels 1 yd rush (#99 L.Marjan kick), 8-67, 03:54 10-14 4th 12:26 UTAH - #12 L.Simmons 28 yd pass from #4 D.Dampier (#17 D.Curtis kick), 4-80, 01:13 17-14 4th 07:52 UTAH - #9 E.Davis 97 yd interception return (#17 D.Curtis kick), 04:27 24-14 4th 05:32 KU - #87 L.Cure 21 yd pass from #6 J.Daniels (#99 L.Marjan kick), 8-93, 02:14 24-21 4th 02:14 UTAH - #12 L.Simmons 48 yd pass from #4 D.Dampier (#17 D.Curtis kick), 8-85, 03:14 31-21 TIME DETAILS Kickoff time: 11:02 AM End of Game: 02:24 PM Total elapsed: 03:22 OFFICIALS Referee: Mike McCabe Umpire: Brandon Wood Linesman: Matt Burks Line judge: Scott Reilly Back judge: Daniel Young Field judge: Dion Spenard Side judge: Rick Ockey Center judge: Chris Tallent Replay Official: Richard Brown WEATHER Weather: Sunny 33 F Wind: South East 10 mph Individual Statistics report Utah vs Kansas (Nov 28, 2025) Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 FULL GAME UTAH KANSAS No. Gain Loss Net TD Lg Avg No. Gain Loss Net TD Lg Avg Wayshawn Parker RUSHING 12 97 2 95 0 34 7.9 Daniel Hishaw Jr. 22 111 4 107 1 14 4.9 Devon Dampier 11 50 0 50 0 16 4.5 Leshon Williams 15 104 0 104 0 33 6.9 Nate Johnson 1 15 0 15 0 15 15.0 Isaiah Marshall 5 36 0 36 0 13 7.2 Byrd Ficklin 2 7 0 7 0 5 3.5 Jalon Daniels 8 45 11 34 1 16 4.2 Daniel Bray 1 4 0 4 0 4 4.0 Emmanuel Henderson Jr. 1 9 0 9 0 9 9.0 TEAM 4 0 10 -10 0 0 -2.5 51 305 15 290 2 33 5.7 31 173 12 161 0 34 5.2 C-A-I Yds TD Long Sack C-A-I Yds TD Long Sack 15-25-0 253 3 58 0 10-27-3 187 1 54 1 15-25-0 253 3 58 0 10-27-3 187 1 54 Totals: PASSING Devon Dampier Totals: RECEIVING TAR No. Yards YAC TD RUSHING Totals: PASSING Jalon Daniels Totals: Long RECEIVING 1 TAR No. Yards YAC TD Long Dallen Bentley 7 4 29 15 0 11 Cam Pickett 11 5 31 29 0 25 Larry Simmons 6 3 97 23 2 48 Emmanuel Henderson Jr. 6 3 113 26 0 54 Creed Whittemore 4 3 20 7 0 9 Levi Wentz 1 1 22 19 0 22 JJ Buchanan 4 2 65 48 1 58 Leyton Cure 1 1 21 1 1 21 Wayshawn Parker 2 1 32 33 0 32 Keaton Kubecka 1 0 0 0 0 0 Daniel Bray 1 1 5 6 0 5 Boden Groen 3 0 0 0 0 0 Lander Barton 1 1 5 2 0 5 Bryson Canty 2 0 0 0 0 0 25 15 253 134 3 58 Leshon Williams 1 0 0 0 0 0 26 10 187 75 1 54 No. Yds Avg Long In20 TB 2 90 45.0 45 1 0 2 90 45.0 45 1 0 Totals: Totals: PUNTING Orion Phillips Totals: RETURNS No. Yds Avg Long In20 TB 2 85 42.5 48 1 0 2 85 42.5 48 1 0 Punt Kickoff Intercept PUNTING Finn Lappin Totals: RETURNS Punt No Yds Lg No Yds Lg No Yds Lg Levani Damuni 0 0 0 1 9 9 0 0 0 Daniel Bray 0 0 0 1 15 15 0 0 0 Tate Nagy Smith Snowden 0 0 0 0 0 0 1 17 17 Totals: Jackson Bennee 0 0 0 0 0 0 1 0 0 Elijah Davis 0 0 0 0 0 0 1 97 97 0 0 0 2 24 15 3 114 97 Totals: FIELD GOALS Kickoff No Yds Lg No Yds Lg No Yds Lg 0 0 2 43 25 0 0 0 0 0 0 2 23 16 0 0 0 0 0 0 4 66 25 0 0 0 Qtr Time Dist Result 1st 02:16 36 MISSED No. Yards Avg TB 4 231 57.8 1 1 Rush Rcv KR PR IR Total Emmanuel Henderson J… 0 Qtr Time Dist Result 1st 08:39 34 GOOD No. Yards Avg TB OB 6 366 61.0 1 0 Rush Rcv KR PR IR Total ALL-PURPOSE Wayshawn Parker 95 32 0 0 0 127 Emmanuel Henderson Jr. 9 113 43 0 0 165 Larry Simmons 0 97 0 0 0 97 Daniel Hishaw Jr. 107 0 0 0 0 107 Elijah Davis 0 0 0 0 97 97 Leshon Williams 104 0 0 0 0 104 JJ Buchanan FUMBLES Utah - Byrd Ficklin 1-1 Kansas - None 0 65 0 0 0 65 Isaiah Marshall 