7,312 research outputs found
The Jackson Laboratory (JAX) - Kumar Lab Mouse Strain Survey of Behavior in the Open Field Behavior (Video Dataset)
No full textA video library of mouse behavior in the open field. We test genetically diverse mouse strains. This dataset can be used for computational ethology based analysis of animal behavior
Oncogenic role of miR-223 in Notch3 induced T Cell Acute Lymphoblastic Leukemia
No full textThis work was supported by the European Union (NotchIT ITN Project; FP7-MC-ITN 215761
Book Review: Anchalesh Kumar (ed.), Globalization, Environment and Quality of Life
No full text Anchalesh Kumar (ed.), Globalization, Environment and Quality of Life. Delhi: Vivek Prakashan, 2015, 475 pp., ₹875 (hardback), ISBN 978-81-70004-321-8. </jats:p
Biocatalytic route to C-3?-azido/-hydroxy-C-4?-spiro-oxetanoribonucleosides
No full textThe lipase, Novozyme®-435, exclusively deacetylates the 5-O-acetyl over 4-C-acetyloxymethyl group of almost identical reactivity in 5-O-acetyl-4-C-acetyloxymethyl-3-azido-3-deoxy-1,2-O-isopropylidene-?-D-ribofuranose that led to the development of first and efficient synthesis of 3?-azido-/3?-amino-C-4?-spiro-oxetanoribonucleosides T, U, C and A in 20–24% overall yields. The X-ray study on the compound obtained by tosylation of lipase-mediated monodeacetylated product unambiguously confirmed the point of diastereoselective monodeacetylation on diacetoxy-azido-ribofuranose derivative. The capability of Novozyme®-435 for selective deacylation of 5-O-acetyl group in 5-O-acetyl-4-C-acetyloxymethyl-3-O-benzyl-1,2-O-isopropylidene-?-D-ribofuranose recently discovered by us has been successfully used for the synthesis of C-4?-spiro-oxetanoribonucleosides A and C in good yields. These results clearly indicate that the broader substrate specificity and highly selective capability of Novozyme®-435 for carrying out acetylation/deacetylation reactions can be utilized for the development of environment friendly selective methodologies in organic synthesis
Assessing financial well-being of merchants by analyzing behavioral patterns in historical transactions
No full textThis study focuses on a new approach to estimate financial wellbeing indicators for merchants, by looking at behavioral patterns of their customers using transaction history. The transaction data for about 10,000 merchants in a specific country, was analyzed in terms of diversity and propensity of their customers using factors like age, distance travelled to shop, time of the day for shopping, day of the week for shopping, educational status, gender etc. These factors were used as independent variables to predict the financial well-being of merchants, particularly in two dimensions – total revenue and consistency in revenue, both relative to other merchants in the same industry. The merchants were then also divided into the categories of Essential, Non- essential and Luxury goods depending on the industry they belong to and it was interesting to observe the contrast across categories. The results suggest that behavioral patterns could be used to augment current methods of calculating credit score
Targeted therapy of epigenomic regulatory mechanisms controlling the epithelial to mesenchymal transition during tumor progression
No full textThe epithelial-to-mesenchymal transition (EMT) is a reversible change in cell phenotype that plays a crucial role during normal development and cancer metastasis. EMT imparts embryonic epithelial cells with the ability to migrate and to give rise to organs or tissues at distant sites. During cancer progression, the same developmental process is utilized in an analogous manner to enable cancer cells to move to distant organs and form metastases. The reversion of EMT via the mesenchymal-to-epithelial transition (MET) appears to be required for the formation of secondary tumors at distal sites. The plasticity of epigenomic modifications that control the transcriptional program of cells enables cells to switch back and forth from epithelial and mesenchymal phenotypes during these transitions. Here, we review the interplay between complex epigenomic regulatory mechanisms and various transcription factors involved in EMT leading to changes in gene expression and cell phenotype. We also discuss the way that a deeper understanding of the epigenomic regulation of EMT might shed light onto the process of cancer progression and reveal new targets for novel and more specific anticancer epigenomic therapies.Deutsche Krebshilfe [109088]; Deutsche Forschungsgemeinschaft [JO 815/3
Chilli thrips Scirtothrips dorsalis Hood (Insecta: Thysanoptera: Thripidae)
No full textRevised! EENY463, an 11-page fact sheet by Vivek Kumar Jha, Dakshina R. Seal, and Garima Kakkar, is part of the Featured Creatures collection. It describes this new introduced insect pest that is an important pest of vegetable, ornamental, and fruit crops — synonymy, distribution, identification, life cycle and biology, hosts, damage, disease transmission, management. Includes references. Published by the UF Department of Entomology and Nematology, October 2009. Revised January and August, 2010.
