3,293 research outputs found
Uniform Consistency for Nonparametric Estimators in Null Recurrent Time Series
This paper establishes several results for uniform convergence of nonparametric kernel density and regression estimates for the case where the time series regressors concerned are nonstationary null–recurrent Markov chains. Under suitable conditions, certain rates of convergence are also established for these estimates. Our results can be viewed as an extension of some well–known uniform consistency results for the stationary time series to the nonstationary time series case.beta–null recurrent Markov chain; nonparametric estimation; rate of convergence, uniform consistency
PsdR-expressing strain exhibits LasR-null-like phenotypes.
(A-C) PsdR-expressing strain produces metabolites to the levels similar to the LasR-null mutant. (A) Pyocyanin production (OD695/OD600 values) in shown strains. (B) Elastase production (OD495/OD600 values) in these strains. (C) The relative concentrations of hydrogen cyanide in shown strains. A one-way ANOVA with Bonferroni posttest was used for statistical analysis (n.s., not significant). (TIF)</p
ESPnet2 pretrained model, Chenda Li/wsj0_2mix_enh_train_enh_conv_tasnet_raw_valid.si_snr.ave, fs=8k, lang=en
This model was trained by Chenda Li using wsj0_2mix recipe in espnet.
Python API
See https://github.com/espnet/espnet_model_zoo
Evaluate in the recipe
git clone https://github.com/espnet/espnet
cd espnet
git checkout a3334220b0352931677946d178fade3313cf82bb
pip install -e .
cd egs2/wsj0_2mix/enh1
./run.sh --skip_data_prep false --skip_train true --download_model Chenda Li/wsj0_2mix_enh_train_enh_conv_tasnet_raw_valid.si_snr.ave
Results
# RESULTS
## Environments
- date: `Thu Feb 4 01:16:18 CST 2021`
- python version: `3.7.6 (default, Jan 8 2020, 19:59:22) [GCC 7.3.0]`
- espnet version: `espnet 0.9.7`
- pytorch version: `pytorch 1.5.0`
- Git hash: `a3334220b0352931677946d178fade3313cf82bb`
- Commit date: `Fri Jan 29 23:35:47 2021 +0800`
## enh_train_enh_conv_tasnet_raw
config: ./conf/tuning/train_enh_conv_tasnet.yaml
|dataset|STOI|SAR|SDR|SIR|
|---|---|---|---|---|
|enhanced_cv_min_8k|0.949205|17.3785|16.8028|26.9785|
|enhanced_tt_min_8k|0.95349|16.6221|15.9494|25.9032|
ASR config
config: ./conf/tuning/train_enh_conv_tasnet.yaml
print_config: false
log_level: INFO
dry_run: false
iterator_type: chunk
output_dir: exp/enh_train_enh_conv_tasnet_raw
ngpu: 1
seed: 0
num_workers: 4
num_att_plot: 3
dist_backend: nccl
dist_init_method: env://
dist_world_size: null
dist_rank: null
local_rank: 0
dist_master_addr: null
dist_master_port: null
dist_launcher: null
multiprocessing_distributed: false
cudnn_enabled: true
cudnn_benchmark: false
cudnn_deterministic: true
collect_stats: false
write_collected_feats: false
max_epoch: 100
patience: 4
val_scheduler_criterion:
- valid
- loss
early_stopping_criterion:
- valid
- loss
- min
best_model_criterion:
- - valid
- si_snr
- max
- - valid
- loss
- min
keep_nbest_models: 1
grad_clip: 5.0
grad_clip_type: 2.0
grad_noise: false
accum_grad: 1
no_forward_run: false
resume: true
train_dtype: float32
use_amp: false
log_interval: null
unused_parameters: false
use_tensorboard: true
use_wandb: false
wandb_project: null
wandb_id: null
pretrain_path: null
init_param: []
freeze_param: []
num_iters_per_epoch: null
batch_size: 8
valid_batch_size: null
batch_bins: 1000000
valid_batch_bins: null
train_shape_file:
- exp/enh_stats_8k/train/speech_mix_shape
- exp/enh_stats_8k/train/speech_ref1_shape
- exp/enh_stats_8k/train/speech_ref2_shape
valid_shape_file:
- exp/enh_stats_8k/valid/speech_mix_shape
- exp/enh_stats_8k/valid/speech_ref1_shape
- exp/enh_stats_8k/valid/speech_ref2_shape
batch_type: folded
valid_batch_type: null
fold_length:
- 80000
- 80000
- 80000
sort_in_batch: descending
sort_batch: descending
