Rajesh Varma
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Nutritional aspects in the sportsman’s functional rehabilitation program
No full textThe adoption of a proper dietary regimen is of vital importance in the sports practice of athletes, as it is able to ensure an adequate turn-over of all those substances that are consumed with exercise. Our purpose was to demonstrate how adequate protein intake can favorably influence the post-injury rehabilitation phase. Our work is presented as a case-control study on a group of 16 competitive athletes recovering from sports injuries who were prescribed a balanced diet with, to 8 of them, oral supplementation with a pool of amino acids in optimal composition in the dose of 1g/kg/day. In the two groups, recovery time, muscle strength, and injured limb diameter were taken as variables. It was observed that the group treated with amino acid supplementation had statistically significant benefits compared with the group treated with diet prescription alone.</p
Analyzing Riemann's hypothesis
No full textIn this paper we perform a detailed analysis of Riemann's hypothesis, dealing with the zeros of the analytically-extended zeta function. We use the functional equation for complex numbers s such that 0<Re(s)<1, and the reduction to the absurd method, where we use an analytical study based on a complex function and its modulus as a real function of two real variables, in combination with a deep numerical analysis, to show that the real part of the non-trivial zeros of the Riemann zeta function is equal to ½, to the best of our resources. This is done in two steps. First, we show what would happen if we assumed that the real part of s has a value between 0 and 1 but different from 1/2, arriving at a possible contradiction for the zeros. Second, assuming that there is no real value y such that ζ(1/2+yi)=0, by applying the rules of logic to negate a quantifier and the corresponding Morgan's law we also arrive at a plausible contradiction. Finally, we analyze what conditions should be satisfied by y∈ℝ such that ζ(1/2+yi)=0. While these results are valid to the best of our numerical calculations, we do not observe and foresee any tendency for a change. Our findings open the way towards assessing the validity of Riemman's hypothesis from a fresh and new mathematical perspective.</p
A remark on a perturbed Benjamin-Bona-Mahony type equation and its complete integrability
No full textIn the Letter, we study a perturbed Benjamin-Bona-Mahony nonlinear equation, which was derived for describing shallow water waves and possessing a rich Lie symmetry structure. Based on the gradient-holonomic integrability checking scheme applied to this equation, we have analytically constructed its infinite hierarchy of conservation laws, derived two compatible Poisson structure and stated its complete integrability.</p
Polyamine catabolism via spermine oxidase in the pathogenesis and treatment of hyperglycemia and diabetes mellitus-A short discussion
No full textDiabetes mellitus can be described as chronic, endocrine dysfunction of pathophysiological regulation related to glucose and insulin. Hyperglycemia is the most common and intensely related complication of this dysfunction and has countless methods of pathogenicity. Hyperglycemia has the ability to exacerbate a degenerative positive feedback loop within critical tissues. Considering the fact that pancreatic hormonal regulation has played an increasingly considerable role in serum glucose homeostasis, here we begin a discussion into the implication of polyamine catabolism as a pathway with a mechanism that would contribute considerably to the necrosis and dysfunction of islet cells in the pancreas. The pathogenicity of this mechanism focuses on how the sustained increase in free radical production by hyperglycemic induction extenuates several complications in diabetes mellitus. The oxidation of spermine to spermidine produces hydrogen peroxide, as well as 3-aminopropanol (which spontaneously converts to acrolein) and spermidine (the precursor for the substrate of this reaction). This increase in reactive oxygen species exhibits the ability to inhibit autophagy and apoptosis as well as stimulate fat necrosis within the cells of the pancreas. Considering the islet cells of the pancreas play an extremely important role in glucose homeostasis, small changes in concentrations of these ROS are able to eliminate large regulatory factors while going undetected in the analysis of disease processes and therapeutics. </p
The conclusion of the limitless hotel problem
No full textMathematician Cantor's Set theory appeared paradox and mathematical theory crisis. The famous German mathematician Hilbert used "Hilbert Hotel" to describe Cantor's Set theory paradox. At that time, people could not find a strict mathematical theory to refute Cantor's Set theory, but let everyone get used to and accept Cantor's Set theory, and thought that it was not a paradox. After the proposal of the limitless Hotel question, it caused controversy between the two parties. I quoted the definition of mathematical logic and got the correct answer.Proved that there is no paradox in limitless hotels (Reason: limitless hotels cannot increase the number of new guests staying.).A deep analysis of Cantor's limitless elements and the infeasibility of one-to-one correspondence was conducted.2020 Mathematics Subject Classification: 03G27, 03F07, 03D45, 03F55</p
Covariance edges matrix of geometric elements
No full textIn this paper, we introduce a new matrix associated with polygons and polyhedrons, namely the covariance edges matrix. We show that, for a regular polygon or polyhedron the corresponding matrix is proportional to the identity of size two or three. Based on this fact, we propose, as an application, several algebraic shape quality measures for convex polygons or polyhedrons. Furthermore, this matrix may be related to the metric of a simplex. Future studies will be devoted to the definition of the covariance edges matrix for higher elements and real applications to mesh optimisation.</p
