210,242 research outputs found
Data from: Pulsed peritoneal dialysis in Sprague-Dawley rats
<p>Peritoneal dialysis treatment is hampered by low small solute clearances compared to hemodialysis. Previous data have indicated that stirring or mixing of the dialysate could possibly improve small solute diffusion, presumably by avoiding the formation of stagnant layers in the dialysate directly adjacent to the peritoneal membrane. In an experimental model of peritoneal dialysis in Sprague-Dawley rats, we compared a 60 min standard PD-exhange with a novel exchange technique called pulsed peritoneal dialysis in which the dialysate in pulsed in and out of the peritoneal cavity without the addition of fresh dialysis fluid. Samples of dialysate were taken directly after instillation and after 60 min. Samples of blood were taken before and after dialysis.</p><p>Funding provided by: Baxter (Sweden)<br>Crossref Funder Registry ID: https://ror.org/05mw5ed57<br>Award Number: </p><p>Funding provided by: Lund University<br>Crossref Funder Registry ID: https://ror.org/012a77v79<br>Award Number: YF 2020-YF0056</p><p>Funding provided by: IngaBritt och Arne Lundbergs Forskningsstiftelse<br>Crossref Funder Registry ID: https://ror.org/049zxm836<br>Award Number: </p>
GENA: databas för svenska avhandlingar inom genusforskning
The GENA database was initiated in 2001 by KvinnSam, Gothenburg University Library, on behalf of the National Secretariat for Gender Research. The database was finalized in 2022 and covers the period from 1960 to 2022.
The database includes doctoral theses in women's, men's, and gender studies from Swedish academic institutions. This encompasses research that problematizes how gender is made, constructed, and created at different levels in culture and society. Women's, men's, and gender studies include gender equality research (investigating injustices in society related to gender and proposing measures to address them), women's studies (women and femininity), feminist research (emancipatory research with a focus on power), men's studies/masculinity research (men and masculinity), and queer research (critique of heteronormativity).
The database is available as an Excel file with multiple sheets (.xlsx), as semicolon separated values (.csv), and as a PostgreSQL dump file that may be used to reconstruct the original database configuration (.sql).Databasen GENA startade 2001 av KvinnSam, Göteborgs universitetsbibliotek på uppdrag av Nationella sekretariatet för genusforskning. Databasen avslutades 2022 och täcker perioden 1960-2022.
Databasen innehåller doktorsavhandlingar inom kvinno-, mans- och genusforskning från svenska lärosäten. Med detta menas forskning som problematiserar hur genus görs, konstrueras och blir till, på olika nivåer, i kultur och samhälle. Till kvinno-, mans- och genusforskning räknas jämställdhetsforskning (forskning kring orättvisor i samhället som har med kön att göra och förslag på åtgärder mot detta), kvinnoforskning (kvinnor och femininitet), feministisk forskning (emancipatorisk forskning med maktfokus), mansforskning/maskulinitetsforskning (män och maskulinitet) och queerforskning (kritik av heteronormativitet).
Databasen finns tillgänglig dels som en Excelfil med flera ark (.xlsx), dels som motsvarande tabeller som semikolonseparerade värden (.csv) samt dels som en PostgreSQL-dump som kan användas för att återskapa originaldatabasen (.sql)
Den nationella SOM-undersökningen 1990
The questionnaire for the fifth study in the series of annual SOM-surveys was divided into seven subject fields: mass media; politics and society; energy, nuclear power and environment; Sweden´s relation to other countries; Islam; leisure; and background. The SOM surveys contains a core of questions asked annually. New questions in SOM90 dealt with good qualities in daily papers; priority of news from different areas; confidence in Swedish mass media; whether different activities should be handled by the public sector or by private enterprises, associations, or by individuals; government intervention; opinions on different suggestions in the Swedish environmental debate, and own environmental activities; attitudes toward Islam.
Purpose:
The main purpose is to establish time series that enable researchers to analyse how various changes in society affect people's attitudes and behaviour.Detta är den femte undersökningen i serien Riks-SOM, en nationell frågeundersökning med syfte att kartlägga den svenska allmänhetens vanor och attityder på temat samhälle, opinioner och medier.