multiple_iterator: false
chunk_length: 32000
chunk_shift_ratio: 0.5
num_cache_chunks: 1024
train_data_path_and_name_and_type:
- - dump/raw/tr_min_8k/wav.scp
- speech_mix
- sound
- - dump/raw/tr_min_8k/spk1.scp
- speech_ref1
- sound
- - dump/raw/tr_min_8k/spk2.scp
- speech_ref2
- sound
valid_data_path_and_name_and_type:
- - dump/raw/cv_min_8k/wav.scp
- speech_mix
- sound
- - dump/raw/cv_min_8k/spk1.scp
- speech_ref1
- sound
- - dump/raw/cv_min_8k/spk2.scp
- speech_ref2
- sound
allow_variable_data_keys: false
max_cache_size: 0.0
max_cache_fd: 32
valid_max_cache_size: null
optim: adam
optim_conf:
lr: 0.001
eps: 1.0e-08
weight_decay: 0
scheduler: reducelronplateau
scheduler_conf:
mode: min
factor: 0.5
patience: 1
init: xavier_uniform
model_conf:
loss_type: si_snr
use_preprocessor: false
encoder: conv
encoder_conf:
channel: 256
kernel_size: 20
stride: 10
separator: tcn
separator_conf:
num_spk: 2
layer: 8
stack: 4
bottleneck_dim: 256
hidden_dim: 512
kernel: 3
causal: false
norm_type: gLN
nonlinear: relu
decoder: conv
decoder_conf:
channel: 256
kernel_size: 20
stride: 10
required:
- output_dir
version: 0.9.7
distributed: fals
ESPnet2 pretrained model, Chenda Li/wsj0_2mix_enh_train_enh_rnn_tf_raw_valid.si_snr.ave, fs=8k, lang=en
This model was trained by Chenda Li using wsj0_2mix recipe in espnet.
Python API
See https://github.com/espnet/espnet_model_zoo
Evaluate in the recipe
git clone https://github.com/espnet/espnet
cd espnet
git checkout a3334220b0352931677946d178fade3313cf82bb
pip install -e .
cd egs2/wsj0_2mix/enh1
./run.sh --skip_data_prep false --skip_train true --download_model Chenda Li/wsj0_2mix_enh_train_enh_rnn_tf_raw_valid.si_snr.ave
Results
# RESULTS
## Environments
- date: `Thu Feb 4 01:08:19 CST 2021`
- python version: `3.7.6 (default, Jan 8 2020, 19:59:22) [GCC 7.3.0]`
- espnet version: `espnet 0.9.7`
- pytorch version: `pytorch 1.5.0`
- Git hash: `a3334220b0352931677946d178fade3313cf82bb`
- Commit date: `Fri Jan 29 23:35:47 2021 +0800`
## enh_train_enh_rnn_tf_raw
config: conf/tuning/train_enh_rnn_tf.yaml
|dataset|STOI|SAR|SDR|SIR|
|---|---|---|---|---|
|enhanced_cv_min_8k|0.891065|11.556|10.3982|18.0655|
|enhanced_tt_min_8k|0.896373|11.4086|10.2433|18.0496|
ASR config
config: conf/tuning/train_enh_rnn_tf.yaml
print_config: false
log_level: INFO
dry_run: false
iterator_type: sequence
output_dir: exp/enh_train_enh_rnn_tf_raw
ngpu: 1
seed: 0
num_workers: 4
num_att_plot: 3
dist_backend: nccl
dist_init_method: env://
dist_world_size: null
dist_rank: null
local_rank: 0
dist_master_addr: null
dist_master_port: null
dist_launcher: null
multiprocessing_distributed: false
cudnn_enabled: true
cudnn_benchmark: false
cudnn_deterministic: true
collect_stats: false
write_collected_feats: false
max_epoch: 100
patience: 10
val_scheduler_criterion:
- valid
- loss
early_stopping_criterion:
- valid
- loss
- min
best_model_criterion:
- - valid
- si_snr
- max
- - valid
- loss
- min
keep_nbest_models: 1
grad_clip: 5.0
grad_clip_type: 2.0
grad_noise: false
accum_grad: 1
no_forward_run: false
resume: true
train_dtype: float32
use_amp: false
log_interval: null
unused_parameters: false
use_tensorboard: true
use_wandb: false
wandb_project: null
wandb_id: null
pretrain_path: null
init_param: []
freeze_param: []
num_iters_per_epoch: null
batch_size: 8
valid_batch_size: null
batch_bins: 1000000
valid_batch_bins: null
train_shape_file:
- exp/enh_stats_8k/train/speech_mix_shape
- exp/enh_stats_8k/train/speech_ref1_shape
- exp/enh_stats_8k/train/speech_ref2_shape
valid_shape_file:
- exp/enh_stats_8k/valid/speech_mix_shape
- exp/enh_stats_8k/valid/speech_ref1_shape
- exp/enh_stats_8k/valid/speech_ref2_shape
batch_type: folded
valid_batch_type: null
fold_length:
- 80000
- 80000
- 80000
sort_in_batch: descending
sort_batch: descending
multiple_iterator: false
chunk_length: 500
chunk_shift_ratio: 0.5
