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Pacific RxTracts - December 2025
Articles: FDA Approves Nerandomilast: A New Era in Idiopathic Pulmonary Fibrosis Treatment Brand New Approach to Addressing the Unmet Need of Cholestatic Pruritus Prep for Success with Lactulose Caution with Reported Allergies: Increased Risk of Surgical Site Infection with Non-β-Lactam Antibiotics Eltrombopag Redefines Treatment for Newly Diagnosed Pediatric ITP Combination for Extensive-Stage Small Cell Advancing Treatment for HER2-Positive Breast Cancer: Trastuzumab Deruxtecan plus Pertuzumab Comparison in Efficacy of Abiraterone and Enzalutamide in US Veterans with mHSPC Revumenib: A First-in-Class Menin Inhibitor for Relapsed or Refractory Acute Myeloid Leukemia Ziftomenib: A Menin Inhibitor Redefining Precision Therapy in NPM1-Mutated AML The Future of Convenient Obesity Treatment Optimizing Glycemic Control in Pregnancies The Rise of Dual Neurokinin Blockade: Elinzanetant as a Novel Solution for VMS Balancing Symptom Relief and Survival in Dementia Hospice Medication Management Enlicitide: The First Oral PCSK9 Therapy in Phase 3 Evaluationhttps://scholarlycommons.pacific.edu/rx-tracts/1011/thumbnail.jp
Letter from Henry C. Robinette to Brother, 1863 April 12
Henry Clay Robinette, attended the Delaware Military Academy (1857-1860) and joined the Union Army at the outset of the Civil War. H.C. Robinette fought at the battles of Corinth and Vicksburg (1862) and was later on the General Grant\u27s staff (1864-1865). After the war he was court-martialed for cursing an officer in a barroom brawl (1867)but his father petitioned President Andrew Johnson on his behalf with the result that his sentence was commuted and he was promoted to brevet major for gallant and meritorious services at the Battle of Corinth and the siege of Vicksburg.https://scholarlycommons.pacific.edu/civil-war/1024/thumbnail.jp
Letter from Henry C. Robinette to Done?, 1867 February 13
Henry Clay Robinette, attended the Delaware Military Academy (1857-1860) and joined the Union Army at the outset of the Civil War. H.C. Robinette fought at the battles of Corinth and Vicksburg (1862) and was later on the General Grant\u27s staff (1864-1865). After the war he was court-martialed for cursing an officer in a barroom brawl (1867)but his father petitioned President Andrew Johnson on his behalf with the result that his sentence was commuted and he was promoted to brevet major for gallant and meritorious services at the Battle of Corinth and the siege of Vicksburg.https://scholarlycommons.pacific.edu/civil-war/1028/thumbnail.jp
The Effectiveness of Cognitive Behavioral Therapy (CBT) and Medication for Treating Major Depressive Disorder in Adults 18-45 and Factors Contributing to Treatment Resistance: A Case Series.
Cognitive behavioral therapy (CBT) and antidepressant medications are often used to treat major depressive disorder (MDD). After examining the existing research on the treatment of MDD, a study was conducted using a vignette methodology to determine if there is a decreased rate of symptoms for patients who are currently being treated for MDD by a mental health professional utilizing CBT and antidepressant interventions. The study explored the effectiveness of CBT in reducing depressive symptoms when antidepressants alone had limited efficacy. The target population included adult patients experiencing MDD, with some presenting additional challenges such as cultural barriers, difficult diagnoses, and medication compliance issues. The research study’s participants were three patients who were receiving treatment at an outpatient counseling facility and exhibited resistance to MDD treatment despite taking antidepressants. Factors that could have created this resistance were analyzed as part of the study. Each patient’s unique circumstances and treatment plans were also analyzed. After reviewing the study’s data, the research indicated that although there were some regressions or setbacks during treatment, CBT was able to reduce symptoms of MDD for patients who still had symptoms after taking antidepressant medication
How Allusion Enhances Consumer Response to Hope Appeals in Health Messaging
While fear appeals often appear in health-oriented Public Service Announcements (PSAs), three experiments demonstrate that a positive appeal, hope, can be effectively used in PSAs to promote healthy eating when combined with an allusion, a type of figurative language. Specifically, Study 1 uses eye-tracking to establish that allusion moderates hope’s encouragement of visual attention and engagement. Study 2′s experiment illustrates how allusion moderates hope’s influence on message outcomes. Study 3 tests whether self-efficacy mediates the relationships between hope and allusion on message outcomes using Hayes PROCESS modeling. Results support self-efficacy’s mediation of the hope-allusion interaction on message response outcomes. One contribution is the investigation of a multimodal allusion incorporating both visual and verbal elements and its ability to enhance message effectiveness. This study also advances the theoretical understanding of the use of positive emotional appeals and the power of self-efficacy to account for their effects in health promotion PSAs
