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Effects of biomacromolecules on growth, digestibility, digestive enzyme activity, antioxidation, and immunity in broilers
No full textThis study aimed to evaluate the effects of two biomacromolecules, fermented wheat bran polysaccharides (FWBPs) and sodium humate (SH), on growth performance, nutrient digestibility, digestive enzyme activity, antioxidant status, and immunity of broilers. A total of 144 male, one-day-old Arbor Acres broilers were randomly divided into three dietary groups: control (CON), 0.4% FWBPs, and 0.1% SH, with six replicates of eight birds. The FWBPs and SH groups had a greater body weight (BW) at 21 and 42 d, average daily weight gain (ADG) in the starter period, average daily feed intake (ADFI) in the overall period, and feed-to-gain ratio (F:G) in the grower period. However, the ADFI was decreased by FWBPs supplementation and increased by SH supplementation in the grower period. The dry matter (DM) and organic matter (OM) digestibility were higher in the SH group at 21 d. At 21 d, the FWBPs group had an increased duodenal trypsin and serum glutathione peroxidase (GSH-Px) activity and immunoglobulin M (IgM) concentration, and a decreased liver malondialdehyde (MDA) concentration. The SH group had increased duodenal lipase activity, serum IgM, and interleukin-2 concentrations but decreased liver MDA concentrations. At 42 d, FWBPs and SH supplementation decreased duodenal trypsin and chymotrypsin and serum superoxide dismutase activity. Jejunum chymotrypsin activity and liver MDA content were decreased in the SH group. In conclusion, dietary FWBPs or SH supplementation during the starter period can improve growth performance and nutrient digestibility and enhance antioxidant capacity and immunity of broilers
The effect of different feeding strategies on honey bee gut microbiota and the presence of Nosema
No full textColony development in honey bees depends on both the environmental conditions and their genetic structure. Nutrition is the one of the most important factors in the honey bee’s health. This study was carried out in 48 colonies and included six groups (a control and five feeding groups). In the experiment, the effect of different feeding strategies on intestinal flora and the presence of Nosema was investigated. Pantoea agglomerans, Pseudomonas luteola, Burkholderia cepacia, Brevibacillus nitrificans, Sphingomonas paucimobilis, Aeromonas hydrophila, and P. alcalidimonas were detected in the intestinal microflora of the bee samples by morphological and phenotypic identification. The results of phenotypic identification were confirmed using 16S rRNA sequence analysis for P. agglomerans and B. nitrificans strains. The presence of Nosema was simultaneously investigated in all groups. Only Nosema cerenae was detected using DNA analysis in the positive Nosema spore samples
Influence of a Piriformospora indica plant-specific fungus and clove essence on broiler health and performance parameters during oxidative stress
No full textThe aim of this study was to evaluate the effects of dietary Piriformospora indica (PI) and clove essence (CE) and a combination of them (synbiotic) on performance and biochemical parameters after induction of stress using dexamethasone. The experiment was performed with 320 male, one-day-old chicks (Ross 308) using eight experimental groups and five replications. In each replication, eight chickens were fed a maize–soy-based diet. Experimental groups included group 1 (T1): control diet (based on maize and soybean without any feed additives); group 2 (T2): control diet with 0.2 cc dexamethasone injection; group 3 (T3): control diet with 11.6 cc CE; group 4 (T4): control diet with 10 mg PI; group 5 (T5): control diet with 11.6 cc of CE with 0.2 cc injection of dexamethasone; group 6 (T6): control diet with 10 mg PI and 0.2 cc of dexamethasone; group 7 (T7): control diet with synbiotic containing 10 mg of PI with 11.6 cc of CE; group 8 (T8): control diet with synbiotic containing 10 mg of PI and 11.6 cc of CE with 0.2 mg dexamethasone injection. PI and CE were poured into the drinking water during the rearing period. After 31, 33, 38, and 40 days, 2 mg/kg BW of dexamethasone was injected in the right breast muscle of experimental groups 2, 5, 6, and 8; after 35 and 42 days, samples were taken. The addition of CE, PI, and the synbiotic, caused an increase in body weight gain, feed intake, and reduced FCR compared to the control group in experimental groups 3, 4, and 7. The addition of 11.6 cc CE and 10 mg of PI caused an increase in body weight gain and feed intake and reduced FCR compared to the control group. Dexamethasone (0.2 mg) led to damage of the lymph organs, body weight loss, a reduction in humoral immunity, and side effects on performance parameters. Clove extract and the prebiotic reduced the adverse effects of dexamethasone.  