num_cache_chunks: 1024
train_data_path_and_name_and_type:
- - dump/raw/tr_min_8k/wav.scp
- speech_mix
- sound
- - dump/raw/tr_min_8k/spk1.scp
- speech_ref1
- sound
- - dump/raw/tr_min_8k/spk2.scp
- speech_ref2
- sound
valid_data_path_and_name_and_type:
- - dump/raw/cv_min_8k/wav.scp
- speech_mix
- sound
- - dump/raw/cv_min_8k/spk1.scp
- speech_ref1
- sound
- - dump/raw/cv_min_8k/spk2.scp
- speech_ref2
- sound
allow_variable_data_keys: false
max_cache_size: 0.0
max_cache_fd: 32
valid_max_cache_size: null
optim: adam
optim_conf:
lr: 0.001
eps: 1.0e-08
weight_decay: 1.0e-07
scheduler: reducelronplateau
scheduler_conf:
mode: min
factor: 0.7
patience: 1
init: xavier_uniform
model_conf:
loss_type: mask_mse
mask_type: psm
use_preprocessor: false
encoder: stft
encoder_conf:
n_fft: 256
hop_length: 128
separator: rnn
separator_conf:
rnn_type: blstm
num_spk: 2
nonlinear: relu
layer: 3
unit: 896
dropout: 0.5
decoder: stft
decoder_conf:
n_fft: 256
hop_length: 128
required:
- output_dir
version: 0.9.7
distributed: fals
Intra-cavity spectroscopy using amplified spontaneous emission in fiber lasers
Fiber laser sources offer interesting possibilities for gas sensors since they can operate over an extended wavelength range, encompassing the near-IR absorption lines of a number of important gases but a major problem is that overtone absorption lines of gases in the near-IR are relatively weak. In order to enhance sensitivity, we present here a simple method of intra-cavity absorption spectroscopy (ICAS) which makes use of the amplified spontaneous emission (ASE) already present within a fiber laser cavity. The ASE also provides a convenient broadband source for the simultaneous interrogation of several gases within the gain-bandwidth of the fiber laser. The key principle is based on adjusting the cavity attenuation to select an appropriate inversion level where the fiber gain curve is flat. Under this condition, the ASE undergoes multiple circulations within the fiber laser cavity, enhancing the effective path-length of a gas cell placed within the laser cavity. A theoretical model of system operation is given and we have experimentally demonstrated the principle of operation with acetylene and carbon dioxide using a simple erbium fiber laser system containing a 6 cm path-length, fiber coupled, intra-cavity, micro-optic gas cell. We have experimentally simultaneously observed 16 absorption lines for 1% acetylene gas in the 1530 nm region and detected the very weak carbon dioxide lines in this same wavelength region. A path length enhancement of in the linear regime has been demonstrated transforming the 6 cm micro-optic cell into an effective path length of m. We also demonstrate how the enhancement factor may be calibrated by use of a simple fiber-optic interferometer. Apart from the OSA, all components are inexpensive and the system is very simple to construct and operate
Testing the Parametric Specification of the Diffusion Function in a Diffusion Process
A new consistent test is proposed for the parametric specification of the diffusion function in a diffusion process without any restrictions on the functional form of the drift function. The data are assumed to be sampled discretely in a time interval that can be fixed or lengthened to infinity. The test statistic is shown to follow an asymptotic normal distribution under the null hypothesis that the parametric diffusion function is correctly specified. Monte Carlo simulations are conducted to examine the finite-sample performance of the test, revealing that the test has good size and power.Econometric and statistical methods; Interest rates
ESPnet2 pretrained model, Chenda Li/wsj0_2mix_joint_train_asr_transformer_raw_char_aux_valid.acc.ave, fs=8k, lang=en
This model was trained by Chenda Li using wsj0_2mix recipe in espnet.
