81690 research outputs found
Sort by
Door's computational(Shushu 数術) significances in unearthed Ri Shu's divination
No full text数術文献である出土『日書』には実在の居室の門や、孤虚術において気が出入する門、刑徳六舎において陰陽消長の変化を表す門という三種の門がある。居室の門を定期的に変更することによって災いを避ける占法は、秦漢時代の風習と風水的認識を反映している。孤虚は天円地方の思想を根底とする占術であり、その天門地戸の意義と吉凶は気に対する認識によって変遷することが見られる。また、随州孔家坡『日書』刑徳六舎と『淮南子』天文訓の刑徳七舎との性質・運行を通じて、先秦数術家の陰陽消息に対する認識を窺える
Delicate Scents : The Emotional and Symbolic Role of Fragrance in Jiang Kuiʼs Baishi Ci Poetry
No full textThis article explores the cultural context of fragrance in classical Chinese literature, focusing on its symbolic significance during the Southern Song Dynasty. The introduction provides insights into the rich traditions and connotations of scent in Chinese literary and cultural practices.
Following this contextual framework, the article attempts a meticulous reading of selected poems from Jiang Kuiʼs (姜夔) renowned collection, Baishi Ci to demonstrate Jiang Kuiʼs sophisticated employment of fragrance as a poetic device and clarify how he weaves scent into the fabric of his verses to create layered meaning and evocative imagery. The discussion then explores the metaphorical depth of Jiang Kuiʼs fragrance depictions to elucidate the complex web of associations and emotions conveyed through his olfactory imagery. This section investigates how Jiang Kuiʼs use of fragrance resonates emotionally with readers, creating a sensory bridge between the physical world and the realm of feelings and memories.
In conclusion, this article offers the broader implications of Kuiʼs innovative approach to fragrance imagery in the context of Chinese literary history
Double-network hydrogels with a gradient hydrophobic coating that prevents water evaporation and allows strong adhesion to a solid substrate
No full textHydrogels are soft and wet polymeric materials containing large amounts of water. The high water content gives hydrogels their unique characteristics, such as biocompatibility. However, the water in the hydrogels easily evaporates under atmospheric conditions. In addition, since hydrogels consist of mostly water, adhering them to solid substrates with commercial glues is difficult. To overcome these problems, we developed a method to apply a robust gradient hydrophobic coating to tough double-network (DN) hydrogels. Liquid hydrophobic monomers were dropped onto the DN gel precursor (the first network gel containing the second network precursor) and spontaneously spread to cover the gel surface. This led to the simultaneous polymerization of the hydrophobic monomer near the gel-air interface and the second network precursor of the bulk gel to yield a gradient hydrophobic coating. The resulting hydrophobic coating effectively prevents water evaporation from the coated DN gel. Moreover, strong adhesion of the coated gel to various solid substrates was achieved with commercial glues
Model-free parameter tuning with continuous genetic algorithm: Application to virtual controlled object-based active vibration controller
No full textActive vibration control is a powerful approach to provide higher damping effects over a broad range of frequencies. However, most of them generally involve a modeling process of a controlled structure, complicating the controller design. The main contribution of this study is to present a novel tuning scheme of a model-free active oscillation controller based on continuous genetic algorithm (CGA), which can simplify a controller design process by eliminating the need for plant modeling. The model-free controller is developed using a virtual controlled object (VCO) as its foundation. VCO makes it possible to construct an active damping controller without knowing any specifications of a real controlled structure. In the offline tuning of the design variables of the controller, we use a reference-controlled object (RCO) - a single-degree-of-freedom (SDOF) structure defined by the designer - to assess the damping level instead of the actual controlled structure model. This evaluation is feasible due to the robustness of the VCO-based design, which accommodates variations in the controlled object structures. The application of the CGA, which has the global search ability, enables automatically specifying the optimal