49112 research outputs found
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Diritto all’informazione e alla conoscenza: il ruolo dell’educazione
No full textLa società attuale, caratterizzata dal dominio delle tecnologie di informazione e comunicazione (ICT), si distingue per un’elevata intensità di informazione e conoscenza, le quali costituiscono i principali fattori di sviluppo e benessere individuale e collettivo. Benché siamo immersi in un ambiente informazionale e, grazie all’impiego di dispositivi sempre più avanzati, la maggior parte delle persone abbia un facile e rapido accesso a una mole di dati pressoché illimitata, una tale fruizione di contenuti non si traduce necessariamente in una democratizzazione del sapere. Ciò avviene, ad esempio, a causa di fenomeni riconducibili al cosiddetto disordine informativo, quali disinformazione e misinformazione, che ostacolano il diritto all’informazione e alla conoscenza e, di conseguenza, minano la possibilità di una piena partecipazione sociale in direzione democratica. Da questo punto di vista, si crede che l’educazione possa assumere un ruolo fondamentale nel garantire un tale diritto; in questo senso, si auspica un rinnovato impegno per un’autentica educazione alla ragione che, nella direzione della formazione della persona e del cittadino, assuma come mete pedagogiche prioritarie lo sviluppo del pensiero critico e della consapevolezza epistemica, i quali strutturano abiti mentali essenziali per il cittadino del XXI secolo
Nanocarrier-Based Delivery Systems for Natural Compounds Across Research Stages
No full textNatural compounds such as polyphenols, flavonoids, and terpenoids have long been explored for their therapeutic potential. They can act as antioxidants, limit inflammation, and influence cancer or neurodegenerative pathways. However, these benefits rarely translate directly into medical practice, as their solubility is poor, chemical stability is fragile, and metabolism is too fast. In recent years, nanotechnology has offered an alternative route. A wide range of materials, polymeric, inorganic, hybrid, or responsive to external stimuli, were designed to protect and deliver such molecules. Each platform features different preparation methods and release behaviors; all intended to extend circulation and increase tissue selectivity. Considerable attention was paid to targeting strategies, both passive and ligand-mediated, that enhance accumulation in diseased tissues. Preclinical studies have confirmed that encapsulation can raise the therapeutic index of phytochemicals against various conditions, including cancer, inflammation, microbial infections, and neurodegeneration. Still, translation to the clinic is far from resolved, limited by uncertainties over safety, manufacturing scale, and regulation. A parallel line of research now investigates biomimetic carriers, including vesicles derived from red blood cells and whole erythrocytes, which offer immune evasion and versatile loading capacity. The convergence of nanotechnology and natural product pharmacology, enriched by such biologically inspired designs, may open the way to more precise, multifunctional, and patient-tailored therapies
Giulio Di Donato, «Vera democrazia»: politica e diritto nella prospettiva marxiana, Torino, Giappichelli, 2025.
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La discussione di tesi filosofiche di Maria Lucrezia Giastefia Conti (Napoli, 1644)
No full textIn 1644 (or perhaps 1645), the young Maria Lucrezia Giastefia Conti (ca. 1629-1657) publicly defended her philosophical theses before the viceroyal court of Naples. On the occasion of this event, which was quite rare for the time, a pamphlet was published containing both the text of the prefatory speech that the student delivered before the discussion—a rhetorical exercise related to the querelle des femmes—and the Aristotelian-based philosophical theses defended. This chapter analyzes the content of the printed work, highlighting, among other things, the distance between the purely scholastic approach of the theses and the Platonic inspiration that emerges from some passages of the preface. Additionally, it provides some information about the life of the protagonist of the event, which took place within the orbit of the Colonna family
Gli studi di Marta Fattori su censura e filosofia moderna. Acquisizioni e prospettive di ricerca
No full textSmall localities, large conflicts: radical right parties and the politics of integration policymaking in two European medium-sized towns
