14 research outputs found

    Experimental Study of the Influences of Orientation and Altitude on Pyrolysis and Ignition of Wood

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    On account of limited attention paid to the influence of orientation and altitude in previous research, the pyrolysis and ignition characteristics of wood in different orientations and altitudes were investigated experimentally. Two orientations were explored: vertical and horizontal. In addition, experiments were conducted in Lhasa and in Hefei, which are at very different altitudes. Ignition time, mass loss rate, and surface temperature are discussed. Compared with those in the horizontal orientation, shorter ignition times, faster mass loss rates, and lower surface temperatures were observed in the vertical orientation. In addition, there are shorter ignition times, faster mass loss rates, and higher surface temperatures in Lhasa (high altitude) than in Hefei (low altitude). </jats:p

    Deficits Of Synaptic Functions In Hippocampal Slices Prepared From Aged Mice Null α7 Nicotinic Acetylcholine Receptors

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    Alpha 7 (α7) nicotinic acetylcholine receptor (α7-nAChR) is one of most high expressed nAChR subtypes in the brain. The activation of nAChRs enhances animal cognitive, learning and memory abilities. However, the role of genetic knockout (KO) of α7-nAChRs in animal cognition-associated behaviors is still obscure. An early report showed that α7-nAChR KO mice did not exhibit behavioral phenotypes, concerning the roles of α7-nAChRs in normal, cognition-associated behaviors. Later, α7-nAChR KO mice were found a deficit in animal spatial discrimination. The roles of α7-nAChRs in the alterations of hippocampal synaptic function during aging process are largely unknown. Here, we address this question by examining synaptic function using field potential recording in hippocampal slice preparations from adult (12-14 months old) and aged (22-24 months old) α7-nAChR KO and age-matched wild-type (WT) mice. We found that compared to aged WT mice, aged α7-nAChR KO mice exhibited significantly reduced size of evoked field synaptic potential and impaired long-term potentiation (LTP) in hippocampal CA3-CA1 synapses. However, adult α7-nAChR KO mice did not show a clear deficit in LTP although the basic synaptic transmission was also reduced compared to adult WT mice. In both age groups, there was no significant difference of paired-pulse facilitation between α7-nAChR KO and WT mice. Collectively, this study provides direct evidence, for the first time, that the impaired synaptic function occurs in aged α7-nAChR KO mice, suggesting an importance of α7-nAChRs in maintaining cognitive function during aging process. © 2014 Elsevier Ireland Ltd

    Experimental study of the effect of spark power on piloted ignition of wood at different altitudes

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    Generally, a continuous spark is used in piloted-ignition experiments on combustible materials. However, the potential effect of the spark’s power in such experiments, has been ignored in previous studies. In this article, experiments are carried out to assess the effect of spark power on the ignition characteristics of fir at different altitudes characterized by atmospheric pressures of 0.77 and 1.0 atm. It is concluded that ignition time becomes shorter with an increase of spark power. With a rise in spark power, the mass flux at ignition and the critical heat flux decline in the ignition process. Ignition time is found to be more sensitive to spark power in lower altitudes. </jats:p
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