Journal of Science and Application Technology (JSAT - Institut Teknologi Sumatera)
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Analysis of Vitamin A Content and Antioxidant Test in Super and Bulk Olein
Full text link Cooking oil is the essential food for bodies. Cooking oil should be enriched with vitamin A because this substance plays a critical role in maintaining health. Cooking oil contains antioxidant compounds, which inhibit or slow down oxidation reactions. This study aimed to determine the amount of vitamin A in super olein and bulk olein before fortification and the amount of antioxidant content in super olein and bulk olein before fortification. The amount of vitamin A content was obtained using the High-Performance Liquid Chromatography (HPLC) method of <0.005 IU/gram, while the antioxidant test results were carried out by the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method using UltraViolet-Visible Spectrophotometry (UV-Vis). The resulting antioxidant activity has an inhibition value of 23% and 10% in bulk and super olein, respectively. Cooking oil is the essential food for bodies. Cooking oil should be enriched with vitamin A because this substance plays a critical role in maintaining health. Cooking oil contains antioxidant compounds, which inhibit or slow down oxidation reactions. This study aimed to determine the amount of vitamin A in super olein and bulk olein before fortification and the amount of antioxidant content in super olein and bulk olein before fortification. The amount of vitamin A content was obtained using the High-Performance Liquid Chromatography (HPLC) method of <0.005 IU/gram, while the antioxidant test results were carried out by the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method using UltraViolet-Visible Spectrophotometry (UV-Vis). The resulting antioxidant activity has an inhibition value of 23% and 10% in bulk and super olein, respectively
Caffeine Molecular Target Identification and Protein Interaction Analysis in Alzheimer's Disease
Full text linkCaffeine is known to have various biological effects, including its potential to modulate the central nervous system. This study aims to identify the molecular targets of caffeine and explore their relationship with Alzheimer's disease using a bioinformatics approach. The methods used include target prediction using SwissTargetPrediction and SuperPred, target relationship analysis with disease through the DAVID database, protein interaction exploration and enrichment analysis using STRING-DB, and network analysis using Cytoscape. The results showed that from the total targets obtained, there were 20 overlapping targets related to Alzheimer's. Protein interaction analysis revealed 17 nodes with 32 significant interactions, which provide insight into the molecular pathways that caffeine can manipulate in the context of neuroprotection. These findings are in line with various studies showing that caffeine consumption is associated with a reduced risk of Alzheimer's through modulation of the nervous system and inflammation
Faktor-faktor yang berhubungan dengan eksaserbasi pada pasien penyakit paru obstruksi kronik (PPOK) di RSUD dr. H. Abdul Moeloek
Full text linkPenyakit Paru Obstruktif Kronik (PPOK) adalah penyakit paru kronik dengan gejala seperti sesak napas, batuk, dan produksi sputum yang bisa mengalami perburukan atau eksaserbasi. Identifikasi faktor risiko eksaserbasi PPOK penting untuk strategi pencegahan. Penelitian ini bertujuan menentukan prevalensi, karakteristik, dan faktor-faktor yang berkaitan dengan eksaserbasi. Penelitian ini merupakan penelitian non-eksperimental dengan desain penelitian cross-sectional. Pengambilan sampel menggunakan teknik total sampling pada 90 pasien PPOK yang menjalani rawat inap di RSUD Dr. H. Abdul Moeloek yang memenuhi kriteria inklusi (pasien diagnosis PPOK/kode ICD J44 yang melakukan pengobatan rawat inap periode Juni-Agustus 2023; usia ≥40 tahun) dan eksklusi (rekam medis yang tidak dapat terbaca dan tidak lengkap). Pengambilan sampel dilakukan dengan metode total sampling. Data sekunder berupa rekam medik dianalisis secara statistik menggunakan uji Chi-square dan regresi logistik. Hasil penelitian menunjukkan prevalensi eksaserbasi PPOK sebesar 58%. Karakteristik pasien PPOK yaitu berjenis kelamin laki-laki (79%), usia >60 tahun (56%), perokok (62%), memiliki komorbid (95%), tidak mengalami eksaserbasi dalam satu tahun terakhir (62%), dan tidak ada riwayat penggunaan kortikosteroid sistemik (53%). Variabel status merokok (p=0,002) dan riwayat eksaserbasi sebelumnya (p=0,035) menjadi dua dari lima variabel yang menunjukkan hubungan signifikan dalam analisis bivariat. Analisis multivariat menunjukkan status merokok sebagai faktor paling berhubungan dengan eksaserbasi PPOK (p=0,003; OR=12,137; 95% CI=2,312-63,714). Berdasarkan hasil penelitian, faktor risiko eksaserbasi PPOK mencakup status merokok dan riwayat eksaserbasi dalam satu tahun terakhir, dengan status merokok merupakan faktor yang paling berhubungan terhadap kejadian eksaserbasi PPOK.  