36 0 0 0 0 36 Dillon Curtis KICKOFFS Dillon Curtis ALL-PURPOSE FIELD GOALS Intercept Laith Marjan KICKOFFS Laith Marjan OB Team Statistics report Utah vs Kansas (Nov 28, 2025) Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 FULL GAME UTAH KU FIRST DOWNS 18 26 Rushing 9 17 Passing 8 7 Penalty 1 2 NET YARDS RUSHING 161 290 Rushing Attempts 31 51 Average Per Rush 5.2 5.7 Rushing Touchdowns 0 2 Yards Gained Rushing 173 305 Yards Lost Rushing 12 15 NET YARDS PASSING 253 187 Completions-Attempts-Int 15-25-0 10-27-3 Average Per Attempt 10.1 6.9 Average Per Completion 16.9 18.7 Passing Touchdowns 3 1 TOTAL OFFENSE YARDS 414 477 Total offense plays 56 78 Average Gain Per Play 7.4 6.1 Fumbles: Number-Lost 2-1 0-0 Penalties: Number-Yards 9-65 4-32 PUNTS-YARDS 2-85 2-90 Average Yards Per Punt 42.5 45.0 Net Yards Per Punt 42.5 45 Inside 20 1 1 50+ Yards 0 0 Touchbacks 0 0 Fair catch 1 2 KICKOFF-YARDS 6-366 4-231 Average Yards Per Kickoff 61.0 57.8 Net Yards Per Kickoff 41.8 37 Touchbacks 1 1 Fair Catch Yards 24 0 Punt returns: Number-Yards-TD 0-0-0 0-0-0 Average Per Return 0.0 0.0 Kickoff returns: Number-Yds-TD 2-24-0 4-66-0 Average Per Return 12.0 16.5 Interceptions: Number-Yds-TD 3-114-1 0-0-0 Fumble Returns: Number-Yds-TD 0-0-0 1--1-0 Miscellaneous Yards 0 0 Possession Time 23:03 36:57 1st Quarter 03:57 11:03 2nd Quarter 08:13 06:47 3rd Quarter 04:30 10:30 4th Quarter 06:23 08:37 Third-Down Conversions 7-13 8-15 Fourth-Down Conversions 0-2 0-2 Red-Zone Scores-Chances 1-2 2-5 Touchdowns 0 3 Field goals 1 0 Sacks By: Number-Yards 1-9 0-0 PAT Kicks 4-4 3-3 2Pts Conversions 0-0 0-0 Field Goals 1-1 0-1 Points off Turnover 17 0 Defensive Statistics report Utah vs Kansas (Nov 28, 2025) Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 FULL GAME UTAH Solo Ast Total Sacks-Yds TFL-Yds FF FR-Yds Int-Yds BrUp Blks QBH 23 Jackson Bennee # Name 7 3 10 0.0-0 1.5-2 0 0-0 1-0 0 0 0 0 Logan Fano 7 3 10 0.5-4 1.5-6 0 0-0 0-0 0 0 3 5 Tao Johnson 3 6 9 0.0-0 0.5-1 0 0-0 0-0 1 0 0 7 Johnathan Hall 3 4 7 0.5-5 1.5-7 0 0-0 0-0 0 0 0 93 Kash Dillon 5 0 5 0.0-0 1.0-2 0 0-0 0-0 0 0 0 15 Lance Holtzclaw 5 0 5 0.0-0 0.0-0 0 0-0 0-0 1 0 0 37 Trey Reynolds 3 1 4 0.0-0 0.0-0 0 0-0 0-0 0 0 0 2 Smith Snowden 2 2 4 0.0-0 0.0-0 0 0-0 1-17 0 0 0 8 Lander Barton 2 2 4 0.0-0 0.0-0 0 0-0 0-0 0 0 1 3 Levani Damuni 2 1 3 0.0-0 0.0-0 0 0-0 0-0 0 0 0 91 Jonah Lea\u27ea 2 1 3 0.0-0 0.0-0 0 0-0 0-0 0 0 0 95 Aliki Vimahi 2 0 2 0.0-0 0.0-0 0 0-0 0-0 0 0 0 98 Dallas Vakalahi 1 1 2 0.0-0 0.0-0 0 0-0 0-0 0 0 0 36 Brock Fonoimoana 1 0 1 0.0-0 0.0-0 0 0-0 0-0 0 0 0 9 Elijah Davis 1 0 1 0.0-0 0.0-0 0 0-0 1-97 0 0 0 71 Caleb Lomu 1 0 1 0.0-0 0.0-0 0 0-0 0-0 0 0 0 35 Cyrus Polu 1 0 1 0.0-0 0.0-0 0 0-0 0-0 0 0 0 16 Blake Cotton 1 0 1 0.0-0 0.0-0 0 0-0 0-0 1 0 0 49 24 73 1.0-9 6.0-18 0 0-0 3-114 3 0 4 Totals KANSAS # Name Solo Ast Total Sacks-Yds TFL-Yds FF FR-Yds Int-Yds BrUp Blks QBH 2 Lyrik Rawls 7 1 8 0.0-0 0.0-0 0 0-0 0-0 0 0 0 4 Trey Lathan 4 0 4 0.0-0 0.0-0 1 1--1 0-0 0 0 0 33 Leroy Harris III 4 0 4 0.0-0 1.0-2 0 0-0 0-0 3 0 0 22 Syeed Gibbs 4 0 4 0.0-0 0.0-0 0 0-0 0-0 0 0 0 11 Devin Dye 3 1 4 0.0-0 0.0-0 0 0-0 0-0 0 0 0 1 3 1 4 0.0-0 0.0-0 0 0-0 0-0 1 0 0 23 Mason Ellis 3 0 3 0.0-0 0.0-0 0 0-0 0-0 0 0 0 27 Taylor Davis 2 0 2 0.0-0 0.0-0 