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    [[alternative]]A Study on the Business Model of Regional Dance Troupe

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    [[abstract]]本研究以商業模式切入表演藝術領域舞團之經營概況,從此方向做深入探討。臺灣表演藝術一直以來未能稱上產業,但根據每年臺灣文化創意產業年報所述,表演藝術團體(包含音樂類、舞蹈類、現代戲劇類、傳統戲劇類)歷年活動數不勝數,被認定為非營利組織的表演團體更是自負盈虧,且又隨著大環境的變化,如近幾年疫情的肆虐,導致表演團體改變經營模式,然而還是有堅持追求表演藝術的工作者們努力著,從逆境中取得經驗,帶著團隊持續走下去。商業模式看似與表演藝術毫無關聯,但若能藉由商業模式的邏輯思維來看待表演藝術團體的經營,是否更能達到優良的永續經營績效?本研究以商業模式理論為核心,從商業模式畫布圖延伸建構「表演藝術商業模畫布式檢視表」為研究工具,嘗試導入表演藝術領域舞團檢視其經營概況,以立意抽樣選擇中部地區舞團,包括臺中極至體能舞蹈團及南投薪傳舞蹈團,更與成功的表演團體如雲門舞集和朱宗慶打擊樂團進行個案分析比較,以多重研究行為蒐集文獻,藉此研究工具深入探討團隊商業模式,提供地區性舞團在未來經營方針的參考。研究發現,使用商業模式畫布來看待表演藝術團體,不管是地區性團隊或是經營穩定團隊,皆能透過九個構面中清楚發現其問題何在。商業模式九個構面有如齒輪協作,從構面中定位其經營上的主要核心,其他構面則是凝聚此核心進行營運。地區性的團隊與大型團隊在經營上各有特色,從價值導向到需求導向再到供給導向,這裡面包含了許多的關鍵項目,與財務導向有非常大的關連性,一個完整的商業模式能以利團隊永續經營。[[abstract]]This research cuts into the business situation of dance troupes in the field of performing arts with a business model, and makes an in-depth discussion from this direction. Taiwan's performing arts has not been recognized as an industry for a long time, but according to the annual report of Taiwan's cultural and creative industries, performing arts groups (including music, dance, modern drama, and traditional drama) have had numerous activities over the years and have been identified as non-profit The performance groups organized are responsible for their own profits and losses, and with the changes in the general environment, such as the raging epidemic in recent years, the performance groups have changed their business models. However, there are still workers who insist on pursuing performing arts. Gain experience and keep going with the team.The business model seems to have nothing to do with performing arts, but if we can use the logical thinking of the business model to look at the operation of performing arts groups, will we be able to achieve excellent sustainable business performance? This study takes the business model theory as the core, extends the business model canvas to construct the "performing arts business model canvas review table" as a research tool, and tries to introduce dance troupes in the performing arts field to check their business profiles, and select dance troupes in the central region by intentional sampling , including Taichung Jizhi Physical Dance Troupe and Nantou Xinchuan Dance Troupe, and compared the successful performance groups Cloud Gate Dance Theater and Zhu Zongqing Percussion Orchestra with case studies, using this research tool to deeply explore the team's business model management, providing regional dance troupes with future business policy.The study found that, whether it is a regional team or a stable operation team, using a business model to carry out performing arts groups, the problems can be clearly found through nine dimensions. The nine facets of the business model work like gears, from regional teams to large teams with their own characteristics in operation, from value-oriented to demand-oriented to orientation-oriented, which includes many key items, which are very different from financial orientation Great relevance, a complete business model can benefit the sustainable operation of the team

    [[alternative]]Effect of Hypothermia Therapy for Traumatic Brain Injury Patients: Systematic Review

