Lynn University
Lynn University: SPIRAL (Scholarly Publications, Institutional Repository and Archives at Lynn)Not a member yet
14847 research outputs found
Sort by
2025 Commencement
A 2025 Lynn University graduate and their loved ones pose for photographs at the Palm Beach Convention Center.https://spiral.lynn.edu/commencement-photos-2025/1025/thumbnail.jp
2025 Commencement
A 2025 Lynn University graduate stands with their loved ones at the Palm Beach Convention Center.https://spiral.lynn.edu/commencement-photos-2025/1040/thumbnail.jp
2025 Commencement
2025 Lynn University graduates take a selfie.https://spiral.lynn.edu/commencement-photos-2025/1090/thumbnail.jp
2025 Commencement
A 2025 Lynn University graduate poses for a photograph at the Palm Beach Convention Center.https://spiral.lynn.edu/commencement-photos-2025/1099/thumbnail.jp
2025 Commencement
2025 Lynn University graduates pose for photographs at the Palm Beach Convention Center.https://spiral.lynn.edu/commencement-photos-2025/1100/thumbnail.jp
2025-2026 Welcome Convocation
Welcome Convocation for incoming students and faculty kicks off academic year 2025-2026.
Date and Time: Sunday, Aug. 17, 2025, 5 p.m. EDT
Location: The Count and Countess de Hoernle Sports and Cultural Center
Faculty Speaker: Professor Joseph Ingles, Assistant Professor, Program Coordinator for Data Analytics, College of Business and Managementhttps://spiral.lynn.edu/welcome-convocation-videos/1005/thumbnail.jp
The Role of the JNK Gene in Ovarian Cancer Inflammatory Pathways
Ovarian cancer, one of the leading causes of cancer-related deaths in women globally, presents a significant challenge due to its common late-stage diagnosis and chemoresistance (inability of the tumor to respond to drugs). The c-Jun N-terminal kinase (JNK) signaling pathway plays a crucial role in ovarian cancer progression, contributing to inflammation, tumor survival, metastasis, and chemotherapy resistance. This literature review examines the role of the JNK signaling pathway in ovarian cancer, with a focus on its role in inflammation, metastasis, and chemoresistance. JNK regulates key inflammatory cytokines, such as TNF-α and IL-6, which promote tumor growth and immune evasion. Moreover, it influences cellular processes including migration, invasion, and epithelial-to-mesenchymal transition (EMT), which are crucial for metastasis. JNK promotes chemoresistance by activating survival pathways that allow tumor cells to withstand chemotherapy-induced apoptosis. While JNK inhibitors show promise as a therapeutic strategy, several challenges remain, including selectivity, toxicity, and the development of resistance mechanisms. In vivo studies using patient-derived models are necessary to better understand JNK’s role in ovarian cancer and to refine therapeutic approaches. Additionally, personalized medicine strategies that identify specific molecular markers predicting response to JNK inhibition are crucial for optimizing treatment. Combining JNK inhibitors with chemotherapy or immune checkpoint blockage may be synergistic. Such combinations could improve outcomes and help overcome current therapeutic barriers
The Role of Nicotine in Treating Neurodegenerative Diseases
Neurodegenerative diseases have emerged as a critical medical challenge because they cause progressive neuronal death alongside structural or functional deterioration. Families, healthcare institutions, and affected individuals face significant challenges due to neurodegenerative diseases such as Alzheimer\u27s, Parkinson\u27s, and Huntington\u27s diseases, which impair both cognitive function and motor abilities. Researchers have found that nicotine in tobacco products is a compound with therapeutic potential. This literature review explores how nicotine interacts with neurodegenerative mechanisms, such as oxidative stress and inflammation, and assesses its potential neuroprotective effects in conditions like Alzheimer\u27s and Parkinson\u27s diseases. In the central nervous system, nicotine binds to the nicotinic acetylcholine receptor, modulating neurological processes such as memory formation and learning. Recent research suggests that nicotine may exert neuroprotective effects by activating these receptors, potentially reducing the progression or severity of neurodegenerative diseases. This review uses previous research and clinical trials to explain these effects mechanistically, while showing their practical value for healthcare. It will illustrate essential concepts about neurodegenerative diseases as well as nicotine\u27s pharmacological features. The paper reviews scientific findings about nicotine\u27s activity in neural signaling pathways, evaluates its potential for therapeutic and clinical use, and discusses social and ethical implications. Furthermore, this paper reviews investigates nicotine’s dual nature by exploring its potential to protect neural function in the context of neurodegenerative diseases, while also addressing the significant risks posed by its addictive properties and adverse effects on long-term brain health
Saliva & Circadian Rhythm in Medical Profiling for Early Disease Prevention
Circadian rhythms affect almost every biological process from hormone secretion, gene expression, immune regulation, and metabolism. Studies show that disruption to these internal rhythms through irregular sleep, artificial sleep, and irregular sleep can significantly increase risk for chronic disease such as diabetes, cardiovascular disorders, neurodegeneration, and cancer. Saliva presents a viable alternative for capturing biomarkers found through blood or cerebrospinal fluid, offering substantial utility for diagnostic and chronobiological profiling. Saliva contains hormones such as cortisol and melatonin while containing inflammatory markers that fluctuate rhythmically throughout the day. Due to its ease of collection, saliva is well suited for longitudinal monitoring, screening in most populations, and can be integrated into health platforms. Findings suggest salivary biomarkers can offer insight into when a dysfunction occurs. This time sensitivity allows clinicians to detect early biological changes before symptoms manifest. Saliva sampling removes logistical and ethical concerns associated with more invasive methods, making it ideal for repeated use in most community settings. Aligning diagnostic practices with circadian principles advances preventative care and creates a personalized model of medicine. This literature review examines the potential of salivary diagnostics with circadian biology to create time sensitive, patient friendly tools for disease prevention
Infrared Spectroscopic Study of Hydrogen Bonding Associations Through C-O Band Intensities in Isopropanol-Water and t-Butanol-Water Mixtures
We investigated the hydrogen bonding in isopropanol-water and t-butanol-water mixtures in the mole fraction range 0.1 to 0.9 through the application of infrared spectroscopic technique. The inherent high intensity of the C-O band helps detect small changes in the hydrogen bonding associations. The integrated areas of the C-O stretching band versus mole fractions were plotted for both mixtures. The C-O plot areas were used to explain the molecular associations in the mixtures studied