0 0-0 0-0 0 0 0 91 Alex Bray 2 0 2 0.0-0 0.0-0 0 0-0 0-0 0 0 0 0 Austin Alexander 1 1 2 0.0-0 0.0-0 0 0-0 0-0 0 0 0 92 Tommy Dunn Jr. 1 1 2 0.0-0 0.0-0 0 0-0 0-0 0 0 0 94 Blake Herold 1 0 1 0.0-0 0.0-0 0 0-0 0-0 0 0 0 20 Malachi Curvey 1 0 1 0.0-0 0.0-0 0 0-0 0-0 0 0 0 15 Justice Finkley 1 0 1 0.0-0 0.0-0 0 0-0 0-0 0 0 0 5 0 1 1 0.0-0 0.0-0 0 0-0 0-0 0 0 0 37 6 43 0.0-0 1.0-2 1 1--1 0-0 4 0 0 Bangally Kamara Dean Miller Totals Participation report Utah vs Kansas (Nov 28, 2025) UTAH Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 KANSAS Pos ## OFFENSE Pos ## OFFENSE RB 1 Parker, Wayshawn WR 10 Wentz, Levi QB 4 Dampier, Devon WR 11 Canty, Bryson OL 48 Olson, Keith OL 56 Herring, Amir OL 52 Mokofisi, Michael OL 59 Gorczyca, Nolan OL 55 Fano, Spencer QB 6 Daniels, Jalon OL 68 Kump, Jaren OL 61 Foster, Bryce OL 71 Lomu, Caleb OL 70 Baynes, Kobe OL 73 Togiai, Tanoa OL 75 Clements, Calvin WR 80 Whittemore, Creed OL 77 Cruz Jr., Enrique TE 81 Buchanan, JJ TE 88 Groen, Boden TE 88 Bentley, Dallen RB 9 Hishaw Jr., Daniel Pos ## DEFENSE Pos ## DEFENSE DE 0 Fano, Logan CB 0 Alexander, Austin CB 16 Cotton, Blake LB 1 Kamara, Bangally CB 2 Snowden, Smith S 11 Dye, Devin S 23 Bennee, Jackson DE 15 Finkley, Justice LB 37 Reynolds, Trey S 2 Rawls, Lyrik S 5 Johnson, Tao S 27 Davis, Taylor LB 7 Hall, Johnathan LB 4 Lathan, Trey LB 8 Barton, Lander DE 5 Miller, Dean DT 91 Lea\u27ea, Jonah DT 52 Withers, DJ DE 93 Dillon, Kash CB 7 Graham II, DJ DT 95 Vimahi, Aliki DT 92 Dunn Jr., Tommy Utah 11-Caldwell, Rock, 12-Simmons, Larry, 13-Bray, Daniel, 14-Hart, JC, 15-Holtzclaw, Lance, 15-Ficklin, Byrd, 17-Curtis, Dillon, 19-Caldarella, Luca, 20-Helu, Mateaki, 21-Rogers, NaQuari, 25-Duke, Bryce, 28-Carvalho, Mana, 29-Thompson, LaTristan, 3-Johnson, Nate, 3-Damuni, Levani, 30-Stokes Jr., Jason, 32Shah, Omar, 33-Lopes, Kana\u27i, 35-Polu, Cyrus, 36-Fonoimoana, Brock, 4-Saunders, Don, 44-Castor, Logan, 5-Tia, Otto, 51-Kaufusi, Karson, 64-Parmenter, Reece, 75-Alderman, Roger, 76-Williams, Zereoue, 79-Harrison, Alex, 83-Elliss, Elijah, 9-Davis, Elijah, 92-Phillips, Orion, 96-Tauteoli, Mike, 98-Vakalahi, Dallas Kansas 1-Henderson Jr., Emmanuel, 13-Cohoon, Bryce, 14-Dye, Jalen, 16-Brantley, Logan, 17-Hamm, Jaden, 20-Curvey, Malachi, 22-Gibbs, Syeed, 23-Ellis, Mason, 3-Sipp Jr., Joseph, 3-Kubecka, Keaton, 33-Harris III, Leroy, 35-Lappin, Finn, 37-Addison, Grayden, 39-Mondi, Cole, 4-Williams, Leshon, 41-Vedral, Ezra, 5Emilien, Doug, 51-Duggar, Emory, 54-Tuikolovatu, Tavake, 6-Hurley, Jahlil, 7-Pickett, Cam, 74-Tanner, Jack, 8-Marshall, Isaiah, 8-Kamara, Jon Jon, 80Moeller, Mack, 85-Nagy, Tate, 87-Cure, Leyton, 9-Brinkley, Dak, 91-Bray, Alex, 94-Herold, Blake, 96-Petrus, Cole, 99-Marjan, Laith Drive Chart report Utah vs Kansas (Nov 28, 2025) Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 UTAH Drive Started Team Qtr Spot Time UTAH 1st UTAH35 11:20 UTAH20 02:16 UTAH25 12:03 UTAH UTAH10 UTAH Drive Ended Consumed Spot Time How lost PI - Yds TOP Interception KU16 08:39 *FIELD GOAL 6 - 49 02:41 FieldGoalMissed UTAH25 01:00 Punt 3-5 01:16 Kickoff KU00 09:24 *TOUCHDOWN 6 - 75 02:39 06:00 Punt KU29 00:45 Downs 13 - 61 05:15 UTAH21 00:19 Punt UTAH23 00:00 End of half 1-2 00:19 UTAH35 15:00 Kickoff KU33 12:09 Downs 8 - 