1,776,544 research outputs found
CK-12
No full textCK-12 is comprised of free, open access resources for both teachers and students including online textbooks, lesson plans, worksheets, and much more. The site has both a student and teacher view, and on the homepage, subjects are broken down by category. For example, if visiting the probability category under the math subject, lessons plans for counting sets, theoretical and experimental probability, and probability and statistics are available for use in teacher or student view. Lesson plans include activities, videos, practice worksheets, and many include study aids with flashcards. One of the highlights of the site is PLIX, which stands for Play, Learn, Interact, Xplore. PLIX includes interactive activities and is available for all subjects on the site, though using this option does require a free account with CK-12. Also available on CK-12 are its FlexBooks, which are free online textbooks that include text, interactive lessons, worksheets, and embedded PLIX lessons. CK-12 is accessible via a web browser but is also available as an app on iOS and Android devices
CK-666 and CK-869 differentially inhibit Arp2/3 iso-complexes.
No full textThe inhibitors, CK-666 and CK-869, are widely used to probe the function of Arp2/3 complex mediated actin nucleation in vitro and in cells. However, in mammals, the Arp2/3 complex consists of 8 iso-complexes, as three of its subunits (Arp3, ArpC1, ArpC5) are encoded by two different genes. Here, we used recombinant Arp2/3 with defined composition to assess the activity of CK-666 and CK-869 against iso-complexes. We demonstrate that both inhibitors prevent linear actin filament formation when ArpC1A- or ArpC1B-containing complexes are activated by SPIN90. In contrast, inhibition of actin branching depends on iso-complex composition. Both drugs prevent actin branch formation by complexes containing ArpC1A, but only CK-869 can inhibit ArpC1B-containing complexes. Consistent with this, in bone marrow-derived macrophages which express low levels of ArpC1A, CK-869 but not CK-666, impacted phagocytosis and cell migration. CK-869 also only inhibits Arp3- but not Arp3B-containing iso-complexes. Our findings have important implications for the interpretation of results using CK-666 and CK-869, given that the relative expression levels of ArpC1 and Arp3 isoforms in cells and tissues remains largely unknown
ctuning/ck: many enhancements to handle adaptive Docker containers via CK
No full textadded module "docker.template" to support adaptive CK containers
added rebuild function to module:docker to rebuild images (#145)
added support for multiple Docker tags in module:docker . See example: https://github.com/octoml/mlops/tree/main/docker/ck-template-mlperf
added "default_org" key in a CK Docker entry meta to specify default organization
added "outdated" and "aging" keys in Docker images to warn user about the status of a given Docker container
added main CK and MLPerf repositories to Zenodo to ensure reproducibilty
added common function "tested" to mark CK entries as tested, i.e. "ck tested docker:mlperf-inference-v0.7.openvino
ctuning/ck: added --force_version to "ck detect soft"
No full textAdded --force_version to "ck detect soft" to force version.
Useful to automate autodetection of imagenet, for example
ctuning/ck: minor improvements and fixes
No full text<ul>
<li>allowed local widget to fetch data from cKnowledge.org (or other) website: <a href="https://github.com/ctuning/ck/pull/93">https://github.com/ctuning/ck/pull/93</a></li>
<li>automatically print API of redirected functions (ck <action> <module> --help)</li>
<li>improved module API printing</li>
<li>added pypi download stats</li>
<li>fixed minor problem with "ck renew repo" - now takes already existing UID instead of generating a new one</li>
</ul>
mlcommons/ck: Stable release for MLCommons CK v2.6.0
No full textThis is a stable release of the MLCommons CK framework with a few minor fixes to automate MLPerf inference benchmark v2.0+ submissions
ctuning/ck: basic support for inheritance of CK entries
No full textadded support for basic inheritance in CK entries via "_base_entry" key. Useful to simplify program, package and soft modules. See ticket #143.
added program.template, soft.template and package.template modules to describe base entries for inheritance
ctuning/ck: minor extensions
No full textadded --tags to "ck find" action to be able to search for entries by tags and return their paths
added module:doc to abstract documentatio
ctuning/ck-web: Tagging stable version 2019.10.13
No full textCollective Knowledge web extension to browse CK repositories, visualize interactive graphs and articles, render CK-based websites, implement simple web services with JSON API (for example to crowdsource experiments or unify access to DNN). Demos of interactive articles, graphs and crowdsourced experiments
ctuning/ck-ml: Stable release
No full textAggregation of CK components and workflows from the community for ML Systems in one repository. They are also uploaded to the cKnowledge platform
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