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Post-diagnosis physical activity and sedentary behaviour and colorectal cancer prognosis: A Global Cancer Update Programme (CUP Global) systematic literature review and meta-analysis
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Risk assessment of Psychrobacter sp. as plant protection product - Nemaslug
Get PDFHelse- og miljørisiko ved bruk av bakterien Psychrobacter sp. i plantevernmiddelet Nemaslug® Helserisikoen for mennesker ved bruk av Nemaslug® anses som lav, men man kan ikke utelukke risiko for svært infeksjonsutsatte pasientgrupper. Det er ingen bevis for helseproblemer som oppstår ved inntak av matvarer behandlet med Nemaslug®. Vitenskapskomiteen for mat og miljø (VKM) har, på oppdrag fra Mattilsynet, utført en risikovurdering av bakterien Psychrobacter sp. som inngår i plantevernmiddelet Nemaslug®. Plantevernmiddelet Nemaslug®, som er godkjent for bruk i Norge siden 2005, inneholder nematoden Phasmarhabditis hermaphrodita. Nematoden bærer en symbiotisk bakterie som fungerer som den aktive biokontrollorganismen ved å produsere giftstoffer som dreper snegler ved infeksjon. Bakgrunnen for oppdraget er at det ble avdekket at bakterien i Nemaslug® ikke er Moraxella osloensis, som den tidligere godkjenningen er basert på. Den er i stedet blitt identifisert som en art i bakterieslekten Psychrobacter, mest sannsynlig Psychrobacter faecalis, alternativt Psychrobacter pulmonis. Denne vurderingen skal danne grunnlag for Mattilsynets beslutning om hvorvidt Nemaslug® skal beholde sin godkjenning for bruk i Norge eller ei. Resultater Det er begrenset informasjon om helsefarene ved Psychrobacter sp. hos mennesker. Kunnskap om antibiotikaresistens og patogenisitet i slekten Psychrobacter er i stor grad mangelfull. Det er lite informasjon om forekomsten av Psychrobacter sp. i Norge. Potensialet for spredning og etablering av Psychrobacter sp. i miljøet under norske forhold vurderes som lavt. Risikoen Nemaslug® utgjør for ikke-målorganismer, spesielt bløtdyr, er usikker og krever videre forskning. Videre taksonomisk analyse og fullstendig genomsekvensering er nødvendig for å bekrefte artstilhørigheten til bakterien i Nemaslug®. Konklusjoner Selv om informasjonen om helsefarene knyttet til Psychrobacter sp. hos mennesker er begrenset, betraktes den generelt som et lavrisikopatogen. Helserisikoen for mennesker ved bruk av Nemaslug® anses derfor som lav, men risiko for pasientgrupper som er svært mottakelige for infeksjoner kan ikke utelukkes. Det er ingen bevis for helseproblemer som oppstår ved inntak av matvarer behandlet med Nemaslug®. Metode VKM har hentet data og informasjon fra søkeren via Mattilsynet og VKMs forrige rapport om Nemaslug®. Et grundig litteratursøk ble gjennomført for å innhente ytterligere relevant informasjon. Vurderingen er godkjent av VKMs faggruppe for plantehelse.Risk assessment of Psychrobacter sp. as plant protection product - NemaslugpublishedVersionsubmittedVersionpublishedVersio
Green spaces and respiratory, cardiometabolic, and neurodevelopmental outcomes: An individual-participant data meta-analysis of >35.000 European children
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Effective and simple interventions to improve outcomes for preterm infants worldwide: The FIGO PremPrep-5 initiative
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Assessing alcohol consumption across phosphatidylethanol levels using HDL-cholesterol as a predictor
Get PDFAims: Prior research has established a correlation between increases of High-Density Lipoprotein Cholesterol (HDL-C) levels and alcohol consumption. This study aimed to explore the association between phosphatidylethanol (PEth) levels and the amount of consumed ethanol, utilizing HDL-C as a surrogate marker on a population level. This endeavor offers an adjunct to other studies. Methods: PEth and HDL-C levels in 50 751 samples from 29 899 patients in Norway were measured simultaneously in whole blood and serum, respectively. Linear mixed model analyses were employed to assess HDL-C levels within different PEth intervals. Drawing on previous research indicating an increase of .0035 mmol/L in HDL-C per gram of pure ethanol consumed per day, and assuming no alcohol intake in the zero PEth group, we estimated mean daily ethanol intake at the group level for males in each PEth interval. Results: Results revealed a significant correlation between PEth and HDL-C levels (Spearman’s rho = .385 for women, .420 for men, PAssessing alcohol consumption across phosphatidylethanol levels using HDL-cholesterol as a predictorpublishedVersio
Exploring dual diagnosis in opioid agonist treatment patients: a registry-linkage study in Czechia and Norway
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Immediate or delayed trial without catheter in acute urinary retention in males: A systematic review
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Digital self-presentation and adolescent mental health: Cross-sectional and longitudinal insights from the “LifeOnSoMe”-study
Get PDFBackground The intensive use of social media among adolescents has caused concern about its impact on their mental health, but studies show that social media use is linked to both better and worse mental health. These seemingly contradictory findings may result from the diverse motivations, interactions, and experiences related to social media use, and studies investigating specific facets of social media use in relation to mental health and well-being, beyond general usage metrics, have been called for. Aspects of self-presentation on social media, such as feedback-seeking and upwards social comparison have been linked to worse mental health, however, there is a need for more studies exploring the relationship between self-presentation on social media and adolescent mental health over time. Aim The aim of this study was to explore the cross-sectional and longitudinal relationship between aspects of self-presentation and depression, anxiety, and well-being among adolescents. Methods This study utilised both cross-sectional and longitudinal datasets from the LifeOnSoMe-study, comprising 3,424 and 439 participants, respectively (OSF preregistration https://doi.org/10.17605/OSF.IO/BVPS8). Latent Class Analysis (LCA) was used to identify similar response patterns within the Self-Presentation and Upwards Social Comparison Inclination Scale (SPAUSCIS). Regression models and first differencing methods were applied to evaluate the cross-sectional and longitudinal associations between focus on self-presentation and mental health and well-being among adolescents. Results A strong emphasis on self-presentation was linked to increased levels of depression and anxiety in both males and females, and reduced well-being in females when compared to those with lower or intermediate self-presentation focus. The effect sizes ranged from small to medium. Furthermore, an escalation in self-presentation focus over time was associated with a slight increase in symptoms of anxiety and depression; however, the association with well-being did not reach statistical significance. Conclusion The results of the present study suggest that a heightened focus on self-presentation, which includes behaviours such as seeking feedback, employing strategic self-presentation tactics, and engaging in upward social comparisons, is associated with an elevated risk of reduced mental health.publishedVersio