32 02:51 UTAH UTAH37 08:12 Kickoff UTAH42 08:02 Fumble 1-5 00:10 UTAH UTAH40 06:34 Downs KU47 05:08 Punt 4 - 13 01:26 UTAH20 13:39 Interception KU00 12:26 *TOUCHDOWN 4 - 80 01:13 UTAH UTAH15 05:28 Kickoff KU00 02:14 *TOUCHDOWN 8 - 85 03:14 UTAH KU16 01:52 Downs KU19 00:00 End of half 3 - -3 01:52 UTAH UTAH UTAH UTAH 2nd 3rd 4th Obtained Utah Q1 Q2 Q3 Q4 H1 H2 Total Time of possession 03:57 08:13 04:30 06:23 12:10 10:53 23:03 3rd down conversions 0-2 4-5 1-3 2-3 4-7 3-6 7-13 Average field position UTAH28 UTAH19 UTAH37 UTAH40 UTAH22 UTAH39 UTAH31 4th down conversions 0-0 0-1 0-1 0-0 0-1 0-1 0-2 KANSAS Drive Started Drive Ended Consumed Team Qtr Spot Time Obtained Spot Time How lost PI - Yds TOP KU 1st KU21 14:52 Kickoff UTAH25 11:20 Interception 8 - 54 03:32 KU KU25 08:39 Kickoff UTAH18 02:16 Missed FG 12 - 57 06:23 KU KU27 01:00 Punt UTAH00 12:03 *TOUCHDOWN 8 - 73 03:57 KU30 09:19 Kickoff KU45 06:00 Punt 5 - 15 03:19 KU29 00:45 Downs KU34 00:19 Punt 3-5 00:26 KU33 12:09 Downs UTAH00 08:15 *TOUCHDOWN 8 - 67 03:54 KU UTAH43 08:02 Fumble UTAH40 06:34 Downs 4-3 01:28 KU KU10 05:08 Punt UTAH12 13:39 Interception 11 - 78 06:29 KU24 12:19 Kickoff UTAH05 07:52 Interception 8 - 71 04:27 KU KU07 07:46 Kickoff UTAH00 05:32 *TOUCHDOWN 8 - 93 02:14 KU KU25 02:14 Kickoff KU16 01:52 Downs 4 - -9 00:22 KU 2nd KU KU KU 3rd 4th Kansas Q1 Q2 Q3 Q4 H1 H2 Total Time of possession 11:03 06:47 10:30 08:37 17:50 19:07 36:57 3rd down conversions 2-4 0-2 4-5 2-4 2-6 6-9 8-15 Average field position KU24 KU30 KU33 KU19 KU26 KU26 KU26 4th down conversions 0-0 0-0 0-1 0-1 0-0 0-2 0-2 Drive Chart By Quarter report Utah vs Kansas (Nov 28, 2025) Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 Drive Started Drive Ended Consumed Team Qtr Spot Time Obtained Spot Time How lost PI - Yds TOP KU 1st KU21 14:52 Kickoff UTAH25 11:20 Interception 8 - 54 03:32 UTAH UTAH35 11:20 Interception KU16 08:39 *FIELD GOAL 6 - 49 02:41 KU KU25 08:39 Kickoff UTAH18 02:16 Missed FG 12 - 57 06:23 UTAH UTAH20 02:16 FieldGoalMissed UTAH25 01:00 Punt 3-5 01:16 KU KU27 01:00 Punt UTAH00 12:03 *TOUCHDOWN 8 - 73 03:57 UTAH25 12:03 Kickoff KU00 09:24 *TOUCHDOWN 6 - 75 02:39 KU KU30 09:19 Kickoff KU45 06:00 Punt 5 - 15 03:19 UTAH UTAH10 06:00 Punt KU29 00:45 Downs 13 - 61 05:15 KU KU29 00:45 Downs KU34 00:19 Punt 3-5 00:26 UTAH UTAH21 00:19 Punt UTAH23 00:00 End of half 1-2 00:19 UTAH35 15:00 Kickoff KU33 12:09 Downs 8 - 32 02:51 KU KU33 12:09 Downs UTAH00 08:15 *TOUCHDOWN 8 - 67 03:54 UTAH UTAH37 08:12 Kickoff UTAH42 08:02 Fumble 1-5 00:10 KU UTAH43 08:02 Fumble UTAH40 06:34 Downs 4-3 01:28 UTAH UTAH40 06:34 Downs KU47 05:08 Punt 4 - 13 01:26 KU KU10 05:08 Punt UTAH12 13:39 Interception 11 - 78 06:29 UTAH20 13:39 Interception KU00 12:26 *TOUCHDOWN 4 - 80 01:13 KU KU24 12:19 Kickoff UTAH05 07:52 Interception 8 - 71 04:27 KU KU07 07:46 Kickoff UTAH00 05:32 *TOUCHDOWN 8 - 93 02:14 UTAH UTAH15 05:28 Kickoff KU00 02:14 *TOUCHDOWN 8 - 85 03:14 KU KU25 02:14 Kickoff KU16 01:52 Downs 4 - -9 00:22 UTAH KU16 01:52 Downs KU19 00:00 End of half 3 - -3 01:52 UTAH UTAH UTAH 2nd 3rd 4th Play By Play report Utah vs Kansas (Nov 28, 2025) Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 1st Quarter Kansas wins toss and will receive; UTA will defend South end-zone. (15:00) #17 D.Curtis kickoff 62 yards to the KU03 #1 E.Henderson Jr. return 18 yards to the KU21 (#37 T.Reynolds). Kansas drive starts at 14:52 1-10 KU21 (14:51) Shotgun #9 D.Hishaw Jr. rush middle for 5 yards gain to the KU26 (#93 K.Dillon). 