Brage Nord Open Research Archive
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Oppbyggingen av sangfag ved skuespillerutdanningen ved Nord universitet i perioden 2012 til 2017
Full text linkComparative transcriptome analysis reveals a serotype-specific immune response in Nile tilapia (Oreochromis niloticus) infected with Streptococcus agalactiae
Full text linkStreptococcus agalactiae is a major causative agent of streptococcosis in Nile tilapia (Oreochromis niloticus) and understanding its etiology is important to ensure the sustainable development of global tilapia farming. Our research group recently observed contrasting disease patterns in animals infected with two different S. agalactiae serotypes (Ib and III). To better understand the basis for these divergent responses, we analyzed the brain transcriptome of Nile tilapia following bacterial exposure. Our findings revealed significant variation in the expression of genes involved in immune (e.g., CD209 antigen, granulin, C-X-C motif chemokine 10, prostacyclin synthase, and interleukins) and neuroendocrine (e.g., mmp13a, mmp9, brain aromatase, and pmch) pathways. The serotype Ib strain seems promptly recognized by the host, triggering a potent inflammatory response, whereas the serotype III strain elicited a less immediate response, resulting in more pronounced central nervous system (CNS) symptoms and behavioral effects. To the best of our knowledge, this is the first study to show serotype-specific immune responses to S. agalactiae in Nile tilapia. These findings are important for advancing disease management and control strategies in aquaculture. Identifying different immune reactions triggered by serotypes Ib and III may assist the development of more specific approaches for preventive measures, early detection, and effective treatment against streptococcosis.publishedVersio
Allelopathic effects of leaf powder from selected agroforestry tree species on the germination, growth, and yield of staple crops in a semiarid region
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Is it Possible to View a Trading System for CO<inf>2</inf> Certificates from Agricultural Soil as a Genuine Regenerative Circular Economic Business Model?
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Interdisciplinary strategies for establishing a trusting relation as a pre-requisite for existential conversations in palliative care: a grounded theory study
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Nursing students' motivation for, and experiences from, participating in a blended intensive programme on mass casualty incidents: a qualitative study
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Prevalence and density of Elaphostrongylus rangiferi larvae in faecal samples of semi-domestic reindeer (Rangifer tarandus tarandus) in Norway 2013-16
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Association between anti- Mullerian hormone levels and age in women with endometriosis: insights from a population-basedstudy
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