EENY463/IN833: Chilli thrips Scirtothrips dorsalis Hood (Insecta: Thysanoptera: Thripidae) (ufl.edu
Chilli thrips Scirtothrips dorsalis Hood (Insecta: Thysanoptera: Thripidae)
No full textRevised! EENY463, an 11-page fact sheet by Vivek Kumar Jha, Dakshina R. Seal, and Garima Kakkar, is part of the Featured Creatures collection. It describes this new introduced insect pest that is an important pest of vegetable, ornamental, and fruit crops — synonymy, distribution, identification, life cycle and biology, hosts, damage, disease transmission, management. Includes references. Published by the UF Department of Entomology and Nematology, October 2009. Revised January and August, 2010.
EENY463/IN833: Chilli thrips Scirtothrips dorsalis Hood (Insecta: Thysanoptera: Thripidae) (ufl.edu
Hierarchical Composite Materials: Materials, Manufacturing, Engineering/ Kaushik Kumar, J. Paulo Davim.
No full textIn English.Includes bibliographical references and index.Hierarchical Composite Materials provides an in-depth analysis of a class of advanced composites that have properties that are anisotropic due to structural organization at different length scales. Chapters address how ordering occurs from the atomic-scale up to the microstructure and how control of these factors leads to the final materials' properties. Manufacturing procedures, properties, and applications of different functionally graded materials are discussed in detail. This book is ideal for materials scientists, mechanical engineers, chemists and physicists.Zindani, Divya / Kumar, Kaushik / Davim, J. Paulo -- Abdulrahman, Kamardeen O. / Akinlabi, Esther T. / Mahamood, Rasheedat M. -- Mahamood, R. M. / Akinlabi, E. T. / Owolabi, G. M. / Abdulrahman, K. O. -- Alaaeddin, M. H. / Sapuan, S. M. / Yusoff, M. Z. M. / Zainudin, E. S. / Al-Oqla, Faris M. -- Subramaniam, Savita K. / Gaba, Vivek Kumar / Bhowmick, Shubhankar -- Hien, Ta Duy -- Karsh, P. K. / Mukhopadhyay, T. / Dey, S. -- Singh, Akant Kumar / Siddhartha / Singh, Prashant Kumar -- Sondhi, Lakshman / Sanyal, Subhashis / Saha, Kashinath / Bhowmick, Shubhankar -- Frontmatter -- Preface -- Contents -- List of Contributing Authors -- Editors’ Biography -- 1. Fabrication of functionally graded materials: A review / 2. Manufacturing of aluminium composite materials: A review / 3. Advanced manufacturing of compositionally graded composite materials: An overview / 5. Natural fiber composites as functionally graded materials for advanced applications / 6. Temperature distribution in functionally graded longitudinal fins of varying geometry / 7. Analytic approach for transient response of functionally graded rectangular plates including the higher-order shear deformation effects / 8. Fuzzy-based frequency response function analysis of functionally graded plates / 9. Transmission efficiency of glass fiber-filled functionally graded material-based PA66 composite spur gears / 10. Approximate solution of functionally graded thick cylinders / Index1 online resource (188 p.
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