1990 års undersökning består av sju sammanhållna delar: massmedier; politik och samhälle; energi, kärnkraft och miljö; Sveriges förhållande till omvärlden; islam; fritid; samt bakgrundsuppgifter.
Många av frågorna har ställts i tidigare SOM-undersökning, men ett antal frågor har tillkommit. Nya frågeställningar i Riks-SOM 1990 gäller viktiga egenskaper hos en dagstidning; prioritering av nyheter från olika områden; förtroende för de svenska massmedierna; huruvida olika verksamheter bör skötas av stat och kommun eller av privata företag, föreningar eller enskilda; statens styrning av kommuner, näringsliv och enskilda; åsikter om olika förslag i den svenska miljödebatten, samt egna miljöaktiviteter; och inställning till islam.
Genom att frågor ställts på ett likartat sätt över tid finns det i SOM-serien tidsserier om bland annat medieanvändning, politik, kärnkraftsopinion och förtroende för olika samhällsinstitutioner och grupper.
Syfte:
Huvudsyftet är att etablera tidsserier som gör det möjligt att analysera hur olika samhällsförändringar påverkar människors attityder och beteenden
Data from: Digital PCR quantification of ultrahigh ERBB2 copy number identifies poor breast cancer survival after trastuzumab
<p>HER2/ERBB2 evaluation is necessary for treatment decision-making in breast cancer (BC), however current methods have limitations and considerable variability exists. DNA copy number (CN) evaluation by droplet digital PCR (ddPCR) has complementary advantages for HER2/ERBB2 diagnostics. In this study, we developed a single-reaction multiplex ddPCR assay for determination of ERBB2 CN in reference to two control regions, CEP17 and a copy-number-stable region of chr. 2p13.1, validated CN estimations to clinical in situ hybridization (ISH) HER2 status, and investigated the association of ERBB2 CN with clinical outcomes. 909 primary BC tissues were evaluated and the area under the curve for concordance to HER2 status was 0.93 and 0.96 for ERBB2 CN using either CEP17 or 2p13.1 as reference, respectively. The accuracy of ddPCR ERBB2 CN was 93.7% and 94.1% in the training and validation groups, respectively. Positive and negative predictive value for the classic HER2 amplification and non-amplification groups was 97.2% and 94.8%, respectively. An identified biological "ultrahigh" ERBB2 ddPCR CN group had significantly worse survival within patients treated with adjuvant trastuzumab for both recurrence-free survival (hazard ratio, HR: 3.3; 95% CI 1.1–9.6; <em>p</em> = 0.031, multivariable Cox regression) and overall survival (HR: 3.6; 95% CI 1.1–12.6; <em>p</em> = 0.041). For validation using RNA-seq data as a surrogate, in a population-based SCAN-B cohort (NCT02306096) of 682 consecutive patients receiving adjuvant trastuzumab, the ultrahigh-ERBB2 mRNA group had significantly worse survival. Multiplex ddPCR is useful for ERBB2 CN estimation and ultrahigh ERBB2 may be a predictive factor for decreased long-term survival after trastuzumab treatment.</p><p>Funding provided by: Swedish Research Council<br>Crossref Funder Registry ID: https://ror.org/03zttf063<br>Award Number: </p><p>Funding provided by: Swedish Cancer Society<br>Crossref Funder Registry ID: https://ror.org/0527jb766<br>Award Number: </p><p>Funding provided by: Governmental Funding of Clinical Research within National Health Service*<br>Crossref Funder Registry ID: <br>Award Number: </p><p>Funding provided by: Lund University<br>Crossref Funder Registry ID: https://ror.org/012a77v79<br>Award Number: </p><p>Funding provided by: Gunnar Nilsson Cancer Foundation<br>Crossref Funder Registry ID: https://ror.org/00292rj97<br>Award Number: </p><p>Funding provided by: European Commission<br>Crossref Funder Registry ID: https://ror.org/00k4n6c32<br>Award Number: MSCA-COFUND-2016 754299</p><p>Funding provided by: Fru Berta Kamprads stiftelse<br>Crossref Funder Registry ID: https://ror.org/04wv8j283<br>Award Number: </p><p>Funding provided by: European Commission<br>Crossref Funder Registry ID: https://ror.org/00k4n6c32<br>Award Number: MSCA-COFUND-2018 847583</p><div>RNA-sequencing data for breast tumors was generated within the SCAN-B initiative. The processed data file contains ERBB2 original, log2-transformed, and mean adjusted (correcting for 2 group protocols dUTP & TruSeq_*) transcripts per kilobase million (TPM) values as well as all clinical variables used in the analysis. See README and associated publication for details of SCAN-B RNA-seq data generation and data processing.</div>
