6,576 research outputs found
A Comprehensive Literary Review of Bronchial Asthma (Zīq-Un-Nafas Shu‘Bī) and its Management in the Unani System of Medicine
No full textLung diseases are among the leading global health concerns, affecting more than 500 million people and accounting for nearly 10% of annual deaths. Asthma, derived from the Greek verb aazein meaning “to pant,” was first mentioned in Homer’s Iliad and later recognized in the Corpus Hippocraticum as a medical condition. Initially used for general breathlessness, it was more clearly defined in the 19th century by Henry Hyde Salter as a disorder characterized by episodic breathing difficulty due to airway narrowing. In the Unani System of Medicine (USM), asthma is classified under Amrāḍ-i-Majāri (respiratory disorders). This paper explores the Unani perspective of bronchial asthma through classical references and modern research. Literature search included classical texts such as Al-Qanoon, Kitab al-Hawi, Zakhira Thabit bin Qara, Kulliyat, and Tibbe Akbar, along with modern databases (PubMed, Google Scholar, Science Direct, Web of Science, and Scopus). A total of 23 classical Unani books, 18 original research articles, and 34 review articles were reviewed. Scholars like Buqrat, Jalinus, Razi and Ibn Sina described asthma as Rabw, Buhr, and, Ḍῑq al-Nafas, and recommended single drugs (Adusa, Aslussus, Banafsha, Afteemoon, Unnab) and compound formulations (Sharbat-e-Banafsha, Sharbat-e-Ejaz, Sharbat-e-Unnab, Safoof-e-Dama). The collected data were analysed and systematically organized to highlight the relevance of Unani approaches in asthma management.
Keywords: Amrāḍ-I-Majari, Ḍῑq al-Nafas, Asthma, lung disease, Rabw, US
The optimization of actions in the joint operation of objects or systems, taking into account synergetic effects
No full textМеньших Валерий Владимирович – доктор физико-математических наук, профессор, профессор кафедры математики и моделирования систем, Воронежский институт МВД России, г. Воронеж, Российская Федерация, ORCID iD: https://orcid.org/0000-0001-9235-4997, e-mail: [email protected].
Никитенко Виталий Алексеевич – преподаватель кафедры математики и моделирования систем, Воронежский институт МВД России, г. Воронеж, Российская Федерация, ORCID iD: https://orcid.org/0009-0006-1948-3817, e-mail: [email protected]. Menshikh Valery Vladimirovich is Dr. Sc. (Physics and Mathematics), Professor, Professor of the Mathematical and Modeling System Department, Voronezh Institute of the Ministry of Internal Affairs of Russia, Voronezh, Russian Federation, ORCID iD: https://orcid.org/0000-0001-9235-4997, e-mail: [email protected].
Nikitenko Vitaly Alekseevich is Assistant of the Mathematical and Modeling System Department, Voronezh Institute of the Ministry of Internal Affairs of Russia, Voronezh, Russian Federation, ORCID iD: https://orcid.org/0009-0006-1948-3817, e-mail: [email protected].Разрабатывается модель координации действий объектов или систем в условиях их совместного взаимодействия, приводящего к возникновению синергетических эффектов на основе общей автоматной модели данных объектов или систем. Описание общей автоматной модели осуществляется на основе агрегирования отдельных составляющих, представляющих собой отдельные объекты или системы, которым также соответствуют автоматные модели. Как частный пример рассматривается описание действий силовых подразделений, которые участвуют в ликвидации чрезвычайных обстоятельств. На основе общей автоматной модели и описания действий подразделений разработан численный метод оптимизации последовательности действий, в основе которого лежит схема ветвей и границ, корректность которой подтверждается тем, что при взаимодействии отдельных объектов или систем могут возникать альтернативные действия и, следовательно, полный перебор является не целесообразным. This article develops a model for coordinating the actions of objects or systems in joint interaction leading to synergetic effects based on a common automatic model of these objects or systems. The description of the general automaton model is carried out based on the aggregation of individual components representing separate objects or systems, which also correspond to automaton models. As a special example, the actions of law enforcement units that participate in emergency situations is considered. On the basis of a general automaton model and a description of the actions of units, a numerical method for optimizing the sequence of actions has been developed based on a scheme of branches and boundaries. The effectiveness is confirmed by the fact that alternative actions may occur during the in-teraction of individual objects or systems and, therefore, a complete search is not advisable
Pandemic Thoughts: Decolonising COVID [Blog Post]
No full textGeetha Marcus - ORCID: 0000-0001-5610-5344
