107187 research outputs found
Sort by
Metaphors and linguistic intimacy in ad populum arguments
No full textBeyond its cognitive and aesthetic value, metaphor also fosters linguistic intimacy, i.e., the feeling of belonging to an intimate community. The paper hypothesizes that linguistic intimacy might be particularly relevant in ad populum arguments, where a sense of belonging to the community endorsing the argument might influence the acceptance of the conclusion. In ad populum arguments, indeed, metaphors might act as a “concealed invitation” to accept and share a conclusion, encouraging effortful interpretation that results in a feeling of shared community. However, not all
ad populum arguments are fallacious: they may reflect reasonable consensus, with the agreement with their conclusion depending on how they are framed. The article presents an empirical study investigating whether conventional and novel emotive metaphors vs. their literal counterparts within ad populum premises increase participants’ acceptance of the argument conclusion. The results showed that especially novel and negative metaphors in the premises make people less prone to evaluate the conclusion of ad populum arguments as logically acceptable, while conventional and positive metaphors in the premises makes them feel intimacy with the group of people supporting the conclusion, more easily leading to agreement with their conclusion
Mechanochemistry: Redefining the Paradigm of Organic Chemistry
No full textAccording to International Union of Pure and Applied Chemistry (IUPAC), mechanochemistry has been recognized as one of the most innovative transformative technologies in the context of green and sustainable organic synthesis. Mechanochemistry offers discrete reactivities compared to their solution-based counterparts by introducing highly concentrated anisotropic environments combined with energy transfer with discrete pulses rather than a continuous thermal flux, producing a methodology with unparalleled efficiency, selectivity and eco-friendliness. Given all the benefits, mechanochemistry has seen vast applications in organic synthesis for C‒C and C‒N bonds. In addition to all, mechanochemistry has been employed for mechano-redox reactions using piezoelectric materials, photomechanochemistry and synthesis of organometallics. This research investigates different aspects of organic chemistry through mechanochemical perspective by unveiling the reactivity of Bertagnini’s salts as aldehyde surrogates for the synthesis of N-heterocycles and reductive aminations under mechanochemical and microwave systems. Additionally, C‒C bond synthesis reactions using mechanochemically treated wool encompassed sustainability with practicality. Moreover, mechanochemical catalysis for borrowing hydrogenation reactions for C‒N bond synthesis and mechanochemical reaction mechanism studies such as kinetic isotope effect (KIE) and Hammett analysis, combinedly verified the importance of mechanochemistry for green organic synthesis
Fostering well-being in Industry 5.0 through managerial behaviours and enabling technologies
No full textIndustry 5.0 represents the latest industrial evolution, building on the foundations of Industry 4.0 while shifting the focus towards humanity, sustainability and resilience. In this paradigm, enabling technologies are redefined as tools that support human well-being first and business productivity second. Despite its growing relevance, the management literature remains fragmented on how specific managerial behaviours and technologies effectively support these new objectives. To address this gap, this research adopts a systematic literature review and thematic analysis to identify and systematise well-being-centred managerial behaviours and enabling technologies that facilitate the transition to Industry 5.0. The results reveal a relationship between managerial behaviours and enabling technological that can promote well-being-oriented innovation. A key contribution of this study is the conceptualisation of a new value-creation sequence: human well-being serves as the primary driver of productivity, ultimately leading to sustainable competitiveness. These findings offer important theoretical and managerial implications, providing an integrated framework that treats technology as a consequence of human-centred design. Finally, the study outlines future research paths to promote the development of a worker-centred industrial system
A degenerate attraction-repulsion chemotaxis system with logistic-type superlinear degradation
No full textLa pesca del corallo nelle acque della Sardegna: economia, regolamentazione e tensioni tra la Corte sabauda e il Regno di Napoli (1759-1773)
No full textTra il 1759 e il 1773, la Casa sabauda incoraggiò la pesca del corallo con l’obiettivo
di sviluppare un settore economico considerato strategico per la Sardegna,
ridurre la presenza dei corallari stranieri e istituire una Compagnia del corallo.
