130 research outputs found

    Exploring fragment space: Library construction, screening and fragment growing

    Get PDF
    Leurs, R. [Promotor]Esch, I.J.P. de [Copromotor

    Design and Synthesis of New Histamine H4 Receptor Ligands

    Get PDF
    Leurs, R. [Promotor]Esch, I.J.P. de [Copromotor

    Trypanosoma brucei phosphodiesterase B1 as a drug target for Human African Trypanosomiasis

    Get PDF
    Leurs, R. [Promotor]Esch, I.J.P. de [Promotor

    Fragment-based drug discovery approaches towards novel 5-HT3 receptor ligands

    Get PDF
    Leurs, R. [Promotor]Esch, I.J.P. de [Copromotor

    Fragment-based drug design of small molecule EPHA4 kinase inhibitors

    Get PDF
    Leurs, R. [Promotor]Esch, I.J.P. de [Copromotor

    The acetylcholine binding protein as a template for the ligand binding domains of the homologous nicotinic receptors

    Get PDF
    Leurs, R. [Promotor]Smit, A.B. [Promotor]Esch, I.J.P. de [Copromotor

    In silico Medicinal Chemistry: Investigating GPCRs: key regulators of signal transduction and cell function

    Get PDF
    Leurs, R. [Promotor]Esch, I.J.P. de [Promotor]Graaf, C. de [Copromotor

    Structure-based design of AChBP ligands, new insights and applications

    Get PDF
    Leurs, R. [Promotor]Esch, I.J.P. de [Copromotor

    Design and synthesis of small nonpeptidergic ligands for the human cytomegalovirus-encoded receptor US28

    Get PDF
    Leurs, R. [Promotor]Smit, M.J. [Copromotor]Esch, I.J.P. de [Copromotor

    Design and Preparation of New Ligands Interacting with the Histamine H4 Receptor

    Get PDF
    Leurs, R. [Promotor]Haaksma, E.E.J. [Promotor]Esch, I.J.P. de [Copromotor
    corecore