Python API
See https://github.com/espnet/espnet_model_zoo
Evaluate in the recipe
git clone https://github.com/espnet/espnet
cd espnet
git checkout 7ee55a382e7b8087daf2434451711855c76aa699
pip install -e .
cd egs2/wsj0_2mix/asr1
./run.sh --skip_data_prep false --skip_train true --download_model Chenda Li/wsj0_2mix_joint_train_asr_transformer_raw_char_aux_valid.acc.ave
Results
# RESULTS
## Environments
- date: `Fri Jun 18 16:47:32 CST 2021`
- python version: `3.7.6 (default, Jan 8 2020, 19:59:22) [GCC 7.3.0]`
- espnet version: `espnet 0.9.9`
- pytorch version: `pytorch 1.7.1`
- Git hash: `7ee55a382e7b8087daf2434451711855c76aa699`
- Commit date: `Fri Jun 18 15:14:28 2021 +0800`
## joint_train_asr_transformer_raw_char_aux
### WER
|dataset|Snt|Wrd|Corr|Sub|Del|Ins|Err|S.Err|
|---|---|---|---|---|---|---|---|---|
exp/joint_train_asr_transformer_raw_char_aux/decode_tt_max_8k_decode_lm_train_lm_char_valid.loss.best_asr_model_valid.acc.ave/score_wer/result.txt:|6000|98613|88.1|10.2|1.7|2.4|14.3|62.1|
exp/joint_train_asr_transformer_raw_char_aux/decode_tt_max_8k_decode_lm_train_lm_char_valid.loss.best_asr_model_valid.acc.best/score_wer/result.txt:|6000|98613|84.1|13.5|2.4|3.3|19.2|68.5|
### CER
|dataset|Snt|Wrd|Corr|Sub|Del|Ins|Err|S.Err|
|---|---|---|---|---|---|---|---|---|
exp/joint_train_asr_transformer_raw_char_aux/decode_tt_max_8k_decode_lm_train_lm_char_valid.loss.best_asr_model_valid.acc.ave/score_cer/result.txt:|6000|598296|94.8|2.9|2.3|2.5|7.7|63.6|
exp/joint_train_asr_transformer_raw_char_aux/decode_tt_max_8k_decode_lm_train_lm_char_valid.loss.best_asr_model_valid.acc.best/score_cer/result.txt:|6000|598296|92.5|4.1|3.4|3.5|11.0|69.5|
ASR config
config: conf/tuning/train_asr_transformer.yaml
print_config: false
log_level: INFO
dry_run: false
iterator_type: sequence
output_dir: exp/joint_train_asr_transformer_raw_char_aux
ngpu: 1
seed: 0
num_workers: 4
num_att_plot: 0
dist_backend: nccl
dist_init_method: env://
dist_world_size: 4
dist_rank: 0
local_rank: 0
dist_master_addr: localhost
dist_master_port: 43100
dist_launcher: null
multiprocessing_distributed: true
unused_parameters: true
sharded_ddp: false
cudnn_enabled: true
cudnn_benchmark: false
cudnn_deterministic: false
collect_stats: false
write_collected_feats: false
max_epoch: 120
patience: null
val_scheduler_criterion:
- valid
- loss
early_stopping_criterion:
- valid
- loss
- min
best_model_criterion:
- - valid
- acc
- max
- - valid
- loss
- min
keep_nbest_models: 10
grad_clip: 3
grad_clip_type: 2.0
grad_noise: false
