95 research outputs found
Numerical analysis of conjugate heat transfer due to oblique impingement of turbulent slot jet onto a flat plate
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A Geospatial Approach to Analyze the Impact of Population Growth on Bundelkhand Landscape, Central India
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THE ROLE OF B CELLS IN THE T CELL DEPENDENT RELEASE OF HUMAN B CELL GROWTH FACTOR
No full textQuiescent human B cells are postulated to go through activation and proliferation phases before undergoing differentiative phase for immunoglobulin secretion. The present studies address some of the aspects of activation and proliferation phase of normal human B cells. The definitions of signals responsible for B cell activation and proliferation resulted in the development of a highly specific, reproducible B cell growth factor (BCGF) assay. This BCGF bioassay utilizes activation by rabbit anti-human IgM-antibody. The functional specificity of this assay for measuring BCGF activity was demonstrated by the finding that target B cells proliferated but did not differentiate. The factor specificity was determined by specific absorption of BCGF by anti-IgM activated B cells. This assay was utilized for the studies of T-B cell collaboration and the essential function of monocytes in the production and/or release of B cell growth factor in a syngeneic in vitro system. It is apparent that highly purified T cells are poor producers of BCGF by themselves and require monocytes to secrete significant quantities of BCGF upon PHA stimulation. Macrophage soluble factor, Interleukin 1, is capable of replacing monocyte function for the release of BCGF by activated T cells. In our studies, B cells are incapable to function as accessory cells to replace monocyte function. Normal B cells are also not capable of producing BCGF under our experimental observations. However, the addition of these B cells at an optimum cell density (T:B ratio 1:1) doubles the monocyte dependent release of BCGF by syngeneic T cells. The augmentative role of B cells is expanded to understand the mechanism of BCGF release by T cells. It is observed from our studies that DR antigen of B cell surface is involved in the release of BCGF. The functional difference between DR of B cells and monocytes is observed as IL-1 could replace DR-treated monocytes whereas failed to replace DR-treated B cells for the release of BCGF by T cells. This functional difference may be attributed to the reported microheterogeneity in DR of B cells and monocytes. The addition of irradiated B cells increased the monocyte dependent T cell proliferation, suggesting the increase of T cell pool for BCGF release. In summary, the development of a biological assay specific for B cell growth factor led to the delineation of an interesting role of B cells in the release of its own growth factor by T cells. . . . (Author\u27s abstract exceeds stipulated maximum length. Discontinued here with permission of author.) UM
Medicinal Value of Curcuma cassia roxb: An Overview
No full textCurcuma caesia is commonly known as kali haldi and it belongs to the family Zingiberaceae. Black turmeric is an uncommon endemic as well as ethno medicinally important of South East Asia. This herb is available throughout north-east, central India, Papi Hills of East Godavari, West Godavari, and Andhra Pradesh. In the traditional system of medicine, fresh and dried rhizomes of Curcuma caesia are used in treating leucoderma, asthma, tumours, piles, bronchitis, bruises etc. Curcuma caesia has scientifically studied for various therapeutical activities like antioxidant, antibacterial, antipyretic, larvicidal, insecticidal, antimicrobial, wound healing and anti-hyperglycaemic. The present review is an effort to give a detailed survey of the literature on its, phytochemistry, traditional uses and therapeutical studies.</jats:p
Sustainable Development Strategies and Approaches
No full text<p>This paper on sustainable development strategies and Approaches is an attempt to get a holistic view of the sustainable development and how this can be achieved through the integrated development approach at various levels. The paper starts with understanding the definition of the sustainable development and they the author attempt to analyze the sustainable development strategies and approaches at different levels. Starting with building and moving towards sustainable neighbourhood and then towards the sustainable urban and regional areas is a good attempt to get an overall approach to the sustainable development rather than thinking about the different links and missing out the final goal and objectives of the sustainable development. Readers will find this article to get the overall picture that emerges after the continued efforts at different levels, international, national level, regional, neighbourhood and building level in such a lucid manner that any non-technical person can easily understand the concept of the sustainable development and various prevalent sustainable development strategies and approaches.</p>
Studies of a Supported Titanium Catalyst System Using Magnesium Dichloride–Alcohol Adduct
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Comparative analysis of coverage aspects for various LEDs placement schemes in indoor vlc system
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