1,721,773 research outputs found
Anisotropic Type I string compactification, winding modes and large extra dimensions
No full textWe discuss the structure of general Anisotropic Compactification in Type I D=4, N=1 string theory. It is emphasized that, in this context, a possible interpretation of M_{Planck} as ``dual'' to (at least) one of the Kaluza-Klein or Windings Modes could provide interesting interpretations of the ``physical scales'' and the GUT coupling. Some of the scenarios presented here are strictly connected with the phenomenological proposal of TeV-scale gravity (i.e. millimiter compactification). We show that in this scenario new and probably dominant effects should arise from the presence of ``low-energy'' Winding Modes of usual SM particles. Stringent bounds on the Planck mass in 4+n dimensions are derived from the existing experimental limits on massive replicas of SM gauge bosons. Non-observation of Winding Modes at the planned accelerators could provide stronger bounds on the 4+n dimensional Planck mass than those from graviton emission into the bulk. Some comments on other possible phenomenological interesting scenarios are addressed
L’approvazione della Direttiva sul lavoro mediante piattaforme digitali: prima lettura
Full text linkThe Directive on improving working conditions in platform work has
been finally adopted by national labour ministers at the Council meeting on 11
March 2024. The Directive has the ambitious aim of improving the minimum
standards recognised by European and national legislations for platform
workers and advancing the protection of natural persons with regard to the
processing of personal data and algorithmic work management. Still pending its
formal approval, the Authors offer a first analysis of the new provisions to
regulate and protect platform work
Appearance and disappearance signals at a beta-beam and a super-beam facility
No full textIn this letter we present the study of the eightfold degeneracy in the measurement including both appearance and disappearance channels. We analyse, for definiteness, the case of a standard low- -Beam and a 4 MWatt SPL Super-Beam facility, both aiming at a UNO-like Mton water Cerenkov detector located at the Frejus laboratory, km. In the -Beam case, the \nue disappearance channel does not improve the measurement when a realistic (i.e. 2%) systematic error is included. In the Super-Beam case, the \numu disappearance channel could, instead, be quite useful in reducing the impact of the eightfold degeneracy in the measurement, especially once the error on the atmospheric mass difference is fully taken into account in the fit
Neoadjuvant chemotherapy for locally advanced gastric cancer: Where we stand; An Italian single center perspective
No full textBackground/Aim: Neoadjuvant or perioperative chemotherapy is the standard treatment for locally advanced gastric cancer. However, in Eastern countries this is still debated. The aim of our study was to evaluate the survival impact of neoadjuvant chemotherapy. Patients and Methods: A total of 60 patients who underwent preoperative chemotherapy were compared to patients with locally advanced gastric cancer that underwent upfront surgery. Results: Median survival of the entire group curatively treated was 41 months with a median progression-free survival of 38 months. By excluding patients with stage IV disease from the neoadjuvant group, a statistically significant difference was reached both in terms of overall survival and disease-free survival. By subdividing patients according to pTNM stages, neoadjuvant patients showed better survival in stage I and II. Conclusion: Neoadjuvant chemotherapy could be an effective treatment for locally advanced disease. However, randomized studies are still needed to fully understand its role and identify patients that will benefit from it
Survival comparison in gastric cancer patients between 7th and 8th edition of the AJCC TNM staging system: The first western single center experience
No full textBackground: The objective of this study was to compare the 7th and the 8th edition of American Joint Committee on Cancer staging system (AJCC TNM) in terms of better stratification in our gastric cancer resected patients. Methods and materials: A retrospective analysis of a single western center series was made. Patients who underwent surgery from January 2004 to December 2016 were enrolled in the study. We compared survival rates across patients classified according to the 7th and the 8th AJCC TNM staging system. Results: Among 295 patients we observed 9.8% stage migration according the 8th edition. Of these 2.1% and 7.9% of patients showed respectively a higher and a lower stage. 5 years Overall Survival (5Y-OS) according to the 8th edition for stage IIIB and IIIC were 32% versus 9% showing a better stratification compared to the 7th edition in which 5Y-OS were respectively 26% versus 22%. Conclusion: Restaging system seems to improve survival rate discrimination in particular comparing stage IIIB and stage IIIC; whereas in stage IIIA this is not so clear. More studies are necessary to confirm these data
nu(mu) disappearance at the SPL, T2K-I and the Neutrino Factory
No full textWe study the disappearance channel at T2K-phase I and the SPL and analyse the achievable reduction of present uncertainties in and . We analyse the impact of discrete ambiguities in sign() and sign(). We show how the disappearance channel at the Neutrino Factory is complementary to the ``golden'' and ``silver'' appearance channels and can be used to reduce the eightfold-ambiguity problem in ()
Summary of golden measurements at a v-factory
No full textThe precision and discovery potential of a neutrino factory based on muon storage rings is summarized. For three-family neutrino oscillations, we analyze how to measure or severely constraint the angle , CP violation, MSW effects and the sign of the atmospheric mass difference . The appearance of ``wrong-sign muons'' at three reference baselines is considered: 732 km, 3500 km and 7332 km. We exploit the dependence of the signal on the neutrino energy, and include as well realistic background estimations and detection efficiencies. The optimal baseline turns out to be (3000 km)
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