Calculation of The Chain Ladder and Bornhoutter-Ferguson Methods in Calculating Claim Reserves for Insurance of Property Company in Sumatra
Full text linkProperty insurance provides financial protection against the risk of loss due to damage or loss of insured property, such as buildings, vehicles, and equipment. Property insurance companies are required to maintain sufficient reserves to meet future claim obligations. Therefore, these companies need to accurately estimate claim reserves. This study aims to compare two methods of estimating property insurance claim reserves Chain Ladder method and Bornhuetter-Ferguson method. The data used in this research is secondary data obtained from property insurance in Sumatra, covering production and claims data from 2018 to 2023. The Chain Ladder method is a straightforward approach that uses historical claims development patterns to project future claims. The Bornhuetter-Ferguson method combines information from paid claims and estimates of the loss ratio from earned premium to predict reserves. Both methods are compared to assess their accuracy in estimating claim reserves using the Mean Absolute Percentage Error (MAPE). The results of this study indicate that the Bornhuetter-Ferguson method provides better estimates of claim reserves compared to the Chain Ladder method
Dampak Konversi Lahan Pada Daerah Peri-Urban Terhadap Perubahan Mata Pencaharian Petani Tahun 2004-2024: Studi Kasus Desa Gentan, Baki, Sukoharjo
Full text linkLand conversion is a phenomenon of land conversion that causes a decrease in the proportion of a land area to other functions. In peri-urban areas that are dominated by agricultural land, its function changes to non-agricultural land due to land conversion for the construction of public facilities for the community. Especially at the location of this research study located in Gentan Village, Baki District, Sukoharjo Regency, Central Java. The existence of land conversion causes the loss of productive agricultural land so that farmers experience decreased productivity and affects farmers' livelihoods which change from agriculture to non-agriculture such as opening boarding houses, rental houses, shops, stalls and so on. This study uses a deductive quantitative approach with GIS analysis, Likert scale and Wilcoxon test to determine changes in farmers' livelihoods due to agricultural land conversion as the purpose of the study. The use of the snowball sampling technique with a quota of 32 farmers whose land was converted is based on the limitations of secondary data in the search for respondents. So that from this study it was found that land conversion causes significant changes in livelihoods that can affect socio-economic and environmental conditions
KARAKTERISTIK FISIKOKIMIA TEH DAUN SIRSAK (Annona muricata Linn.) DENGAN VARIASI SUHU DAN WAKTU PELAYUAN