Tuttavia, la scarsa presenza di corallari sardi, la debolezza economica dell’isola,
la limitata disponibilità di capitali interni e gli interessi commerciali del Regno
di Napoli ne limitarono fortemente il successo: la pesca del corallo rimase così
principalmente una fonte di entrate fiscali. A ciò contribuirono anche il contesto
della Guerra dei Sette Anni e il “rovesciamento delle alleanze” avutosi nel 1756,
che imposero alla Casa Sabauda un’estrema cautela nei rapporti diplomatici. La
gestione del settore della pesca del corallo – che attirava uomini, merci e capitali
dall’estero – non fu, dunque, per la Casa sabauda un fatto puramente interno
Between public service and market: Portraying the bifront university in a platformized world
No full textThis paper contributes to the international debate on the changes affecting recruitment and orientation processes toward higher education. Based on qualitative research involving 19 Italian public universities, the study analyses the transformations in communication, recruitment and orientation activities within platformization and increasing institutional competition. Drawing on Bourdieusian conceptual categories, the analysis highlights how platformization and the changes triggered by the COVID-19 pandemic have opened new opportunities, which universities have interpreted and leveraged in diverse ways according to the evolving nature of the Italian university field as a space of material and symbolic differences. The primary outcome of these transformations is the reinforcement and crystallization of preexisting social and territorial inequalities, which is a historical characteristic of the Italian university system
Novel fatty acid amide hydrolase (FAAH) inhibitors: a patent review from 2015 to 2025
No full textIntroduction: Over the past decade, significant efforts have been made to develop and patent selective fatty acid amide hydrolase (FAAH) inhibitors with favorable pharmacokinetic and safety profiles to modulate pain, inflammation and neurological disorders. Recently, attention has shifted toward dual inhibitors that combine FAAH inhibition with other targets, such as COXs, MAGL, and sEH, aiming to improve therapeutic outcomes. This review highlights the most significant patents from the last ten years in this evolving field of research. Areas covered: Patents of selective and nonselective FAAH inhibitors published from 2015 to 2025. Patent searches was conducted on Espacenet, WIPO (World Intellectual Property Organization) and Google Patents databases, while literature search was performed using the Artificial Intelligence (AI) visual tools Connected Papers and Research Rabbit. Expert opinion: The search for novel and clinically relevant FAAH inhibitors starts with newly disclosed chemical entities. However, reducing translation gaps also requires advances in identifying key biomarkers and developing relevant animal models that mimic target diseases. Additionally, disclosing of innovative chemical templates - including those for allosteric modulation of FAAH - and the identification of suitable and innovative multitarget directed ligands will likely establish FAAH inhibitors as a validated therapeutic option for several diseases
A distance-based aggregation method for finding consensus in preference-approvals
No full textThis paper proposes a distance-based aggregation and consensus method for preference-approvals with potential applications in group decision-making, recommendation systems, and social choice theory. Preference-approvals are a type of preference data where individuals provide a list of approved alternatives in addition to a strict ranking. The proposed method aims to synthesise individual preference-approvals into a unified consensus representing the group’s collective view. The consensus is the preference-approval, which minimises the average distance within the whole set of voters. The performance of the proposed method is investigated through a sensitivity analysis on the weighting parameter, two simulation studies, and two real-data applications
La questione della lingua nella Sardegna della Rinascita tra le pagine della rivista «Ichnusa»
No full textL'articolo ricostruisce il dibattito sulla questione della lingua sarda nella Sardegna degli anni '50-'60, attraverso le pagine della rivista culturale «Ichnusa».The article reconstructs the debate surrounding the Sardinian language question in 1950s-60s Sardinia, through the pages of the cultural journal «Ichnusa»