2-5 KU26 (14:14) Shotgun #6 J.Daniels pass incomplete short left to #1 E.Henderson Jr. thrown to KU33. 3-5 KU26 (14:07) Shotgun #6 J.Daniels pass complete short middle to #7 C.Pickett caught at KU31, for 8 yards to the KU34 (#2 S.Snowden; #8 L.Barton), 1ST DOWN. 1-10 KU34 (13:33) No Huddle-Shotgun #6 J.Daniels rush middle for 15 yards gain to the KU49, End Of Play, 1ST DOWN. 1-10 KU49 (12:53) No Huddle-Shotgun #6 J.Daniels pass complete short left to #7 C.Pickett caught at KU49, for 25 yards to the UTAH26 (#23 J.Bennee), 1ST DOWN. 1-10 UTAH26 (12:10) No Huddle-Shotgun #6 J.Daniels pass complete short right to #7 C.Pickett caught at UTAH25, for 1 yard to the UTAH25 (#2 S.Snowden). 2-9 UTAH25 (11:32) Shotgun #6 J.Daniels pass incomplete deep right to #1 E.Henderson Jr. thrown to UTAH00 QB hurried by #0 L.Fano and #8 L.Barton. 3-9 UTAH25 (11:26) Shotgun #6 J.Daniels pass intercepted by #2 S.Snowden at UTAH18 #2 S.Snowden return 17 yards to the UTAH35, End Of Play. 8 plays, 54 yards, 03:32 Utah drive starts at 11:20 1-10 UTAH35 (11:18) Shotgun #1 W.Parker rush left for 34 yards gain to the KU31 (#2 L.Rawls; #0 A.Alexander), 1ST DOWN. 1-10 KU31 (10:53) No Huddle-Shotgun #1 W.Parker rush left for 15 yards gain to the KU16 (#4 T.Lathan), out of bounds, 1ST DOWN. 1-10 KU16 (10:32) No Huddle-Shotgun #1 W.Parker rush right for 7 yards gain to the KU09 (#5 D.Miller; #11 D.Dye). 2-3 KU09 (09:52) Shotgun #1 W.Parker rush middle for 0 yards to the KU09 (#92 T.Dunn Jr.). 3-3 KU09 (09:16) Shotgun Utah rush middle for 7 yards loss to the KU16 fumbled by Utah at KU16 recovered by UTAH #4 D.Dampier at KU16, End Of Play. 4-10 KU16 (08:39) #17 D.Curtis field goal attempt from 34 yards GOOD (H: #92 O.Phillips, LS: #44 L.Castor), clock 08:39. Utah 3, Kansas 0. 6 plays, 49 yards, 02:41 (08:39) #17 D.Curtis kickoff 65 yards to the KU00, Touchback. Kansas drive starts at 08:39 1-10 KU25 (08:36) Shotgun #8 I.Marshall rush middle for 13 yards gain to the KU38 (#3 L.Damuni), 1ST DOWN. 1-10 KU38 (08:08) Shotgun #6 J.Daniels rush right for 2 yards loss to the KU36 (#7 J.Hall). 2-12 KU36 (07:23) Shotgun #4 L.Williams rush middle for 6 yards gain to the KU42 (#5 T.Johnson; #3 L.Damuni). 3-6 KU42 (06:42) Shotgun #9 D.Hishaw Jr. rush right for 7 yards gain to the KU49 (#5 T.Johnson), 1ST DOWN. 1-10 KU49 (06:07) Shotgun #4 L.Williams rush middle for 9 yards gain to the UTAH42 (#7 J.Hall; #23 J.Bennee). 2-1 UTAH42 (05:32) Shotgun #4 L.Williams rush left for 13 yards gain to the UTAH29 (#23 J.Bennee), 1ST DOWN. 1-10 UTAH29 (04:53) Shotgun #1 E.Henderson Jr. rush right for 9 yards gain to the UTAH20 (#8 L.Barton). 2-1 UTAH20 (04:19) Shotgun #9 D.Hishaw Jr. rush middle for 7 yards gain to the UTAH13 (#91 J.Lea\u27ea), 1ST DOWN. 1-10 UTAH13 (03:46) Shotgun #4 L.Williams rush middle for 2 yards gain to the UTAH11 (#15 L.Holtzclaw). 2-8 UTAH11 (03:02) Shotgun #9 D.Hishaw Jr. rush right for 2 yards loss to the UTAH13 (#0 L.Fano). 