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Interactive PDE patch-based surface modeling from vertex-frames
Get PDFYesPolygon, subdivision, and NURBS are three mainstream modeling techniques widely applied in commercial software packages. They require heavy manual operations, and involve a lot of design variables leading to big data, high storage costs and slow network transmissions. In this paper, we integrate the strengths of boundary-based surface creation and partial differential equation (PDE)-based geometric modeling to obtain the first analytical C continuous 4-sided PDE patches involving sculpting force-based shape creation and manipulation and use them to develop an interactive modeling technique for easy and quick creation of 3D models with small data from vertex-frames. With this modeling technique, a vertex frame is defined by eight vertices, and a C continuous 4-sided PDE patch is created from the vertex-frame through an analytical solution to a vector-valued second-order PDE subjected to the boundary conditions determined by the eight vertices of a vertex-frame. A user-friendly interface is developed from the obtained analytical solution, which enables users to interactively input and modify vertex-frame models easily and create 3D models in real time. Different surface modeling tasks are carried out to test the developed interactive tool and compare our proposed method with polygon and NURBS modeling and Coons surfaces. The results demonstrate the effectiveness of our proposed method and its advantages in reducing design variables, saving storage costs, and effective shape creation and manipulation.European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 778035; MCIN/ AEI /10.13039/501100011033/ FEDER “Una manera de hacer Europa
Effects of history, location, and size of ethnic enclaves and ethnic restaurants on authentic cultural and gastronomic experiences
Get PDFYesPurpose – The extant gastronomy literature has rarely examined a connection between authentic gastronomic experiences and destinations. Specifically, ethnic enclaves, which are unique gastronomic and cultural destinations providing ethnic cuisine and cultural experiences to visitors, have been under-researched. Thus, the current study aims to address this knowledge gap.
Design/methodology/approach – Employing a 2 (history: long vs short) x 2 (location: Central Business District [CBD] vs rural; main street vs alleyway) x 2 size/ownership type (big vs small; chain vs independent) between-subjects design, two experiments were conducted using a sample of 557 British consumers to test the effect of history, location, and size of ethnic enclaves and ethnic restaurants on consumers’ authentic cultural and gastronomic experiences in a UK context.
Findings – In Study 1, ethnic enclave’s size affected consumers’ authentic cultural experiences. In Study 2, restaurants’ history and ownership type positively influenced consumers’ authentic gastronomic experiences. Both studies consistently reported the positive relationship between authentic experiences and behavioral intentions.
Practical implications – For ethnic enclaves, the management team may consider expanding the size of ethnic enclaves to increase consumers’ authentic cultural experience. For those ethnic restaurants within the ethnic enclave, any independent or old ethnic restaurants should actively promote both characteristics in their marketing materials to create a feeling of offering authentic gastronomic experiences to customers.
Originality/value – This study identified important ethnic enclave-related factors and ethnic restaurant-related factors forming consumers’ authentic cultural and gastronomic experiences
Using personalized avatars as an adjunct to an adult weight loss management program: randomized controlled feasibility study
Get PDFYesObesity is a global public health concern. Interventions rely predominantly on managing dietary intake and increasing physical activity; however, sustained adherence to behavioral regimens is often poor. The lack of sustained motivation, self-efficacy, and poor adherence to behavioral regimens are recognized barriers to successful weight loss. Avatar-based interventions achieve better patient outcomes in the management of chronic conditions by promoting more active engagement. Virtual representations of self can affect real-world behavior, acting as a catalyst for sustained weight loss behavior.
We evaluated whether a personalized avatar, offered as an adjunct to an established weight loss program, can increase participant motivation, sustain engagement, optimize service delivery, and improve participant health outcomes.
A feasibility randomized design was used to determine the case for future development and evaluation of avatar-based technology in a randomized controlled trial. Participants were recruited from general practitioner referrals to a 12-week National Health Service weight improvement program. The main outcome measure was weight loss. Secondary outcome measures were quality-of-life and self-efficacy. Quantitative data were subjected to descriptive statistical tests and exploratory comparison between intervention and control arms. Feasibility and acceptability were assessed through interviews and analyzed using framework approach. Health Research Authority ethics approval was granted.
