51 research outputs found

    Regarding: Nicotinic acetylcholine receptors α7 and α9 modify tobacco smoke risk for multiple sclerosis.

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    This is a author manuscript of an article accepted for publication in Multiple Sclerosis Journal. Version of record is available online at Jacobs BM, Smets I, Giovannoni G, Noyce A, Jokubaitis V, Dobson R. Regarding: Nicotinic acetylcholine receptors α7 and α9 modify tobacco smoke risk for multiple sclerosis. Multiple Sclerosis Journal. December 2020. doi:10.1177/1352458520969941. Copyright (c) 2020. The Authors. doi:10.1177/135245852096994

    Traumatic Experiences In “Salt” Movie Directed By Phillip Noyce (2010): A Psychoanalytic Approach

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    This research is proposed to analyze traumatic experiences in a film with title Salt using Psychoanalytic Approach. There are two objectives. The first is to analyze the film in term of structural analysis and the second is to analyze the film based on Psychoanalytic Approach. The research paper belongs to the qualitative research. The object of the study is the personality of Evelyn in Salt movie. There are two kinds of data sources used in this research, they are primary and secondary. The primary data is the film itself and the secondary data sources are biography of the author, books and internet. The technique of data collection in this research is summarizing, paraphrasing, and documenting the data. In analyzing the data, the writer employs descriptive qualitative analysis Based on the structural analysis it is evident that in this movie, Phillip Noyce wants to deliver a message that an experience should be a lesson in the future. The structural elements are related to each other and form a unity. Based on the psychological analysis, it is clear that in Salt movie Phillip Noyce describes a psychological phenomenon, in which the major characters Evelyn Salt has some traumatic experience

    A growing Noyce Scholarship Program: successes, triumphs and challenges along the way

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    Purpose – The article discusses the development and growth of a newly established Noyce Scholarship Program at a Hispanic Serving Institution and the collaborative efforts of the School of Education (SOE) and its partners during the recruitment and retention process. Design/methodology/approach – The author will explore and answer questions: (1) What were the articulated agreements implemented during the recruitment and application process? (2) In what ways did the scholar’s professional growth benefit from the dedicated and shared resources of the SOE’s partners? (3) How did the process of mentoring transform into a collaborative research effort resulting in presentation experiences? Findings – The balance of triumphs, challenges and success in the program allows room for growth and reflection. Once scholars were admitted and accepted into the program, various supports were implemented to ensure scholars would be given tools needed to become highly effective educators in high-needs schools. In an informal discussion with scholars, they indicated the program taught them the necessary tools and dispositions needed to effectively teach the curriculum in STEM-based classrooms. However, they believed the issues of the program could be solved through constant communication and consideration of scholar input. Scholars also expressed appreciation for experiences encountered for scholar success. Originality/value – The Noyce Scholars Program has provided opportunities for STEM majors to demonstrate hope and vision regarding the teacher shortage, particularly in STEM areas. The story of a professional development school’s unpredictable journey in addressing the teacher pipeline will hopefully be a source of valuable information for other Professional Development School (PDS) partnerships. Recruitment, clinical preparation and continuous support of partners will continue to be integral factors in shaping future efforts to address the STEM teacher shortage creating a better world, locally and globally

    The September 23 issue of Maine Times contained a piece on a Maine Public Televi

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    The September 23 issue of Maine Times contained a piece on a Maine Public Television documentary on the Mears Cove housing project in Damariscotta. The piece resulted in the project being discussed on the September 24 broadcast of Media Watch, with commentator Tom Hanrahan lashing out at Maine Public Broadcasting Corporation trustees Elizabeth Noyce and author Tabitha King. Noyce has resigned from the board because of the treatment, and MPBC has instituted a set of standards outlawing personal attacks and insulting language. Details

    Evaluating lipid-lowering drug targets for Parkinson’s disease prevention with Mendelian randomization

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    Long‐term exposure to lipid‐lowering drugs might affect Parkinson's disease (PD) risk. We conducted Mendelian randomization analyses where genetic variants indexed expected effects of modulating lipid‐lowering drug targets on PD. Statin exposure was not predicted to increase PD risk, although results were not precise enough to support benefits for prevention clearly (odds ratio [OR] = 0.83; 95% confidence interval [CI] = 0.65, 1.07). Other target results were null, except for variants indicating Apolipoprotein‐A5 or Apolipoprotein‐C3 inhibition might confer protection. These findings suggest peripheral lipid variation may not have a prominent role in PD etiology, but some related drug targets could influence PD via alternate pathways

    Patient perceptions of treatment and illness when prescribed multiple medicines for co-morbid type 2 diabetes