accum_grad: 4
no_forward_run: false
resume: true
train_dtype: float32
use_amp: false
log_interval: null
use_tensorboard: true
use_wandb: false
wandb_project: null
wandb_id: null
detect_anomaly: false
pretrain_path: null
init_param: []
ignore_init_mismatch: false
freeze_param: []
num_iters_per_epoch: null
batch_size: 4
valid_batch_size: null
batch_bins: 1000000
valid_batch_bins: null
train_shape_file:
- exp/joint_stats_raw_8k_aux/train/speech_mix_shape
- exp/joint_stats_raw_8k_aux/train/utt2category_shape
- exp/joint_stats_raw_8k_aux/train/speech_ref1_shape
- exp/joint_stats_raw_8k_aux/train/text_ref1_shape
- exp/joint_stats_raw_8k_aux/train/speech_ref2_shape
- exp/joint_stats_raw_8k_aux/train/text_ref2_shape
valid_shape_file:
- exp/joint_stats_raw_8k_aux/valid/speech_mix_shape
- exp/joint_stats_raw_8k_aux/valid/utt2category_shape
- exp/joint_stats_raw_8k_aux/valid/speech_ref1_shape
- exp/joint_stats_raw_8k_aux/valid/text_ref1_shape
- exp/joint_stats_raw_8k_aux/valid/speech_ref2_shape
- exp/joint_stats_raw_8k_aux/valid/text_ref2_shape
batch_type: folded
valid_batch_type: null
fold_length:
- 80000
- 80000
- 80000
- 80000
- 80000
- 80000
sort_in_batch: descending
sort_batch: descending
multiple_iterator: false
chunk_length: 500
chunk_shift_ratio: 0.5
num_cache_chunks: 1024
train_data_path_and_name_and_type:
- - dump/raw/tr_max_8k_train_si284/wav.scp
- speech_mix
- sound
- - dump/raw/tr_max_8k_train_si284/utt2category
- utt2category
- text
- - dump/raw/tr_max_8k_train_si284/spk1.scp
- speech_ref1
- sound
- - dump/raw/tr_max_8k_train_si284/text_spk1
- text_ref1
- text
- - dump/raw/tr_max_8k_train_si284/spk2.scp
- speech_ref2
- sound
- - dump/raw/tr_max_8k_train_si284/text_spk2
- text_ref2
- text
valid_data_path_and_name_and_type:
- - dump/raw/cv_max_8k/wav.scp
- speech_mix
- sound
- - dump/raw/cv_max_8k/utt2category
- utt2category
- text
- - dump/raw/cv_max_8k/spk1.scp
- speech_ref1
- sound
- - dump/raw/cv_max_8k/text_spk1
- text_ref1
- text
- - dump/raw/cv_max_8k/spk2.scp
- speech_ref2
- sound
- - dump/raw/cv_max_8k/text_spk2
- text_ref2
- text
allow_variable_data_keys: false
max_cache_size: 0.0
max_cache_fd: 32
valid_max_cache_size: null
optim: adam
optim_conf:
lr: 0.002
eps: 1.0e-08
weight_decay: 1.0e-07
scheduler: warmuplr
scheduler_conf:
warmup_steps: 45000
enh_model_conf:
loss_type: si_snr
token_list:
-
-
-
- E
- T
- A
- N
- I
- O
- S
- R
- H
- L
- D
- C
- U
- M
- P
- F
- G
- Y
- W
- B
- V
- K
- .
- X
- ''''
- J
- Q
- Z
-
- ','
- '-'
- '"'
- '*'
- ':'
- (
- )
- '?'
- '!'