Host lifestyle and parasite interspecific facilitation mediate co-infection in a species-poor host-parasite system
The morphometric and geometric morphometric data underlying results of the article Kmentová et al. 2024 published in the OIKOS journal under the title Host lifestyle and parasite interspecific facilitation mediate co-infection in a species-poor host-parasite system.Vlaamse Interuniversitaire Raad. awardNumber:null. https://ror.org/00q3h2974Hasselt University. awardNumber:null. https://ror.org/04nbhqj75Hasselt University. awardNumber:null. https://ror.org/04nbhqj75Hasselt University. awardNumber:null. https://ror.org/04nbhqj75Czech Science Foundation. awardNumber:null. https://ror.org/01pv73b02Hasselt University. awardNumber:null. https://ror.org/04nbhqj75Research Foundation - Flanders. awardNumber:null. https://ror.org/03qtxy027Czech Science Foundation. awardNumber:null. https://ror.org/01pv73b0
Host lifestyle and parasite interspecific facilitation mediate co-infection in a species-poor host-parasite system
The morphometric and geometric morphometric data underlying results of the article Kmentová et al. 2024 published in the OIKOS journal under the title Host lifestyle and parasite interspecific facilitation mediate co-infection in a species-poor host-parasite system.Vlaamse Interuniversitaire Raad. awardNumber:null. https://ror.org/00q3h2974Hasselt University. awardNumber:null. https://ror.org/04nbhqj75Hasselt University. awardNumber:null. https://ror.org/04nbhqj75Hasselt University. awardNumber:null. https://ror.org/04nbhqj75Czech Science Foundation. awardNumber:null. https://ror.org/01pv73b02Hasselt University. awardNumber:null. https://ror.org/04nbhqj75Research Foundation - Flanders. awardNumber:null. https://ror.org/03qtxy027Czech Science Foundation. awardNumber:null. https://ror.org/01pv73b0
Phenotypic microarray data for three bacterial BCA that were exposed to six different wavelengths
Phenotypic microarray data (PM 1 and PM 2) involving three bacterial strains, Bacillus amyloliquefaciens DSM7, Pseudomonas chlororaphis 58003, Streptomyces griseoviridis CBS904.68, under six light treatments (Darkness, 420, 460, 530, 630, 660 nm at 50 μmol per m2 per second) with six replicates for each. Each csv file is the raw data for one light treatment and all three bacteria. The output is in OmniLog values, which were measured as a colour change of tetrazolium blue due to respiration. Measurements for the dark treatment occurred every 15 min for 96 hours. For the other treatments manual measurements were taken every: 0, 6, 10, 24, 30, 48, 54, 72, and 96 h post inoculation (hpi). Measurements for the light treatments in the OmniLog incubator took one hour. For more information, please see the README file
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity
<p>Isocitrate Dehydrogenase 1 (IDH1) is the most commonly mutated metabolic gene across human cancers. Mutant IDH1 (mIDH1) generates the oncometabolite (R)-2-hydroxyglutarate, disrupting enzymes involved in epigenetics and other processes. A hallmark of IDH1-mutant solid tumors is T cell exclusion, whereas mIDH1 inhibition in preclinical models restores anti-tumor immunity. Here, we define a cell-autonomous mechanism of mIDH1-driven immune evasion. IDH1-mutant solid tumors show striking, selective hypermethylation and silencing of the cytoplasmic dsDNA sensor, CGAS, compromising innate immune signaling. mIDH1 inhibition restores DNA demethylation, derepressing CGAS and transposable element (TE) subclasses. dsDNA produced by TE-reverse transcriptase activates cGAS, triggering viral mimicry and stimulating anti-tumor immunity. Thus, we demonstrate that mIDH1 epigenetically suppresses innate immunity and link endogenous reverse transcriptase activity to the mechanism of action of an FDA-approved oncology drug.