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Deep learning based residential load identification model and performance analysis
No full textIn light of the rapidly evolving energy demands of the modern era, it is becoming increasingly clear that home energy management is more crucial than ever. With the advent of smart home technologies, the effective identification and management of loads is becoming a crucial area of focus. In this paper, we present a novel CNN deep learning-based method for residential load identification. We evaluate the effectiveness and applicability of the proposed model by comparing it with traditional machine learning methods such as Random Forest, Decision Trees and K-Nearest Neighbor. The results of the study, which were supported by experimental data from Afyon Kocatepe University laboratories, indicate that the CNN deep learning model may offer the most promising performance in critical metrics such as accuracy, precision, sensitivity and Fmeasure
ODNOS IZME?U ERGOSTEROLA I Alternaria MIKOTOKSINA U PARADAJZU SA RAZLI?ITIM POVRŠINSKIM PROPORCIJAMA
No full textThis study evaluates the relationship between ergosterol (ERG) and Alternaria mycotoxins (AOH, AME, TenA) concentrations in tomato samples with varying decay levels. Using Rio Grande tomatoes, decay levels ranged from 89% to 99%. Samples were categorized based on visible mold, processed into pulp, and evaluated for quality parameters such as soluble solids, pH, acidity, and color. HPLC determined ERG, TenA, AOH, and AME levels, providing data on standard curve linearity, detection limit, recovery, and precision. Correlations between decay proportions and toxin concentrations were analyzed to understand variable relationships and quality implications for the tomato industry. Results indicate significant (p<0.05) effects of decay levels on toxin concentrations, emphasizing the importance of these measures for tomato quality assessment. The strong correlations among parameters underscore their relevance for quality control in tomato processing. This study contributes valuable insights for future research in this domain.Honaz Tomato Paste FactoryThe authors would like to acknowledge the Honaz Tomato Paste Factory, for funding this research and providing the samples
Identification of yeast in healthy and subclinical mastitis-diagnosed Anatolian buffaloes in smallholder dairy farms in Turkey
Get PDFThis study aimed to identify yeast species in healthy Anatolian buffaloes and those with subclinical mastitis on smallholder farms using the Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF MS) method and assess antifungal resistance. Milk samples from 390 udder lobes of 100 buffaloes were tested and California Mastitis Test (CMT) results showed 265 negative, 102 suspicious and 23 CMT >=+1 lobes. A total of 76 yeast isolates (19.5%) were obtained through classical culture methods. MALDI-TOF MS identified seven genera, with the most common species being Pichia kudriavzevii (54%), Kluyveromyces marxianus (21%) and Nakaseomyces glabrata (10.5%). Antifungal resistance was determined by the disk diffusion method, showing the highest resistance to caspofungin (69.7%), followed by fluconazole (65.8%) and ketoconazole (31.6%). This study highlights the presence of diverse yeast species in buffalo milk, emphasizing the importance of understanding their role in mastitis and antifungal resistance for animal and public health. To our knowledge, this is the first study showing the identification of different yeast species isolated from Anatolian buffaloes in smallholder dairy farms in Turkey
The impact of laser cutting and engraving technologies on creative and technical processes in design-based education