Prevalence of genitourinary infection in diabetic patients treated with SGLT 2 inhibitors
No full textIntroduction: Genitourinary infections are common in Diabetes patients compared to the general population more so in patients with Sodium glucose co transporter 2 inhibitors (SGLT2i) treatment , So, we did a study to find the prevalence of genitourinary infection in T2DM patients treated with SGLT2i.
Methods: One hundred and twenty patients receiving SGLT2i, who had signs and symptoms indicative of genitourinary infections were enrolled into the study.
Results: The mean age of presentation was 54.4 ± 7.7 years and percentage of males were 62 (51.66%). In this cohort, 72(60%) were treated with empagliflozin, 34(28.33%) with dapagliflozin and 14(11.66%) with canagliflozin. Twenty patients had genital mycotic infection and 4 had urinary tract infection. Female patients had higher incidence of infections than male patients with no statistically significant difference (P = ns). We did not find any significant correlation between age of the patient, gender, duration of disease and treatment, HbA1c, different types and dose of SGLT2i used with the incidence of genital mycotic infections(P = ns).
Conclusion: We need to counsel the patients before starting SGLT2i regarding possible chance of getting genitourinary infection, proper genital hygiene, drinking plenty of water and consulting the doctor if any symptoms at the earliest.
Keywords: Diabetes Complications; SGLT 2 inhibitors; genitourinary infections
A comprehensive review of the components of nurse-coordinated care which are most effective in preventing coronary heart diseases
No full textCoronary artery disease occurs when there is inadequate blood flow to the heart muscle as a consequence of coronary artery blockage, resulting in heart muscle failure. During normal heart action, cardiac muscles will always need an adequate supply of blood to fulfill their oxygen requirements. Coronary heart disease is the most common kind of cardiovascular disease in adults and the leading cause of mortality in the United States. Growing understanding of the possible significance of environmental and lifestyle variables in disease development has enhanced the job of the nurse coordinator, whether at a lower or higher levelof responsibility, to keep current ondiagnostic procedures, clinical symptoms, and innovative treatment choices. According to the national cardiovascular control program, secondary prevention of cardiovascular disease has increased, including measures such as cholesterol management, blood pressure monitoring, and smoking cessation. If you know more about NCC, it might be easier to figure out what roles it could play and what effects its use might have.
Keywords: Coronary Artery Disease (CAD); Nurse-Coordinated Care (NCC); Nursing Interventions (NI)
Analysis of the quality of the water and affectation on the health of the inhabitants of Guamachito, Colombia
No full textBackground: The study focuses on the evidence of the relationship between water quality and the health of populations. Colombia, a country with high levels of economic, social, and environmental vulnerability, does not have a population that has full access to drinking water. The study analyzes this relationship in Guamachito, Zona Bananera, Colombia.Objective: Analyze the water quality and the effect on the health of the population of Guamachito, Zona Bananera, Colombia.Method: Cross-sectional quantitative study, which was carried out in phases: First, an analysis of secondary data was carried out through a review of the web pages of the government institutions of public health in the region and the country; subsequently, a survey was applied to contrast the results of the documentary review to 450 inhabitants of Guamachito, Colombia, corresponding to members of a rural educational institution in the municipality, with 24 teachers and 426 students.Results: The results suggest that the microbiological characteristics are above the reference limits, as well as poor procedures for collecting and cleaning water in the houses, likewise, high rates of water-borne diseases are identified.Conclusion: It is inferred that there is an incidence of water quality on the health of the inhabitants of the Guamachito municipality
Obstetric ultrasound training programmes for midwives: A scoping review
No full textBackground: Antenatal care is essential for all expectant mothers and assists in reducing maternal mortality rates thus addressing the Sustainable Development Goal 3. Obstetric ultrasound complements antenatal care and is used in pregnancy to identify and monitor high-risk pregnancies. However, disparities exist and in low- and middle-income countries, ultrasound services are not readily available. This contributes to maternal and neonatal morbidity and mortality within these populations. Short ultrasound training programmes for midwives can be beneficial in alleviating some of the challenges experienced.
Aim: The aim of this scoping review was to identify global ultrasound education programmes for midwives.
Method: Articles containing suitable keywords were retrieved from databases suitable to nursing, education and ultrasound. Themes were developed based on the articles included in the review.
Results: A total of 238 articles were identified, and after the duplicates and irrelevant studies were removed, 22 articles were included. Articles were analysed and discussed under the identified themes and categories.
