Karlsruhe Institute of Technology

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    The Improvement Function Reformulation for Graphs of Minimal Point Mappings

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    Graphs of minimal point mappings of parametric optimization problems appear in the definition of feasible sets of bilevel optimization problems and of semi-infinite optimization problems, and the intersection of multiple such graphs defines (generalized) Nash equilibria. This paper shows how minimal point graphs of nonconvex parametric optimization problems can be enclosed with the help of well structured problems with additional parameters. This enclosure coincides with the minimal point graph under mild assumptions. We specify our results to the setting of generalized Nash equilibrium problems. This well structured formulation of the enclosure makes it accessible to approximations by branch-and-bound methods. We provide corresponding numerical results in a separate paper

    Keynote: Open Wearable Computer Systems and Applications

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    This keynote addresses the simplified access of sensor technologies and machine learning in the field of wearable computing, highlighting important contributions of the OpenEarable project and EdgeML. The aim is to achieve the lowest possible utilisation threshold so that even complex research and development projects in the field of wearable computing can be carried out quickly and easily, with the area of application being human activity recognition (HAR), but also more specific areas. In my presentation, I will focus in particular on the area of health

    Probing the Dynamics and Configurations of Single-Molecule Junctions via Seebeck Coefficient Spectroscopy

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    Single-molecule junctions exhibit dynamic structural configurations that strongly influence their electronic and thermoelectric properties. Here, we combine conductance (G) and Seebeck coefficient (S) measurements using the novel AC-based scanning tunneling microscope break-junction technique to probe the real-time evolution of oligo(phenylene ethynylene) molecular junctions. We show that most junctions undergo configuration changes that lead to notable changes in S, while G remains nearly constant. Density functional theory and quantum transport simulations link these observations to variations in contact geometry and charge transfer at the molecule–electrode interface. Our results demonstrate that simultaneous G and S measurements enable direct access to the dynamic reconfiguration of single-molecule junctions and offer design insights for thermoelectric molecular devices and new routes for increasing single-molecule junction stability

    Assessment of ground-motion prediction equations using observations and information theory: application to the Northeastern Tibetan Plateau

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    Ground-motion prediction equations (GMPEs) are fundamental to seismic hazard assessment, yet their applicability is difficult to evaluate in tectonically complex regions where instrumental observations are sparse or absent, such as the northeastern Tibetan Plateau. We evaluate representative GMPEs using two approaches: residual-based error metrics and an information- theory-based evaluation. The two recent earthquakes, the 2022 Menyuan and 2023 Jishishan events, provide an opportunity to examine model behavior under observed conditions. The information- theory-based approach is first applied to these two earthquakes to verify feasibility and to compare with residual-based outcomes, and is then extended to two large historical earthquakes in the region, the 1920 Haiyuan earthquake and the 1927 Gulang earthquake, to assess stability under extrapolative, data-limited conditions. Across these applications, the information-theory-based evaluation yields consistent rankings and stable weights, whereas the residual analysis captures event-specific variability. Together, the two approaches provide complementary insight into model applicability and offer a practical basis for ground-motion assessment and extrapolation in tectonically complex and observationally sparse regions

    BFO DPS310 Barometer

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    We describe an autonomously recording barometer which can resolve ambient atmospheric pressure variations for signal periods longer than 30 seconds, operates on a single Lithium D-cell battery for 6 months and maintains absolute time by synchronizing with the DCF77 radio clock signal available over much Europe. Its weight is 180 g and fits into a 500 ml twist top jar. The barometer should be well suited for research in meteorology and geophysics

    Reprogramming the Metastatic Niche in Pancreatic Cancer by Targeting CD44 on Bone Marrow-Derived Cells

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    Occurrence of seeding multi-layer clouds in the Arctic from ground-based observations

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    Studies of Arctic clouds often focus on low-level single-layer clouds (SLCs). Here, we use combined observations of soundings and cloud radar during the MOSAiC, ACSE, and AO2018 research cruises as well as from long-term observations at Ny-Ålesund, Svalbard and Utqiagvik, Alaska to investigate the occurrence of SLCs and multi-layer clouds (MLCs) in the Arctic and to assess the rate of ice-crystal seeding in cold MLCs. MOSAiC observations show cloudy conditions in between 70 % and 90 % of sounding-radar cases. SLCs show occurrence rates of 30 % to 40 % with the highest value of 45 % during October. Cold MLCs are most abundant from November to June (40 % to 55 % of cases). Seeding occurs in about half to two thirds of the identified cold MLCs during MOSAiC for which the sub-saturated layer extends between 100 and 1000 m. The seeding rate increases by as much as 20 percentage points as the assumed size of the falling ice crystals is increased from 100 to 400 µm. The observations reveal a stable rate of cloud-free conditions of around 20 % over the covered latitude range. Cloud occurrence during MOSAiC and at Ny-Ålesund in July, when the geographical distance between observations was minimal, shows reasonable agreement. Comparisons of MOSAiC and other research cruises to the central Arctic also indicate consistent occurrence rates of different cloud types despite the likely effect of year-to-year variability. The comparison of data from ship campaigns and land sites suggests that the latter are not necessarily a good indicator of cloud occurrence in the high Arctic

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