3-10 UTAH13 (02:23) Shotgun #6 J.Daniels pass incomplete short right to #3 K.Kubecka thrown to UTAH00 broken up by #5 T.Johnson. 4-10 UTAH13 (02:19) PENALTY KU False Start (#77 E.Cruz Jr.) 5 yards from UTAH13 to UTAH18. NO PLAY. 4-15 UTAH18 (02:19) #99 L.Marjan field goal attempt from 36 yards NO GOOD (H: #37 G.Addison, LS: #51 E.Duggar), clock 02:16. 12 plays, 57 yards, 06:23 Utah drive starts at 02:16 1-10 UTAH20 (02:14) Shotgun #15 B.Ficklin rush right for 2 yards gain to the UTAH22 (#2 L.Rawls). 2-8 UTAH22 (01:48) No Huddle-Shotgun #4 D.Dampier pass incomplete short left to #12 L.Simmons thrown to UTAH24 broken up by #33 L.Harris III. 3-8 UTAH22 (01:44) Shotgun #4 D.Dampier rush middle for 3 yards gain to the UTAH25 (#94 B.Herold). 4-5 UTAH25 (01:05) #92 O.Phillips punt 48 yards to the KU27 fair catch by #85 T.Nagy at KU27. 3 plays, 5 yards, 01:16 Kansas drive starts at 01:00 1-10 KU27 (00:59) Shotgun #8 I.Marshall rush right for 8 yards gain to the KU35 (#5 T.Johnson), out of bounds. 2-2 KU35 (00:23) Shotgun #9 D.Hishaw Jr. rush middle for 3 yards gain to the KU38 (#0 L.Fano), 1ST DOWN. Summary Utah Kansas Score 3 0 Time Poss 03:57 11:03 R 2 6 1st Downs P X 0 0 2 0 T 2 8 Conversions 3rd 4td 0-2 0-0 2-4 0-0 Rushing 7-54 14-93 Passing 0-1-0-0 3-7-1-34 P1 R2 P3 R1 R2 R4 R5 R6 R7 R8 Penalties 0-0 1-5 Quickie report Utah vs Kansas (Nov 28, 2025) Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 FIRST QUARTER UTAH KU Score 3 0 FIRST DOWNS 2 8 RUSHES-YARDS (NET) 7-54 14-93 PASSING YDS (NET) 0 34 Passes Cmp-Att-Int 0-1-0 3-7-1 TOTAL OFFENSE PLAYS-YARDS 8-54 21-127 Fumble Returns-Yards 0-0 0-0 Punt Returns-Yards 0-0 0-0 Kickoff Returns-Yards 0-0 1-18 Interception Returns-Yards 1-17 0-0 Punts (Number-Avg) 1-48.0 0-0.0 Fumbles-Lost 1-0 0-0 Penalties-Yards 0-0 1-5 Possession Time 03:57 11:03 Third-Down Conversions 0 of 2 2 of 4 Fourth-Down Conversions 0 of 0 0 of 0 Red-Zone Scores-Chances 1-1 1-2 UTAH KANSAS Rushing No. Gain Loss Net TD Lg Avg Rushing No. Gain Loss Net TD Lg Wayshawn Parker 4 56 0 56 0 34 14.0 Leshon Williams 4 30 0 30 0 13 7.5 Devon Dampier 1 3 0 3 0 3 3.0 Isaiah Marshall 2 21 0 21 0 13 10.5 Byrd Ficklin 1 2 0 2 0 2 2.0 Daniel Hishaw Jr. 5 22 2 20 0 7 4.0 TEAM 1 0 7 -7 0 0 -7.0 Jalon Daniels 2 15 2 13 0 15 Passing C-A-I Passing C-A-I Yds TD 0 0 Long Sack TD Long 6.5 Sack Devon Dampier 0-1-0 0 Jalon Daniels 3-7-1 34 0 Receiving TAR No. Yards YAC TD Long Receiving TAR No. Yards YAC TD Long 1 0 0 0 0 0 Cam Pickett 4 3 34 28 0 25 Emmanuel Henderson Jr. 2 0 0 0 0 0 Keaton Kubecka 1 0 0 0 0 0 Yds Avg Long In20 TB Yards Larry Simmons 0 Yds Avg Punting No. Yds Avg Long In20 TB Orion Phillips 1 48 48.0 48 0 0 Punt Returns No. Yards TD Kick Returns No. Yards TD 25 0 Punting No. Long Punt Returns No. TD Long Long Kick Returns No. Yards TD Long Emmanuel Henderson Jr. 1 18 0 18 Tackles UA-A Total Sacks TFL Tackles UA-A Total Sacks TFL Jackson Bennee 2-1 3 0.0 0.0 Lyrik Rawls 1-1 2 0.0 0.0 Tao Johnson 2-1 3 0.0 0.0 Austin Alexander 0-1 1 0.0 0.0 Johnathan Hall 1-1 2 0.0 1.0 Blake Herold 1-0 1 0.0 0.0 Lander Barton 1-1 2 0.0 0.0 Dean Miller 0-1 1 0.0 0.0 Qtr Time Scoring Play 1st 08:39 UTAH - #17 D.Curtis 34 yd FG, 6-49, 02:41 V-H 3-0 Play By Play report Utah vs Kansas (Nov 28, 2025) 1-10 KU38 Date: Nov 28, 2025 Site: Lawrence, Kansas Stadium: David Booth Kansas Memorial Stadium Attendance: 32811 2nd Quarter (14:59) Shotgun #6 J.Daniels pass incomplete deep middle to #11 B.Canty thrown to UTAH16 PENALTY UTAH Pass Interference (#5 T.Johnson) 15 yards from KU38 to UTAH47, 1ST DOWN. NO PLAY. 1-10 UTAH47 (14:48) Shotgun #6 J.Daniels rush middle for 3 yards gain to the UTAH44 (#7 J.Hall). 