Full text linkAbstract: Daun sirsak (Annona muricata Linn.) merupakan tumbuhan yang dapat dipergunakan menjadi alternatif minuman fungsional berupa teh yang mengandung senyawa antioksidan yang relatif tinggi. Penelitian ini bertujuan untuk mengetahui pengaruh suhu dan waktu pelayuan terhadap kualitas teh daun sirsak. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari dua variabel yaitu suhu pelayuan (80 dan 90˚C) dan lama pelayuan (2 dan 3 menit). Analisis produk meliputi kadar air, kadar abu, nilai pH, nilai rendemen, kadar polifenol, dan evaluasi hedonik (rasa, warna, aroma). Analisis data menggunakan ANOVA disertai dengan uji lanjut Duncan pada selang kepercayaan 95%. Hasil penelitian menunjukkan bahwa semakin meningkatnya suhu pelayuan maka akan menurunkan kadar air, kadar abu dan nilai rendemen serta meningkatkan kadar polifenol teh daun sirsak, Semakin lama waktu pelayuan maka akan menurunkan kadar air, kadar abu dan nilai rendemen serta meningkatkan nilai pH dan kadar polifenol teh daun sirsak, sedangkan interaksi antara suhu dan waktu pelayuan menurunkan kadar air, kadar abu dan nilai rendemen serta meningkatkan nilai pH teh daun sirsak. Proses pelayuan daun tidak berdampak pada uji hedoni teh daun sirsak. Hasil analisis menjelaskan bahwa produk teh daun sirsak yang terpilih adalah A2B2 (90˚C suhu pelayan dan 3 menit waktu pelayuan) dengan kadar air 4,060%, kadar abu 6,370%, nilai pH 6,46, nilai rendemen 32,010%, dan kadar polifenol 22,54%. Hasil uji hedonik menunjukkan bahwa variasi suhu dan lama pelayuan tidak mempengaruhi nilai kesukaan (aroma, warna, dan rasa).
Keywords: Daun Sirsak, Pelayuan, Polifenol, Teh.
Abstract: Soursop leaves (Annona muricata Linn.) have been identified as a potential functional beverage ingredient due to their high antioxidant content. This analysis aims to determine the effect of temperature and aging time on the quality of soursop leaf tea. To this end, a Completely Randomized Design (CRD) was employed, encompassing two variables: temperature (80 and 90°C) and time (2 and 3 minutes). The product analysis encompassed a comprehensive array of parameters, including moisture content, ash content, pH value, yield value, polyphenol content, and hedonic evaluation (taste, color, aroma). The collected data underwent analysis using a one-way analysis of variance (ANOVA) followed by Duncan's further test at 95% confidence interval. The results indicated that the variation in temperature led to a decrease in water content, ash content, and yield value, and an increase in polyphenol content of soursop leaf tea. Conversely, the variation in aging time resulted in a decrease in water content, ash content, and yield value, and an increase in pH value and polyphenol content of soursop leaf tea. Additionally, the interaction between temperature and aging time led to a decrease in water content, ash content, and yield value, and an increase in pH value of soursop leaf tea. The leaf-rotting process exerted no influence on the hedonic evaluation of soursop leaf tea. The analysis yielded the following results: the selected soursop leaf tea product was A2B2 (90°C and 3 minutes) with a moisture content of 4.060%, ash content of 6.370%, pH value of 6.46, yield value of 32.010%, and polyphenol content of 22.54%. The hedonic test results indicated that variations in temperature and aging time did not have a significant impact on the product's favorability value.