- '&'
- ;
- '1'
- '2'
- '0'
- /
- $
- '{'
- '}'
- '8'
- '9'
- '6'
- '3'
- '5'
- '7'
- '4'
- '~'
- '`'
- _
-
-
- \
- ^
-
init: xavier_uniform
input_size: null
ctc_conf:
reduce: true
asr_model_conf:
ctc_weight: 0.3
lsm_weight: 0.1
length_normalized_loss: false
joint_model_conf:
enh_weight: 0.8
end2end_train: true
cal_enh_loss: true
use_preprocessor: true
token_type: char
bpemodel: null
non_linguistic_symbols: data/nlsyms.txt
cleaner: null
g2p: null
enh_encoder: conv
enh_encoder_conf:
channel: 256
kernel_size: 20
stride: 10
enh_separator: tcn
enh_separator_conf:
num_spk: 2
layer: 6
stack: 3
bottleneck_dim: 256
hidden_dim: 384
kernel: 3
causal: false
norm_type: gLN
nonlinear: relu
enh_decoder: conv
enh_decoder_conf:
channel: 256
kernel_size: 20
stride: 10
frontend: default
frontend_conf:
fs: 8000
n_fft: 256
win_length: 256
hop_length: 64
apply_stft: true
specaug: null
specaug_conf: {}
normalize: utterance_mvn
normalize_conf: {}
encoder: transformer
encoder_conf:
output_size: 256
attention_heads: 4
linear_units: 1536
num_blocks: 12
dropout_rate: 0.1
positional_dropout_rate: 0.2
attention_dropout_rate: 0.0
input_layer: conv2d
normalize_before: true
decoder: transformer
decoder_conf:
attention_heads: 4
linear_units: 1536
num_blocks: 6
dropout_rate: 0.1
positional_dropout_rate: 0.1
self_attention_dropout_rate: 0.0
src_attention_dropout_rate: 0.0
required:
- output_dir
- token_list
version: 0.9.9
distributed: true
LM config
config: conf/tuning/train_lm.yaml
print_config: false
log_level: INFO
dry_run: false
iterator_type: sequence
output_dir: exp/lm_train_lm_char
ngpu: 1
seed: 0
num_workers: 1
num_att_plot: 3
dist_backend: nccl
dist_init_method: env://
dist_world_size: null
dist_rank: null
local_rank: 0
dist_master_addr: null
dist_master_port: null
dist_launcher: null
multiprocessing_distributed: false
cudnn_enabled: true
cudnn_benchmark: false
cudnn_deterministic: true
collect_stats: false
write_collected_feats: false
max_epoch: 200
patience: null
val_scheduler_criterion:
- valid
- loss
early_stopping_criterion:
- valid
- loss
- min
best_model_criterion:
- - valid
- loss
- min
keep_nbest_models: 1
grad_clip: 5.0
grad_clip_type: 2.0
grad_noise: false
accum_grad: 1
no_forward_run: false
resume: true
train_dtype: float32
use_amp: false
log_interval: null
unused_parameters: false
use_tensorboard: true
use_wandb: false
wandb_project: null
wandb_id: null
pretrain_path: null
init_param: []
freeze_param: []
num_iters_per_epoch: null
batch_size: 1000
valid_batch_size: null
batch_bins: 1000000
valid_batch_bins: null
train_shape_file:
- exp/lm_stats/train/text_shape.char
valid_shape_file:
- exp/lm_stats/valid/text_shape.char
batch_type: folded
valid_batch_type: null
fold_length:
- 150
sort_in_batch: descending
sort_batch: descending
multiple_iterator: false
chunk_length: 500
chunk_shift_ratio: 0.5
num_cache_chunks: 1024
train_data_path_and_name_and_type:
- - dump/raw/srctexts_with_spk
- text
- text
valid_data_path_and_name_and_type:
- - dump/raw/valid_srctexts_with_spk
- text
- text
allow_variable_data_keys: false
max_cache_size: 0.0
max_cache_fd: 32
valid_max_cache_size: null
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Interface-Engineered Li<sub>7</sub>La<sub>3</sub>Zr<sub>2</sub>O<sub>12</sub>-Based Garnet Solid Electrolytes with Suppressed Li-Dendrite Formation and Enhanced Electrochemical Performance
High grain-boundary resistance, Li-dendrite formation, and electrode/Li interfacial resistance are three major issues facing garnet-based solid electrolytes. Herein, interfacial architecture engineering by incorporating 1-butyl-1-methylpyrrolidinium bis(trifluoromethylsulfonyl) imide (BMP-TFSI) ionic liquid into a garnet oxide is proposed. The “soft” continuous BMP-TFSI coating with no added Li salt generates a conducting network facilitating Li+ transport and thus changes the ion conduction mode from point contacts to face contacts. The compacted microstructure suppresses Li-dendrite growth and shows good interfacial compatibility and interfacial wettability toward Li metal. Along with a broad electrochemical window larger than 5.5 V and an Li+ transference number that practically reaches unity, LiNi0.8Co0.1Mn0.1O2/Li and LiFePO4/Li solid-state batteries with the hybrid solid electrolyte exhibit superior cycling stability and low polarization, comparable to those with commercial liquid electrolytes, and excellent rate capability that is better than those of Li-salt-based ionic-liquid electrolytes.Accepted Author ManuscriptRST/Storage of Electrochemical Energ
