60419 research outputs found
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Towards a Practical Approach for TE Education: A Pilot Study at the University of Bath
No full textRecent decades have seen increased interest in transdisciplinary (TD) research. To deliver on the promise of TD working there has been a call for the expansion of TD education in emerging literature. The challenge with proposed approaches is that they are often difficult to implement requiring significantly changed courses structures, and the coordination of teams of academic and industry experts to deliver. This creates a barrier to the main-streaming of TD education. Our research aims to create a practical approach for Transdisciplinary Engineering (TE) education which can be easily incorporated within existing course designs and in doing so facilitate wider disseminated. This paper presents the design and pilot of a TE session with MRes students from the University of Bath’s, Centre of Doctoral Training in Advanced Automotive Propulsion Systems. The session is evaluated by way of student feedback. The results show broad satisfaction with the session. Six of the eight indicated that they were satisfied with the quality of the session (two students were neutral). All students considered that the course material was presented in a clear and understandable way. All students considered that the course was accessible to their level of understanding. Future work will see the session delivered within additional engineering MSc courses at Bath and internationally with informal agreements in place with Universities in Colombia, Korea and Poland
Classifying the Disciplinarity of Engineering Academic Literature
No full textBased on the appearance of the term within the academic literature, it would appear that transdisciplinarity (TD) approaches are receiving increased research attention. However, the literature suggests a lack of consensus over how TD is defined and classified. This could give rise to inconsistency and papers that claim to be TD which are not, and alternatively papers that fail to mention TD but which might be classified as such. This is significant and creates a challenge in identifying the true level of TD research. This work contributes towards understanding the state of TD within engineering. Explicitly, we address the research question: Is the engineering academic literature claiming to be TD, actually TD? Within this study we operationalise the work of Jantsch and use this as a means to classify the disciplinarity of 177 engineering journal papers which reference TD within their abstract. The results show only 24% to be TD. The majority (64%) are classified as interdisciplinary. Conclusions find that to improve consistency, a clear definition and rules for differentiation between TD and ID research are required. Future work calls for: (1) comparative studies which apply different methods for assessing disciplinarity across the dataset used within this study and which use the method employed within this study across different fields. (2) Research to analyse whether TD working is being undertaken in engineering without it being referenced within the paper
Colloidal Assembly of Polydisperse Particle Blends during drying
No full textIn this work, we synthesize a polydisperse aqueous colloidal system composed of small and large zwitterionic particles, as well as medium sized standard acrylic particles. By assembling these dispersions into films by drying, we show using atomic force microscopy (AFM) how their top surfaces can be mostly covered by zwitterionic groups for a wide range of evaporation rates. We probe underneath the top film surface using Fourier-transform infrared (FTIR) spectroscopy - attenuated total reflection (ATR), observing that the content in zwitterionic particles of the film upper layer increases for faster evaporation rates. We show how polydisperse systems hold great potential to overcome the evaporation rate dependence of size segregation processes in drying colloidal blends, and we provide further insights into the assembly mechanisms involved. Polydisperse blends enhance the robustness of such processes for application in coatings and other soft products where evaporation rate can not be tuned
The Biochemical Literacy Framework: Inviting pedagogical innovation in higher education
No full textWhen developing meaningful curricula, institutions must engage with the desired disciplinary attributes of their graduates. Successfully employed in several areas, including psychology and chemistry, disciplinary literacies provide structure for the development of core competencies‐pursuing progressive education. To this end, we have sought to develop a comprehensive blueprint of a graduate biochemist, providing detailed insight into the development of skills in the context of disciplinary knowledge. The Biochemical Literacy Framework (BCLF) aspires to encourage innovative course design in both the biochemical field and beyond through stimulating discussion among individuals developing undergraduate biochemistry degree courses based on pedagogical best practice. Here, we examine the concept of biochemical literacy aiming to start answering the question: What must individuals do and know to approach and transform ideas in the context of the biochemical sciences? The BCLF began with the guidance published by relevant learned societies – including the Royal Society of Biology, the Biochemical Society, the American Society for Biochemistry and Molecular Biology and the Quality Assurance Agency, before considering relevant pedagogical literature. We propose that biochemical literacy is comprised of seven key skills: critical thinking, self‐management, communication, information literacy, visual literacy, practical skills and content knowledge. Together, these form a dynamic, highly interconnected and interrelated meta‐literacy supporting the use of evidence‐based, robust learning techniques. The BCLF is intended to form the foundation for discussion between colleagues, in addition to forming the groundwork for both pragmatic and exploratory future studies into facilitating and further defining biochemical literacy
