2671 research outputs found
Sort by
emilycfivian/Intersectionality-in-NSA-interventions-Analytical-code
No full textAnalytical code for "Can nutrition-sensitive agriculture interventions address intersectional inequalities in women’s diets? A mediation analysis using cross-sectional trial data from Odisha, India
ManuelaQuaresma/CSI
No full textThe index of cancer survival is a single number indicator that summarises the overall patterns of cancer survival for all cancer types combined. The index does not reflect the prospects of survival for any individual cancer patient (or group of patients). It was developed to act as a strategic tool for national surveillance and local monitoring of the effectiveness of cancer services in a given population. his repository contains the materials (synthetic data and R code) used in the illustration of the above mentioned tutorial, to enable the user to replicate the construction of the index, and to apply it to their own data
Studies of microbial keratitis treatment, prevention and diagnosis in Nepal and East Africa
No full textThe impact of weekly fever-screening and treatment and monthly RDT testing and treatment on the infectious reservoir of malaria in Burkina Faso: results from a cluster-randomised trial
No full textThe majority of malaria infections in endemic countries are asymptomatic and a source of onward transmission to mosquitoes. Malaria transmission and disease burden could be reduced by improving early detection and treatment of these infections with active screening approaches. In an 18-month cluster-randomized study in Sapone, Burkina Faso, households were enrolled and randomised to 1 of 3 arms: arm 1 - control; arm 2 - active weekly screening for febrile individuals and treatment if rapid diagnostic test (RDT) positive; or arm 3 – active weekly fever-screening (as arm 2) plus monthly RDT-testing regardless of symptoms. The primary outcome was parasite prevalence by qPCR in the end-of-study cross-sectional survey. Secondary outcomes included parasite and gametocyte prevalence and density in all three end-of-season cross-sectional surveys, incidence of infection, and the transmissibility of infections to mosquitoes. A total of 906 individuals were enrolled during 2 phases. In Phase 1, 412 individuals were enrolled between August 9 and 17, 2018, and in Phase 2, 494 individuals were enrolled between January 10 and 31, 2019. In the end-of-study cross-sectional survey, malaria parasite prevalence by qPCR was statistically significantly lower in arm 3 (29·26% 79/270), but not in arm 2 (45·66% 121/265), when compared to arm 1 (48·72% 133/273) (RR = 0·65, 95%CI = 0·52 to 0·81, P=0·0001). Total parasite and gametocyte prevalence and density were also significantly lower in arm 3 in all surveys. The largest differences were seen at the end of the dry season, with gametocyte prevalence 78·38 % and transmission potential 98·20% lower in arm 3 vs arm 1. Active monthly RDT testing and treatment can reduce parasite carriage and the infectious reservoir of malaria to <2% when used during the dry season. This insight may inform approaches for malaria control and elimination
Data For: Optimising Instructional Materials for COVID-19 Rapid Tests for Self-Sampling and Testing: Mapping the Optimization Process of Manufacturer’s Instructions for Use for Self-Testing RDTs Intended for Low Literacy Contexts
No full textData collected as part of an observational, cross-sectional study of the feasibility and acceptability of self-sampling and self-testing using SARS-CoV-2 antigen tests in adults in the general population and health care workers. Cognitive interviews were conducted at the Queen Elizabeth Central Hospital (QECH) and Lirangwe in Blantyre, Malawi. Data files shared in this first version of the deposit consist of 58 PANBIO and 62 STDQ interview transcripts. The interviewer questions are typically in English, while the respondents’ answers are given in Chichewa
enilles1/DR-Leptospirosis
No full textQuanitative data and R code produced as part of a multi-stage cluster survey on Seroepidemiology of human leptospirosis in the Dominican Republic. Information on the data collection methodology can be found in accompanying publications
The Capabilities in Academic Policy Engagement (CAPE) programme in England: a mixed methods evaluation
No full textThe Research England funded Capabilities in Academic Engagement (CAPE) study aimed to better understand how best to support effective and sustained engagement between academics and policy professionals across the higher education sector. This item contains the survey question list, academic interview topic guide, and policy interview topic guides used in the research
Supplemental Data for "A validated pangenome-scale metabolic model for the Klebsiella pneumoniae species complex."
No full textThis figshare directory contains supplemental data for the publication "A validated pangenome-scale metabolic model for the Klebsiella pneumoniae species complex"
EpiNow2: Estimate Real-Time Case Counts and Time-Varying Epidemiological Parameters
No full textEstimates the time-varying reproduction number, rate of spread, and doubling time using a range of open-source tools (Abbott et al. (2020), and current best practices (Gostic et al. (2020). It aims to help users avoid some of the limitations of naive implementations in a framework that is informed by community feedback and is actively supported