Conclusion: It is essential that sufficient training is provided to medical professionals performing obstetric ultrasound so that adequate and safe care is offered to expectant mothers. With the introduction of ultrasound in low- resource settings, the knowledge of safety and competencies required to operate the equipment necessitate adequate training. Developed programmes have been found to meet the demands of the ever-changing workforce and allow for midwives to perform focused obstetric ultrasound examinations.
Contribution: This scoping review highlighted ultrasound training programmes for midwives and provided guidance on the development of future midwifery ultrasound training programmes. 
Disease severity and renal function among sickle cell anaemia patients in a tertiary hospital, South-south, Nigeria: a cross sectional study
No full textBackgroundRenal disease is a recognized complication of sickle cell anaemia (SCA), especially from the third decade of life and is linked to disease severity. This study assessed the association between disease severity and renal function among SCA patients using routine and newer markers of renal function.MethodsThis cross-sectional study recruited 85 SCA patients. Disease severity was assessed using modified Adegoke criteria which include the frequency of transfusion, painful crises, packed cell volume, and history of complications such as hypertension and chronic leg ulcers. Renal function was assessed using urea, creatinine, and beta-2-microglobulin (β2-M). Association was determined between renal function and disease severity using Pearson’s correlation. P-value < 0.05 was taken as significant. ResultsThe mean age of participants was 27.2 ± 7.6 years with 41(48.2%) males and 44 (51.8%) females. The mean packed cell volume, serum creatinine, serum urea, and β2-M were 24.0± 4.1%,17.6±7.5 mg/dL, 0.7±0.3mg/dL, 3.4±1.2mg/l respectively. A majority (54.1%) of them had a mild disease while 35.3% and 10.6% had moderate and severe diseases, respectively. Forty of the SCA patients had urine specific gravity below 1.010. The mean values of systolic blood pressure (p=0.001) diastolic blood pressure (p=0.001), serum creatinine (p=0.028) and β2M (p=0.019) significantly increased with disease severity. There was a significant positive correlation between SCA disease severity and serum urea (r=0.229; p=0.035), and serum β2-microglobulin (r=0.270; p=0.012).Conclusion Sickle cell anaemia severity is associated with a decline in renal function using both traditional and novel renal markers. Serum β2-M may serve as a useful marker of renal function and disease severity in SC
Epidemiology of out-of-hospital cardiac arrest: comparison of Turkish nationals and refugees
No full textThe aim of this study is to conduct an epidemiological examination of Turkish citizens and refugees who requested an ambulance due to Out-of-hospital cardiac arrest (OHCA) at the Kayseri 112 emergency services between 2019 and 2020. This study was carried out in the province of Kayseri, which is one of the largest cities in Turkey. The study population includes OHCA patients for whom EMS were activated for any reason in 2019-2020. Data were taken from the Emergency Healthcare Automation System used by Kayseri Emergency Medical Services. A total of 5977 OHCA cases (Turkish 5736, Refugees 241) in which Emergency Medical Servises (EMS) was activated during the research period were included. A rate of 55.6% of patients Turkish nationality and 66.0% refugees were male (p<0.001). Observing at the cause of arrest, we find that 95.7% of cases among Turkish citizens and 82.6% of cases among refugees had a medical cause; while the suicide rate among Turkish citizens was 0.9%, this rate was 5.0% in refugee patients (p<0.001). It was found that the rate of OHCA increased with age and that the average OHCA age was lower in men and refugees. In addition, there is no difference between Turkish nationals and refugees in the use of emergency services for OHCA case
No sign of Rotavirus co-infection in COVID-19 patients with gastrointestinal symptoms
No full textBackground and aimsThe main goal of the present study is to investigate the incidence of Rotavirus co-infection in COVID-19 patients.Methods and Results Fecal samples of COVID-19 patients with gastrointestinal symptoms which had positive PCR- were collected from Abadan’s hospital, Iran during the period December 2020 to January 2021. Samples were analyzed by RT-PCR to determine the presence of Rotavirus. Finally, the total samples size of 37 were included in this study. The mean age of patients was 48.22 years. Abdominal pain alone was detected in 48.65% of the patients. At least one gastrointestinal symptom was detected in all of the patients. Diarrhea and fever were seen in 13.51% and 59.46% of patients, respectively. Nausea and vomiting were seen in 5.41% of the patients. RT-PCR showed no infection of Rotavirus among the patients. ConclusionGastrointestinal symptoms related to COVID-19 are common. More studies is need among these patients groups for investigate co-infection with other fecal viral shedding carries, due to a worse prognosis and its association with disease severity