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    23852 research outputs found

    Defining an Ageing-Related Pathology, Disease or Syndrome: International Consensus Statement

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    Around the world, individuals are living longer, but an increased average lifespan does not always equate to an increased health span. With advancing age, the increased prevalence of ageing-related diseases can have a significant impact on health status, functional capacity and quality of life. It is therefore vital to develop comprehensive classification and staging systems for ageing-related pathologies, diseases and syndromes. This will allow societies to better identify, quantify, understand and meet the healthcare, workforce, well-being and socioeconomic needs of ageing populations, whilst supporting the development and utilisation of interventions to prevent or to slow, halt or reverse the progression of ageing-related pathologies. The foundation for developing such classification and staging systems is to define the scope of what constitutes an ageing-related pathology, disease or syndrome. To this end, a consensus meeting was hosted by the International Consortium to Classify Ageing-Related Pathologies (ICCARP), on February 19, 2024, in Cardiff, UK, and was attended by 150 recognised experts. Discussions and voting were centred on provisional criteria that had been distributed prior to the meeting. The participants debated and voted on these. Each criterion required a consensus agreement of ≥ 70% for approval. The accepted criteria for an ageing-related pathology, disease or syndrome were (1) develops and/or progresses with increasing chronological age; (2) should be associated with, or contribute to, functional decline or an increased susceptibility to functional decline and (3) evidenced by studies in humans. Criteria for an ageing-related pathology, disease or syndrome have been agreed by an international consortium of subject experts. These criteria will now be used by the ICCARP for the classification and ultimately staging of ageing-related pathologies, diseases and syndromes.Output Status: Forthcoming/Available Onlin

    What helps or hinders nurses to lead funded research projects? A survey of UK nurse lead‐investigators

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    Background There have been recurring UK initiatives to increase nurse research capability but little robust evaluation of long-term effectiveness. More nurses undertake doctorates, yet few lead major funded projects. Previous research suggests potential explanations but the perspectives of nurse lead-investigators themselves have not been examined. Aim To explore the perceptions of nurse lead-investigators about what has helped or hindered them to lead funded research projects. Methods Lead investigators of research projects from major UK funders (1 Apr 2017–Sept 2022) were identified from publicly available data. University profiles were screened to identify registered nurses. Entire population was approached (no sample size calculation required). Consenting participants completed an online survey (five open questions). Results A total of 65 nurse-lead investigators were identified, 36 (55%) completed the survey (20 December 2022 to 17 February 2023). Participants identified Building (multi-disciplinary) collaborations and mentorship as having been most important to their success. High-quality mentoring was also identified as most important in helping novice nurse researchers become leaders. Participants highlighted the critical importance of being supported by individuals with a track record of funding success and benefits of being situated in research-supportive environments. Lack of career pathway/infrastructure and being unable to pursue research due to competing clinical/teaching priorities were identified as most unhelpful to this group AND the most common reasons for peers not going on to lead research. Conclusions Ensuring access to mentors with an established track record is an important component of schemes to increase research capability in nurses. Funded, protected time for research and career structures that reward the significant skill development required to succeed in a competitive, multi-disciplinary funding arena is important. Impact Interdisciplinary collaboration and mentorship by experienced researchers are critical to success and should be incorporated into future interventions to increase research capability in nurses. No patient or public contribution (as exploring a professional issue)

    Military Sports Recovery Athletes’ Perspectives on Role of the Coach in Athletes’ Well-Being: The Importance of Supporting Basic Psychological Needs

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    The purpose of this study was to investigate the experiences of athletes in a competitive military sports recovery program with a specific focus on the extent to which coaches supported, or frustrated, athletes’ basic psychological needs. Eight military veteran athletes competing in parasport took part in semi-structured interviews. The accounts of their experiences of working with coaches in this context and their influence on their psychological needs and well-being were thematically analyzed. Results demonstrated that coaches’ behaviors that support basic psychological needs can have positive effects on athletes’ well-being and support their wider rehabilitation. Furthermore, frustration of these needs through controlling behaviors contributed to psychological ill-being. Findings suggest practical implications to help inform coaching practice to support optimal recovery and an environment that promotes well-being.Output Status: Forthcoming/Available Onlin

    Antenatal care of women who use opioids: a qualitative study of practitioners’ perceptions of strengths and challenges of current service provision in Scotland