No full textBu çalışma, tasarım odaklı eğitim alanlarında lazer kesme ve kazıma teknolojilerinin yaratıcı ve teknik süreçler üzerindeki kullanımını ele almaktadır. Teknolojik gelişmelerle birlikte tasarım süreci dijital ortama taşınmış; üç boyutlu modelleme ve sanal üretim araçları eğitimde daha sık kullanılmaya başlanmıştır. Ancak fiziksel üretim ve materyalle çalışma deneyimi, hâlâ önemli bir öğrenme aracı olmayı sürdürmektedir. Lazer kesme ve kazıma makineleri, öğrencilerin yaratıcı düşünme becerilerini geliştirmelerine ve teknik uygulamalara daha kolay erişmelerine katkı sağlayan araçlar arasında yer almaktadır. Bu bağlamda çalışmada, söz konusu makinelerin eğitim sürecindeki yeri, kullanıcı deneyimleri, sağladığı imkânlar ve karşılaşılan bazı zorluklar genel hatlarıyla incelenmiştir. Ayrıca lazer kesme ve kazıma teknolojilerinin sunduğu çeşitli olanaklar ve sınırlılıklar değerlendirilerek, bu araçların tasarım temelli eğitimdeki rolü üzerine bir perspektif sunulmuştur.This study explores the use of laser cutting and engraving technologies in design-oriented educational contexts, focusing on their role in creative and technical processes. With technological advancements, the design process has increasingly shifted into digital environments, and tools such as 3D modeling and virtual production have become more common in educational settings. However, physical production and hands-on material experience still remain important components of learning. Laser cutting and engraving machines are among the tools that support students in developing creative thinking skills and gaining easier access to technical applications. In this context, the study examines the role of these machines in the educational process, user experiences, the opportunities they offer, and some of the challenges encountered. Furthermore, the study provides an overview of the advantages and limitations of laser technologies and reflects on their place in design-based education
Effect of propolis supplementation on haematological and biochemical parameters in lambs
No full textThis study evaluated the effects of oral propolis supplementation on haematological and metabolic indicators and coagulation parameters in neonatal lambs. Forty healthy newborn lambs were randomly assigned to either a control group or a treatment group receiving 1.5 mL of propolis extract daily for 15 days. Blood samples were collected on days 0, 7, 21, and 45 to assess for changes over time. The results showed that propolis did not cause any harmful effects on liver or kidney function, and all blood parameters remained within normal physiological ranges. Although most changes in biochemical markers were time-related, lambs supplemented with propolis showed slight improvements in lipid metabolism, including numerically lower cholesterol and triglyceride levels at specific time points. Moreover, lambs in the propolis group tended to gain more weight over time, suggesting possible benefits for early growth. Minor differences were observed in some clotting parameters, but no adverse effects on blood coagulation were detected. These preliminary findings suggest that propolis may be considered a complementary strategy in lamb production, although further studies are needed to confirm its long-term benefits. Propolis-use may help facilitate a reduction in the use of synthetic additives in small ruminant production systems.Afyon Kocatepe University Scientific Research Projects Unit [SAG.BIL.07]Acknowledgements This research was funded by the Afyon Kocatepe University Scientific Research Projects Unit (20. SAG.BIL.07)
Enhanced thermal, dielectric, and antimicrobial performance of fluorinated methacrylate and chitosan-based nanocomposites reinforced with TiO2 nanowires
No full textIn this study, we developed multifunctional nanocomposite structures by hydrothermally incorporating 3%, 5%, and 7% titanium dioxide nanowires (TiO2 NWs) into a PTFBMA-CS matrix. This matrix was formed by blending PTFBMA polymer derived from 4-trifluoromethylbenzyl methacrylate (TFBMA) monomer with chitosan (CS). Our innovative system demonstrated significant performance improvements in dielectric, thermal, and antimicrobial properties, demonstrating the potential of these structures for various applications. Structural characterizations were performed using FTIR, XRD, SEM-EDX, and TEM techniques, and the TiO2 NWs were observed to be homogeneously dispersed, retain their anatase phase, and interact strongly with the polymer matrix. Thermal analyses (TGA/DSC) showed that the initial decomposition temperature increased from 314 to 334 degrees C at 7% additive content, and the glass transition temperature (Tg) value increased by approximately 13 degrees C. This is consistent with findings from the literature that metal oxide additives increase heat resistance by stabilizing the amorphous structure. In antimicrobial tests, inhibition zones larger than 10 mm were obtained on