2671 research outputs found
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Rapid Assessment of Avoidable Blindness Report: Indonesia, North Sumatra (2016)
A report including output of standardised analysis of vision and eye health survey data including tables of vision impairment prevalence and service coverage estimate
Structural and social factors affecting COVID-19 vaccine uptake among healthcare workers and older people in Uganda: A qualitative analysis. Data file
The COVID-19 vaccine rollout programme in Uganda was launched in March 2021 for priority groups: Healthcare Workers (HCWs), older persons (≥50 years), and persons with chronic conditions. Misinformation, distrust in healthcare systems, and cultural beliefs, pose significant challenges to vaccine uptake. We describe the social and structural factors affecting the uptake of COVID-19 vaccines among HCWs and older people in Uganda. Between September and October 2021, we conducted 33 in-depth interviews with 25 HCWs aged 21–63 years from three hospitals in central Uganda and eight older people from Wakiso district. Participant selection was purposive, based on sex, occupation, education, cadre of HCWs and vaccination status. We explored participants’ knowledge, beliefs, personal experiences, barriers, and facilitators to vaccine uptake as well as suggestions for future COVID-19 vaccine rollout. Interviews were audio-recorded, transcribed and translated into English, coded, and analysed by theme. Twenty-two of the 25 (88%) HCWs and 3 of the 8 (38%) older people had received at least one dose of the COVID-19 vaccine at the time of interview. The structural facilitating factors to vaccine uptake included access to correct information, fear of a risky work environment, and mandatory vaccination requirements especially for frontline HCWs. Age, chronic health conditions, and the fear of death were facilitating factors for older people. Misconceptions about COVID-19 vaccines and fear of side effects were common social barriers for both groups. Long distances to vaccination centres, vaccine stock-outs, and long queues at the vaccination centres were specific barriers for older people. The prerequisite of signing a consent form was a specific structural barrier for HCWs. Future roll out of new vaccines should have a comprehensive information dissemination strategy about the vaccines. Improved access to vaccines through community outreach, reliable vaccine supplies and addressing vaccine misinformation, may enhance COVID-19 vaccine uptake
MatthewHiggins2017/PanPlasmodiumRPALFManuscript
A list of NCBI IDs for sequences used in the in-silico analysis outlined in "A Pan Plasmodium lateral flow recombinase polymerase amplification assay for monitoring malaria parasites in vectors and human populations"
Rapid Mortality Mobile Phone Survey, Malawi 2022-2023
The Rapid Mortality Mobile Phone Surveys (RaMMPS) https://www.lshtm.ac.uk/rammps/ project aims to develop and field-test methods and survey instruments for collecting mortality data over the phone. RaMMPS studies are (repeated) cross-sectional surveys. The Malawi RaMMPS was conducted between 24 January 2022 and 28 July 2023
Supplementary material for "Mapping the evidence of novel plant-based foods: A systematic review of nutritional, health, and environmental impacts in high-income countries"
This is a complementary zip file that includes all the supplementary material associated with the following publication: Nájera Espinosa S. et al. Mapping the evidence of novel plant-based foods: a systematic review of nutritional, health, and environmental impacts in high-income countries, Nutrition Reviews, 2024, nuae031, https://doi.org/10.1093/nutrit/nuae031
ehr-lshtm/code-sharing: published_article
Code and data for a review of code sharing and other open science indicators in the journal pharmacoepidemiology and drug safety
Widespread human exposure to ledanteviruses in Uganda: A population study
Le Dantec virus (LDV), assigned to the species Ledantevirus ledantec, genus Ledantevirus, family Rhabdoviridae has been associated with human disease but has gone undetected since the 1970s. We describe the detection of LDV in a human case of undifferentiated fever in Uganda by metagenomic sequencing and demonstrate a serological response using ELISA and pseudotype neutralisation. By screening 997 individuals sampled in 2016, we show frequent exposure to ledanteviruses with 76% of individuals seropositive in Western Uganda, but lower seroprevalence in other areas. Serological cross-reactivity as measured by pseudotype-based neutralisation was confined to ledanteviruses, indicating population seropositivity may represent either exposure to LDV or related ledanteviruses. We also describe the discovery of a closely related ledantevirus in blood from the synanthropic rodent Mastomys erythroleucus. Ledantevirus infection is common in Uganda but is geographically heterogenous. Further surveys of patients presenting with acute fever are required to determine the contribution of these emerging viruses to febrile illness in Uganda
Rapid Assessment of Avoidable Blindness Report: Philippines, Western Visayas, Negros (2005)
A report including output of standardised analysis of vision and eye health survey data including tables of vision impairment prevalence and service coverage estimate
Rapid Assessment of Avoidable Blindness Report: Iran, Tehran, Varamin (2009)
A report including output of standardised analysis of vision and eye health survey data including tables of vision impairment prevalence and service coverage estimate
Rapid Assessment of Avoidable Blindness Report: Burkina Faso, West Central (2011)
A report including output of standardised analysis of vision and eye health survey data including tables of vision impairment prevalence and service coverage estimate