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有効成分配合温熱カイロの相乗効果による局所血流増加及び皮膚感覚の変化
Get PDF目的:温罨法の効果を高めつつ、不快な刺激感を減らす有効成分の調整法を探るため、本研究では、温度受容体アゴニストであるカプサイシン、l-メントール、ジンジャーエキスを配合した温熱カイロが血流増加や皮膚刺激感にもたらす影響を検討する。方法:健康成人男女6名の前腕部または腰部に有効成分配合温熱カイロを貼付し、局所の皮膚血流と筋血流の変化を測定した。同時に被験者が自覚した皮膚感覚についても点数化した。結果:カプサイシン配合温熱カイロでは皮膚血流増加の相乗効果がみられたものの、ピリピリとした皮膚刺激感も上昇した。l-メントールとジンジャーエキスを配合した温熱カイロでは、特に筋血流増加において相乗効果が生じた一方で、不快な皮膚刺激感は抑制された。考察・結論:配合成分の組み合わせを調整することによって、温罨法における血流改善効果の増強と不快な皮膚刺激感の抑制を最適化できる可能性がある。博士（医学）旭川医科大
Comparison of right ventricular function between three-dimensional transesophageal echocardiography and pulmonary artery catheter （３次元経食道心エコーと肺動脈カテーテルによる右心機能測定の比較
Get PDFObjective: This study aimed to compare measurements of right ventricular function using three-dimensional transesophageal echocardiography (3D TEE), and pulmonary artery catheters (PACs) in patients undergoing cardiac surgery. The authors examined the practicality of using the 3D TEE.
Design: Prospective observational.
Setting: Cardiac operating room at a single university hospital.
Participants: All adult patients undergoing elective cardiac surgery at a single tertiary care university hospital over two years.
Interventions: None.
Measurements and main results: Right ventricular end-diastolic volume (RVEDV), right ventricular end-systolic volume (RVESV), stroke volume (SV), and right ventricular ejection fraction (RVEF) were measured with both 3D TEE and PACs. Assessments were performed using correlation coefficients, paired t tests, and Bland-Altman plots. Thirty-one patients participated in this study. Each measurement showed good agreement. RVEDV and RVESV were slightly lower on 3D TEE than on PAC (205.9 mL v 220.2 mL, p = 0.0018; 143.0 mL v 155.5 mL, p = 0.0143, respectively), whereas no significant differences were observed for SV and RVEF (31.0% v 31.1%, p = 0.0569; 61.6 mL v 66.9 mL, p = 0.92, respectively). Linear regression analysis showed high correlation between 3D TEE and PAC for RVEDV (r = 0.87) and RVESV (r = 0.81), and moderate correlation for SV (r = 0.67) and RVEF (r = 0.67). In the Bland-Altman plot, most patients were within the 95% limits of the agreement throughout all measurements.
Conclusion: A high correlation was found between measurements made with a PAC and with 3D TEE in the assessment of right ventricular function. Three-dimensional TEE would be a potential alternative to PAC for assessment of right ventricular function during intraoperative periods