E. coli, S. aureus, and C. albicans in the 7% additive sample, confirming the contribution of TiO2 nanoparticles to antimicrobial activity. Dielectric measurements showed that the epsilon ' value increased significantly with increasing additive content, reaching a value of 7.4 at a frequency of 1000 Hz, particularly in the 7% additive sample. This increase is attributed to dipole-dipole interactions generated by the nanostructures and interfacial polarization. Additionally, contact angle measurements revealed that the surface became more hydrophilic (decreased from 64.04 degrees to 50.99 degrees) and the surface free energy increased to 52.97 mN/m. This demonstrates the material's suitability for biomedical coating and sensor surface applications. In conclusion, these nanocomposite systems, developed through the synergistic effects of organic (PTFBMA and CS) and inorganic (TiO2 NW) components, are groundbreaking. The obtained data suggest that the produced nanocomposites can be used in biomedical coatings, dielectric systems, antimicrobial films, and sensor technologies. These structures are considered particularly important in flexible electronics and sustainable biomaterials, generating excitement and anticipation for their future potential.Afyon Kocatepe University Scientific Research Projects [24. FENED.06]This study has been supported by the Afyon Kocatepe University Scientific Research Projects Coordination Unit. The Project Number is 24. FENED.06
Ruminantlarda Rumenin Önemi
Get PDFÇalışmada ruminantların rumenlerinin bu hayvanlar için ne kadar önemli olduğunu ortaya koymak amaçlanmıştır. Ruminantlardan elde edilen süt ve et insanların beslenme kaynakları açısından oldukça önemlidir. Ruminantların ön midelerinden olan rumen ruminantlar için çok önemlidir. Fakat ruminantların doğduklarında rumenleri faaliyet gösterememektedir. Rumen içerisindeki mikroorganizmalar ile birlikte ruminantlar selüloz gibi maddeleri sindirebilirler. Rumen mikroorganizmaları tüm gıdaların sindirim faaliyetleri neticesinde ruminantların büyük ölçüde enerji ihtiyacını sağlayan Uçucu Yağ Asitlerine (UYA) dönüşürler. Ayrıca azot kaynakları da rumen mikroorganizmalarının faaliyetleri sonrasında mikrobiyel proteinlere dönüştürülmektedir. Rumen mikroorganizmaları B grubu vitaminleri de sentezleyerek ruminantların faydalanmasını sağlamaktadır. Rumen mikroorganizmaların yasayabilmeleri için rumenin içerisinin dengede kalması gerekir. Rumenin içerisinin sıcaklık, besin, pH gibi değerliliklerinin standart aralıklarda tutulmalıdır. Rasyonlarda bulunan yemlere ek olarak rasyona canlı mikroorganizmalar ve aromatik yağlar gibi katkı maddeleri eklemek rumen standartlarını sağlamaya yardımcı olur. Rumen içerisine yerleştirilen sensörlerle rumenin pH, sıcaklık gibi değerlerin anlık ölçümleri yapılabilmektedir. Böylece hayvanlar sürekli gözlem altında tutularak daha sağlıklı ve verimli yetiştirilmektedir
Development of Mesoporous Silica Nano-Shells for Controlled Release of Doxorubicin
Get PDFPorous and spherical silica nano-shells (PSNSs) have garnered significant attention due to their potential applications in drug delivery systems, water treatments, etc. This study produced and characterized seven different PSNSs (S-1,2,3,4,5,6,7) using new methods. The selected products' (S-4 and S-7) surface areas were determined to be 702.2 m2/g and 452.2 m2/g, respectively. Pore size distributions were found as in the range of 7.3 nm to 10.6 nm. The most notable finding of this study was the attainment of mesoporosity in the synthesis of nano-sized silica (S-7) without the use of surfactant agents like CTAB. Six different doxorubicin (DOX) loaded formulations were prepared using S-4 and S-7 products. The DOX release profiles and kinetics of these formulations were investigated in detail. Drug release studies showed that some PSNSs performed controlled release of DOX lasting approximately 10 h. Several kinetic models were analyzed based on in vitro DOX release data and the results were found to be more consistent with the Higuchi and Korsmeyer-Peppas release kinetic models.Scientific and Technological Research Council of Turkey (TUBIdot;TAK) - Afyon Kocatepe University Scientific Research Project (BAP) [23.FEN.BIL.20]The authors would like to express their gratitude for the support received from the Scientific and Technological Research Council of Turkey (TUB & Idot;TAK) through the 2211-A Domestic Graduate Scholarship Program. This research was financially backed by Afyon Kocatepe University Scientific Research Project (BAP), Project No: 23.FEN.BIL.20
