Archivio Istituzionale della Ricerca- Università degli Studi di Foggia
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    Diagnosis and treatment of cardiac amyloidosis in Italy: Results of the survey of the Italian Cardiac Amyloidosis Network (RIAC)

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    Background. The national survey of the SIC-ANMCO Amyloidosis Centers was designed to create a geographical mapping of the centers that identify and follow patients with cardiac amyloidosis in Italy and to describe their diagnostic capabilities and multidisciplinary organization. Methods. The survey was administered to 212 centers in Italy. Among them, 153 centers responded (72%), 31/35 (89%) of which were academic medical centers and 122/177 (69%) hospitals. Results. The results revealed a prevalence of centers in the North and Center of Italy compared to the South and the Islands, highlighting a greater number of patients in heart failure/cardiomyopathy clinics in hospitals (53%) and in clinics dedicated to amyloidosis in academic medical centers (71%). Most centers have an internal multidisciplinary collaboration network with the neurologist (82% in total, 97% in academic medical centers and 78% in hospitals) and the hematologist (69% in total, in 94% and 63%, respectively) and have the possibility of performing on-site cardiac magnetic resonance imaging (74%, in 94% and 68%, respectively) and scintigraphy with bone tracers (52%, in 91% and 44%, respectively), or alternatively to refer patients to other centers thanks to well-structured or occasional collaborations. Conversely, only a minority of centers perform endomyocardial biopsy (31%, in 71% of academic medical centers and in 20% of hospitals) and a smaller number of academic medical centers perform sophisticated amyloid tissue typing techniques such as immunogold labeling (11%) and mass spectrometry (4%). Conclusions. The survey provided important information on the current Italian situation, underlining the importance of collaboration between the various levels of the network, to guarantee the best possible pathways and treatments for all patients with amyloidosis

    Sostenibilità e circolarità a garanzia di un’eredità per i posteri. Ciò che è e ciò che può essere

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    Sostenibilità e circolarità a garanzia di un’eredità per i posteri, Ciò che è e ciò che può essere è lavoro nasce dalla necessità di fornire un metodo utile, concreto ed innovativo per la valutazione del raggiungimento degli obiettivi dell’Agenda 2030. Gli studi condotti sino ad ora si limitano a “decantare” l’operato delle Amministrazioni Comunali ma la presente ricerca offre un quid pluris che ci si auspica possa risultare utile nell’ambito della valutazione del raggiungimento degli SDGs da parte degli Enti Locali, in particolar modo dei Comuni, gli Enti, per antonomasia, più vicini al cittadino. La natura dell’ente “Comune” presuppone l’elemento vincente del lavoro, ovverosia, una valutazione dal basso (bottom-up) che ci riporta all’essenza dell’Agenda21. Il risultato è un Framework Operativo ribattezzato “Agenda 21+2030” che, con il supporto degli strumenti tecnologici attualmente esistenti quali AI e IoT, consente un rapporto diretto fra gli obiettivi dell’Agenda 2030 e i soggetti protagonisti e strumentali al raggiungimento degli stessi ovvero i cittadini, stakeholder, Pubbliche Amministrazioni ed enti del Terzo Settore. Dopo un’attenta ricostruzione storico-didattica dei concetti di “sostenibilità” e “circolarità” articolata nei primi due capitoli, le vedute oltre l’orizzonte del presente vengono ampliate nel terzo capitolo. L’ultima sezione del lavoro è dedicata al “tema caldo” della ricerca: prendendo come caso di studio la municipalità di Cerignola e l’impegno profuso nel perseguimento dei SDGs si giunge alla costruzione di un metodo concreto ed efficace, un valido strumento di misurazione per l’analisi e il raggiungimento degli obiettivi dell’Agenda 2030 attraverso i fondamenti dell’Agenda 21

    Messi all'Indice. Carnelutti recensore

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    EduGreen e Aule Natura: la pedagogia del benessere sostenibile.

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    Energy Requirements in the Post-ICU Period: An Exploratory Multicenter Observational Study

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    Background: There is limited knowledge about nutritional intake and energy needs during the post-intensive care unit (ICU) period and their relationship with clinical outcomes and physical recovery. Aims and Methods: Thus, this observational multicenter study (Azienda Ospedaliero-Universitaria “Santa Maria”, Terni and “Madonna del Soccorso” General hospital, San Benedetto del Tronto, Italy) aimed, firstly, to measure energy expenditure via indirect calorimetry (IC) (Q-NRG+® Metabolic Monitor, Cosmed, Rome, Italy), derived respiratory quotient (R/Q1) and, malnutrition risk via Mini Nutritional Assessment (MNA) test and body composition through bioimpedance vector analysis (BIVA-Akern, Pontassieve, Italy); secondly, to assess their effect on energy needs, body composition and physical rehabilitation steps in critically ill adults after ICU discharge. The provision of nutrients (PIS test) was also recorded. Oral nutritional supplementation was used to reach the optimal nutritional intake. All patients followed a standardized rehabilitation program. Results: A total of 43 patients were enrolled from January 2024 until February 2025 at the beginning of their post-ICU period. The mean age was 65.7 ± 1.0 years, the mean BMI was 20.73 ± 0.8 kg/m2 at the recovery ward, and 60.4% (n = 26) were male. The mean admission period was 19.5 ± 1.7 days. The resting energy expenditure (mREE) was 1591 ± 71.2 at the admission and 1.856 ± 62.7 kcal/kg/d at the discharge (p < 0.05). The median phase angle value was 4.33 ± 0.15 at the admission and 5.05 ± 0.17° at the discharge (p < 0.05); R/Q1 at the admission was 0.7 ± 0.1 and 1.086± 0.11 at the discharge (p < 0.05). Improved energy expenditure significantly correlated with R/Q1 and phase angle (r = 0.81 and r = 0.72, respectively). Interestingly, there was no significant correlation between improved metabolism and improved PIS test scores (r = 0.18). Improved metabolism and nutritional status showed a tendency to correlate with shorter post-ICU courses and earlier physical recovery, without reaching statistical significance. Conclusions: Measurement of energy expenditure and caloric intake, along with the assessment of body composition is feasible and provides an objective tool to guide and possibly enhance the functional recovery in patients during the post-ICU period

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