Overall, 10 men (n=7, 70% for routine care and avatar and n=3, 30% for routine care) and 33 women (n=23, 70% for intervention and n=10, 30% for routine care) were recruited. Participants' initial mean weight was greater in the intervention arm than in the routine care arm (126.3 kg vs 122.9 kg); pattern of weight loss was similar across both arms of the study in T0 to T1 period but accelerated in T1 to T2 period for intervention participants, suggesting that access to the self-resembling avatar may promote greater engagement with weight loss initiatives in the short-to-medium term. Mean change in participants' weight from T0 to T2 was 4.5 kg (95% CI 2.7-6.3) in the routine care arm and 5.3 kg (95% CI 3.9-6.8) in the intervention arm. Quality-of-life and self-efficacy measures demonstrated greater improvement in the intervention arm at both T1 (105.5 for routine care arm and 99.7 for intervention arm) and T2 (100.1 for routine care arm and 81.2 for intervention arm). Overall, 13 participants (n=11, 85% women and n=2, 15% men) and two health care professionals were interviewed about their experience of using the avatar program.
Participants found using the personalized avatar acceptable, and feedback reiterated that seeing a future self helped to reinforce motivation to change behavior. This feasibility study demonstrated that avatar-based technology may successfully promote engagement and motivation in weight loss programs, enabling participants to achieve greater weight loss gains and build self-confidence.
ISRCTN Registry 17953876; https://doi.org/10.1186/ISRCTN17953876.This study was funded by the National Institute for Health Research (Research for Patient Benefit program [project reference PB-PG-1215-20016])
The role of power-based behaviours in pharmaceutical supply chain resilience
No full textYesPurpose
This study explored the effect of power-based behaviours on pharmaceutical supply chain (PSC) resilience.
Design/methodology/approach
This study used a mixed-method approach to explore the role of power-based behaviours in PSC resilience. Qualitative interviews from 23 key PSC stakeholders, followed by thematic analysis, revealed the underlying perceptions regarding PSC resilience. Quantitative propositions were then developed based on the themes adopted from PSC resilience literature and the qualitative findings. These were tested via a survey questionnaire administered to 106 key stakeholders across the various levels in the PSC. Structural equation modelling with partial least squares was used to analyse the data.
Findings
The data analysed identified proactive and reactive strategies as resilience strategies in the PSC. However, power-based behaviours represented by quota systems, information and price control influenced these resilience strategies. From a complex adaptive system (CAS) perspective, we found that when power-based behaviours were exhibited, the interactions between PSC actors were mixed. There was a negative influence on reactive strategies and a positive influence on proactive strategies. Our analysis also showed that PSC complexities measured by (stringent regulations, long lead times and complex production) moderated the effect of power-based behaviour on reactive strategies. Thus, the negative impact of power-based behaviours on reactive strategies stemmed from PSC complexities.
Research implications
Our research particularly reveals the role of power-based behaviours in building PSC resilience. By evaluating the nexus from a CAS perspective, the analysis considered powerbased behaviours and the moderating role of PSC complexities in developing resilience strategies. The study considers the interactions of PSC actors. It shows that power asymmetry is a relational concept that inhibits the efficacy of reactive strategies. This study thus advocates the importance of power in achieving a more resilient PSC from a holistic perspective by highlighting the importance of the decision-making process among supply chain partners. Our findings are particularly relevant if PSC resilience is viewed as a complex adaptive system (CAS). All the interactions and decision-making processes affect outcomes due to their inherent complexities. Although this study focused on the PSC, its implications could be extended to other SCs (supply chains).
Practical implications
We identified that power-based behaviours influenced resilience strategies. It was detrimental to reactive strategies due to the complexities of the PSC but beneficial to proactive strategies through resource-sharing. PSC actors are therefore encouraged to pursue proactive strategies as this may aid in mitigating the impact of disruptions. However, power-based behaviours bred partner dissatisfaction. This dissatisfaction may occur even within strategic alliances indicating that power could be detrimental to proactive strategies. Therefore, it is pertinent to identify conditions that lead to dissatisfaction when pursuing strategic partnerships. This study provides insight into actual behaviours influencing resilience and quantifies their effects on the PSC. These insights will be valuable for all supply chain partners wanting to improve their resilience strategies.
Originality/value
Previous PSC management and resilience studies have not examined the role of power in building resilience in the PSC. This paper thus provides a unique contribution by identifying the role of power in PSC resilience, offers empirical evidence and a novel theoretical perspective for future practice and research in building PSC resilience strategies
Patient and public co-creation of healthcare safety and healthcare system resilience: The case of COVID-19
Get PDFYesHealthcare system resilience is a conceptual approach that seeks to explore how health services adapt and respond to variability in demand and resources. As has been witnessed since the beginning of the COVID-19 pandemic, healthcare services have undergone many reconfigurations. One understudied aspect of how the 'system' is able to adapt and respond is the contribution of key stakeholders-patients and families, and in the context of the pandemic, the general public as a whole. This study aimed to understand what people were doing during the first wave of the pandemic to protect the safety of their health, and the health of others from COVID-19, and the resilience of the healthcare system.
