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    Predictors of Renal Replacement Therapy Requirement in Acute Kidney Injury Due to Urinary Sepsis: A Single-Center Retrospective Study

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    Background, Urosepsis is defined as sepsis caused by an infection of the urogenital tract and is a systemic response to infection. Urosepsis is commonly treated in the intensive care unit (ICU) because of its acute and potentially lethal nature. Acute kidney injury (AKI) is a common complication of septic shock in ICU patients. This study predicted cases in which patients required renal replacement therapy (RRT) during the early stages of hospitalization. We also examined the relationship between the clinical information obtained at admission and the subsequent need for RRT. Methods, This single-center, retrospective, observational study included 114 patients with sepsis caused by tract infections. We examined the multiple factors associated with AKI using clinical and social information. AKI was defined according to the Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guidelines, with severe AKI defined as AKI requiring RRT. Logistic regression analyses were performed to identify the significant factors associated with severe AKI based on the information obtained at the time of admission. Results, Severe AKI occurred in 12 patients. Multivariate analysis revealed that two factors were significantly associated with severe AKI: a high leukocyte count in the peripheral blood (> 22,100/μL) at admission (odds ratio: 21.972, 95% CI: 1.798–268.481) and the administration of vasopressors (odds ratio: 13.327, 95% CI: 1.009–176.091). Conclusion, Physicians should be vigilant of the potential development of severe AKI in cases of urosepsis, particularly when patients require vasopressor and present with extremely high peripheral blood leukocyte counts at admission

    Prevalence and dual use of cigarettes, heated tobacco products and electronic cigarettes among young adults in Japan : findings from a 2019 Nationwide Survey

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    Objectives, This study aims to estimate the prevalence and dual use of cigarettes, heated tobacco products (HTPs) and electronic cigarettes (e-cigarettes) among individuals aged 18–24 in Japan. Design, This cross-sectional study involved a door-to-door survey administered by trained interviewers using a structured questionnaire. Setting, Individuals aged 18–24 residing in 220 areas within 10 ordinance-designated cities (Sapporo, Sendai, Saitama, Chiba, Yokohama, Kawasaki, Sagamihara, Nagoya, Osaka and Fukuoka) as well as Tokyo’s 23 wards in Japan in 2019 were included. Participants, A total of 1738/5500 individuals were included in the analysis, with participants evenly distributed by sex, age and residential area. Primary and secondary outcome measures, Cigarette, HTP and e-cigarette use was assessed. Results, The weighted prevalence of the current use of cigarettes, HTPs and e-cigarettes accounted for 10.1% (95% CI 8.7, 11.5), 5.1% (95% CI 4.1, 6.1) and 1.8% (95% CI 1.2, 2.4), respectively. Approximately 68.2% of the people who used HTPs at the time were dual users of both HTPs and cigarettes. There was a significant gap in tobacco product use between individuals aged 20–24 and those aged 18–19, with this difference remaining after adjusting for covariates. Conclusions, In 2019, cigarettes were the most used tobacco-related product among young adults in Japan. Smoking initiation appears to notably increase at age 20 when smoking becomes legal in Japan. The prevalence of HTP use among young adults in Japan is notably higher than in other countries

    ホウコク イチ : チイキ ガクブ ニ オケル ガクシュウ シエン ノ ゲンジョウ ト カダイ

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    ホウコク サン : コウガクブ ニオケル ガクシュウ シエン

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    レイワ ロクネンド ゼンガク キョウツウ カモク ジュギョウ アンケート シュウケイ

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    Study on Cyclic Stress Measurement Method using Electrodeposited Metal Foil(Principal Stress Measurement using XRD method)

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    鳥取大学Tottori University博士(工学

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