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    Psychosocial factors and patient experience associated with diabetes treatment discontinuation : a cross-sectional study in Japan

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    Objectives, The prevention of treatment discontinuation is crucial in mitigating the adverse consequences of diabetes. This study aimed to identify the psychosocial factors and patient experiences associated with the discontinuation of diabetes treatment. Design, A cross-sectional study was conducted. Setting, A nationwide online survey with convenience sampling. Participants, Participants, aged 40–79 years, who reported living with diabetes, were included. Primary and secondary outcome measures, Treatment continuation status was the outcome variable. Participants who previously received regular treatment but were not currently under medical care were classified as the treatment discontinuation group. Psychological factors (mood and anxiety disorders, self-esteem, procrastination), social factors (loneliness, economic difficulties, adverse childhood experiences) and patient experiences and opinions regarding diabetes were assessed. Results, A total of 4715 individuals were included in the analysis. After adjusting for confounders, psychological distress (adjusted OR (AOR)=1.87, 95%CI (1.06 to 3.30), p=0.032) and higher procrastination (AOR=2.64, 95%CI (1.25 to 5.56), p=0.011) were significantly associated with treatment discontinuation. Overall, 9.7% of participants reported financial hardship, and 12.1% reported diabetes burnout during their course of treatment. Financial hardships (p=0.002), difficulty with child or older adult care (p<0.001) and diabetes burnout (p=0.001) were significantly more common in the treatment discontinuation group than in the continuation group.Conclusions, Psychological distress and higher procrastination levels were significantly associated with diabetes treatment discontinuation, after adjusting for potential confounders. The treatment discontinuation group reported significantly more psychosocial challenges than the continuation group. Healthcare providers and systems should prioritise addressing the psychosocial characteristics, experiences and challenges faced by individuals with diabetes

    A Report of Teacher Training Consultation

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    チイキ キョウイク ガク ケンキュウ : オクヅケ

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    Association of Resilience with Psychological Distress, Burnout, and Depression Among Direct Support Professionals : A Cross-Sectional Study During the COVID-19 Pandemic

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    Background, COVID-19 pandemic-related changes have increased mental health problems of essential workers. However, little is known about its impact on direct support professionals (DSPs) working at facilities for people with disabilities. This study examined the resilience and related factors, including psychological distress, burnout, depression, among DSPs working during the COVID-19 pandemic, including those in facility with cluster occurrences in Japan. Methods, We conducted an online survey from May 18 to June 9, 2021, targeting staff at Social Welfare Corporation Shirane Gakuen, a cluster facility. An additional survey was conducted on May 24, 2021, through Yahoo! Crowd Sourcing, targeting individuals who worked at disability support facilities categorized as non-cluster facilities. We obtained 108 and 95 responses, respectively, including 76 and 16 DSPs. The following instruments were used: Maslach Burnout Inventory-General Survey, Bidimensional Resilience Scale, Kessler 6-item Psychological Distress Scale, and Patient Health Questionnaire-9. Multiple regression analysis was conducted to examine associations between resilience and related factors. Results, The prevalence of severe psychological distress, burnout, and depression among DSPs within the COVID-19 cluster facility was 11.8%, 69.7%, and 29.0%, respectively. In the non-cluster facilities, the prevalence was 37.5%, 68.8%, and 62.5%, respectively. A positive association between acquired resilience factors and burnout was observed (coefficient = 2.35, 95% CI 0.38 to 4.31). However, no significant association was observed between acquired resilience factors and the interaction term of COVID-19 cluster occurrences at the workplace and burnout (coefficient = –2.03, 95% CI –6.97 to 2.90). Conclusion, This study demonstrated that the acquired resilience factors of Japanese DSPs was linked with increased burnout during the COVID-19 pandemic, regardless of the COVID-19 cluster occurrences. As burnout intensifies, DSPs may cultivate acquired resilience, and programs enhancing these factors may help alleviate their burnout and promote well-being

    Characteristic Symptoms and Associated Risk Factors of COVID-19 Reinfection in the Indonesian Community

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    Background, The Coronavirus disease 2019 1 global pandemic is transmitted through respiratory droplets from infected people. We aim to determine the risk factors for COVID-19 reinfection, and the degree of its severity in patients reinfected with it. Methods, We conducted a cross-sectional study on COVID-19 reinfection in Semarang, Indonesia using the two-stage sampling technique. There were a total of 312 participants. We used logistic regression tests for multivariate analysis of reinfection risk associated with various factors. The study spanned from June 2022 to October 2022. Results, We found that symptoms such as cough and sore throat, seen during first infection, often recurred during reinfection. The fixed multivariate result showed that males (OR 3.863; 95% CI 1.459-10.234; P = 0.007), persons having comorbidities (OR 2.382; 95% CI 1.025-5.536; P = 0.044), health workers (OR 32.881; 95% CI 3.120–346.566; P = 0.004) or non-health workers (OR 21.661; 95% CI 2.192–214.034; P = 0.008), persons with mild symptoms (OR 6.503; 95% CI 2.771–15.264; P< 0.001) or moderate symptoms (OR 43.408; 95% CI 5.963–315.980; P < 0.001) at first COVID-19 infection, persons displaying poor rule-following behavior (OR 4.162; 95% CI 1.569–11.037; P = 0.004) and having only a middle school education (OR 0.303; 95% CI 0.098-0.93; P = 0.037) were highly related parameters associated with COVID-19 reinfection. Conclusion, Thus, we found that males having comorbidities, employed in public jobs (health and non-health workers), with mild or moderate severity during first infection, and displaying poor rule-following behavior hold the highest risk factors for COVID-19 reinfection. Interestingly, having at least a middle school education seems to be a protective factor against COVID-19 reinfection

    Localized Nodular Amyloidosis of the Buccal Mucosa Associated with Sjögren’s Syndrome : A Case Report and Literature Review

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    Amyloidosis is a group of disorders in which specific precursor proteins form insoluble amyloid fibrils are deposited in various organs and extracellular spaces. Sjögren’s syndrome (SS) is a chronic inflammatory disease in which lymphocytes infiltrate the exocrine glands, such as the salivary and lacrimal glands, through an autoimmune mechanism. At advanced stages of SS, localized nodular amyloidosis has been reported in specific organs outside the glands. Herein, we report a case of localized nodular amyloidosis associated with SS. An 80-year-old woman, who had been biting her buccal mucosa for several years and was aware of the presence of a mass, which had increased in size since approximately 6 months, was referred to our hospital. The patient had a history of SS and systemic lupus erythematosus since her 50s. A needle biopsy was performed because malignancy was suspected by magnetic resonance imaging. The pathological diagnosis was ATTR-type amyloidosis. The patient underwent excision of the lesion to improve the swelling. The pathological findings showed plasma cell infiltration in some areas, which required differentiation from AL amyloidosis; therefore, the patient was referred to a facility specializing in amyloidosis. The pathological diagnosis was AL amyloidosis. Various clinical findings ruled out systemic involvement and the final pathological diagnosis was localized nodular amyloidosis. It has been reported that it may occur in the advanced stages of SS, and our patient had SS for 30 years. One year after the surgery, the patient’s prognosis was good

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