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Treatment of lung disease in alpha-1 antitrypsin deficiency: a systematic review - Supplementary Material
Research data used in the paper 'Treatment of lung disease in alpha-1 antitrypsin deficiency: a systematic review.', Edgar RG, Patel M, Bayliss S, Crossley D, Sapey E, Turner AM, forthcoming in The International Journal of Chronic Obstructive Pulmonary Disease (2017
Fibre-feed tests at Izana in 2017 September
The new fibre-based spectrometer was updated from 2017 September 1 to 11. The detector electronic noise and atmospheric scintillation noise were both measured. The scintillation noise was found to be approximately 105 times higher than the electronic noise, and so the system is dominated by atmospheric noise. It is unlikely that the LCD-based system switching polarisation states at 5 Hz will be able to equal the performance of a typical Pockel’s-cell-based system switching at 100 Hz. An overall reduction in noise power by a factor of almost 5 times is required to match the performance of Fred in Sutherland. This difference is of the order difference in scintillation noise between 5 Hz switching and 100 Hz switching.
Two fibre-feeds were trialled. A 30 mm focal length lens to replace the exiting 80 mm, and so focusing a smaller image of the Sun onto the end of the fibre, and a telescope arrangement coupling quasi-parallel light into the fibre. The shorter focal length lens resolves both the low- and high-frequency issues experienced since initial commissioning. The quasi-parallel telescope fibre-feed suffers some Doppler-imaging problems and also produces higher noise levels due to the lower light throughput.
The primary cœlostat mirror was replaced, and resulted in an increase in counts for Mark-I by approximately 3%. The PMT HV-PSU was replaced, removing a temporary 2kV unit and reinstating the normal 3kV supply resulting in a further increase in counts for Mark-I by approximately 18%
Mount controller repairs at Las Campanas in 2017 November
Problems with the mount encoder position values and the RA drive were investigated and found to be caused by corrosion around the encoder header connectors on the PCB, and general dirt brought in by the cooling fan. The mount controller and RA motor were replaced with spares from Birmingham, resolving all faults. The delta-B module was decommissioned
Renewables, Investments, and State Aids: Exploring the Legal Side of Polycentricity
The requirement to adopt minimum labour standards is now standard practice in free trade agreements negotiated by major trading powers such as the EU and US. However, such practice has historically been contested by developing countries, who contend that the requirement to increase labour and social protection standards is designed to remove one of the few competitive advantages that developing countries have over developed countries in attracting foreign investment. More recently, the EU and the US have also sought to use so-called ‘mega-regionals’ to promote labour standards. This was a significant development in that their proponents were keen to stress that these agreements would set the benchmark for labour protection provisions in FTAs, readily admitting that one of the central aims pursued by such agreements was to redefine the rules of the global trading system. The paper aims to assess the labour standards provisions included in EU and US FTAs, determine the rationale behind the inclusion of such provisions, and examine the extent to which mega-regionals such as the TTIP and the TPP marked a significant departure from past practice
Testing for Panel Cointegration using Common Correlated Effects Estimators
Spurious regression analysis in panel data when the time series are cross-section dependent is analyzed in the paper. We show that consistent estimation of the long-run average parameter is possible once we control for cross-section dependence using cross-section averages in the spirit of the common correlated effects approach in Pesaran (2006). This result is used to design a panel cointegration test statistic accounting for cross-section dependence. The performance of the proposal is investigated in comparison with factor-based methods to control for cross-section dependence when strong, semi-weak and weak cross-section dependence may be present
Next Generation Infrastructure Interdependencies: An economic deterministic model of transport interdependencies in the United Kingdom
The role of infrastructure interdependencies is challenging due to the complexity and dynamic environment of all infrastructures and vital for critical infrastructure systems. There is an ongoing debate about the value of the benefits of the five national infrastructure sectors (energy, water, transport, waste and communication) in the UK and how they interact in terms of social, economic and environmental wellbeing , . This study focuses only on one of the three aforementioned values, the economic value. The hypothesis tested is whether the transport sector is economically complemented by the energy, water and waste sectors and economically substituted by the communication sector1. The authors use the process analysis “networks and cohorts”, an analysis that uses tables, diagrams, models and networks of interactions along with organizational linkages . Of interest for this study in particular is the grand total of all revenues (capital value) which create incomes into other sectors and creates dependencies. This, by definition, is the Gross Value Added. The last five symmetric (product by product) Input-Output tables of gross value added are used: 2010, 2005, 1995, 1990 and 1984 . The theory underpinning the hypothesis was verified and one mathematical equation was developed based on the historical data of the gross value added by the value created in millions of pounds (£m) from the other critical sectors to transport
Valuing Transport Infrastructure: A quantitative study of the factors defining the social value of transport infrastructure in the UK
Infrastructure Interdependencies: Transport sector economic dependency with other critical infrastructure sectors in the UK
‘For now we see through a glass, darkly’: examining diversity disclosures by UK law firms through a critical race perspective.
This paper critically explores an initiative by the Legal Services Board to create data sets for easier identification of inequalities in gender, race and class. It examines its origins and development;evaluates its scope and effectiveness; and considers the LSB diversity reporting rule as the first step in addressing issues of inequality, notwithstanding its over-reliance on numbers