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    Abstract Background The increasing rise of women using opioids during pregnancy across the world has warranted concern over the access and quality of antenatal care received by this group. Scotland has particularly high levels of opioid use, and correspondingly, pregnancies involving women who use opioids. The purpose of this study was to investigate the different models of antenatal care for women using opioids during pregnancy in three Scottish Health Board Areas, and to explore multi-disciplinary practitioners’ perceptions of the strengths and challenges of working with women who use opioids through these specialist services. Methods Thirteen semi-structured interviews were conducted with health and social care workers who had experience of providing antenatal and postnatal care to women who use drugs across three Scottish Health Board Areas: NHS Greater Glasgow and Clyde, NHS Lothian, and NHS Tayside. Framework Analysis was used to analyse interview data. The five stages of framework analysis were undertaken: familiarisation, identifying the thematic framework, indexing, charting, and mapping and interpretation. Results Each area had a specialist antenatal pathway for women who used substances. Pathways varied, with some consisting of specialist midwives, and others comprising a multidisciplinary team (e.g. midwife, mental health nurse, social workers, and an obstetrician). Referral criteria for the specialist service differed between health board areas. These specialised pathways presented several key strengths: continuity of care with one midwife and a strong patient-practitioner relationship; increased number of appointments, support and scans; and highly specialised healthcare professionals with experience of working with substance use. In spite of this, there were a number of limitations to these pathways: a lack of additional psychological support for the mother; some staff not having the skills to engage with the complexity of patients who use substances; and problems with patient engagement. Conclusions Across the three areas, there appears to be high-quality multi-disciplinary antenatal services for women who use opioids during pregnancy. However, referral criteria vary and some services appear more comprehensive than others. Further research is needed into the perceptions of women who use opioids on facilitators and barriers to antenatal care, and provision in rural regions of Scotland

    ‘If James Bond ever drove a car share, then we have made it’: an exploratory study of institutional work and emotions for mobility as a service in Great Britain and Germany

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    Amidst our climate crisis, transitioning to sustainable practices is imperative. Car dependency turned passenger transport into a major carbon emitter, yet progress to mitigate its impact and change the institutional status quo remains sluggish. Despite increasing awareness and emerging sustainable alternatives, prevailing beliefs in car ownership as synonymous with freedom and emotional attachments to cars challenge a transition. This study generates insights into the ways in which actors perform institutional work to influence institutional change. To investigate strategic efforts of creating and disrupting institutions, it examines Mobility as a Service (MaaS) as one pathway for advancing sustainability and analyses 52 semi-structured interviews with British and German MaaS stakeholders. Based on emerging findings, the study presents a focus on the role of emotions in how actors perform institutional work. The study expands our knowledge of institutional work by further uncovering the role of emotions for institutional change and sustainability transitions. “Emotionalizing Institutional Work” (EIW) is proposed as a new framework, including four analytically distinct strategies: promotive, protective, offensive, and connective emotionalizing. It suggests how actors use emotions as tools in promoting institutional change. Additional findings point to little difference in efforts between Great Britain and Germany, defying expectations rooted in varieties of capitalism. The study contributes to institutional theory with empirical evidence from a complex context. The results help to integrate emotions further into the analysis of institutional work, institutional logics, and chart the underexplored relationship between emotions (as tools) and institutional theory in institutional change processes. Practically, the study enriches transport discourse by presenting emotions as potential push and pull devices for advancing sustainable transport. Ultimately, anyone seeking to influence institutional change and move passenger transport to a reality wherein equitable and sustainable transport is enjoyed by all, will benefit from aiming not only at people’s minds, but their hearts

    Identifying drivers of non-stationary climate-growth relationships of European beech

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    The future performance of the widely abundant European beech (Fagus sylvatica L.) across its ecological amplitude is uncertain. Although beech is considered drought-sensitive and thus negatively affected by drought events, scientific evidence indicating increasing drought vulnerability under climate change on a cross-regional scale remains elusive. While evaluating changes in climate sensitivity of secondary growth offers a promising avenue, studies from productive, closed-canopy forests suffer from knowledge gaps, especially regarding the natural variability of climate sensitivity and how it relates to radial growth as an indicator of tree vitality. Since beech is sensitive to drought, we in this study use a drought index as a climate variable to account for the combined effects of temperature and water availability and explore how the drought sensitivity of secondary growth varies temporally in dependence on growth variability, growth trends, and climatic water availability across the species’ ecological amplitude. Our results show that drought sensitivity is highly variable and non-stationary, though consis- tently higher at dry sites compared to moist sites. Increasing drought sensitivity can largely be explained by increasing climatic aridity, especially as it is exacerbated by climate change and trees’ rank progression within forest communities, as (co-)dominant trees are more sensitive to extra-canopy climatic conditions than trees embedded in understories. However, during the driest periods of the 20th century, growth showed clear signs of being decoupled from climate. This may indicate fundamental changes in system behavior and be early-warning signals of decreasing drought tolerance. The multiple significant interaction terms in our model elucidate the complexity of European beech’s drought sensitivity, which needs to be taken into consideration when assessing this species’ response to climate change.Additional authors: Isabel Dorado-Liñán, Choimaa Dulamsuren, Balázs Garamszegi, Michael Grabner, Andrew Hacket-Pain, Jon Kehlet Hansen s, Claudia Hartl, Weiwei Huang, Pavel Janda, Marko Kazimirović, Florian Knutzen, Jürgen Kreyling, Alexander Land, Nicolas Latte, François Lebourgeois, Christoph Leuschner, Luis A. Longares, Edurne Martinez del Castillo, Annette Menzel, Renzo Motta, Lena Muffler-Weigel, Paola Nola, Momchil Panayatov, Any Mary Petritan, Ion Catalin Petritan, Ionel Popa, Cǎtǎlin-Constantin Roibu , Álvaro Rubio-Cuadrado, Miloš Rydval, Tobias Scharnweber, J. Julio Camarero, Miroslav Svoboda, Elvin Toromani, Volodymyr Trotsiuk, Marieke van der Maaten-Theunissen, Ernst van der Maaten, Robert Weigel, Martin Wilmking, Tzvetan Zlatanov, Anja Rammig, Christian S. Zan