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    Illness and treatment perceptions are vital for people self-managing co-morbid conditions with associated cardiovascular disease, such as type 2 diabetes (T2D). However, perceptions of a co-morbid condition and the use of multiple medicines have yet to be researched. This study investigated the illness and treatment perceptions of people with co-morbid T2D. The Brief Illness Perception Questionnaire (repeated for T2D, hypertension, and hyperlipidemia) and the Beliefs about Medicines Questionnaire Specific Concerns Scales (repeated for Oral hypoglycemic agents, anti-hypertensive medicines, and statins) were sent to 480 people managing co-morbid T2D. Data on the number of medicines prescribed were collected from medical records. Significantly different perceptions were found across the illnesses. The strongest effect was for personal control; the greatest control reported for T2D. Illness perceptions of T2D differed significantly from perceptions about hyperlipidemia. Furthermore, illness perceptions of T2D also differed from perceptions of hypertension with the exception of perceptions of illness severity. Hypertension and hyperlipidemia shared similar perceptions about comprehensibility, concerns, personal control, and timeline. Significant differences were found for beliefs about treatment necessity, but no difference was found for treatment concerns. When the number of medicines was taken as a between-subjects factor, only intentional non-adherence, treatment necessity beliefs, and perceptions of illness timeline were accounted for. Co-morbid illness and treatment perceptions are complex, often vary between illnesses, and can be influenced by the number of medicines prescribed. Further research should investigate relationships between co-morbid illness and treatment perception structures and self-management practices

    Visions and prophecies in the sapiential tradition from Proverbs to modernity

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    This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field

    The American Homophilic School of Composition

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    A small enclave of gay composers in New York, led by Aaron Copland (1900-1990) and Virgil Thomson (1896-1989), established a distinct twentieth-century musical sound that became synonymous with America. Copland and Thomson were prominent among a group of gifted gay musicians and conductors in New York in the 1930s, 40s and 50s. While perhaps not self-identifying as gay, as the term had not yet been coined, they did however acknowledge, honor, and support one another\u27s lives as being homosexual. Is it possible that something as seemingly unrelated as sexual preference could, in fact, impact a musical style? In this document, the author will consider what these great composers\u27 homosexuality may have had to do with their music making and how their gay social network--specifically during the height of the American Homophile Movement--supported a form of expression that directly influenced one another\u27s compositional techniques. In addition to examining well-known works, the author will focus on two specific works for flute, Copland\u27sDuo for Flute and Pianoand Thomson\u27sSonata for Flute Alone.The exploration of these works, and the highlighting of the many similarities between them, will serve as an example of the mutual, homophilic influence these composers had upon one another. Arguably, Aaron Copland is considered one of America\u27s most notable composers. For many people, his music has become synonymous with American pride and culture in the twentieth century. It may be heard today in television advertisements and movie trailers as well in concert halls, and is often used to evoke an American spirit. In fact, it has been called the quintessential American sound by many critics and commentators. Virgil Thomson, composer and music critic for theNew York Herald Tribune,also had significant influence in the development of a uniquely recognizable American sound. However, the compositions of Thomson are often eclipsed by, and do not retain the equivalent and widespread notoriety, of the compositions of Copland. What is often misunderstood today is that the unique quality of composition that Thomson began, while collaborating with famed lesbian writer Gertrude Stein on the operaFour Saints in Three Acts,greatly influenced the compositional style of Aaron Copland

    Constructing the processes involved in ending therapy with clients

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    Understanding the processes involved in therapy are crucial to maximising its benefits. This doctoral thesis explores two aspects of therapy which are crucial to the beginning and ending phases of therapy i.e. the formation of the therapeutic relationship and the experience of ending therapy. It is hoped that this contribution to the research base will provide clinicians with practical recommendations based on empirical evidence and prompt future research to investigate these topics further. The first section of this thesis describes a metasynthesis of qualitative studies exploring the formation of the therapeutic relationship from the client’s perspective. Findings highlight clients’ initial assessment of therapist characteristics to see whether they fit with their perceived needs. Displays of openness and respect from the therapist were found to facilitate the formation of the relationship and allow for a deep connection between client and therapist to be established. The second section of this thesis presents a grounded theory study focusing on therapists’ experiences of ending therapy with clients. The theory explains the processes that play a significant role in the ending experience (therapist context, therapeutic approach, level of connectedness, level of investment and therapist’s perceived responsibility) and how they impact on different types of therapy endings. Elements of the therapy were found to continue beyond the final session as therapists described learning from each ending experience which served to influence their future work with clients. The third section of this thesis comprises personal reflections on the process of engaging in the thesis project. Specifically, this critical appraisal explores the difficulties experienced by the author in positioning herself within a consistent ontological and epistemological stance. The reflections offered in this section follow the developmental journey made by the author as a result of engaging in this project

    Author Correction: The IPDGC/GP2 Hackathon - an open science event for training in data science, genomics, and collaboration using Parkinson’s disease data

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    Correction to: npj Parkinson’s Disease https://doi.org/10.1038/s41531-023-00472-6, published online 04 March 2023// In this article the affiliation details for Alastair J Noyce, Jonggeol Jeff Kim, Isabelle Francesca Foote, Sumit Dey were incorrectly given as ‘Department of Genetics and Genomic Sciences and Mindich Child Health and Development Institute, Icahn School of Medicine at Mount, Hess Center for Science and Medicine, New York, NY 10029, USA,’ but should have been ‘Preventive Neurology Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK’.// The affiliation details for Prabhjyot Saini were incorrectly given as ‘Preventive Neurology Unit, Wolfson Institute of Population Health, Queen Mary University of London, London, UK’ but should have been ‘The Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, QC, Canada’. The original article has been corrected
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