Social media (Twitter) was used as a method of recruitment due to its ability for social reach. Twenty-one participants took part in 57 semistructured interviews over three time points from June to September 2020. The included an initial interview and invitation to two follow-up interviews after 3 and 6 weeks. Interviews were conducted virtually using Zoom-an encrypted secure video conferencing software. A reflexive thematic analysis approach to analysis was used.
Three themes, each with its own subthemes were identified in the analysis: (1) A 'new safety normal'; (2) Existing vulnerabilities and heightened safety and (3) Are we all in this together?
This study found that the public had a role in supporting the resilience of healthcare services and systems during the first wave of the pandemic by adapting their behaviour to protect themselves and others, and to avoid overwhelming the National Health Service. People who had existing vulnerabilities were more likely to experience safety gaps in their care, and be required to step in to support their safety, despite it being more difficult for them to do so. It may be that the most vulnerable were previously required to do this extra work to support the safety of their care and that the pandemic has just illuminated this issue. Future research should explore existing vulnerabilities and inequalities, and the heightened safety consequences created by the pandemic.
The National Institute for Health Research (NIHR) Yorkshire and Humber Patient Safety Translational Research Centre (NIHR Yorkshire and Humber PSTRC), Patient and Public Involvement and Engagement Research Fellow and NIHR Yorkshire and Humber PSTRC Patient Involvement in Patient Safety theme lay leader are involved in the preparation of a lay version of the findings within this manuscript
The Politics of Women, Peace, and Security: National Action Plan Formulation, Implementation, Monitoring and Evaluation in 19 European Union Countries
No full textThis dissertation examines National Action Plan (NAP) processes for 19 European Union
(EU) countries (Austria, Belgium, Croatia, the Czech Republic, Denmark, Estonia,
Finland, France, Germany, Ireland, Italy, Lithuania, the Netherlands, Poland, Portugal,
Romania, Slovenia, Spain, and Sweden). The study explores how EU NAPs on Women,
Peace and Security (WPS) are being formulated, implemented, monitored, and evaluated
as part of agenda setting, policy formulation and legitimation, policy implementation, and
policy evaluation. Methodologically, it applies the stages model of public policy process
analysis. The research employs a qualitative interpretative research design to identify the
main actors involved in EU country-level NAPs, how these actors are working together,
and how they perceive the successes and challenges of implementing the WPS agenda.
Over 100 key WPS actors and stakeholders from EU NAP circles have been identified –
using expert, purposive, non-probability sampling – and were interviewed. An exploratory
sequential design relies on WPS publications (particularly post the 2015 UN Women
Global Study) to inform these findings. This research approach is, therefore, conceptual,
normative, and empirical. This study explores the extent to which civil society is a part of
EU NAP processes, and whether collaboration on WPS is happening across EU borders
and at the EU regional level. The research sheds light on EU countries’ NAP processes
and approaches, and assesses countries’ overall efforts with the Women, Peace, and
Security agenda
Nanomedicines targeting the inflammasome as a promising therapeutic approach for cell senescence
No full textYesTechnological advancements in the present era have enhanced drug discovery and development. Nanomedicines are valuable pharmacotherapeutic tools against several diseases and disorders including aging related disorders. The mechanistic association between nanomedicines and molecular modulation have been investigated by many researchers. Notwithstanding the availability of tremendous amount of data, role of nanomedicines in aging related disorders intending inflammasome transfiguration have not been thoroughly reviewed till now. In the present review, we discuss the application of nanomedicines in aging related disorders. Further, we highlight the recent updates on modulated upstream and downstream signalling molecules of inflammasome cascade due to nanomedicines. The review will benefit researchers targeting nanomedicines as a therapeutic approach towards treatment age related disorders through inflammasome inflection.Swati Chaturvedi acknowledges the Analytical Chemistry Trust Fund, UK and the Royal Society of Chemistry, UK for providing the Developing World Scholarship
A Jug-Shaped CPW-Fed Ultra-Wideband Printed Monopole Antenna for Wireless Communications Networks