Unfolding Futures: Claudia Landeen School
The Unfolding Futures initiative aims to foster creativity and mental health awareness by engaging students of Claudia Landeen School in origami crafts and goal-setting activities. According to the “Creating arts and crafting positively predicts subjective wellbeing” article published under the National Library of Medicine, “Creative arts are also associated with improved self-esteem and emotion regulation, and provide a means of authentic self-expression” (Keyes, Helen et al.). We strive to engage students between 2nd and 6th grade within the After School Education and Safety (ASES) program in organized origami crafting with the goal of utilizing crafts as an outlet for their mental health. Alongside mental health, the activity aims to foster creativity and S.M.A.R.T. goal setting by having students write personal goals on a slip of paper and fold them to their desired form. Final origami creations will be displayed in the ASES classrooms and at the completion of the project students will be returned their S.M.A.R.T. goals for reflection. Each student will have a choice of 3 select origami templates with varying difficulties while learning and given freedom to write their own S.M.A.R.T. goals. S.M.A.R.T. goals are goals that are specific, measurable, attainable, relevant, and time-based. Learning and enforcing S.M.A.R.T. goal setting prepares students for persevering through adversity and developing foresight. The initiative addresses and emphasizes the importance of goal setting and creative expression, ultimately aiming to uplift students’ mental health and mindfulness
Seasons
This series of wire sculptures represents the four seasons; spring, summer, fall, and winter, through the symbolism of flowers. Each piece reflects the essence of its respective season, allowing the viewer to connect with personal memories and moments associated with nature’s changing rhythms. By using flowers as a medium, I hope to evoke emotions and memories tied to special times in life.
Nature has always been a significant source of inspiration in my work. In this project, I focused on flowers as symbols of growth, transformation, and the passage of time. The irregular, organic shapes of the wire sculptures reflect the unpredictable nature of life and the ever changing beauty of the seasons. Though made from wire, the flowers maintain a delicate, fragile quality, much like the moments they represent.
Each flower is meant to remind the viewer of moments in their own life. Cherry blossoms symbolizes renewal, sunflower speaks to warmth and vitality, cosmos represents change, and camellia captures stillness and reflection. These wire works are not just representations of nature; they are emotional markers, inviting viewers to reflect on their personal connections to each season.
Through this work, I aim to celebrate the beauty of life’s fleeting moments, using flowers to bridge the gap between nature, memory, and emotion. My hope is that these wire sculptures will encourage the viewer to reflect on their own experiences, finding meaning in the flowers that symbolize the seasons of their lives
Cuộc Đời (A Lifetime)
My series, “Cuộc Đời” or “A Lifetime” captures the difficulties I faced as a student during the past few years. I was met with an uphill battle to graduate while dealing with many personal, financial, and health problems. While working on my series, I felt a lot of longing to be free from everything, while feeling content with where I am in life. This year, I challenged myself with learning how to stretch my own canvases, using a new medium, oil paint, and working large (6 ft x 4ft). Unexpectedly, I came across another challenge; my dominant hand was significantly inflamed. The only remedy to help heal my wrist was to not use it at all. I resolved this by using my left hand. With all of these challenges in mind, I persevered. Just like life, setbacks encourage me to move forward. On an everyday basis, I am physically and mentally overloaded with work and school. Somehow, I need to keep my composure and calm amongst the chaos. In my paintings, I make expressive and deliberate, yet delicate, marks that create movement throughout the composition. The colorful palette I use and the energy of each stroke I make juxtapose the heavy feelings of anxiety, pain, and agony I experience daily. I want the difficulties to end so badly, but I know that everything is working in my favor in the long run if I just keep going. My art is my therapy. Every project I have done encouraged me to continue my artist journey. Doing art is the reason why I continue to be creative, fun, and have a positive mindset. Without the support of my professors, advisors, my friends, and my family, I would not be where I am today. I express my gratitude to anyone who has come across my life, as they influenced me as an artist no matter where I go. “Đi đường nào thì cũng tới đó” - “It might take a little longer, but you’ll get there to where you’ll need to go no matter which path you take”. Painting Name Labels “ Sắp Tới” (Almost there) “ Xong Chưa?” (Done Yet?) “ Giữ gìn sức khỏe” (Maintain Your Health) “ Hết Pin ” (Out of battery) “ Chết Với Nụ Cười (To Die with a Smile