2-7 UTAH44 (14:17) Shotgun #6 J.Daniels rush left for 7 yards gain to the UTAH37 (#93 K.Dillon), out of bounds, 1ST DOWN, PENALTY UTAH Personal Foul (#93 K.Dillon) 15 yards from UTAH37 to UTAH22, 1ST DOWN. 1-10 UTAH22 (14:00) Shotgun #9 D.Hishaw Jr. rush middle for 8 yards gain to the UTAH14 (#0 L.Fano; #5 T.Johnson). 2-2 UTAH14 (13:15) Shotgun #4 L.Williams rush middle for 6 yards gain to the UTAH08 (#8 L.Barton; #37 T.Reynolds), 1ST DOWN. 1-G UTAH08 (12:40) Shotgun #9 D.Hishaw Jr. rush right for 1 yard gain to the UTAH07 (#23 J.Bennee). 2-G UTAH07 (12:05) Shotgun #9 D.Hishaw Jr. rush right for 7 yards gain to the UTAH00 TOUCHDOWN, clock 12:03. UTAH03 #99 L.Marjan kick attempt good (H: #37 G.Addison, LS: #51 E.Duggar). Utah 3, Kansas 7. 8 plays, 73 yards, 03:57 (12:03) #99 L.Marjan kickoff 65 yards to the UTAH00, Touchback. Utah drive starts at 12:03 1-10 UTAH25 (12:00) Shotgun #4 D.Dampier pass complete short right
#10 Texas A&M vs. #21 University of Utah; Sept. 4, 2025
No full textVolleyball meet results, scoresAttendance: 1651; Head coach: Beth LauniereWomen\u27s VolleyballTexas A&M 3 (25, 25, 25); Utah 0 (19, 23, 18)Texas A&M (4-0,0-0 SEC) -vs- Utah (3-1,0-0 Big 12) 9/4/2025 at Salt Lake City, UT (Jon M. Huntsman Center) Site: Salt Lake City, UT (Jon M. Huntsman Center) Date: 9/4/2025 Attendance: 1,651 Time: 6:02 pm Officials: Set Scores Texas A&M (3) Utah (0) 1 25 19 2 25 23 3 25 18 Texas A&M (4-0,0-0 SEC) # 9 1 12 16 4 21 3 37 2 TM 11 14 Player Lednicky, Logan Cos-Okpalla, Ifenna Underwood, Ava Waak, Maddie Hellmuth, Emily Perkins, Morgan Thomas, Tatum Stowers, Kyndal Applegate, Addi TEAM Humphrey, Taylor Musgrove, Kirra Totals Set 1 2 3 K 13 20 17 50 SP 3 3 3 3 3 3 3 3 3 3 2 2 34 Attack K 17 3 0 0 12 5 0 11 0 0 2 0 50 E 6 6 11 23 E 6 2 0 2 7 0 0 6 0 0 0 0 23 TA 31 6 0 5 30 6 0 25 0 0 3 0 106 TA 31 36 39 106 PCT .355 .167 0 -.400 .167 .833 0 .200 0 0 .667 0 .255 Set A 1 0 4 43 0 0 0 0 0 0 0 1 49 E 0 0 0 0 0 0 0 0 0 0 0 0 0 Serve SA 0 0 0 4 0 0 0 0 0 0 0 0 4 SE 0 1 0 0 0 0 1 0 1 0 0 0 3 Block BS 0 1 0 0 0 0 0 0 0 0 0 0 1 BA 1 3 0 0 1 1 0 2 0 0 0 0 8 BE 0 1 0 0 0 0 0 0 0 0 0 0 1 Defense DIG 5 3 10 5 2 0 2 11 4 0 0 0 42 BHE 0 0 0 0 0 0 0 0 0 0 0 0 0 Rec RE 0 0 0 0 0 1 0 0 1 0 0 0 2 PTS 17.5 5.5 0.0 4.0 12.5 5.5 0.0 12.0 0.0 0.0 2.0 0.0 59.0 Set A 1 1 1 0 27 0 0 0 0 0 30 E 0 0 0 0 1 0 0 0 0 0 1 Serve SA 1 0 0 0 0 0 0 1 0 0 2 SE 1 2 0 2 2 0 0 2 0 0 9 Block BS 0 0 0 0 1 0 1 0 0 0 2 BA 5 1 2 0 2 2 2 0 0 0 14 BE 0 0 1 0 0 0 0 0 0 0 1 Defense DIG 1 10 5 1 1 1 0 4 0 0 23 BHE 0 0 0 0 0 0 0 0 0 0 0 Rec RE 0 4 0 0 0 0 0 0 0 0 4 PTS 7.5 12.5 8.0 0.0 4.0 4.0 6.0 1.0 0.0 0.0 43.0 % 0.226 0.389 0.154 .255 Utah (3-1,0-0 Big 12) # 2 18 20 10 3 12 17 11 TM 5 Player Moea\u27i, Emrie Gibadlo, Kamryn Joki, Neea-Maria Key-Powell, Levani Marco, Isabelle Field, Katelynn Grossenbach, Allie Payne, McKenna TEAM Wilton-LaBoy, Leah Totals Set 1 2 3 SP 3 3 3 3 3 3 3 3 3 1 28 K 10 15 7 32 E 7 2 2 11 Attack K 4 12 7 0 2 3 4 0 0 0 32 E 4 4 1 0 0 0 2 0 0 0 11 TA 31 29 29 89 TA 18 36 19 0 3 5 8 0 0 0 89 PCT .000 .222 .316 0 .667 .600 .250 0 0 0 .236 % 0.097 0.448 0.172 .236 Tie scores Lead changes 1 1 0 2 9 3 3 6 2 Total 16
