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Bondi accretion disc luminosity around neutral and charged Simpson-Visser spacetimes
No full textWeinvestigaterelativisticBondiaccretionintheSimpson-Visserspacetime, which,
via a single parameter l, interpolates between the Schwarzschild, regular black hole, extremal
and wormhole regimes. First, we analyse the neutral Simpson-Visser geometry, recovering
Schwarzschild at l= 0, and then its charged extension of the Reissner-Nordström metric. In
both these cases, we derive the conservation equations and analyse two representative fluid
models: a barotropic perfect fluid and a constituent with an exponential density profile. By
varying the parameters across regimes, we locate critical (sonic) points and integrate velocity,
density, and pressure profiles. Although near-horizon inflow velocities are similar across the
different solutions, we find that the critical radius, as well as the resulting accretion rates
and luminosities, change significantly depending on the value of the parameter and the type
of fluid. Remarkably, the barotropic and exponential cases exhibit different trends in the
outer regions. Moreover, by extending the analysis to the charged SV spacetime, we find that
the presence of a central charge Q produces additional, albeit modest, shifts in the sonic
radius which, in combination with those induced by the regularisation parameter l, could
provide a double observational marker. In particular, while l acts predominantly on the
position of the critical point, in the barotropic fluid case, the electromagnetic contribution
of Q slightly dampens the inflow velocity near the horizon
Process Mining Meets Robotic Systems: Challenges and Opportunities
No full textRobotic systems are increasingly used in different application domains to support and automatize complex activities. The behavioral process of these systems, referred to as mission, defines the sequence of tasks enabling both robot actions and interactions. Since they can act autonomously in the environment, analysis techniques are crucial to ensure mission integrity and prevent system failures. In this context, process mining techniques can leverage data generated during robot activities to discover and analyze a robotic mission. However, robotic @systems executions are characterized by a dynamic context and behavioral abilities that strongly impact the system analysis. This chapter examines the characteristics of robotic systems and discusses their interplay with process mining to foster the effective application of process mining. It aims to identify the primary challenges and outline future research opportunities
La salute del servizio sanitario: accessibilità, equità, effettività
No full textTerza edizione del ciclo di seminari online interdisciplinari aperti a studenti, professionisti, operatori, studiosi, cittadini e a tutti quanti siano interessati ai temi proposti
Feasibility and Proof-of-Concept Evaluation on a Real-Time, Portable, Fluorescence-Based Device for Assessing Perineal Bacterial Contamination in Broodmares
No full textResearch on the reproductive tract microbiology of broodmares has primarily focused on the uterus, with a limited set of tools for the rapid detection of pathogenic bacteria in the perineal region. Accurate, real-time identification of bacterial contamination could improve the diagnosis and management of post-breeding infectious endometritis. In this proof-of-concept study, we evaluated the ability of a portable MolecuLight i:X fluorescence imaging device for the rapid, non-invasive detection of potentially pathogenic perineal bacteria in healthy broodmares, comparing results with microbiological culture as the gold standard. Using ultraviolet-induced fluorescence imaging guided for swabbing and microbiological culture, the device demonstrated 80% sensitivity, 96% specificity, and 91% accuracy in differentiating potential pathogenic from commensal bacteria in clinically healthy broodmares. These preliminary findings may represent the basis for further assessment of the real-time, fluorescence-based technology in diseased or symptomatic broodmares, potentially aiding timely clinical decision-making. Further multicentred studies with larger inclusion of mares with confirmed endometritis are needed to strengthen the relevance of this technology and to expand the device’s application in equine reproductive health
Society 5.0
No full textThis book constitutes the revised selected proceedings from the 5th International Conference on Society 5.0, Society 5.0 2025, held in San Benedetto Del Tronto, Italy, during June 25–27, 2025.
The 24 full papers presented in this volume were carefully reviewed and selected from 64 submissions. They focus on advancing the vision of a human-centered society built on a ‘fair pact’ between human being and machines, aiming to create a future where everyone benefits, while ensuring justice, inclusivity, and sustainability for generations to come
Rocking-induced sleep enhancement promotes motor learning through transcriptional and synaptic remodelling
No full text: Growing evidence shows that sleep can be enhanced in a non-invasive, drug-free manner through sensory stimulation. While modalities such as auditory and vestibular stimulation effectively increase sleep, the cognitive and cellular consequences of such enhancement remain unclear. Here, we investigated the effects of vestibular stimulation via rocking on sleep architecture, motor learning, cortical gene expression, and synaptic organization in the motor cortex. Eleven consecutive days of rocking enhanced sleep in mice, increasing both sleep duration and consolidation. These improvements were accompanied by greater motor learning performance, and the degree of learning enhancement positively correlated with total sleep amount. At the molecular level, improved learning was associated with transcriptional changes in genes involved in glutamatergic signalling and synaptic plasticity, alongside an increased density of excitatory synapses in the motor cortex. Together, these findings demonstrate that sleep enhancement via rocking facilitates learning by promoting neuroplastic mechanisms in the motor cortex
Fossil sardines from the Pisco Formation (Miocene), Peru: Taxonomy, taphonomy, and paleoecology
No full textThe Miocene sedimentary sequences of the Pisco Formation (Eastern Pisco Basin, southern Peru) are renowned for the abundance of fossil vertebrates that document the early evolution of the biotic communities of the Humboldt Current Ecosystem. Vertebrate remains are often exceptionally preserved, representing a variety of fishes, turtles, crocodiles, birds, and marine mammals. Here, we describe a new species of sardine, Sardinops humboldti n. sp., based on partially complete articulated skeletons from the Upper Miocene P2 sequence of the Pisco Formation.
This new species is morphologically similar to the extant Indian-Pacific species S. sagax from which it differs by having larger parietals, a thick and much elongate supraoccipital crest, anterolateral processes of the sphenotics that protrude obliquely from the skull roof, posterior margins of the supraoccipital and epioccipitals forming
a broad acute angle approaching 90°, and gently rounded ventral margin of the opercle. Taphonomic and paleoecological evidences suggest that S. humboldti n. sp. was probably very abundant in the Eastern Pisco Basin where it formed relatively small schools of large individuals that were uniform in size, representing the trophic
nucleus of the diverse vertebrate communities. Paleobiogeographic implications are also discussed
Harnessing carlina oxide scaffold for the management of vector-borne diseases: synthesis and structure–activity relationship
No full textVector-borne diseases are causes of global health concern and mosquitoes are the primary transmitters of health-threatening pathogens. Botanicals are sources of compounds structurally modifiable into versatile hits for novel plant-based insecticides. Carlina oxide (1) is a natural compound isolated from Carlina acaulis L. (Asteraceae) with promising insecticidal potential, whose industrial production is limited by the absence of a plant supply chain. Herein, a one-step synthesis producing 1 in 81% yield was developed and a structure–activity relationship (SAR) study for the larvicidal activity on Aedes albopictus (Skuse, 1894) and Anopheles stephensi (Liston, 1901) was performed. The most promising analogue (5) displayed an encouraging larvicidal action (LC50 < 6.0 μg mL−1), safety profile on human keratinocytes (IC50 > 100 μg mL−1) and non-target organisms if compared to 1. Untargeted metabolomic analysis on mosquito larvae revealed that 1 and 5 target the carbohydrates and amino acid metabolism