    Bi-Lipschitz embeddings of the space of unordered m-tuples with a partial transportation metric

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    see publishers website for abstract doi.org/10.1007/s00208-024-02831-

    The Incidence and Persistence of Partnerships in a British Industrial City: Glasgow, 1861-1881.

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    This paper examines the prevalence of business partnerships in a late nineteenth century British city, using individual level data from Post Office directories and censuses. Focusing on Glasgow, we present a detailed picture of partnership number and type, demographic characteristics of the entrepreneurs who ran them, and how these businesses persisted over time. We show that partnerships were a key business grouping in the city, demonstrate that the partnership form was advantageous in manufacturing, and that the majority of partnerships were formed between individuals without family ties. Furthermore, we offer new insight into business longevity, showing that partnership business survival broadly matched corporate survival rates in this period, with persistence data also suggesting that kinship partnerships were better able to deal with the perceived hold-up problems associated with the partnership form

    Representing Scotland: Conservative Narratives of Nation, Union, and Scottish Independence

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    The United Kingdom’s vote to exit the European Union reignited the debate about Scottish independence, requiring statewide political parties to rearticulate the case for the Union. The UK Conservative Party, as the party of government and one with a tumultuous history vis-à-vis Scotland and devolution, was at the fore in making this case. This article explores representations of Scotland, its position within the United Kingdom, and Scottish nationalism as a political force by the Conservative Party at a prolonged moment of significant political and constitutional tension. We focus, therefore, on 2019 to 2024, a parliamentary term and political period defined by protracted debates on Scotland’s place within the Union, playing out against the backdrop of the Brexit negotiations, the Covid-19 pandemic, and a worsening cost-of-living crisis. To this end, we draw upon parliamentary debates, two daily English newspapers (The Daily Telegraph and the Sun) and two online right-leaning news sites (ConservativeHome and The Spectator online). Our analysis identifies three distinct but interrelated strands in Conservative representations of Scotland, each of which is centred on a contrast. First, a distinction between an inclusive unionism versus a narrow nationalism; second, a largely economic narrative, contrasting a prosperous union with the economic risks of independence; and finally, a contrast between governmental competence at Westminster and the SNP-led Scottish Government failing Scotland. These contrasting narratives elucidate the ways in which Conservatives construct representations of Scotland, particularly at moments of constitutional contestation

    Tobacco, e-cigarette and alcohol content in popular UK soap operas: a content analysis to explore changes in social norms and scene location

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    Background: Exposure to tobacco and alcohol on-screen promotes use and despite regulations and policies to limit impact, these behaviours remain common. We report a longitudinal analysis of tobacco, e-cigarette and alcohol content in three popular UK television soap operas, to examine changing social norms between 2002 and 2022. Methods: We used one-minute interval coding to measure content in programmes in two one-week periods in three years (2002, 2012 and 2022). Change in the probability of actual and implied use of tobacco, e-cigarette and alcohol over time was examined using logistic regression. Results: We coded 2505 intervals from 78 episodes. Tobacco content occurred in 22% of episodes and significantly decreased from 2002 to 2022 (OR 0.15 95% CI 0.06–0.40). Tobacco use changed over time with decreasing use indoors and increasing use outdoors. No e-cigarette use was identified. Alcohol content was found in 88% of episodes and while it also significantly decreased over time (OR 0.78 95% CI 0.61–0.99) it featured in 20% of broadcast minutes in 2022. Alcohol use in homes increased over time. Conclusion: While tobacco imagery is increasingly rare in these three UK soap operas, alcohol content has remained common. Tightening the UK Ofcom regulations would help to reduce young people’s exposure to these harmful behaviours and their potential influence on social norms now and in the future

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