</p><p>Funding provided by: American Cancer Society<br>ROR ID: https://ror.org/02e463172<br>Award Number: PF-20-136-01-TBG</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: P50CA127003</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: 1R01CA280085-01A1</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: R01CA219670</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: R01CA215498</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: P01CA117969</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: K99CA277576</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: K12CA0903354</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: F30CA271634</p><p>Funding provided by: TargetCancer Foundation<br>ROR ID: https://ror.org/02hk1y795<br>Award Number: </p><p>Funding provided by: Massachusetts Life Sciences Center<br>ROR ID: https://ror.org/033km2469<br>Award Number: </p><p>Funding provided by: Cholangiocarcinoma Foundation<br>ROR ID: https://ror.org/04fp9z389<br>Award Number: </p><p>Funding provided by: Japan Society for the Promotion of Science<br>ROR ID: https://ror.org/00hhkn466<br>Award Number: </p><p>Funding provided by: Uehara Memorial Foundation<br>ROR ID: https://ror.org/00gc20a07<br>Award Number: </p><p>Funding provided by: International Human Frontier Science Program Organization<br>ROR ID: https://ror.org/02ebx7v45<br>Award Number: LT0018/2022-L</p><p>Funding provided by: Daiichi Sankyo Foundation of Life Science<br>ROR ID: https://ror.org/05j492n53<br>Award Number: </p><p>Funding provided by: Nakatomi Foundation<br>ROR ID: https://ror.org/0196vdc40<br>Award Number: </p><p>Funding provided by: Burroughs Wellcome Fund<br>ROR ID: https://ror.org/01d35cw23<br>Award Number: </p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: K22CA237752</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: R01CA258586</p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: U19CA264504</p><p>Funding provided by: Cancer Prevention and Research Institute of Texas<br>ROR ID: https://ror.org/0003xa228<br>Award Number: RR190034</p><p>Funding provided by: Sontag Foundation<br>ROR ID: https://ror.org/01pkpj777<br>Award Number: </p><p>Funding provided by: Cholangiocarcinoma Foundation<br>ROR ID: https://ror.org/04fp9z389<br>Award Number: </p><p>Funding provided by: National Cancer Institute<br>ROR ID: https://ror.org/040gcmg81<br>Award Number: 1K99CA245194-01</p><p>Funding provided by: Massachusetts General Hospital<br>ROR ID: https://ror.org/002pd6e78<br>Award Number: </p><p>Funding provided by: Cholangiocarcinoma Foundation<br>ROR ID: https://ror.org/04fp9z389<br>Award Number: </p><p>Funding provided by: The Mochida Memorial Foundation<br>Award Number: </p><p>Funding provided by: Massachusetts General Hospital<br>ROR ID: https://ror.org/002pd6e78<br>Award Number: </p><p>Funding provided by: Lubin Family Foundation*<br>Crossref Funder Registry ID: <br>Award Number: </p><p>Funding provided by: Cholangiocarcinoma Foundation<br>ROR ID: https://ror.org/04fp9z389<br>Award Number: </p><p>Funding provided by: Massachusetts General Hospital<br>ROR ID: https://ror.org/002pd6e78<br>Award Number: </p><p>Supplemental table for the analyses of transposable elements from mutant IDH1 cancer cell lines treated with mIDH1 inhibitor by two pipelines (TEtranscript and SQuIRE)</p>
Data from: Grazing herbivores reduce herbaceous biomass and fire activity across African savannas
<p>Fire and herbivory interact to alter ecosystems and carbon cycling. In savannas, herbivores can reduce fire activity by removing grass biomass, but the size of these effects and what regulates them remain uncertain. To examine grazing effects on fuels and fire regimes across African savannas, we combined data from herbivore exclosure experiments with remotely sensed data on fire activity and herbivore density. We show that, broadly across African savannas, grazing herbivores substantially reduce both herbaceous biomass and fire activity. The size of these effects was strongly associated with grazing herbivore densities and, surprisingly, was mostly consistent across different environments. A one-zebra increase in herbivore biomass density (~100 kg/km<sup>2</sup> of metabolic biomass) resulted in a ~53 kg/ha reduction in standing herbaceous biomass and a ~0.43 percentage point reduction in burned area. Our results indicate that fire models can be improved by incorporating grazing effects on grass biomass.