https://orcid.org/0000-0001-5610-5344Item not available in this repository.https://www.qmu.ac.uk/campus-life/blogs/staff-dr-geetha-marcus/pandemic-thoughts
Protective Effects of Interleukin-1 Inhibition With Anakinra in Mouse Models of Ischemic Stroke With and Without Reperfusion
No full textSevere brain ischemia is associated with life-threatening edema and inflammation. Interleukin-1 is a crucial mediator of inflammation, and its blockade showed benefits in experimental stroke. We studied anakinra, a modified recombinant human interleukin-1 receptor antagonist, in mouse models of moderate to severe ischemia/reperfusion and large hemispheric infarctions. Due to anakinra's short half-life, we used a novel subcutaneous infusion protocol and tested 2 drug doses.Study funded by Instituto de Salud Carlos III, Ministerio de Salud (grant PI21/00966 to Dr Urra); Ministerio de Ciencia, Innovación y Universidades MCIN/AEI/10.13039/501100011033 and “ERDF: A way of making Europe” by the “European Union” (grants PID2020‐113202RB‐I00 and PID2023‐150949OB‐I00 to Dr Planas, and grant PID2021‐125106OB‐C31 to Dr Arostegui); “Fundació La Marató de TV3” (grant 202330‐10) to Dr Planas, and the RICORS‐Ictus network of Instituto de Salud Carlos III (RD21/0006/0013 and RD24‐0009‐0002 to Dr Chamorro and RD21/0006/0014 and RD24‐0009‐0003 to Dr Salom).Peer reviewe
Finanz- und Rechnungswesen: Jahrbuch 2019
No full textIn diesem Jahrbuch analysieren hochkarätige und erfahrene Experten aktuelle Herausforderungen und Entwicklungen im Finanz- und Rechnungswesen; zudem werden Strategien und Wege zu deren Lösung aufgezeigt.
Die Herausgeber Prof. Dr. Reto Eberle, Prof. Dr. David Oesch und Prof. Dr. Dieter Pfaff vom Institut für Betriebswirtschaftslehre der Universität Zürich sowie ihr namhaftes Autorenteam aus Wissenschaft und Praxis versorgen Sie wieder mit topaktuellen, praxisorientierten Themen rund um das Finanz- und Rechnungswesen in der Schweiz
Gammapatía monoclonal de significado renal: la clave es el diagnóstico precoz
No full textY Monoclonal gammopathy of renal significance is a clinical-pathological entity grouping renal disorders secondary to the secretion of a monoclonal immunoglobulin synthesized by a B-cell-derived clone and/or plasma cells in a patient with no diagnostic criteria for multiple myeloma. This term applies to a concept recently introduced owing to the need to differentiate this entity from monoclonal gammopathy of undetermined significance, given the negative prognostic impact of its high morbidity and mortality resulting from both renal and systemic involvement, occasionally even progressing to advanced chronic kidney disease. The renal damage occurs via both direct pathogenic mechanisms, with the deposition of the monoclonal protein in different renal structures, as well as indirect mechanisms, acting as an autoantibody provoking dysregulation of the alternative complement pathway. The detection of this monoclonal protein and an early hematologic study are essential, as is the need for a kidney biopsy to establish the associated nephropathological diagnosis. Consequently, this then leads to the start of specific hematologic treatment to detain the production of the monoclonal protein and minimize renal and systemic injury.La gammapatía monoclonal de significado renal es una entidad clínico-patológica que agrupa los trastornos renales secundarios a la secreción de una inmunoglobulina monoclonal sintetizada por un clon derivado de células B y/o células plasmáticas en un paciente sin criterios de diagnóstico de mieloma múltiple. Este término se aplica a un concepto introducido recientemente debido a la necesidad de diferenciar esta entidad de la gammapatía monoclonal de significado incierto, teniendo en cuenta el impacto pronóstico negativo de su alta morbilidad y mortalidad a causa de la afectación tanto renal como sistémica, llegando en ocasiones a progresar a una enfermedad renal crónica avanzada. El daño renal se produce tanto por mecanismos patogénicos directos, con el depósito de la proteína monoclonal en diferentes estructuras renales, como por mecanismos indirectos, actuando como un autoanticuerpo que provoca la desregulación de la vía alternativa del complemento. La detección de esta proteína monoclonal y un estudio hematológico precoz son imprescindibles, así como la necesidad de una biopsia renal para establecer el diagnóstico nefropatológico asociado. En consecuencia, esto lleva al inicio de un tratamiento hematológico específico para detener la síntesis de la proteína monoclonal y minimizar la lesión renal y sistémica.S
AMČR - dokument C-200912982N-DT-0009
No full textStav: 3Označení: DR-12982-10442Popis: Pohled od JZ.Objekt/kontext: D
AMČR - dokument C-200912982O-DT-0009
No full textStav: 3Označení: DR-12982-19892Popis: V část plochy.Objekt/kontext: P I-
- …