Kaiso-deficient mice show resistance to intestinal cancer
Kaiso is a BTB domain protein that associates with the signaling molecule p120-catenin and binds to the methylated sequence mCGmCG or the nonmethylated sequence CTGCNA to modulate transcription. In Xenopus laevis, xKaiso deficiency leads to embryonic death accompanied by premature gene activation in blastulae and upregulation of the xWnt11 gene. Kaiso has also been proposed to play an essential role in mammalian synapse-specific transcription. We disrupted the Kaiso gene in mice to assess its role in mammalian development. Kaiso-null mice were viable and fertile, with no detectable abnormalities of development or gene expression. However, when crossed with tumor-susceptible Apc(Min/+) mice, Kaiso-null mice showed a delayed onset of intestinal tumorigenesis. Kaiso was found to be upregulated in murine intestinal tumors and is expressed in human colon cancers. Our data suggest that Kaiso plays a role in intestinal cancer and may therefore represent a potential target for therapeutic intervention
Li Yu xi qu zhong de li shi cheng xian yu min jian mian xiang
M.Phil.As one of the most important playwrights in late imperial China, Li Yu and his plays have long been discussed by researchers. However, many of them have underestimated the significance of Li Yu’s double identity of being, simultaneously, a member of the literati and a professional playwright of the urban theatre. Focusing on the representations of history in Li Yu’s plays, this thesis aims to explore how he negotiated influence from the two identities in his works. It is argued that in most of these plays he managed to deliver his care for the commoner audience, including providing them with theatrical entertainment and a mirror of daily life during the Ming-Qing transition, while expressing his personal concerns and feelings as a literatus.There are seven chapters in this thesis. Chapter One reviews the research history on Li Yu in the past century and raises the above topic of negotiation in question. Chapter Two to Five focus on four of Li Yu’s plays in chronological order, namely Qingzhong pu, Qianzhong lu, Liang xumei and Wanli yuan. All of the four plays were written meticulously as a kind of history, local or national. These four chapters illustrate the ways in which Li Yu combined his personal feelings, reflections on history, empathy with the common people, and equally important, his dramatic artistry. In Chapter Six, Qilin ge and Niutou shan were treated as examples of how popular legends about heroic figures in history such as Qin Qiong and Yue Yun were recreated by Li Yu for the commercial urban theatre in Suzhou. Chapter seven concludes the above discussions.The personal feelings and social cares shown in Li Yu’s plays came from real-life issues. Li not only recorded historical changes and social problems of his time, but also expressed his attitude towards the Qing government after the fall of Ming. By examining Li Yu’s attitude, this research also sheds light on Li Yu’s state of mind in later life, which has seldom been mentioned in the study of this dramatist.李玉(約1611-1677)為明末清初最重要的劇作家之一,學界對其近一世紀的研究已有豐碩成果,然而關於李玉文人與職業劇作家雙重身分對其創作的影響卻未有詳細的討論。故此,本文將視野聚焦在李玉劇作中對歷史的呈現,從文本內部、觀眾接受、外在社會情況等方面,探討其雙重身分在呈現兩種不同的目的與關注時之協調,發掘劇中所寄託的個人情感與民間面向,並觀察當中的變化。本文第一章梳理李玉研究之發展脈絡,提出個人關注的問題。第二至第五章按脫稿時間之先後,分章討論《清忠譜》、《千忠錄》、《兩鬚眉》、《萬裡圓》四部「以曲為史」之作所寄託之個人感懷與反思,及當中所體現的對民間之關懷。第六章以《麒麟閣》與《牛頭山》為李玉以歷史故事入劇之代表,探討李玉如何以劇場重現著名歷史故事,為民間觀眾提供娛樂。第七章就前述各劇之間的內部聯繫,及李玉個人心境與民間面向的變化軌跡作總結。李玉劇作中的個人寄託與對民間的關懷來自對現實的關注。它們不僅見證其身處的時代與社會之轉變,入清後之作更承載個人對易代、對清廷態度的變化。本文欲藉對李玉心態之剖析,填補學界對其後半生心境變化討論上的空白,加深對李玉其人的認識,亦為李玉研究提出就其身分與心態作進一步發展的新方向。劉美宜.Thesis M.Phil. Chinese University of Hong Kong 2017.Includes bibliographical references (leaves 162-173).Abstracts in English and Chinese.Title from PDF title page (viewed on February 17, 2020).Liu Meiyi
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