</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: MSB-1802453</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-2224317</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: EAR-2204471</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-0516145</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-0841917</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-0516094</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-1712786</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-0709880</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: OISE-0852961</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-1355122</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-0444071</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-1930820</p><p>Funding provided by: National Science Foundation of Sri Lanka<br>Crossref Funder Registry ID: https://ror.org/010xaa060<br>Award Number: DEB-1547679</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-1930763</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-2018405</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: NSF-2132265</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: LTREB 97-07477</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: LTREB 03-16402</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: LTREB 08-16453</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: LTREB 12-56034</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: LTREB 19-31224</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: IOS-1656527</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-2225088</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: DEB-1145861</p><p>Funding provided by: National Science Foundation<br>Crossref Funder Registry ID: https://ror.org/021nxhr62<br>Award Number: BSC-1461728</p><p>Funding provided by: Sherwood Family Foundation*<br>Crossref Funder Registry ID: <br>Award Number: </p><p>Funding provided by: Natural Sciences and Engineering Research Council<br>Crossref Funder Registry ID: https://ror.org/01h531d29<br>Award Number: </p><p>Funding provided by: University of Florida<br>Crossref Funder Registry ID: https://ror.org/02y3ad647<br>Award Number: </p><p>Funding provided by: University of British Columbia<br>Crossref Funder Registry ID: https://ror.org/03rmrcq20<br>Award Number: </p><p>Funding provided by: Princeton University<br>Crossref Funder Registry ID: https://ror.org/00hx57361<br>Award Number: </p><p>Funding provided by: Smithsonian Institution<br>Crossref Funder Registry ID: https://ror.org/01pp8nd67<br>Award Number: </p><p>Funding provided by: National Geographic Society<br>Crossref Funder Registry ID: https://ror.org/04bqh5m06<br>Award Number: 4691-91</p><p>Funding provided by: United States Fish and Wildlife Service<br>Crossref Funder Registry ID: https://ror.org/04k7dar27<br>Award Number: 98210-0-G563</p><p>Funding provided by: Cameron Schrier Foundation*<br>Crossref Funder Registry ID: <br>Award Number: </p><p>Funding provided by: Carr Foundation*<br>Crossref Funder Registry ID: <br>Award Number: </p><p>Funding provided by: National Geographic Society<br>Crossref Funder Registry ID: https://ror.org/04bqh5m06<br>Award Number: 9106-12</p>
Theoretically predicted CO2 lines near 700 nm not observed
Authors:Balashov, Aleksandr – ORCID: 0000-0001-9537-1805 – Nicolaus Copernicus University – ROR: https://ror.org/0102mm775Raj, Ankit – ORCID: 0000-0002-2495-3354 – National Yang Ming Chiao Tung University – ROR: https://ror.org/00se2k293Wójtewicz, Szymon – ORCID: 0000-0001-8600-0543 – Nicolaus Copernicus University – ROR: https://ror.org/0102mm775Ciuryło, Roman – ORCID: 0000-0003-2638-0403 – Nicolaus Copernicus University – ROR: https://ror.org/0102mm775Lisak, Daniel – ORCID: 0000-0001-5545-7989 – Nicolaus Copernicus University – ROR: https://ror.org/0102mm775Bielska, Katarzyna – ORCID: 0000-0002-4218-9193 – Nicolaus Copernicus University – ROR: https://ror.org/0102mm775Contact person:Szymon Wójtewicz – Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziądzka 5, PL-87-100 Toruń, Poland – ROR: https://ror.org/0102mm775.Data set related to the publication "Theoretically predicted CO2 lines near 700 nm not observed".The data is available under a CC BY 4.0 license.Link to related publication: https://doi.org/10.1063/5.0152996DOI: 10.1063/5.0152996All data were collected in 2023 at temperature 296 K and pressures 150 or 200 Torr using the optical frequency comb assisted, Pound–Drever–Hall locked, frequency-stabilized cavity ring-down spectrometer.Deposited data:Data_experimental_spectra - folder containing files with experimental data for three carbon dioxide bands lying between 14300 and 14550 cm^(-1). The first column in the file is the frequency, and the second column are losses (1/(c*tau)).</p
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