16 research outputs found

    Gene Network Landscape of the Ciliate Tetrahymena thermophila

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    Background: Genome-wide expression data of gene microarrays can be used to infer gene networks. At a cellular level, a gene network provides a picture of the modules in which genes are densely connected, and of the hub genes, which are highly connected with other genes. A gene network is useful to identify the genes involved in the same pathway, in a protein complex or that are co-regulated. In this study, we used different methods to find gene networks in the ciliate Tetrahymena thermophila, and describe some important properties of this network, such as modules and hubs. Methodology/Principal Findings: Using 67 single channel microarrays, we constructed the Tetrahymena gene network (TGN) using three methods: the Pearson correlation coefficient (PCC), the Spearman correlation coefficient (SCC) and the context likelihood of relatedness (CLR) algorithm. The accuracy and coverage of the three networks were evaluated using four conserved protein complexes in yeast. The CLR network with a Z-score threshold 3.49 was determined to be the most robust. The TGN was partitioned, and 55 modules were found. In addition, analysis of the arbitrarily determined 1200 hubs showed that these hubs could be sorted into six groups according to their expression profiles. We also investigated human disease orthologs in Tetrahymena that are missing in yeast and provide evidence indicating that some of these are involved in the same process in Tetrahymena as in human. Conclusions/Significance: This study constructed a Tetrahymena gene network, provided new insights to the properties of this biological network, and presents an important resource to study Tetrahymena genes at the pathway level

    Study on Disaster Controlling for Water Contamination of Severe Cr-contaminated Sites on Jialing River

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    AbstractA severe Cr-contaminated site was left after the demolition of a Chemical plant. Based on the preliminary monitoring results and related literature data, this paper studied how to prevent and control the possible contamination from the site to Jialing River effectively, which is building an intercept contamination dam in the side of the contaminated site along Jialing River and constructing leachate collection system in the site. This is the antifouling effect: in the same stratum of the same elevation, the Cr6+content inside the intercept contamination dam (soil:144.8mg/kg∼827.4mg/kg, leaching solution: 7.3mg/L∼55.1mg/L) is higher than that of the outside (soil:10.4mg/kg∼64.9mg/kg, leaching solution: 0.27mg/L∼0.63mg/L); Water level of monitoring hole inside the dam is higher than that of the outside; the water level difference is 3.26m to 5.39m. The disaster controlling for the site provides security for the later contamination remediation and the river environment protection

    Experimental Study on Cleaning and Detoxification of Chromium in Construction Waste

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    AbstractBy selecting varieties of factors, designing experiment in groups and other methods, the cleaning and detoxification of chromium in construction† waste has been studied. Experimental results show that: When particle diameter is larger than 1cm, chromium and content are volatile in waste. On the opposite, the effect of particle size on the detoxification of waste is not significantly when it is smaller than 1cm. In addition, the type and concentration of detergent have a great influence on cleaning and detoxifying. Detoxification effects on chromium of citric acid (0.1mol/L, 0.5mol/L) and concentration hydrochloric acid (0.5mol/L, 1mol/L) are very efficient, and removal rate is up to 90%. Citric acid, oxalic acid, concentrated hydrochloric acid, and concentrated acetic acid have the best effect on Cr6+ removal works. Removal rate is more than 99%

    Boosted CO<sub>2</sub> reduction using ultra-thin TiO<sub>2</sub> photocatalyst films on nanocavities

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    We created an ultra-thin film photocatalytic light absorber (UFPLA) with 2 similar to 22-nm-thick TiO2 films. The UFPLA structure conquered the intrinsic trade-off between optical absorption and charge carrier extraction efficiency and therefore boosted CO2 reduction efficiency. (C) 2019 The Author(s

    Robust circular polarization of indirect Q-K transitions in bilayer 3R-W S2

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    | openaire: EC/H2020/820423/EU//S2QUIPValley-contrasting Berry curvature and orbital magnetic moment have led to highly selective circular polarization of direct excitons at the K valleys in transition-metal dichalcogenides. In addition to K valleys, Q valleys, another critical point in the conduction band, also possess well-defined but distinct magnetic moment. Being akin to the direct excitons at K valleys, indirect excitons associated with Q (K) valleys in the conduction (valence) band could allow circular polarization in principle. Here, we report an experimental observation of the circular polarization of indirect Q-K transitions in noncentrosymmetric bilayer 3R-WS2. In stark contrast to the circular polarization of direct excitons which depolarizes with increasing lattice temperature, the circular polarization of indirect Q-K excitons is extremely robust and independent on the temperature. Such robust circular polarization can be understood as follows: The spin-orbit coupling in the Q valley is much stronger than that in the K point of the conduction band, significantly suppressing the temperature induced valley depolarization. Our results open up opportunities for exotic valleytronics and quantum information processing applications.Peer reviewe
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