Keywords: Polyphenols, Soursop Leaves, Tea, Witherin
FORMULATION AND EVALUATION OF SACHA INCHI OIL-BASED SERUM AS AN ANTI-AGING COSMETIC
Full text linkSkin aging is a complex biological process influenced by intrinsic factors (genetic, hormonal, and metabolic) and extrinsic factors (UV exposure, pollution, and lifestyle), characterized by decreased collagen and elastin production and increased oxidative stress. Sacha Inchi seed oil is known for its high content of polyunsaturated fatty acids and bioactive compounds such as tocopherols and phenolics, which exhibit antioxidant activity beneficial to skin health. This study aimed to formulate and evaluate the physical stability of a facial serum containing Sacha Inchi seed oil (Plukenetia volubilis L.) as a natural anti-aging agent. The formulation was assessed through physical quality tests, including organoleptic properties, homogeneity, spreadability, viscosity, pH, and a cycling stability test over six cycles at 4°C and 40°C to simulate extreme storage conditions. The results showed that the serum maintained its physical stability after the cycling test. No significant changes were observed in organoleptic properties (color, odor, texture), and the formulation remained homogeneous with no phase separation. Viscosity slightly decreased from 3920 to 3643 mPa·s, while spreadability decreased from 13.6 to 9.4 g·cm/s, yet both remained within acceptable cosmetic limits. The pH remained stable between 5.44 and 5.47, aligning with the physiological skin pH range (4.5–6.5). These findings indicate that Sacha Inchi oil can be effectively formulated into a physically stable serum and holds promise for development as a natural active ingredient in anti-aging skincare products
Mathematical modeling of fixed and declining amortization schemes in cooperative loan systems
No full textVillage cooperatives play a pivotal role in promoting rural economic development by providing accessible microfinance services. This study evaluates two widely applied loan amortization schemes—fixed installment (annuity) and declining balance—within the framework of cooperative finance. By simulating a 12-month loan of IDR 10,000,000 at a 1% monthly interest rate, the paper models and examines the allocation of principal and interest payments under both approaches. The results indicate that although fixed installments ensure stable monthly obligations, they generate higher cumulative interest costs compared to declining balance schemes, which more closely align repayment amounts with the outstanding loan balance. A sensitivity analysis of varying interest rates and loan tenors further offers insights into financial risk management and borrower affordability. These findings can help cooperative managers develop more effective and transparent lending strategies
Western Lampung Offshore Wind and Wave Data Correlation Analysis
Full text linkWind and waves are the two most dominant environmental parameters in the sea. The availability of these two data is crucial in the design process of offshore and onshore buildings and the development of renewable energy from wind or wave. Numerous analyses have been done on each parameter, but none have tested their correlation specifically in the waters of the western Lampung. This study aims to find a correlation between these two parameters. The study used 20 years of wind and wave data from BMKG. The average wind speed data obtained was about 4,17 - 5,13 m/s. The mean significant wave height obtained was about 1,89 - 2,09 m. BMKG gives more direction with a huge wind-blowing duration (more than 500 hours), wind-blowing direction data are dominantly from SSE, WNW, and WSW. However, wave direction data is going to N and NE. This study found no correlation between wind and wave direction on the Western Lampung Offshore. Based on data from the time series of wind and wave that have been analyzed, continuously higher wind speeds result in higher wave heights
ANALISIS CEMARAN MIKROBIOLOGI DAN KARAKTERISTIK KIMIA DIMSUM AYAM DI KECAMATAN WAY HALIM KOTA BANDAR LAMPUNG
Full text linkDimsum is a popular snack made from chicken wrapped in wheat flour dough and cooked by steaming. It is favored by many due to its delicious taste and affordable price. However, dimsum sold by street vendors often lacks proper hygiene during processing and presentation, making it prone to microbial contamination. Chicken, as the main ingredient, is high in protein, which supports microbial growth. Contamination of microorganisms in food poses health risks to consumers. This study aims to analyze Total Plate Count (ALT) and Salmonella contamination and examine the correlation between chemical characteristics, such as water content and pH, and microbiological growth in chicken dimsum sold by five vendors in Way Halim District, Bandar Lampung City. The microbiological and chemical data were analyzed descriptively, and Pearson Correlation was used to determine the relationship between chemical characteristics and microbial growth. The results showed that all chicken dimsum samples exceeded the maximum ALT limit, and two samples tested positive for Salmonella. Referring to SNI 7756:2013, the standard for siomay quality and safety is a maximum ALT of 5×104 CFU/g and negative/25 g for Salmonella. The correlation test indicated that water content and pH had a significant relationship with ALT growth. The chicken dimsum sample with the highest ALT was the DC sample (6.31 log CFU/g), while the lowest was the DA sample (5.35 log CFU/g). Salmonella contamination was found in the DC and DE samples