Oral History Interview with Dr. Glen Fifield, February 10, 2025
No full textThe interview with Dr. Glen Fifield, a 95-year-old retired music educator, details his musical career and his immense contribution to the music program in Carbon County, Utah. Starting with his father\u27s cornet, his passion led to serious music study and a teaching career that saw him and woodwind specialist Derral Siggard build a celebrated band program in Price, which was invited to march in the Rose Parade. They developed the Master Musician program to motivate students to achieve individual excellence. During his time in Price, Fifield also played trumpet in the legendary Jimmy Dart Orchestra, a big band dance group that performed across the state. He later taught at the College of Eastern Utah and finished his career at Utah State University. Dr. Fifield praised the vital contributions of Janis Siggard, who served as a tremendous musician and accompanist for hundreds of student solos. He and Derral Siggard consciously worked to uphold the musical tradition established by earlier educator E.M. Williams, proudly referring to their group as A Band With a Heritage
Saccadic Intrusions and Nystagmus in Cerebellar Ataxia
No full textThis patient demonstrates 4 common types of intrusions/nystagmus that may be seen in cerebellar ataxia: 1) square wave jerks (SWJ, a saccadic intrusion), 2) downbeat nystagmus (seen minimally in primary gaze, mainly in lateral gaze), 3) gaze-evoked nystagmus, 4) rebound nystagmus. The presence of SWJ can make it more challenging to diagnose nystagmus, but the presence of downbeat, gaze-evoked and rebound nystagmus is highly suggestive of cerebellar flocculus/paraflocculus dysfunction
Fresh Life Church [03]
No full textAddress: 320 East 200 South, Salt Lake City, UT. Local branch of a church founded in 2007 in Kalispell, Montana, by Levi and Jennie Lusko, this evangelical congregation has met at various rented venues, including the Infinity Center in 2019 (see photos in the Salt Lake City Religious Architecture Photo collection)
Grace Baptist Church, West Valley City [03]
No full textAddress: 4737 West 4100 South, WVC, UT. Affiliated with the Salt Lake Baptist Association (Southern Baptist Convention). A sign outside reads, "Iglesia Bautista Gracia Eterna," the Spanish-speaking equivalent. The congregation began as Western Hills Baptist Church in Magna, and in 1982 moved to rented space in West Valley City, to 4880 W. 4100 South in 1985. A new church building was constructed a few blocks east on 4100 South, and the congregation moved in in September of 2007
Our Lady of Perpetual Help Catholic Church [07]
No full textAddress: 4360 West 5415 South, Kearns, UT. This parish is focused on the Vietnamese community. They purchased the former Kearns Ward LDS meetinghouse in 2003, and added a bell tower with a cross. Part of the building was originally the chapel for the Kearns Air Force Base, moved to the present site after World War II