Get PDFYesA type of telecommunication technology called an ultra-wideband (UWB) is used to provide a typical solution for short-range wireless communication due to large bandwidth and low power consumption in transmission and reception. Printed monopole antennas are considered as a preferred platform for implementing this technology because of its alluring characteristics such as light weight, low cost, ease of fabrication, integration capability with other systems, etc. Therefore, a compact-sized ultra-wideband (UWB) printed monopole antenna with improved gain and efficiency is presented in this article. Computer simulation technology microwave studio (CSTMWS) software is used to build and analyze the proposed antenna design technique. This broadband printed monopole antenna contains a jug-shaped radiator fed by a coplanar waveguide (CPW) technique. The designed UWB antenna is fabricated on a low-cost FR-4 substrate with relative permittivity of 4.3, loss tangent of 0.025, and a standard height of 1.6 mm, sized at 25 mm × 22 mm × 1.6 mm, suitable for wireless communication system. The designed UWB antenna works with maximum gain (peak gain of 4.1 dB) across the whole UWB spectrum of 3–11 GHz. The results are simulated, measured, and debated in detail. Different parametric studies based on numerical simulations are involved to arrive at the optimal design through monitoring the effects of adding cuts on the performance of the proposed antennas. Therefore, these parametric studies are optimized to achieve maximum antenna bandwidth with relatively best gain. The proposed patch antenna shape is like a jug with a handle that offers greater bandwidth, good gain, higher efficiency, and compact size
Limited receipt of support services among people with mild-to-moderate dementia: findings from the IDEAL cohort
Get PDFYesGlobal initiatives that promote public health responses to dementia have resulted in numerous countries developing new national policies. Current policy guidelines in England, for example, recommend that people diagnosed with mild-to-moderate dementia receive information and psychosocial interventions to improve their ability to ‘live well’. However, it remains unclear to what extent these recommendations are being achieved.
Methods: Self-reported information from 1537 people living with dementia and informant-reported information from 1277 carers of people living with dementia was used to quantify receipt of community-based dementia support services, including health and social care services provided by statutory or voluntary-sector organisations, in Britain from 2014 to 2016. Demographic factors associated with differences in receipt of support services were also investigated to identify particularly vulnerable groups of people living with dementia.
Results: Both self- and informant reports suggested that approximately 50% of people living with dementia received support services for dementia. Receipt of support services was lower among people living with dementia who are older, female, and have fewer educational qualifications. Receipt of support services also differed according to diagnosis and carer status, but was unrelated to marital status.
Conclusions: Limited receipt of dementia support services among people living with dementia in Britain provides a baseline to assess the efficacy of current policy guidelines regarding provision of information and support. Targeted efforts to facilitate receipt of support services among the particularly vulnerable groups identified in the current study could improve the efficacy of dementia support services both in Britain and internationally, and should inform policy development.The IDEAL study’ was funded jointly by the Economic and Social Research Council (ESRC) and the National Institute for Health Research (NIHR) through grant ES/L001853/2. The IDEAL‐2 study’ is funded by Alzheimer's Society, grant number 348,AS‐PR2‐16‐001
Crude and Primitive? Rethinking the dating and construction of dug-out church chests in Britain
Get PDFYesChests were a ubiquitous part of medieval church furniture across Britain and Europe. Late
19th and early 20th century scholars believed that one type, the dug-out chest, was devoid of
technical skill, and as such, confined to the earliest period of chest chronology. Perhaps as a
result of the ‘primitive’ label, dug-outs remain relatively under-studied in relation to other
types of chests and surprisingly few attempts have been made to validate ideas about their
early origin through scientific dating. The current study uses dendrochronology to directly
date a selection of dug-out chests, almost doubling the number of dated chests of this type in
England and producing the earliest absolute dates for their construction. Five dug-out chests
from the case-study counties of Herefordshire and Worcestershire returned dates ranging
from the 13th-16th century, showing that they are not chronologically confined to the
‘earliest’ period. This research also demonstrates how analysing extant saw-marks, along
with the different methods of attaching chest lids, can assist in dating a chest’s construction.
By understanding the tools and processes of construction, this research challenges the
existing accepted framework that dug-outs are the ‘crudest’ and ‘most primitive’ type of
church chest in the medieval period. Together these findings offer a new methodology and
framework for studies of church chests in Britain and Europe.This paper is based on research undertaken by Rachel Sycamore, as part of a Master’s by Research, at the University of Worcester (Sycamore, 2021). Funding for the dendrochronology was provided by the Regional Furniture Society