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    [[abstract]]背景:臨床上創傷性腦損傷病患術後往往會出現出血、腫脹或水腦等合併症,導致腦組織體積增加進而導致顱內壓上升,治療方式之一為使用低溫治療以降低因腦水腫導致的顱內壓上升。然而,現今在臨床將低溫治療應用於創傷性腦損傷病患治療的預期成效結果不一致。目的:本研究目的為探討使用低溫治療對創傷性腦損傷病患之治療成效。方法:本文以系統性文獻方式搜尋PubMed、Medline Ovid、Cochrane、CINAHL complete、和Embase等英文資料庫,以及「華藝線上圖書館CEPS/Airiti Library 中文電子資料庫」、「臺灣碩博士論文知識加值系統」中文資料庫之文獻。中文關鍵字為腦損傷、頭部外傷、低溫治療、顱內壓、死亡率;英文關鍵字為cerebrovascular trauma, brain injury, brain trauma, encephalopathy, traumatic brain hemorrhage, induced hypothermia, hypothermia therapeutic, targeted temperature management, intracranial pressure, mortality rate以及其MeSH term。經由輸入上述關鍵字搜尋資料庫至2022年12月31前已發表之文獻,去除不符合文獻納入條件之研究,並使用Cochrane Risk of Bias Tool第二版(RoB 2.0)進行文獻品質評讀,最後透過文獻統整以整合創傷性腦損傷病患使用低溫治療之成效。結果:經文獻搜尋、篩選、及評讀流程後共納入9篇隨機試驗研究。統整其研究之成效評量為測量顱內壓監測、功能性預後狀態、及死亡率。在介入成效方面,2篇研究顯示創傷性腦損傷術後患者在使用低溫治療後的功能性預後狀態有顯著改善、3篇結果實驗組創傷性腦損傷術後患者之死亡率較對照組有顯著降低、3篇研究結果顯示低溫治療對於顱內壓之緩解無論實驗組或對照組之病患均無顯著差異;此外,所有納入的研究結果顯示創傷性腦損傷術後患者早期的顱內壓無論在實驗組或對照組中皆無顯著差異。結論:經本研究發現創傷性腦損傷患者若顱內壓大於25mmHg或從腦部電腦斷層顯示腦腫或中線偏移情形使用低溫治療後對於緩解其顱內壓具有顯著成效,而在改善長期功能性預後狀態及死亡率之成效則無明顯差異,在整體住院時間無論有無使用低溫治療皆無明顯差異。低溫治療設定方式則建議介入時間須於在腦部受損6~12小時內、目標溫度設定為33~35℃、維持時間至少48小時、回溫速率以緩慢回溫速率為宜。[[abstract]]Background:Clinically, postoperative traumatic brain injury patients often have complications such as hemorrhage, swelling, or hydrocephalus, resulting in increased brain tissue volume and intracranial pressure. One treatment option is using hypothermia therapy to reduce the increase in intracranial pressure due to cerebral edema. However, the results of the clinical application of hypothermia therapy in treating traumatic brain injury patients are inconsistent. Purpose: The purpose of this study aimed to integrate the effects of hypothermia therapy on traumatic brain injury patients.Methods:This article systematically searched English databases such as PubMed, Medline Ovid, Cochrane, CINAHL Complete, Embaseu, and "Huayi Online Library CEPS/Airiti Library Chinese Electronic Database", "Taiwan Master and Doctoral Dissertation Knowledge Value-Added System "Documents of the Chinese Database. Chinese keywords were brain injury, head trauma, hypothermia therapy, intracranial pressure, and mortality; English keywords were cerebrovascular trauma, brain injury, brain trauma, encephalopathy, traumatic brain hemorrhage, induced hypothermia, hypothermia therapeutic, targeted temperature management, intracranial pressure, mortality rate, and its MeSH term. The above keywords were entered to search the databases for published literature before December 31, 2022. Studies that did not meet the inclusion criteria in the literature were removed. The second edition of the Cochrane Risk of Bias Tool (RoB 2.0) was applied for literature quality evaluation. Finally, the literature review was integrated to examine the effectiveness of hypothermia therapy in patients with traumatic brain injury.Results: A total of 9 randomized controlled trials articles were included. According to the studies, outcome measures included intracranial pressure monitoring, functional prognostic status, and mortality. Regarding the effectiveness of the intervention, two studies showed significant improvement in functional outcome status of post-traumatic brain injury patients treated with hypothermia. The results of 3 papers showed that compared with the control group, the mortality rate of patients with traumatic brain injury in the experimental group was significantly reduced. The results of 3 studies showed that hypothermia therapy had no significant difference in the relief of intracranial pressure, regardless of whether the patients were in the experimental or control groups. In addition, the results of all the included studies showed no significant difference in the early intracranial pressure of patients after traumatic brain injury, whether in the experimental or control groups.Conclusion:This systematic review confirmed that if the intracranial pressure is higher than 25mmHg or brain CT shows brain swelling or midline shift, hypothermia can significantly reduce intracranial pressure. But there was no significant difference in the favorable outcomes, mortality, and overall length of hospital stay. The setting method of hypothermia therapy: after 6-12 hours after brain injury, the target temperature is set at 33-35�C, maintenance is 48 hours at least, and used a slow temperature recovery rate