parameter values without costly trial-and-error works. The effectiveness of the auto-optimized model-free damping controller is demonstrated through numerical examples across different mechanical systems, with comparisons made to a trial-and-error-tuned controller. The main finding is that the controller can reduce the vibration amplitudes even though plant modeling of the actual controlled objects is not accompanied at all. As the representative results, the resonance peaks of two different cantilever plates were suppressed by 14.38 and 27.13 dB in the low-frequency band. The detailed-specification-independent nature provided by the model-free design makes it possible to apply the resultant controller to various structures because the robustness is enforced
ドナー抗原特異的免疫抑制性細胞の膵島移植における抗炎症効果 [全文の要約]
No full text配架番号：2885この博士論文全文の閲覧方法については、以下のサイトをご参照ください。https://www.lib.hokudai.ac.jp/dissertations/copy-guides
Usefulness of frailty assessment using the revised Japanese version of the Cardiovascular Health Study on the prediction of clinical outcomes in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement
No full text配架番号：288
Overlooked Parasite Diversity in Staurozoa: Two Species of Lepocreadiidae (Trematoda: Digenea) Parasitic in Haliclystus tenuis
No full textThree non-encysted digenean metacercariae were found parasitic in the mesoglea of two of 13 individuals of the staurozoan cnidarian Haliclystus tenuis Kishinouye, 1910 from Yoichi, Hokkaido, Japan. The metacercariae comprised two morphospecies (one oval, the other elongate), for which the gross morphology is described. Partial sequences of the 18S and 28S rRNA genes and the internal transcribed spacer 2 region were determined for both species, and a partial sequence of the cytochrome c oxidase subunit I gene was determined for the oval species. Molecular phylogenetic analyses revealed both digeneans to be in the family Lepocreadiidae, a taxon not previously reported from staurozoans. The oval species was a member of the “Diploproctodaeum Clade.” The elongate species was identified as Prodistomum orientale (Layman, 1930), known to use marine fishes in the genus Scomber Linnaeus, 1758 as definitive hosts. Second intermediate hosts of P. orientale known around Australia include five hydrozoan, one scyphozoan (Cnidaria), and one ctenophoran species. This is the first information on a second intermediate host from Japan; however, we cannot rule out the possibility that staurozoans may also be dead-end hosts. Including an opecoelid species previously reported, three digenean species in two families are now known from a single staurozoan species in the small region comprising the northwestern coast of Hokkaido. Future surveys for parasites in other staurozoan species and regions will likely detect additional digeneans and other parasite groups utilizing staurozoans
分裂酵母ヘテロクロマチンタンパク質HP1/Swi6によるmat領域の遺伝子再編成制御機構の研究
No full text真核生物のDNAはヒストタンパク質に巻きついたクロマチン構造をとり、核に収納される。ヘテロクロマチンは凝縮した構造をとり、転写に抑制的に機能する。HP1は種を超えて広く保存されたヘテロクロマチンタンパク質であり、ヘテロクロマチン構成主因子として広く知られている。その一方で、HP1のプロテオミクス解析からは転写抑制因子以外の様々なタンパク質と相互作用することが知られており、遺伝子発現抑制以外の機能を持つことが知られている。分裂酵母は2種類の接合型をもち、相同組換えによる遺伝子変換を介して、接合型が一定の頻度で切り替わる。接合型変換に関わる領域の一部はヘテロクロマチンを形成している。分裂酵母においてHP1はSwi6の別名で古くから知られている遺伝子であり、接合型変換（mating-type switching） に関わる因子として同定された経緯がある。swi6+遺伝子破壊株ではヘテロクロマチン構造は崩壊するが、分裂酵母の生育そのものには影響を与えない。本研究では、多くのタンパク質と相互作用することが知られているHP1/Swi6の二量体化ドメインに着目し、ヘテロクロマチン構造には影響を与えないが、生育阻害と接合型変換時に異常な組換えを起こす、非常に特徴的なswi6点変異体を単離した。この変異によりSwi6と相互作用を介して接合型遺伝子座に局在し、接合型変換に重要な機能もつことが知られている組換え関連タンパク質のSwi2との相互作用が無くなっていた。このSwi2のSwi6結合モチーフの変異体でもSwi6変異体と同様の生育阻害がおこる。この生育阻害はSwi2-Swi6相互作用がなくなったときSwi2のAT-hook motif依存的に起きることが明らかになった。AT-hook motifはDNA結合のためのモチーフでありSwi2の接合型遺伝子座での局在に重要である。さらに、生育阻害は接合型遺伝子座の一部が重複した構造（h+N型）をもつ分裂酵母で特定的におこる。以上の結果は、生育阻害が重複した接合型遺伝子座でのSwi2の異常な局在による異常な組換え反応に起因することを示唆しており、Swi2-Swi6の相互作用とAT-hook motifによるDNA認識を介したSwi2のクロマチン局在機構に新しい視点を与えるものである。また、h+N型の分裂酵母は接合型変換が起きずP型の接合型を維持するが、上記のswi6点変異により接合型変換がおきるようになった。遺伝学的解析からswi6点変異体でおきる接合型変換時の異常な組換えはDNAの相同組換え関連タンパク質Rad57に依存することが明らかになった。接合型遺伝子座におけるゲノム構造解析を行ったところ、接合型変換がおきないh+N型の遺伝子座のゲノム構造から接合型変換がおきるh90型への接合型遺伝子座のゲノム構造へと遺伝子の再配列が起きていた。相同組換えタンパク質Rad57が関わっていることを考えると、これは相同組換えの結果起きた遺伝子の再配列だと考えられる。以上のことからSwi6が正常な相同組換えを介した接合型遺伝子座の遺伝子変換において、相互作用するタンパク質の制御を通して統括的に重要な役割を果たしていることを示唆している