No full textIntegration policies emerged as a critical focus of local policymaking in smaller towns, driven not only by migration trends in these areas, but also by the growing political influence of local radical right parties (RRPs). This trend occurred across various European countries, including Belgium and Italy, raising new questions about the impact on policy formation of locally embedded RRPs and the social and political polarisation dynamics which foster their growth. Despite growing scholarly attention to the role of local actors in shaping integration policies, these dynamics have mostly been studied in large cities. Therefore, this article aims to explore the effects of RRPs’ rise on integration policies in Ninove (Belgium) and Fermo (Italy), two diversifying and deindustrialising medium-sized towns governed by liberal coalitions, but with a strong opposition presence of RRPs. Adopting a comparative perspective, it utilises document analysis of national and local integration policymaking, complemented by 34 interviews with local actors. The results show that RRPs shape local agenda setting and local governing parties respond by creating policy ambiguity around policies targeting migrants. Specifically, they invest in policies that aim to support integration, but make sustained attempts to disguise that migrants are the target population for these policies
The strength of stance: The impact of brand activism on resistance to negative information, purchasing, and premium paying intents across different types of failures
No full textThis paper represents a pioneering exploration of how brand activism influences consumer responses to performance and value-related failures. Specifically, across two experiments, the research explores how brand
activism influences consumer resistance to negative information, purchase intent, and willingness to pay more, in
response to product, service, and value-related failures. Study 1 (N = 237) reveals that consumers who are more
involved in activism and are exposed to a product failure from activist brands exhibit higher resistance to
negative information compared to those who encounter product failures from non-activist brands. This suggests
that activist branding may protect companies by cultivating a resilient, loyal consumer base in such adverse
situations. Study 2 (N = 261) extends these findings by examining whether value-related (vs service-related)
failures impact the buffering effect generated by a brand’s activist stance. Results indicate that activist brands
particularly benefit from a protective buffer in the context of service failure scenarios. However, this buffer does
not extend to value-related failures, leading to harsher consumer judgments and intentions. The research
significantly contributes to brand activism literature by uniquely integrating the themes of brand activism and
brand transgressions, exploring how brand activism affects consumer responses to both performance and valuerelated failures
The cytotoxic/genotoxic role of impurities in soluble minerals: The case of natural (fibrous epsomite) versus synthetic (Epsom salt) magnesium sulphate
Get PDF: Epsomite and Epsom salt are very common mineral phases, and many known uses are found in agriculture, and in food and pharmaceutical industries. Natural epsomite can be fibrous and inhalable, potentially reaching the digestive tract after dissolving in mucus and saliva. Epsom salt is a common food additive (E 518) to which humans can be exposed daily, although its health effects are still debated. This study aims to (i) determine if natural epsomite (MP) and Epsom salt (SE) may be toxic to humans and (ii) identify and quantify the impurities in natural epsomite and try to ascertain their role in the toxicity of this mineral. In vitro experiments were performed on human colon epithelial cancer cells (Caco-2), enterocyte-like Caco-2-derived monolayers, human monocytic cell line THP-1, and THP-1-derived M0 macrophages. Generally, MP showed significantly higher toxicity in terms of oxidative stress, DNA damage and inflammation than SE, whose effects can be considered negligible. The higher pathogenicity of MP undoubtedly comes from the toxic elements of impurities, which are absent in pure SE. This research clarifies the role of impurities in the toxicity of natural epsomite, which may be higher than previously supposed. Moreover, considering its extensive use in the food industry, it represents a new step in assessing the safety of ingesting magnesium sulphate
From Big Farms to Big Pharma? Problematizing science-related populism
Get PDFSkepticism about health/vaccination policies during Covid-19 was considered a key example of “science-related populism” mainly based on far-right case studies. However, critics also spread among various left-wing and environmentalist milieus, which represents an understudied phenomenon. Relying on different strands of scientific literature, and on a qualitative research design aimed both to take account of the political heterogeneity within this critical area and to deepen its links with environmentalism, we aim to highlight the limits and normative implications of its interpretation as solely populism, and to contribute to the elaboration of a different interpretive model. Qualitative and frame-bridging analysis highlighted the consolidation of worldviews in clear opposition to hegemonic values, where the criticism of science finds a more appropriate explanation in a denunciation of the intrusiveness of capitalism in science production, as well as in a rejection of “reductivism” and a claim to self-determination that extend from ecological to health issues