    Reliability and validity of a Chinese version of the Cohen-Mansfield agitation inventory-short form in assessing agitated behaviour.

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    [[abstract]]Background: Patients with dementia often present agitated behaviors. The Cohen-Mansfield Agitation Inventory-short form (CMAI-SF) is one of the most widely used instruments to evaluate agitated behaviors that affect patients' quality of life and impose burden on caregivers. However, there is no simplified Chinese version of the CMAI-SF (C-CMAI-SF) in clinical settings. Purpose: This study aimed to develop a Chinese version of the C-CMAI-SF and examine its validity and reliability. Methods: This cross-sectional study included three phases. In Phase I, the original CMAI-SF was translated to Chinese. In Phase II, experts were invited to examine the content validity index (CVI). Phase III was conducted to test the validity and reliability of the C-CMAI-SF. Results: The scale showed good validity and reliability with a scale-level CVI of 0.89, Cronbach's alpha (measure of internal consistency) of 0.874, and test-retest correlation coefficient of 0.902 (for 257 individuals). Using factor analysis, three factors were identified. Regarding concurrent validity, the C-CMAI-SF score was correlated with the Neuropsychiatric Inventory (agitation aggression subscale) and the Cornell Scale for Depression in Dementia (agitation subscale). Conclusions: The study demonstrated that the C-CMAI-SF is a valid and reliable instrument for evaluating agitated behaviors in people with dementia. Relevance to clinical practice: The C-CMAI-SF is an easy and quick tool used to identify and evaluate agitated behaviors in busy clinical settings

    探究不同的教學語言及訓練教學方案對外籍照顧服務員口腔照 護學習成效之影響

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    [[abstract]]臺灣高齡者的長期照護工作多仰賴外籍照顧服務員,然因其工作繁重,受限於時間及母語講師人力的缺乏,職前訓練與在職訓練均有所不足。本研究目的即在設計出一套適合外籍照顧服務員的在職訓練方案,解決資源限制的問題,且能因應其語言不熟悉的障礙提升教學成效。本研究採類實驗設計,以臺北市、新北市及基隆市住宿式長期照顧機構325位外籍照顧服務員為研究對象,參與者被分為四組,接受不同的在職訓練方案,並於在職訓練前、後進行口腔照護能力相關認知、情意及技能的評估。四種不同的在職訓練方案由教學語言(母語/華語)與訓練教學方案(互動式多媒體教學法/傳統式課堂教學法)兩個變項所構成,分別為:母語互動式多媒體教學組、華語互動式多媒體教學組、母語傳統式課堂教學組、華語傳統式課堂教學組。結果發現使用外籍照顧服務員的母語教學有相對的教學成效優勢,其全面性的學習成效較佳。其次,不同教學方式在認知、情意及技能向度上會展現不同的優勢:互動式多媒體教學法在認知及技能向度上較傳統式課堂教學法佳;若欲使用華語教學提升情意向度的學習成效,則傳統式課堂教學法較互動式多媒體教學法具有優勢。根據本研究的發現,建議實務上應隨著在職訓練的目標彈性地調整教學法,選用合適的教學法能使有限的資源於照護在職訓練工作上發揮最大的效用

    Changes in Periodic Limb Movements of Sleep After the Use of Continuous Positive Airway Pressure Therapy: A Meta-Analysis