Behavioral, normative, and control determinants of in-class off-task multitasking and its association with perceived learning
No full textThe widespread adoption of mobile technologies has exacerbated their utilization in educational environments. Multitasking in the classroom is a common practice and deserves further investigation to understand its antecedents. Yet, rare studies have addressed this issue based on the theory of planned behavior framework. To this end, the current research focused on the antecedents of in-class off-task multitasking from the lens of the theory of planned behavior and its relation to perceived learning. An integrative, comprehensive model was utilized for this aim. Employing a cross-sectional survey design, the data were collected from 246 university students. The model was assessed using SmartPLS 3.2.7 in partial least square structural equation modeling (PLS-SEM). The research revealed that the theory of planned behavior was a valuable framework for understanding behavioral, normative, and control determinants of in-class off-task multitasking and its relation to perceived learning. Specifically, attitude towards multitasking, prescriptive and descriptive norms, and perceived behavioral control significantly contributed to the prediction of multitasking behavior and perceived learning. Moreover, fear of missing out, attitudes toward using digital devices during lectures, multitasking self-efficacy, and working memory capacity exhibited significant and indirect predictive effects on multitasking. While gender did not impact multitasking in the classroom, the study demonstrated a negative association between age and multitasking. The results are discussed, and implications are provided for educators to address in-class off-task multitasking behavior. The study indicated that university students must acknowledge that multitasking is unachievable without declining performance despite their belief in their ability to multitask successfully. Based on the results, we suggest that students should be informed about the limitations of human cognitive architecture. Some interventions to alter attitudes are also recommended
Protective Effects of SIRT2 Inhibition on Cardiac Fibrosis
Get PDFBackground:A primaryfactor inthe pathogenesis of aging is oxidative stress, with cardiac inflammation and fibrosis being contributed to by increased oxidative stress as organisms age. Oxidative stress enhances the cardiac fibrotic signaling pathway, with reactive oxygen species inducing cardiac fibrosis through increased expression of the profibrotic factor transforming growth factor-beta 1 (TGF-(31). Furthermore, Wnt/(3-catenin signaling pathway is implicated in interstitial fibrosis, which is associated with TGF-(3. Sirtuin (SIRT2) is expressed in heart tissue, with protective effects in pathological cardiac hypertrophy. We aimed to investigate the mechanisms of cardiac fibrosis in D-Galactose (D-Gal)-induced accelerated aging, focusing on TGF-(31, (3-catenin, and SIRT2. Methods: A total of 30 young male Sprague-Dawley rats were randomly divided into 4 groups: control group, D-Gal group, D-Gal + 4% dimethyl sulfoxide (DMSO) group, and-Gal + the SIRT2 inhibitor (AGK2) group. After 10 weeks, the rats were sacrificed, and their hearts were removed. SIRT2 expression levels were measured by western blot and gene expression levels of TGF-(31 and (3-catenin by quantitative real-time polymerase chain reaction. Results: Transforming growthfactor-beta 1 (TGF-(31) mRNA expression in hearttissuewas higher in the D-Gal group compared to all other groups. (3-catenin mRNA expression was higher in the D-Gal group than in the D-Gal +AGK2 group. SIRT2 protein expression was higher in the D-Gal +DMSO group compared to the control group. Sirtuin 2 expression was lower in the D-Gal +AGK2 group compared tothe D-Gal and D-Gal +DMSO groups. Conclusion: Sirtuin 2 inhibition attenuates fibrosis, as evidenced by the downregulation of TGF-(31 and (3-catenin. Thus, targeting SIRT2 may represent a potential therapeutic strategy for diseases characterized by cardiac fibrosis in the future