Short implants and tooth-implant connections
No full textBoth short implants (<8mm) and tooth-implant connections are, to say the least, controversial therapeutic means. However, if we take a serious look at the data in the scientific literature, we can observe favorable clinical results in both areas, enabling these therapeutic options to be accepted as Evidence-Based Dentistry. </p
Clinical presentation, ICU management and outcome in severe COVID-19 disease – A prospective observational study
No full textAim: We conducted a prospective, observational study to describe the clinical characteristics, management, and outcomes of patients with moderate to severe coronavirus disease admitted to the Intensive Care Unit (ICU).Methods: The study was conducted from 1st July 2020 to 31st December 2020. The criteria for ICU admission included a positive Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) for the novel Coronavirus (SARS-CoV-2) and oxygen saturation of less than 90% with or without oxygen. Results: A total of 621 patients were included (median age, 59 years [interquartile range {IQR}, 48-68]; 75.8% were males. The common comorbidities were hypertension (323 [52%]), and diabetes mellitus. 96 (15.5%) patients underwent mechanical ventilation, 18 (2.9%) received renal replacement therapy, and 223 (36%) died. The median age in non-survivors was significantly higher [63 years (IQR 55-71)] vs. 57 years (IQR 46-66)] (p < 0.001). Hypoxia (oxygen saturation (SpO2 < 90%) and shortness of breath suggestive of impending respiratory failure were the most common symptoms necessitating ICU admission. A low absolute lymphocyte count (ALC), and high levels of inflammatory biomarkers which persisted for seven days after diagnosis were significantly associated with non-survival. Multivariate logistic regression analysis showed shortness of breath (SOB), hypoxia (SpO2 < 90% on oxygen), use of neuromuscular blockers, and chronic kidney disease as independent risk factors associated with mortality as were the severity scores (APACHE and SOFA). Conclusion: This single-center case series provides clinical characteristics and outcomes of patients with confirmed COVID-19 disease admitted to the COVID ICU. These findings are important for guiding research and preparing for future pandemics.</p
Antioxidant and detoxifying enzymes response of stored product insect pests to bioactive fractions of botanical extracts used as stored grains protectant
No full textRecurrent exposure of stored product insects to synthetic insecticides resulted in the development of resistance which occurs due to changes in insect metabolic enzymes. The inhibitory effect of ethyl acetate active fraction of Mitracarpus villosus, Bridelia micrantha, and Clerodendrum capitatum on antioxidant and detoxifying enzymes of stored product insects was investigated in this study. Sitophilus oryazae, Tribolium castaneum, and Rhizopertha dominica were exposed to 5 and 20 μl concentrations of ethyl acetate active fraction VI 50:50 derived from glass column chromatography in a fumigation chamber and were homogenized separately. The results showed that SOD, CAT, GPx, GSH, and GST activities were dosage-time-dependent. Adult insects exposed to different dosages of C. capitatum active fractions significantly inhibited GST and GPx activities, and SOD, CAT, and GSH activities were induced in comparison to insects in control. While, M. villosus and B. micrantha extracts exhibited a significant increase (p < 0.05) in SOD, CAT, and GSH in contrast to the inhibitory effects on GST and GPx. These results clearly show that stored beetles differ in their response to different enzymatic activities and that the evaluated plant materials may be used as an eco-friendly biopesticide in the IPM strategy for safeguarding stored food grains against stored produced insect pests.</p
Mapping crisis intervention course into social work academic curricula in Lebanon
No full textSocial work is strongly presented to support and decrease the suffering of people living in a crisis. The call to intervene professionally in such cases is highly demanded by government institutions, non-governmental organizations, international organizations, and United Nations agencies, the main umbrella that enfolded practitioner social workers in Lebanon. Although Lebanon has experienced successive crises for more than forty years, there is no national strategy for social work or for intervention during crises that must be developed by the Ministry of Social Affairs in collaboration with relevant institutions such as academia. However, considering that the Lebanese universities that graduate social workers are the most important source for developing that strategy based on evidence-based research, unfortunately, they did not do any action. The purpose of this article is to describe how these universities are preparing students and developing their capacities to deal with the crisis consequences. The focus of this article is the presence of the Crisis Intervention (CI) course in the curricula of universities. Data were collected from all Lebanese universities’ websites and catalogs with undergraduate-level social work majors (N = 6). The data were issued from reviewing the curricula of the six universities that covered the N = 290 course. Data shows that the CI course does not enclose three out of six published curricula as well and results indicate a modest appearance of the crisis and its relevant courses. Accordingly, at the end of the research, a syllabus of the crisis intervention course is proposed and will be shared with the six Lebanese concerned Universities.</p