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    [[abstract]]Background: Both obstructive sleep apnea (OSA) and periodic limb movements of sleep (PLMS) are common in the sleep laboratory. The severity of OSA can be improved by using continuous positive airway pressure (CPAP). However, increasing evidence has shown an elevated periodic limb movement index (PLMI) in patients with OSA who use CPAP, although the pathophysiology is still unknown. This meta-analysis aimed to investigate changes in PLMS after using CPAP and the potential pathophysiology of these changes. Methods: Clinical trials in adult humans investigating the comorbidity between PLMS and CPAP were identified and analyzed using random-effects model meta-analysis. Results: This meta-analysis included 14 studies comprising 2,938 patients with OSA. The PLMI was significantly increased after using CPAP with a difference in means of 1.894 (95% confidence interval = 0.651-3.138, p = 0.003). Subgroup analysis showed that CPAP was only significantly associated with an increase in PLMI in the patients without PLMS at baseline (p = 0.045) and in those with a baseline body-mass index <30 kg/m2 (p = 0.045). The use of CPAP, apnea-hypopnea index, and arousal index were positively correlated with changes in PLMI. Conclusion: These characteristics may serve as qualitative predictive indicators of changes in PLMI after CPAP usage. Further analysis of the quantitative relationships between PLMI and the predictive indicators may be warranted

    Effectiveness and acceptability of noninvasive brain and nerve stimulation techniques for migraine prophylaxis: a network meta-analysis of randomized controlled trials

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    [[abstract]]Background: Current pharmacologic prophylactic strategies for migraine have exhibited limited efficacy, with response rates as low as 40%-50%. In addition to the limited efficacy, the acceptability of those pharmacologic prophylactic strategies were unacceptable. Although noninvasive brain/nerve stimulation strategies may be effective, the evidence has been inconsistent. The aim of this network meta-analysis (NMA) was to compare strategies of noninvasive brain/nerve stimulation for migraine prophylaxis with respect to their effectiveness and acceptability. Methods: The PubMed, Embase, ScienceDirect, ProQuest, ClinicalTrials.gov , ClinicalKey, Cochrane CENTRAL, Web of Science, and ClinicalTrials.gov databases were systematically searched to date of June 4th, 2021 for randomized controlled trials (RCTs). Patients with diagnosis of migraine, either episodic migraine or chronic migraine, were included. All NMA procedures were conducted under the frequentist model. Results: Nineteen RCTs were included (N = 1493; mean age = 38.2 years; 82.0% women). We determined that the high frequency repetitive transcranial magnetic stimulation (rTMS) over C3 yielded the most decreased monthly migraine days among all the interventions [mean difference = - 8.70 days, 95% confidence intervals (95%CIs): - 14.45 to - 2.95 compared to sham/control groups]. Only alternating frequency (2/100 Hz) transcutaneous occipital nerve stimulation (tONS) over the Oz (RR = 0.36, 95%CIs: 0.16 to 0.82) yielded a significantly lower drop-out rate than the sham/control groups did. Conclusions: The current study provided a new direction for the design of more methodologically robust and larger RCTs based on the findings of the potentially beneficial effect on migraine prophylaxis in participants with migraine by different noninvasive brain/nerve stimulation, especially the application of rTMS and tONS. Trial registration: CRD42021252638. The current study had been approval by the Institutional Review Board of the Tri-Service General Hospital, National Defense Medical Center (TSGHIRB No. B-109-29)

    Pfizer-BioNTech COVID-19 vaccine associated tinnitus and treatment with transcranial magnetic stimulation

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    [[abstract]]Learning points for clinicians This case report aimed to remind the clinicians of the potentially alternative treatment to manage the cochleopathy after the administration of the Pfizer–BioNTech coronavirus disease 2019 (COVID-19) vaccine. The repetitive transcranial magnetic stimulation might be beneficial to manage the immune reaction-associated cochleopathy

    The Dose and Duration-dependent Association between Melatonin Treatment and Overall Cognition in Alzheimer's Dementia: A Network Meta- Analysis of Randomized Placebo-Controlled Trials