Shell structure of S43 and collapse of the N=28 shell closure
No full textThe single-particle structure of the N = 27 isotones provides insights into the shell evolution of neutron-rich nuclei from the doubly-magic 48Ca toward the drip line. 43S was studied employing the one-neutron knockout reaction from a radioactive 44S beam. Using a combination of prompt and delayed γ-ray spectroscopy the level structure of 43S was clarified. Momentum distributions were analyzed and allowed for spin and parity assignments. The deduced spectroscopic factors show that the 44S ground-state configuration has a strong intruder component. The results were confronted with shell model calculations using two effective interactions. General agreement was found between the calculations, but strong population of states originating from the removal of neutrons from the 2p3/2 orbital in the experiment indicates that the breakdown of the N = 28 magic number is more rapid than the theoretical calculations suggest
Machine learning the deuteron
No full textWe use machine learning techniques to solve the nuclear two-body bound state problem, the deuteron. We use a minimal one-layer, feed-forward neural network to represent the deuteron S- and D-state wavefunction in momentum space, and solve the problem variationally using ready-made machine learning tools. We benchmark our results with exact diagonalisation solutions. We find that a network with 6 hidden nodes (or 24 parameters) can provide a faithful representation of the ground state wavefunction, with a binding energy that is within 0.1% of exact results. This exploratory proof-of principle simulation may provide insight for future potential solutions of the nuclear many-body problem using variational artificial neural network techniques
ICI‐RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?
No full textIntroduction
The following is a report on the proceedings of the 2019 International Consultation on Incontinence‐Research Society nocturia think tank (NTT).
Objectives
The objectives of the 2019 NTT were as follows: (a) to evaluate the role of urothelium in the pathophysiology of nocturia; (b) to determine whether nocturia is a circadian disorder; (c) to discuss the role of melatonin in nocturia; (d) to consider ambulatory urodynamic monitoring in evaluating patients with nocturia; (e) to explore studies of water handling in human compartments utilizing heavy water; and (f) to explore whether basic science is the key to understanding the treatment options for diminished bladder capacity in patients with nocturia.
Methods
A compendium of discussions of the role of experimental science in understanding the pathophysiology of nocturia is described herein.
Results and Conclusions
Translational science will play an increasing role in understanding the pathophysiology of nocturia, which may result in improved treatment strategies.</p
Materialism and the Experience of Flow
No full textThe need to locate ways of living that can be both beneficial to personal well-being and ecologically sustainable is becoming increasingly important. Flow experiences show promise for the achievement of personal and ecological well-being. However, it is not yet understood how the materialistic values promoted by our consumer cultures may impact our ability to experience flow. A cross-sectional survey of 451 people demonstrated that materialistic values and an individual’s tendency to experience flow were negatively correlated (Study 1). Next we showed that experimentally priming a materialistic mind-set led to poorer quality flow experiences in a sample of students (Study 2) and British adults (Study 3). Our findings add to current understandings of the detrimental consequences of materialistic values and suggest that it is crucial to challenge the materialistic values present within our consumer societies if we are to provide opportunities for experiencing flow
Contrasting patterns of isotype-1 β-tubulin allelic diversity in Haemonchus contortus and Haemonchus placei in the southern USA are consistent with a model of localised emergence of benzimidazole resistance
No full textThe benzimidazoles are one of the most important broad-spectrum anthelmintic drug classes for parasitic nematode control in domestic animals and humans. They have been widely used in livestock, particularly in small ruminants for over 40 years. This has resulted in widespread resistance in small ruminant gastrointestinal nematode parasite species, especially Haemonchus contortus. Benzimidazole resistance mutations have also been reported in Haemonchus placei, but only at low frequencies, suggesting resistance is at a much earlier stage of emergence than is the case for H. contortus. Here, we investigate the haplotype diversity of isotype-1 β-tubulin benzimidazole resistance mutations and the population genetic structure of H. contortus and H. placei populations from sheep and cattle from the southern USA. Microsatellite genotyping revealed a low level of genetic differentiation in six H.placei and seven H. contortus populations examined. This is consistent with several previous studies from other regions, mainly in H. contortus, supporting a model of high gene flow between parasite populations. There was a single F200Y(TAC) haplotype present in all six H. placei populations across Georgia, Florida and Arkansas. In contrast, there were at least two different F200Y(TAC) haplotypes (up to four) and two different F167Y(TAC) haplotypes across the seven H. contortus populations studied. These results provide further evidence to support a model for benzimidazole resistance in Haemonchus spp, in which resistance mutations arise from a single, or the small number of locations, in a region during the early phases of emergence, and subsequently spread due to animal movement
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