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令和6年度札幌市大学と民間企業等との連携による公益的事業の推進補助金 札幌市の劇団他と連携した演劇的手法による地域課題解決に取り組むプロジェクトマネージャー養成事業 実施報告書
No full text北海道大学大学院教育推進機構リカレント教育推進部が2024年度に行った「札幌市の劇団他と連携した演劇的手法による地域課題解決に取り組むプロジェクトマネージャー養成事業」に関する報告書
The Process of The Shift of Student Interest in High School-University Articulation: Based on The Analysans of Narratives of Students Who Entered through Inquiry-Based University Entrance Examinations
No full textThis study aimed to provide a novel perspective on high school-university articulation by examining how students connect the interests they discovered through this inquiry-based learning to their university studies. To this end, a semi-structured interview survey was conducted with three students who had engaged in inquiry-based learning in high school, passed the Inquiry-Based University Entrance Examinations, and subsequently matriculated at a comprehensive research university. The narratives were subjected to a reflexive thematic analysis. The themes included the expansion of interests and concerns through in- and out-of-class, the reconstruction of interests and concerns through communication with diverse academic fields and the transformation of personal interests and concerns. These findings suggest a new approach to high school- university articulation that considers the process of reconstructing the learning of individual students in the regular curriculum as well as in co-curricular and extracurricular activities
Post-translational modification of D1 and its proteolysis in the Photosystem II repair.
No full text光合成を駆動するために光は必要不可欠であるが，光は同時にチラコイド膜上の光化学系II複合体に損傷を与える．光合成生物は損傷した光化学系IIを修復する優れた機構を持っており，損傷を受けた反応中心タンパク質D1を選択的に分解し，新規合成したものと入れ換える．FtsHプロテアーゼは損傷D1タンパク質の分解で主要な役割を果たしており，その機能調節や基質認識メカニズムが解き明かされつつある．ここでは光化学系IIの修復機構を概説するとともに，FtsHの機能調節についての進展と，D1タンパク質で生じるアミノ酸の酸化修飾が損傷D1タンパク質の選別と分解に関わるメカニズムについて述べる．Light energy is essential for driving photosynthesis but also causes oxidative damage to the Photosystem II (PSII) complex. Photosynthetic organisms have developed an efficient PSII repair mechanism to maintain photosynthetic activity. Photo-damaged D1, the primary target of unavoidable photo-oxidative damage, is selectively degraded by proteases and replaced with a newly synthesized D1 protein. FtsH, a thylakoid-bound ATPdependent metalloprotease, plays a crucial role in the specific degradation of photo-damaged D1. Here, we provide an overview of the PSII repair mechanism and highlight recent progress in understanding the functional regulation of FtsH. We also introduce our recent study, which revealed that an oxidative post-translational modification of a Trp residue at the N-terminal tail of D1 is a critical factor in D1 degradation by FtsH
The nonheterocystous filamentous nitrogen fixing cyanobacterium Leptolyngbya boryana : Potential as a new model cyanobacterium
No full textLeptolyngbya boryanaは，糸状性シアノバクテリアであり，ヘテロシストを分化せず，嫌気（微好気）環境において窒素固定的に生育することができる．また，完全暗所においてもグルコースなどの糖を利用して従属栄養的に生育することができることから，光合成生育能を欠いた変異株の単離が可能である．全ゲノム配列が既に解読済みであり，電気穿孔法もしくは接合法により形質転換が可能である．シャトルベクターを利用した大量発現系およびレポーター系が利用でき，トランスポゾン変異導入による順遺伝学的解析も可能である．本稿では，L. boryanaの特徴と研究事例（クロロフィル生合成，窒素固定，細胞外小胞，従属栄養に関する分子生物学的研究）および窒素固定研究の方法を紹介し，今後
の展望について述べる．Leptolyngbya boryana is a filamentous cyanobacterium that can grow diazotrophically without heterocyst differentiation under anaerobic (microoxic) conditions. Since L. boryana can also grow heterotrophically in the dark using respiratory substrates such as glucose, mutants lacking photosynthetic growth capacity can be isolated. The genome has been sequenced, and L. boryana is transformable by electroporation or conjugation. Shuttle vector, reporter, and transposon mutagenesis systems have been established in L. boryana. Using the L. boryana’s
characteristics, molecular biological studies on chlorophyll biosynthesis, nitrogen fixation, extracellular vesicles, and heterotrophy have been conducted. In this paper, the characteristics of L. boryana, research examples and methods of nitrogen fixation studies are presented, and prospects are discussed
投射動作における自己および他者の誤差に基づく試行間学習 [全文の要約]
No full textこの博士論文全文の閲覧方法については、以下のサイトをご参照ください。https://www.lib.hokudai.ac.jp/dissertations/copy-guides