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    [[abstract]]Background: While Alzheimer's dementia (AD) has a prevalence as high as 3-32% and is associated with cognitive dysfunction and the risk of institutionalization, no efficacious and acceptable treatments can modify the course of cognitive decline in AD. Potential benefits of exogenous melatonin for cognition have been divergent across trials. Objective: The current network meta-analysis (NMA) was conducted under the frequentist model to evaluate the potential beneficial effects of exogenous melatonin supplementation on overall cognitive function in participants with AD in comparison to other FDA-approved medications (donepezil, galantamine, rivastigmine, memantine, and Namzaric). Methods: The primary outcome was the changes in the cognitive function [measured by mini-mental state examination (MMSE)] after treatment in patients with Alzheimer's dementia. The secondary outcomes were changes in the quality of life, behavioral disturbance, and acceptability (i.e., drop-out due to any reason and rate of any adverse event reported). Results: The current NMA of 50 randomized placebo-controlled trials (RCTs) revealed the medium-term lowdose melatonin to be associated with the highest post-treatment MMSE (mean difference = 1.48 in MMSE score, 95% confidence intervals [95% CIs] = 0.51 to 2.46) and quality of life (standardized mean difference = -0.64, 95% CIs = -1.13 to -0.15) among all of the investigated medications in the participants with AD. Finally, all of the investigated exogenous melatonin supplements were associated with similar acceptability as was the placebo. Conclusion: The current NMA provides evidence for the potential benefits of exogenous melatonin supplementation, especially medium-term low-dose melatonin, in participants with AD

    Travel for survive! Identifying the antecedents of vaccine tourists' travel intention: Using a stimulus-organism-response model

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    [[abstract]]The COVID-19 global pandemic and the uneven distribution of vaccines have resulted in alternative medical tourism, vaccine tourism. The purpose of this study is to identify the antecedents of vaccine tourists' travel intention. The Stimulus-organism-response model was used as a framework to understand the relationship between risk perception (stimulus), pandemic prevention attitude (organism), decision making (organism), and travel intention (response) in vaccine tourism. An online questionnaire survey method was adopted to address the purpose of the research. Purposive and snowball sampling were used to select eligible respondents who were over 18 years old and had experience in vaccine tourism. A total of 520 online questionnaires were collected, and description analysis, confirmatory factor analysis, and structural equation modeling were utilized to analyze the collected data. The findings indicated that pandemic prevention attitude is a full mediator between risk perception and travel intention. There is a significant causal relationship between risk perception and pandemic prevention attitude and between pandemic prevention attitude and travel intention. Furthermore, tourists' travel decision-making also significantly influences their travel intention. However, the relationship between tourists' risk perception and travel decision-making has no significant effect. Vaccine tourism was created based on the COVID-19 context. Therefore, in order to avoid vaccine travel becoming an infection control breach, pandemic prevention planning and the medical quality of the destination, and the prevention policies between the countries should be completely assessed and conducted

    An overview of artificial intelligence techniques for diagnosis of Schizophrenia based on magnetic resonance imaging modalities: Methods, challenges, and future works

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    [[abstract]]Schizophrenia (SZ) is a mental disorder that typically emerges in late adolescence or early adulthood. It reduces the life expectancy of patients by 15 years. Abnormal behavior, perception of emotions, social relationships, and reality perception are among its most significant symptoms. Past studies have revealed that SZ affects the temporal and anterior lobes of hippocampus regions of the brain. Also, increased volume of cerebrospinal fluid (CSF) and decreased volume of white and gray matter can be observed due to this disease. Magnetic resonance imaging (MRI) is the popular neuroimaging technique used to explore structural/functional brain abnormalities in SZ disorder, owing to its high spatial resolution. Various artificial intelligence (AI) techniques have been employed with advanced image/signal processing methods to accurately diagnose SZ. This paper presents a comprehensive overview of studies conducted on the automated diagnosis of SZ using MRI modalities. First, an AI-based computer aided-diagnosis system (CADS) for SZ diagnosis and its relevant sections are presented. Then, this section introduces the most important conventional machine learning (ML) and deep learning (DL) techniques in the diagnosis of diagnosing SZ. A comprehensive comparison is also made between ML and DL studies in the discussion section. In the following, the most important challenges in diagnosing SZ are addressed. Future works in diagnosing SZ using AI techniques and MRI modalities are recommended in another section. Results, conclusion, and research findings are also presented at the end

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